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You searched for +publisher:"Universidade Estadual de Campinas" +contributor:("Merlo, Aloir Antonio"). Showing records 1 – 2 of 2 total matches.

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Universidade Estadual de Campinas

1. Godoi, Marla Narciso. Síntese de 4- e 5-arilprolinas através da reação de Heck-Matsuda e sua utilização como organocatalisadores em reações aldólicas e Mannich multicomponente: Synthesis of 4- and 5-aryl prolines via Heck-Matsuda reaction and their use as organocatalysts in aldol reaction and multicomponent Mannich.

Degree: 2010, Universidade Estadual de Campinas

Abstract: This work aimed at the development of efficient routes for the synthesis of aryl prolines with the Heck-Matsuda reaction as key step. The potential of these arylated amino acids as organocatalysts was evaluated through aldol and multicomponent Mannich reactions. In the first chapter results will be presented concerning the synthesis of 5-aryl prolines. The stereoselective preparation of these compounds employed the Heck-Matsuda reaction as key step and involved an enecarbamate derived from piroglutamic acid. The organocatalytic behavior of these amino acids was evaluated and one noted that its performance was inferior to that of L-proline. Due to this observation, derivatives of prolines arylated in C-4 were synthesized and tested as organocatalysts. The second chapter begins with studies on the performance of the C-4- arylated aryl kainoid xx as organocatalyst. This amino acid was initially tested in aldol reactions and presented an organocatalytic performance slightly superior to that of L-proline itself. Hence, 4-arylprolines were synthesized, exploring the Heck-Matsuda reaction with L-dehydroprolines as olefins, and their potential as organocatalysts was also investigated. In this moment of the work, a methodologic study concerning the preparation of monoarylated enecarbamates was performed. Employ of microwaves-based heating on the arylation reactions allowed significant reduction of reaction times. From a stereoselective methanol elimination from 4-arylated 2-methoxy-prolines, employing silane hydrides and BF3.Et2O, one could obtain cis-4-aryl-prolines in only three steps. Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Correia, Carlos Roque Duarte, 1953- (advisor), Universidade Estadual de Campinas. Instituto de Química (institution), Programa de Pós-Graduação em Química (nameofprogram), Merlo, Aloir Antonio (committee member), Cunha, Silvio do Desterro (committee member), Miranda, Paulo Cesar Muniz de Lacerda (committee member), Coelho, Fernando Antonio Santos (committee member).

Subjects/Keywords: Arilprolinas; Heck-Matsuda, reação de; Organocatálise; Aryl prolines; Heck-Matsuda reaction; Organocatalysis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Godoi, M. N. (2010). Síntese de 4- e 5-arilprolinas através da reação de Heck-Matsuda e sua utilização como organocatalisadores em reações aldólicas e Mannich multicomponente: Synthesis of 4- and 5-aryl prolines via Heck-Matsuda reaction and their use as organocatalysts in aldol reaction and multicomponent Mannich. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/249880

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Godoi, Marla Narciso. “Síntese de 4- e 5-arilprolinas através da reação de Heck-Matsuda e sua utilização como organocatalisadores em reações aldólicas e Mannich multicomponente: Synthesis of 4- and 5-aryl prolines via Heck-Matsuda reaction and their use as organocatalysts in aldol reaction and multicomponent Mannich.” 2010. Thesis, Universidade Estadual de Campinas. Accessed September 22, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249880.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Godoi, Marla Narciso. “Síntese de 4- e 5-arilprolinas através da reação de Heck-Matsuda e sua utilização como organocatalisadores em reações aldólicas e Mannich multicomponente: Synthesis of 4- and 5-aryl prolines via Heck-Matsuda reaction and their use as organocatalysts in aldol reaction and multicomponent Mannich.” 2010. Web. 22 Sep 2020.

Vancouver:

Godoi MN. Síntese de 4- e 5-arilprolinas através da reação de Heck-Matsuda e sua utilização como organocatalisadores em reações aldólicas e Mannich multicomponente: Synthesis of 4- and 5-aryl prolines via Heck-Matsuda reaction and their use as organocatalysts in aldol reaction and multicomponent Mannich. [Internet] [Thesis]. Universidade Estadual de Campinas; 2010. [cited 2020 Sep 22]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/249880.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Godoi MN. Síntese de 4- e 5-arilprolinas através da reação de Heck-Matsuda e sua utilização como organocatalisadores em reações aldólicas e Mannich multicomponente: Synthesis of 4- and 5-aryl prolines via Heck-Matsuda reaction and their use as organocatalysts in aldol reaction and multicomponent Mannich. [Thesis]. Universidade Estadual de Campinas; 2010. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/249880

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Universidade Estadual de Campinas

2. Miranda, Karen Fabiane Canto. Estudo da reação de Heck de anidridos maleicos com sais de arenodiazônio e suas aplicações sintéticas: Study of the Heck reaction of maleic anhydrides with arenediazonium salts and their synthetic applications.

Degree: 2010, Universidade Estadual de Campinas

Abstract: Chapter one of this work deals with methodological studies of the Heck reaction with maleic anhydride using several arenediazonium salts. Several reaction conditions were investigated and at first, it was possible by the use of palladium acetate as catalyst, to prepare a series of mono and diarylated maleic anhydrides through reaction with diazonium salts bearing electron donating groups. The reactions using diazonium salts bearing electron withdrawing groups were also investigated although, with the previous catalytic system used, the correspondent substituted maleic anhydrides weren¿t obtained. The use of POPd catalyst solved the problematic use of diazonium salts bearing electron withdrawing groups. In this way, it was possible to prepare a series of mono and diarylated maleic anhydrides, with different electron demanding conditions and substitution patterns, with satisfactory yields. Besides this, it was possible to prepare symmetric and non-symmetric bi-substituted maleic anhydrides too. Several of this maleic anhydrides prepared displayed fluorescence. Chapter two presents applications of the methodology developed in chapter one. The synthesis of marine alkaloid Polycitrin A is presented through a short synthetic route which has as key steps two consecutive Heck reactions with maleic anhydride using diazonium salt. Efforts towards total synthesis of alkaloid Polycitrin B as well as its formal synthesis are also shown in this chapter Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Correia, Carlos Roque Duarte, 1953- (advisor), Universidade Estadual de Campinas. Instituto de Química (institution), Programa de Pós-Graduação em Ciências (nameofprogram), Merlo, Aloir Antonio (committee member), Corrêa, Arlene Gonçalves (committee member), Baptistella, Lucia Helena Brito (committee member), Almeida, Wand Pereira (committee member).

Subjects/Keywords: Reação de Heck; Anidrido maleico; Sais de arenodiazônio; Heck reaction; Maleic anhydride; Arenediazonium salts

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Miranda, K. F. C. (2010). Estudo da reação de Heck de anidridos maleicos com sais de arenodiazônio e suas aplicações sintéticas: Study of the Heck reaction of maleic anhydrides with arenediazonium salts and their synthetic applications. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/249881

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Miranda, Karen Fabiane Canto. “Estudo da reação de Heck de anidridos maleicos com sais de arenodiazônio e suas aplicações sintéticas: Study of the Heck reaction of maleic anhydrides with arenediazonium salts and their synthetic applications.” 2010. Thesis, Universidade Estadual de Campinas. Accessed September 22, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249881.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Miranda, Karen Fabiane Canto. “Estudo da reação de Heck de anidridos maleicos com sais de arenodiazônio e suas aplicações sintéticas: Study of the Heck reaction of maleic anhydrides with arenediazonium salts and their synthetic applications.” 2010. Web. 22 Sep 2020.

Vancouver:

Miranda KFC. Estudo da reação de Heck de anidridos maleicos com sais de arenodiazônio e suas aplicações sintéticas: Study of the Heck reaction of maleic anhydrides with arenediazonium salts and their synthetic applications. [Internet] [Thesis]. Universidade Estadual de Campinas; 2010. [cited 2020 Sep 22]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/249881.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Miranda KFC. Estudo da reação de Heck de anidridos maleicos com sais de arenodiazônio e suas aplicações sintéticas: Study of the Heck reaction of maleic anhydrides with arenediazonium salts and their synthetic applications. [Thesis]. Universidade Estadual de Campinas; 2010. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/249881

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.