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You searched for +publisher:"Universitat Internacional de Catalunya" +contributor:("Guirao Garriga, Xavier"). One record found.

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1. Juvany Gómez, Montserrat. Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós.

Degree: Departament de Medicina, 2015, Universitat Internacional de Catalunya

Previous studies demonstrated that increased levels of C-reactive protein (CRP) after colo-rectal surgery are correlated to postoperative organ-space surgical site infection (OS-SSI) even at 48 hours time point. Such early inflammatory response might suggest that intraoperative haemodynamic factors might influence intestinal anastomosis healing. Objective: To evaluate the correlation between early postoperative venous lactate, CRP at 48 hours and intraoperative haemodynamics and the incidence of OS-SSI in patients operated on elective colorectal surgery with anastomosis. Materials and methods. From March 2013 to August 2014, all patients undergoing colorectal surgery with anastomosis were prospectively included. Levels of venous lactate were measured at the end of surgery (L-PO) and at 6 (L-6) and 24 hours afterwards (L-24). CRP levels at postoperative 48 hours (CRP-48) were also measured. We compared lactate levels and CRP values in patients with and without OS-SSI infection. Proportion of time that patients developed intraoperative systolic hypotension (SBP<100 mmHg) or tachycardia (>90 bpm) were also assessed. Data are summarized as mean ± SD. To analyze data, Student t-test and a logistic regression model with L-0 and CRP-48 with a ROC curve of this model were performed. Results. One hundred patients were included, with an age of 69±11 years-old. Forty-four percent of patients were operated by laparoscopic approach. Eleven out of 100 patients (11%) complained OS-SSI. OS-SSI patients had significantly higher venous lactate levels at L-PO and at L-24 (3,2 vs 1,5, p<0,001 and 1,8 vs 1,2, p=0,0002, mmol/L, respectively). Overall, patients with L-PO >2,5 mmol/L had higher CRP-48 levels (140±85 vs. 78±57 mg/L, respectively, p=0,001). With the logistic regression model with L-PO and CRP-48 and ROC curve of this model: in patients with more than 0,26 of probability, OS-SSI should be discarded (AUC 0,899). Analysing haemodynamics behaviour, patients who developed OS-SSI remained hypotensive (50 % vs 30%, p=0,03) and tachycardic (18% vs 5%, p=0,02) for a longer period of time. Conclusions. Early postoperative venous lactate and CRP at 48 hours correlated to OS-SSI appearance. Determination of biological markers and haemodynamics goal-oriented intraoperative management might improve the postoperative outcome. Advisors/Committee Members: false (authoremailshow), Guirao Garriga, Xavier (director), Badia Pérez, Josep Maria (director), false (authorsendemail).

Subjects/Keywords: Lactat venós; Infecció òrgan-espai; Cirurgia colo-rectal; Cirugia Abdominal; 61

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APA (6th Edition):

Juvany Gómez, M. (2015). Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós. (Thesis). Universitat Internacional de Catalunya. Retrieved from http://hdl.handle.net/10803/362920

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Juvany Gómez, Montserrat. “Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós.” 2015. Thesis, Universitat Internacional de Catalunya. Accessed September 22, 2020. http://hdl.handle.net/10803/362920.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Juvany Gómez, Montserrat. “Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós.” 2015. Web. 22 Sep 2020.

Vancouver:

Juvany Gómez M. Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós. [Internet] [Thesis]. Universitat Internacional de Catalunya; 2015. [cited 2020 Sep 22]. Available from: http://hdl.handle.net/10803/362920.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Juvany Gómez M. Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós. [Thesis]. Universitat Internacional de Catalunya; 2015. Available from: http://hdl.handle.net/10803/362920

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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