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You searched for +publisher:"Universidade Estadual de Campinas" +contributor:("Monteiro, Juliana Castro"). Showing records 1 – 3 of 3 total matches.

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Universidade Estadual de Campinas

1. Freitas, Karine Moura, 1986-. Efeitos da Ciclosporina A associada ou não à Heteropterys tomentosa (A. Juss.) no fígado, rim, testículo, epidídimo, próstata e timo de ratos Wistar = Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus: Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus.

Degree: 2014, Universidade Estadual de Campinas

Abstract: Cyclosporin A (CsA) is an immunosuppressive drug used after organ transplantation and against auto immune diseases. Despite CsA widely use as immunosuppressant, this drug causes diverse side effects as: nephrotoxicity, hepatotoxicity and male reproductive organs (testis and ventral prostate) impairment. Those CsA-related side effects are probably related to the CsA pro oxidant properties that causes imbalance among reactive oxygen species generation and antioxidant enzymes production. Heteropterys tomentosa, native plant from Brazilian cerrado, a savanna-like biome, is popularly used as tonic and stimulant of brain functions and as an aphrodisiac plant. H. tomentosa¿s efficiency against CsA side effects to the testis and ventral prostate has been scientifically proved. Moreover, H. tomentosa either reduced the alterations caused by CsA to plasma biochemical parameters that are hepatotoxicity markers. The aim of the present study was evaluate the effects of CsA to the liver, kidney, testis, epididymis, ventral prostate and thymus. If there are alterations CsA-induced, evaluate if H. tomentosa infusion alter these effects. Lastly we aimed to evaluate if H. tomentosa infusion interfere on CsA immunosuppressive capacity. CsA treatment for 21 days caused minor alterations to the liver tissue; this result was not observed after the administration of the infusion for 56 days. The simultaneous treatment with CsA and H. tomentosa caused hepatic alterations different from those observed in the animals treated with only CsA. The nephrotoxicity CsA-induce was time related; the kidney of animals treated with CsA had small substances accumulation (casts) on juxtamedullary tubules lumina, alteration to the proximal tubules were not evident. After 56 days of treatment there was huge casts on juxtamedullary tubules and some proximal tubules had vacuolization. These kidney¿s alterations were present in the groups treated with CsA and CsA+H. tomentosa. H. tomentosa administration did not caused alteration to the kidney tissue. The treatment with CsA, H. tomentosa and both simultaneously did not caused effects to the testis, however, CsA administration for 56 days caused alterations to the epididymis and ventral prostate; these alteration were not observe after the treatment with CsA+H. tomentosa. CsA caused reduction on the number of lymphocytes in the peripheral blood after the administration for 21 or 56 days, simultaneously with H. tomentosa or not. Furthermore, the thymus tissue had structural alterations caused by CsA, administrated alone or simultaneously to H. tomentosa (for 21 or 56 days). These results confirm CsA immunosuppression even after the administration with H. tomentosa simultaneously. The present study shows that CsA-induced effects to the kidney, epididymis and ventral prostate are time dependents. Moreover, the treatment with H. tomentosa reduced the alteration caused by CsA to the epididymis and ventral prostate. Finally, this study proved that H. tomentosa did not alter the immunosuppressant properties… Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Dolder, Mary Anne Heidi, 1943- (advisor), Universidade Estadual de Campinas. Instituto de Biologia (institution), Programa de Pós-Graduação em Biologia Celular e Estrutural (nameofprogram), Monteiro, Juliana Castro (committee member), Tomiosso, Tatiana Carla (committee member), Aguiar, Grasiela Dias de Campos Severi (committee member), Boer, Patricia Aline (committee member).

Subjects/Keywords: Fitoterapia; Heteropterys aphrodisiaca; Imunossupressão; Plantas medicinais; Phytotherapy; Heteropterys aphrodisiaca; Immunosuppression; Medicinal plants

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Freitas, Karine Moura, 1. (2014). Efeitos da Ciclosporina A associada ou não à Heteropterys tomentosa (A. Juss.) no fígado, rim, testículo, epidídimo, próstata e timo de ratos Wistar = Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus: Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/317836

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Freitas, Karine Moura, 1986-. “Efeitos da Ciclosporina A associada ou não à Heteropterys tomentosa (A. Juss.) no fígado, rim, testículo, epidídimo, próstata e timo de ratos Wistar = Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus: Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus.” 2014. Thesis, Universidade Estadual de Campinas. Accessed December 05, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317836.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Freitas, Karine Moura, 1986-. “Efeitos da Ciclosporina A associada ou não à Heteropterys tomentosa (A. Juss.) no fígado, rim, testículo, epidídimo, próstata e timo de ratos Wistar = Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus: Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus.” 2014. Web. 05 Dec 2020.

Vancouver:

Freitas, Karine Moura 1. Efeitos da Ciclosporina A associada ou não à Heteropterys tomentosa (A. Juss.) no fígado, rim, testículo, epidídimo, próstata e timo de ratos Wistar = Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus: Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus. [Internet] [Thesis]. Universidade Estadual de Campinas; 2014. [cited 2020 Dec 05]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317836.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Freitas, Karine Moura 1. Efeitos da Ciclosporina A associada ou não à Heteropterys tomentosa (A. Juss.) no fígado, rim, testículo, epidídimo, próstata e timo de ratos Wistar = Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus: Effect of Cyclosporin A, with or without Heteropterys tomentosa (A. Juss.) administration, on Wistar rats' liver, kidney, testis, epididymis, prostate and thymus. [Thesis]. Universidade Estadual de Campinas; 2014. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317836

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Universidade Estadual de Campinas

2. Vieira, Cristiano Pedrozo, 1986-. Efeito da nutrição terapêutica a base de Camellia sinensis (chá verde) e ração rica em glicina sobre a tendinite do tendão calcanear de rato = Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats: Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats.

Degree: 2015, Universidade Estadual de Campinas

Abstract: Therapeutic nutrition is the administration of some nutrients, in higher doses than those recommended for the daily food needs that can prevent dysfunctions and act as pharmacological agents. Glycine has large beneficial effects in inflammatory and tumor processes. Green tea made from leaves and buds of the Camellia sinensis plant, is the second most consumed beverage in the world. The economic and social interest has gained space in the market and currently its consumption is part of the daily routine of many people who use this drink as a therapeutic purpose. Green tea has antimutagenic, antidiabetic, anti-inflammatory, antioxidant, antimicrobial and hypocholesterolemic properties. Tendinitis is recognized as a clinical problem that motivates the scientific community to investigate treatments that help in restoring the functional properties of tendons. The present study investigated the effect of green tea and/or diet rich in glycine after 7 and 21 days of tendinitis collagenase-induced. Biochemical, molecular, morphological and biomechanical tests were developed. Furthermore, tenocytes in culture were treated with glycine after inflammation induced by TNF-?. Our tests in vivo showed high concentrations of hydroxyproline and glycosaminoglycans in glycine and green tea group in 21 days of treatment. In biomechanical assay, green tea and glycine diet groups in 21 days showed a high biomechanical loads bore before rupture. In addition, better organization of collagen fibers was observed in green tea group in 7 days. Biochemical and molecular analyzes of myotendinous junction showed that the inflammation installed in osteotendinious region can cause significant change in that region. Remarkable changes were noted in metalloproteinases (MMP) such as MMP-2, MMP-8 and MMP-9 in animals with tendinitis treated with or without glycine and green tea. In the in vitro study, tenocytes from Achilles tendon were treated with TNF-?, or not following treatment with glycine in the culture medium. Before and 24 hours after inflammation was added glycine. Tenocytes inflamed and treated with glycine showed expression of collagen type I close to the treated groups with glycine previously and after the inflammation when compared to the control group. All treated groups showed less glycine MMP-2 expression. The activity of MMP-9 was high only in the group treated with glycine for 48 hours. In the cell migration assay results in 24 hours of treatment were similar to the control group. In general, both glycine and green tea influenced the synthesis of the tendon components, improve the organization of the collagenous fibers, increase the load resistance of the inflamed tendon and consequently accelerate the remodeling process after inducing tendinitis. In addition, the treatment with glycine in tenocytes culture showed efficient reorganization of the extracellular matrix, confirming the results found in vivo Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Pimentel, Edson Rosa, 1949- (advisor), Universidade Estadual de Campinas. Instituto de Biologia (institution), Programa de Pós-Graduação em Biologia Celular e Estrutural (nameofprogram), Tomiosso, Tatiana Carla (committee member), Monteiro, Juliana Castro (committee member), Esquisatto, Marcelo Augusto Marretto (committee member), Oliveira, Silvia Borges Pimentel de (committee member).

Subjects/Keywords: Matriz extracelular; Inflamação; Tendinopatia; Fator de necrose tumoral alfa; Colágeno; Extracellular matrix; Inflammation; Tendinopathy; Tumor necrosis factor-alpha; Collagen

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Vieira, Cristiano Pedrozo, 1. (2015). Efeito da nutrição terapêutica a base de Camellia sinensis (chá verde) e ração rica em glicina sobre a tendinite do tendão calcanear de rato = Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats: Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/317356

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Vieira, Cristiano Pedrozo, 1986-. “Efeito da nutrição terapêutica a base de Camellia sinensis (chá verde) e ração rica em glicina sobre a tendinite do tendão calcanear de rato = Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats: Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats.” 2015. Thesis, Universidade Estadual de Campinas. Accessed December 05, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317356.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Vieira, Cristiano Pedrozo, 1986-. “Efeito da nutrição terapêutica a base de Camellia sinensis (chá verde) e ração rica em glicina sobre a tendinite do tendão calcanear de rato = Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats: Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats.” 2015. Web. 05 Dec 2020.

Vancouver:

Vieira, Cristiano Pedrozo 1. Efeito da nutrição terapêutica a base de Camellia sinensis (chá verde) e ração rica em glicina sobre a tendinite do tendão calcanear de rato = Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats: Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats. [Internet] [Thesis]. Universidade Estadual de Campinas; 2015. [cited 2020 Dec 05]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317356.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vieira, Cristiano Pedrozo 1. Efeito da nutrição terapêutica a base de Camellia sinensis (chá verde) e ração rica em glicina sobre a tendinite do tendão calcanear de rato = Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats: Effect of therapeutic nutrition on the basis of Camellia sinensis (green tea) and glycine-diet on the tendinitis of Achilles tendon of rats. [Thesis]. Universidade Estadual de Campinas; 2015. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317356

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Universidade Estadual de Campinas

3. Almeida, Marcos dos Santos de, 1980-. Análise de diferentes protocolos de acupuntura nos aspectos bioquímicos, ultraestruturais e organizacionais de tendões de ratos em processo de cicatrização = Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process: Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process.

Degree: 2015, Universidade Estadual de Campinas

Abstract: Several studies indicate that acupuncture (AC) has both local mechanotransductor and systemic anti-inflammatory (AI) effects. These effects could potentially accelerate the healing process. Therefore, the aim of this study was to analyze the effect of different protocols of AC on the biochemical, organizational and ultrastructural aspects of rat tendons during the healing process. Male Wistar rats at 60 days of age were divided into the following groups: not tenotomized or normal group (N), tenotomized group (T), tenotomized and submitted to AC at ST-36 point (ST36), tenotomized and submitted to AC at BL-57 point (BL57), tenotomized and submitted to manual AC at ST-36 and BL-57 points (SB) and tenotomized and submitted to electroacupuncture (EA) on the two points mentioned. The animals were euthanized on 7th, 14th and 21th days after injury. Thereafter, the Achilles tendons were collected, processed and analyzed to quantify non-collagenic proteins using the method of Bradford. For organizational analysis, it was quantified the collagen fibers birefringence by polarizing microscopy. In the ultrastructural analysis were measured the diameters of collagen fibrils and then histograms of distribution of these diameters were built as well as mass-average diameter - MAD - of collagen fibrils was calculated. The results showed that the associated use of ST-36 and BL-57 points increases both the birefringence of collagen fibers at 14th and 21th days and the MAD at the three periods analyzed. The reorganization of collagen fibrils also increased at 21th day with the application of the two points mentioned. However, the application of EA did not increase the birefringence or the reorganization of fibrils as well as decreased the MAD of fibrils at 21th after injury. Thus, we conclude that the use of manual AC at ST-36 and BL-57 points is effective in restoring the structural and ultrastructural properties of the collagen of tendons during the healing process. These results suggest strengthening the tendon structure with consequent increased resistance to re-rupture and the potential use of AC in rehabilitation protocols Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Pimentel, Edson Rosa, 1949- (advisor), Universidade Estadual de Campinas. Instituto de Biologia (institution), Programa de Pós-Graduação em Biologia Celular e Estrutural (nameofprogram), Tomiosso, Tatiana Carla (committee member), Monteiro, Juliana Castro (committee member), Junior, Wagner Costa Rossi (committee member), Sant'ana, Estela Maria Correia (committee member).

Subjects/Keywords: Cicatrização de feridas; Acupuntura; Eletroacupuntura; Eutanásia; Tendões; Ratos Wistar; Wound healing; Acupuncture; Electroacupuncture; Euthanasia; Tendons; Rats, Wistar

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Almeida, Marcos dos Santos de, 1. (2015). Análise de diferentes protocolos de acupuntura nos aspectos bioquímicos, ultraestruturais e organizacionais de tendões de ratos em processo de cicatrização = Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process: Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/317345

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Almeida, Marcos dos Santos de, 1980-. “Análise de diferentes protocolos de acupuntura nos aspectos bioquímicos, ultraestruturais e organizacionais de tendões de ratos em processo de cicatrização = Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process: Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process.” 2015. Thesis, Universidade Estadual de Campinas. Accessed December 05, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317345.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Almeida, Marcos dos Santos de, 1980-. “Análise de diferentes protocolos de acupuntura nos aspectos bioquímicos, ultraestruturais e organizacionais de tendões de ratos em processo de cicatrização = Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process: Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process.” 2015. Web. 05 Dec 2020.

Vancouver:

Almeida, Marcos dos Santos de 1. Análise de diferentes protocolos de acupuntura nos aspectos bioquímicos, ultraestruturais e organizacionais de tendões de ratos em processo de cicatrização = Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process: Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process. [Internet] [Thesis]. Universidade Estadual de Campinas; 2015. [cited 2020 Dec 05]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317345.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Almeida, Marcos dos Santos de 1. Análise de diferentes protocolos de acupuntura nos aspectos bioquímicos, ultraestruturais e organizacionais de tendões de ratos em processo de cicatrização = Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process: Analysis of different acupuncture protocols on biochemical, ultrastructural and organizational aspects of rats tendons in healing process. [Thesis]. Universidade Estadual de Campinas; 2015. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/317345

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.