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You searched for +publisher:"Université Catholique de Louvain" +contributor:("Verhelst, Robert"). One record found.

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Université Catholique de Louvain

1. Willemet, Marie. Blood flow modeling for patient-specific bypass surgery in lower-limb arteries.

Degree: 2012, Université Catholique de Louvain

Every day in Belgium, at least one or two people will undergo a bypass surgery in the lower-limb arteries. This medical procedure consists of replacing an occluded section of the leg arteries with an artificial vessel, in order to allow blood to flow downwards of this blockage. Even though this intervention is very common, failure of this treatment within five years reaches up to 60%. In order to improve our understanding of the causes of bypass failure, one approach is to study the local hemodynamics (i.e. the blood flow circulation) in these vessels, as this factor strongly influences the initiation and progression of arterial diseases. This thesis addresses this objective by modeling the patient-specific arterial hemodynamics. As each patient is characterized by his own physiology (e.g. morphology, severity of the disease) and is treated by a bypass graft of fixed characteristics (e.g. material, length, location of the anastomoses), each clinical case needs to be considered individually. In the first part of our work, blood pressure, velocity and flow rate in the network of arteries are modeled with a one-dimensional model of the arteries and lumped windkessel models of the secondary and distal vessels. The 18 parameters of this coupled model are then computed in order to reflect the pathological condition of the patient. Thanks to the set-up of an experimental protocol of data acquisition, in-vivo measurements of hemodynamics have been acquired on 25 patients operated with bypass surgery. The comparison of these in-vivo signals with simulations from the numerical model enabled us to improve and to validate our patient-specific numerical model. In the second part of this thesis, the dynamic of blood is considered as impulses of waves which are generated by the contractions of the heart, and which propagate throughout the arterial network. By using the wave intensity analysis method, we analyzed and characterized these waves in the pathological arteries of the leg, and emphasized the effects of the bypass.

(FSA 3)  – UCL, 2012

Advisors/Committee Members: UCL - SST/IMMC/MEMA - Applied mechanics and mathematics, Marchandise, Emilie, Remacle, Jean-François, Pardoen, Thomas, Verhelst, Robert, Flaud, Patrice, Legat, Vincent, Alastruey Arimon, Jordi, Khir, Ashraf.

Subjects/Keywords: Hemodynamics modeling; Bypass surgery; Cardiovascular system; In-vivo data acquisition; One-dimensional model; Zero-dimensional model; Wave Intensity Analysis; Parameter estimation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Willemet, M. (2012). Blood flow modeling for patient-specific bypass surgery in lower-limb arteries. (Thesis). Université Catholique de Louvain. Retrieved from http://hdl.handle.net/2078.1/109517

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Willemet, Marie. “Blood flow modeling for patient-specific bypass surgery in lower-limb arteries.” 2012. Thesis, Université Catholique de Louvain. Accessed October 19, 2019. http://hdl.handle.net/2078.1/109517.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Willemet, Marie. “Blood flow modeling for patient-specific bypass surgery in lower-limb arteries.” 2012. Web. 19 Oct 2019.

Vancouver:

Willemet M. Blood flow modeling for patient-specific bypass surgery in lower-limb arteries. [Internet] [Thesis]. Université Catholique de Louvain; 2012. [cited 2019 Oct 19]. Available from: http://hdl.handle.net/2078.1/109517.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Willemet M. Blood flow modeling for patient-specific bypass surgery in lower-limb arteries. [Thesis]. Université Catholique de Louvain; 2012. Available from: http://hdl.handle.net/2078.1/109517

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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