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You searched for +publisher:"Universidade Estadual de Campinas" +contributor:("Balthazar, Marcio Luiz Figueredo, 1975-"). Showing records 1 – 3 of 3 total matches.

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Universidade Estadual de Campinas

1. Lopes, Tátila Martins, 1985-. Avaliação de linguagem em epilepsia de lobo temporal mesial = correlações com neuroimagem estrutural e funcional = Language assessment in mesial temporal lobe epilepsy: correlations with structural and functional neuroimaging: Language assessment in mesial temporal lobe epilepsy : correlations with structural and functional neuroimaging.

Degree: 2017, Universidade Estadual de Campinas

Abstract: Temporal lobe epilepsy is the most common type of epilepsy in adults and is also associated with cognitive comorbidities, such as memory and language impairments, especially in temporal lobe epilepsy (TLE). In this population, a higher incidence of people with atypical language lateralization (ALL) is expected; 20% against 5% of the healthy people. Some factors are pointed as predictors: manual dominance, left-hand familial history, as well as early insult and left hemisphere lesion. Language in these patients has been studied for decades. Lately functional magnetic resonance (fMRI) technique has been replacing the WADA test and has provided new methods and paradigms to study this function in vivo, including in healthy volunteers. Therefore, the objective of this study was to delineate the language aspects in TLE with left (LHA) and right (RHA) hippocampal atrophy and patients without hippocampal atrophy (nonAH), comparing them to controls. The results were set out in two manuscripts. The first, showed the translation of a well-established language fMRI paradigm based on semantic decision and comparison of two versions: easy and complex task in 24 healthy subjects. Both versions were effective, but the complex version produced more robust results for the evaluation of the language in our patients. Therefore, complex version was chosen to conduct the study with TLE patients. The second result was presented in the manuscript which compared patients with RHA (n=31), LHA (n=32), nonHA (n=30) and controls (n=101). In this paper analyzes were performed to investigate the impact of HA on language to obtain a profile of the language in different subtypes of TLE. Analyzes were conducted to acquire the incidence of language lateralization, predictive factors and correlation with fMRI activation pattern in regions associated with language; comparison between groups regarding language activation pattern and functional connectivity, as well as a comparison of performance on the Boston naming test and its correlation with the task activation pattern. The results pointed to a similar frequency of ALL in all groups and only manual dominance as a predictor of hemispheric dominance for language. However, each group was different according to the specific regions of interest. Language activation pattern and ROI-to-ROI analysis showed that LHA presented reduced activation compared with controls and nonHA groups. Seed-based-voxel analysis showed that all groups of patients had reduced functional connectivity in relation to controls, as well as differences among patients. The higher scores on naming performance was correlated with greater activation in language areas only in RHA and nonHA groups. We concluded that patients with LHA presented worse performance in naming, activation and functional connectivity, followed by RHA, and nonHA patients were more similar to controls. This thesis shows that despite of several language fMRI studies, further investigations using different methodologies and paradigms are necessary for better… Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Cendes, Fernando, 1962- (advisor), Balthazar, Marcio Luiz Figueredo, 1975- (coadvisor), Universidade Estadual de Campinas. Faculdade de Ciências Médicas (institution), Programa de Pós-Graduação em Fisiopatologia Médica (nameofprogram), Amaro Junior, Edson (committee member), Rosset, Sara Regina Escorsi (committee member), Damasceno, Alfredo (committee member).

Subjects/Keywords: Linguagem; Imagem por ressônancia magnética; Epilepsia; Languag; Magnetic resonance imaging; Epilepsy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Lopes, Tátila Martins, 1. (2017). Avaliação de linguagem em epilepsia de lobo temporal mesial = correlações com neuroimagem estrutural e funcional = Language assessment in mesial temporal lobe epilepsy: correlations with structural and functional neuroimaging: Language assessment in mesial temporal lobe epilepsy : correlations with structural and functional neuroimaging. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/321824

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Lopes, Tátila Martins, 1985-. “Avaliação de linguagem em epilepsia de lobo temporal mesial = correlações com neuroimagem estrutural e funcional = Language assessment in mesial temporal lobe epilepsy: correlations with structural and functional neuroimaging: Language assessment in mesial temporal lobe epilepsy : correlations with structural and functional neuroimaging.” 2017. Thesis, Universidade Estadual de Campinas. Accessed September 25, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/321824.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Lopes, Tátila Martins, 1985-. “Avaliação de linguagem em epilepsia de lobo temporal mesial = correlações com neuroimagem estrutural e funcional = Language assessment in mesial temporal lobe epilepsy: correlations with structural and functional neuroimaging: Language assessment in mesial temporal lobe epilepsy : correlations with structural and functional neuroimaging.” 2017. Web. 25 Sep 2020.

Vancouver:

Lopes, Tátila Martins 1. Avaliação de linguagem em epilepsia de lobo temporal mesial = correlações com neuroimagem estrutural e funcional = Language assessment in mesial temporal lobe epilepsy: correlations with structural and functional neuroimaging: Language assessment in mesial temporal lobe epilepsy : correlations with structural and functional neuroimaging. [Internet] [Thesis]. Universidade Estadual de Campinas; 2017. [cited 2020 Sep 25]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/321824.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lopes, Tátila Martins 1. Avaliação de linguagem em epilepsia de lobo temporal mesial = correlações com neuroimagem estrutural e funcional = Language assessment in mesial temporal lobe epilepsy: correlations with structural and functional neuroimaging: Language assessment in mesial temporal lobe epilepsy : correlations with structural and functional neuroimaging. [Thesis]. Universidade Estadual de Campinas; 2017. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/321824

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Universidade Estadual de Campinas

2. Weiler, Marina, 1983-. Avaliação por ressonância magnética das conectividades funcional e estrutural das redes neurofuncionais na demência da doença de Alzheimer leve e comprometimento cognitivo leve amnéstico = Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects: Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects.

Degree: 2015, Universidade Estadual de Campinas

Abstract: Alzheimer¿s (AD) is a neurodegenerative disease that presents with cognitive, neuropsychiatric and functional alterations. Recent studies in the neuroimaging field of AD have shown that the alterations observed in these patients are not limited to specific anatomic structures (as shown in chapter 2) but also compromise neurofunctional networks, which can lead to memory and executive function impairment, among others. Due to the structural alterations such as atrophy, burden of amyloid beta and hyperphosphorilated tau, and metabolism reduction presented in its regions, the Default Mode Network (DMN) has become the most studied network in the AD field. Thus, the main objective of this thesis was to evaluate the functional and structural connectivities of the neurofunctional networks in AD ¿ emphasizing the DMN, and the relationship with cognition. Besides that, we have also studied some other anatomical aspects in AD, such as alterations in white and grey matter. In Chapter 1, we have shown that the alterations caused by the disease also affect subcortical areas such as the thalamus and the corpus callosum, which correlates to the cognitive deficit of the patients. In another exploratory study (Chapter 6), we observed that as the disease progressed, the alterations in white matter occurred were more extensive than expected, considering the structural alterations of the grey matter. Our results suggest that damage in white matter can occur independently of grey matter damage. In this context, Chapter 8 brings molecular and imaging results that reinforce the hypothesis that neurodegenerative diseases affect specific neurofunctional networks, and the propagation of altered proteins occur through white matter tracts (along DMN tracts). Keeping this in mind, in Chapter 4 we had as a main objective to isolate only the DMN tracts, in order to evaluate its structural connectivity in AD. Indeed, we observed that structural microalterations are present in DMN tracts of AD patients, contributing to their cognitive deficits. In Chapter 5, we not only investigated the functional connectivity of DMN regions, but also the amplitude of low frequency fluctuations (ALFF) of the blood oxygenation level signal of these regions. We found that amnestic mild cognitive impairment subjects (aMCI ¿ subjects at risk for developing AD) for instance, have decreased ALFF in specific regions of the DMN, though not presenting alterations in functional connectivity. AD patients, however, present both reduced ALFF and connectivity in the DMN regions. Interestingly, ALFF values did not correlate with the cognitive impairment of the patients; but connectivity values did. In Chapter 3, we have shown that other networks such as the Language and Executive Functions are also altered in AD. The functional connectivity of the DMN, in turn, correlated with episodic memory function. In Chapter 7, our main objective was to explore some other hypothesis involving the DMN function. Here, we mentioned the alterations in the self presented in AD patients… Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Balthazar, Marcio Luiz Figueredo, 1975- (advisor), Universidade Estadual de Campinas. Faculdade de Ciências Médicas (institution), Programa de Pós-Graduação em Ciências Médicas (nameofprogram), Sato, João Ricardo (committee member), Junior, Edson Amaro (committee member), Junior, Marcondes Cavalcante França (committee member), Stella, Florindo (committee member).

Subjects/Keywords: Alzheimer, Doença de; Comprometimento cognitivo leve; Rede nervosa; Imagem por ressônancia magnética; Neuroimagem funcional; Alzheimer's disease; Mild cognitive impairment; Nerve net; Magnetic resonance imaging; Functional neuroimaging

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Weiler, Marina, 1. (2015). Avaliação por ressonância magnética das conectividades funcional e estrutural das redes neurofuncionais na demência da doença de Alzheimer leve e comprometimento cognitivo leve amnéstico = Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects: Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/312858

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Weiler, Marina, 1983-. “Avaliação por ressonância magnética das conectividades funcional e estrutural das redes neurofuncionais na demência da doença de Alzheimer leve e comprometimento cognitivo leve amnéstico = Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects: Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects.” 2015. Thesis, Universidade Estadual de Campinas. Accessed September 25, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312858.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Weiler, Marina, 1983-. “Avaliação por ressonância magnética das conectividades funcional e estrutural das redes neurofuncionais na demência da doença de Alzheimer leve e comprometimento cognitivo leve amnéstico = Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects: Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects.” 2015. Web. 25 Sep 2020.

Vancouver:

Weiler, Marina 1. Avaliação por ressonância magnética das conectividades funcional e estrutural das redes neurofuncionais na demência da doença de Alzheimer leve e comprometimento cognitivo leve amnéstico = Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects: Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects. [Internet] [Thesis]. Universidade Estadual de Campinas; 2015. [cited 2020 Sep 25]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/312858.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Weiler, Marina 1. Avaliação por ressonância magnética das conectividades funcional e estrutural das redes neurofuncionais na demência da doença de Alzheimer leve e comprometimento cognitivo leve amnéstico = Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects: Evaluation by magnetic resonance imaging of functional and structural connectivities of neurofunctional networks in mild Alzheimer's disease dementia and amnestic mild cognitive impairment subjects. [Thesis]. Universidade Estadual de Campinas; 2015. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/312858

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Teixeira, Camila Vieira Ligo, 1981-. Treinamento multifuncional em sujeitos com comprometimento cognitivo leve amnéstico com evidência fisiopatológica da doença de Alzheimer = efeitos em parâmetros clínicos e de neuroimagem funcional e estrutural: Multifunctional training on subjects with amnestic mild cognitive impairment due to AD : effects on clinical parameters and functional and structural neuroimaging.

Degree: 2018, Universidade Estadual de Campinas

Abstract: Amnestic Mild Cognitive Impairment (aMCI) is a clinical term applied to patients with memory decline but with normal social functional performance. These patients are more likely to develop the dementia in Alzheimer's disease (AD), in which there is a dependency on daily lining activities. There are molecular markers found in cerebrospinal fluid (CSF), such as amyloid- beta peptide (Aß1-42) and total tau and phosphorylated tau proteins that, when altered, show that the subject has pathophysiology of AD and a higher chance of developing dementia. The practice of aerobic and resistance exercises demonstrated to be effective improving the cognitive and socio-functional performance in elders. Another type of exercise is multicomponent (MEP), which involves several physical capabilities in one program. There is a positive relationship between physical exercise and brain in elders, but the literature showing physical exercise efficacy in elderly CCL patients with a pathophysiology of AD is scarce. Thus, the main objective of the present thesis was to evaluate the effects of 12 months of a multicomponent exercise program in episodic memory, daily life activities and brain structure and connectivity of elderly with aMCI due to AD. Besides that, we analyzed possible relation between brain structure integrity and aerobic fitness in those subjects. Three studies were carried out. In all, the subjects studied were old adults diagnosed with aMCI due to AD, that is, they presented alterations, at least, in the concentration of peptide beta-amyloid and/or in the ratio Aß1-42/ptau analyzed in the CSF. In the first study, we observed relationship between aerobic fitness and gray matter of frontal areas and also positive relationship with various white matter tracts that connect the frontal, temporal and parietal regions. In studies 2 and 3, we analyzed the effect of the MEP intervention. Study 2 showed that in addition to an improvement in aerobic fitness and memory, the left and right hippocampus volume of the elderly who practiced MEP for 6 months also increased, while the group that did not practice showed worsening in functional activities and memory. Study 3 showed that 12 months of MEP practice significantly increased aerobic fitness, memory and performance in social-functional activity of its practitioners, but without changes in Default mode network connectivity. Our results suggest that aerobic fitness is positively related to the frontal cortex and white matter tracts that connect frontal, parietal and temporal areas. In addition, MEP training not only contributed to an improvement in aerobic fitness, memory performance and functionality, but also had a positive influence on the hippocampi volume of elders with aMCI due to AD Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Balthazar, Marcio Luiz Figueredo, 1975- (advisor), Universidade Estadual de Campinas. Faculdade de Ciências Médicas (institution), Programa de Pós-Graduação em Ciências Médicas (nameofprogram), Vale, Franscisco de Assis Carvalho do (committee member), Fontes, Eduardo Bodnariuc (committee member), Uchida, Marco Carlos (committee member), Fattori, André (committee member).

Subjects/Keywords: Comprometimento cognitivo leve; Exercícios físicos; Cognição; Cérebro; Mild cognitive impairment; Physical exercise; Cognition; Brain

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Teixeira, Camila Vieira Ligo, 1. (2018). Treinamento multifuncional em sujeitos com comprometimento cognitivo leve amnéstico com evidência fisiopatológica da doença de Alzheimer = efeitos em parâmetros clínicos e de neuroimagem funcional e estrutural: Multifunctional training on subjects with amnestic mild cognitive impairment due to AD : effects on clinical parameters and functional and structural neuroimaging. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/331120

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Teixeira, Camila Vieira Ligo, 1981-. “Treinamento multifuncional em sujeitos com comprometimento cognitivo leve amnéstico com evidência fisiopatológica da doença de Alzheimer = efeitos em parâmetros clínicos e de neuroimagem funcional e estrutural: Multifunctional training on subjects with amnestic mild cognitive impairment due to AD : effects on clinical parameters and functional and structural neuroimaging.” 2018. Thesis, Universidade Estadual de Campinas. Accessed September 25, 2020. http://repositorio.unicamp.br/jspui/handle/REPOSIP/331120.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Teixeira, Camila Vieira Ligo, 1981-. “Treinamento multifuncional em sujeitos com comprometimento cognitivo leve amnéstico com evidência fisiopatológica da doença de Alzheimer = efeitos em parâmetros clínicos e de neuroimagem funcional e estrutural: Multifunctional training on subjects with amnestic mild cognitive impairment due to AD : effects on clinical parameters and functional and structural neuroimaging.” 2018. Web. 25 Sep 2020.

Vancouver:

Teixeira, Camila Vieira Ligo 1. Treinamento multifuncional em sujeitos com comprometimento cognitivo leve amnéstico com evidência fisiopatológica da doença de Alzheimer = efeitos em parâmetros clínicos e de neuroimagem funcional e estrutural: Multifunctional training on subjects with amnestic mild cognitive impairment due to AD : effects on clinical parameters and functional and structural neuroimaging. [Internet] [Thesis]. Universidade Estadual de Campinas; 2018. [cited 2020 Sep 25]. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/331120.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Teixeira, Camila Vieira Ligo 1. Treinamento multifuncional em sujeitos com comprometimento cognitivo leve amnéstico com evidência fisiopatológica da doença de Alzheimer = efeitos em parâmetros clínicos e de neuroimagem funcional e estrutural: Multifunctional training on subjects with amnestic mild cognitive impairment due to AD : effects on clinical parameters and functional and structural neuroimaging. [Thesis]. Universidade Estadual de Campinas; 2018. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/331120

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.