+publisher:"Texas A&M University" +contributor:("Gill, Clare")

Texas A&M University

1. Cilkiz, Kubra. Genome-Wide Association Study of the Woody Breast Myopathy in Broiler Chickens.

Degree: MS, Animal Science, 2018, Texas A&M University

URL: http://hdl.handle.net/1969.1/174113

► Increasing demand for poultry meat has encouraged production of the maximum possible yield from chicken, which resulted in broiler chickens being subjected to intense selection… (more)

▼ Increasing demand for poultry meat has encouraged production of the maximum possible yield from chicken, which resulted in broiler chickens being subjected to intense selection for increased Pectoralis major (P. major) breast muscle yield and growth rate. That is presumed to contribute to development of new myopathies, which mainly impairs the nutritional value of the meat and meat quality, and in turn, affects consumer acceptance. A recent and prominent example is woody breast (WB) myopathy characterized by palpably tough breast muscle, which imposes an additional economic burden on the poultry industry. The basis of WB myopathy is not known yet but is suspected to be genetic due to its association with growth rate. Development of the WB myopathy is tightly linked to growth rate, which is under intense selection. On the other hand, growth rate and body mass are complex traits, and WB myopathy is associated with growth rate, which suggests that WB myopathy is more likely a complex trait. Genome-wide association studies (GWAS), which have become more feasible with recent improvements in high-throughput genotyping technologies, were exploited with the aim of the investigating the underlying etiology and genetic mechanism of woody breast myopathy. Using 600 K HD Affymetrix Axiom Array, 10 affected broilers and 10 healthy White Plymouth Rocks (WPR) were genotyped. SNPs and constructed haplotype blocks were examined whether they exhibited statistically significant association with woody breast myopathy. The current study conducted by SNPs and haplotypes suggested that several biological pathways and genes associated with oxidative stress, Ca2+ binding, microtubule motor activity and cellular repair could be contributing factors regarding the onset of woody breast myopathy. However, analysis of results clearly showed that the sample introduced biases related to selection of study participants into the association analysis. Due to small sample size, after correcting for population stratification, it was not possible to detect true disease variants or genes genuinely affecting woody breast myopathy. Advisors/Committee Members: Riley, David G (advisor), Athrey, Giridhar (advisor), Gill, Clare (committee member).

Subjects/Keywords: Woody Breast; GWAS

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APA (6^th Edition):

Cilkiz, K. (2018). Genome-Wide Association Study of the Woody Breast Myopathy in Broiler Chickens. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/174113

Chicago Manual of Style (16^th Edition):

Cilkiz, Kubra. “Genome-Wide Association Study of the Woody Breast Myopathy in Broiler Chickens.” 2018. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/174113.

MLA Handbook (7^th Edition):

Cilkiz, Kubra. “Genome-Wide Association Study of the Woody Breast Myopathy in Broiler Chickens.” 2018. Web. 17 Jan 2021.

Vancouver:

Cilkiz K. Genome-Wide Association Study of the Woody Breast Myopathy in Broiler Chickens. [Internet] [Masters thesis]. Texas A&M University; 2018. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/174113.

Council of Science Editors:

Cilkiz K. Genome-Wide Association Study of the Woody Breast Myopathy in Broiler Chickens. [Masters Thesis]. Texas A&M University; 2018. Available from: http://hdl.handle.net/1969.1/174113

Texas A&M University

2. Sarlo, Kaitlyn Mary. Reciprocal Differences in F2 and F3 Nellore-Angus Halfblood Steers for Growth and Health Traits.

Degree: MS, Animal Breeding, 2016, Texas A&M University

URL: http://hdl.handle.net/1969.1/157732

► Nellore-Angus halfblood reciprocal F2 and F3 steers (n = 372) produced in the Texas A&M AgriLife Research McGregor Genomics project were evaluated for weight and… (more)

▼ Nellore-Angus halfblood reciprocal F2 and F3 steers (n = 372) produced in the Texas A&M AgriLife Research McGregor Genomics project were evaluated for weight and growth through different stages of life, including after a standardized bovine viral diarrhea virus (BVDV) challenge. The F2 steers were sired by F1 Nellore-sired (NA) or Angus-sired (AN) bulls out of F1 NA and AN dams (4 reciprocal calf types of ANAN, ANNA, NAAN, NANA, where the breed type of the bull is listed first). The F3 steers resulted from F2 NANA parents. There were no differences due to calf type for birth weight. From birth to weaning the F3 steers gained between 0.10 and 0.13 kg less (P < 0.05) per d than the F2 steers. The F3 steers were lighter than all F2 calf types at weaning, a year of age, through a 42-d health trial, and 15 mo of age. The NAAN steers were the heaviest (P < 0.05) calf type for weaning weight, yearling weight and weight at 15 mo. During the 42-d health and feeding trial, weights of F2 steers out of AN dams were 7 to 10 kg heavier (P < 0.05) than F2 steers out of NA dams. A similar pattern existed for ADG; ADG of the F3 steers was not significantly different from F2 steers out of NA dams. The F2 steers out of AN dams also had higher (P < 0.05) monocyte counts than F2 steers out of NA dams. Although monocyte count was not correlated to ADG during the 42-d health trial, it was lowly and positively correlated (r = 0.14, P = 0.008) with ADG from weaning to a year of age. Different patterns of relationship were present stages among the different calf types. For the NANA (r = -0.52, P = 0.003), F3 (r = -0.22, P = 0.003) and NAAN (r= -0.20, P = 0.003) steers there was a negative correlation of rectal temperature change and ADG from d 0 to 14 post challenge. Rectal temperature change post BVDV challenge was positively correlated with ADG from weaning to yearling weight for NANA (r = 0.62, P = 0.002) and ANNA (r = 0.28, P = 0.026) steers. Only ANAN steers had a relationship of preweaning ADG with rectal temperature change from BVDV challenge (r = 0.43, P = 0.046). In these cattle, the apparent trade-offs between growth and health responses appear inconsistent. The nature and interpretations of these reciprocal differences remain unclear and warrant additional research. Advisors/Committee Members: Herring, Andy D (advisor), Riley, David G (committee member), Gill, Clare A (committee member).

Subjects/Keywords: Nellore; Angus; reciprocal difference

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APA (6^th Edition):

Sarlo, K. M. (2016). Reciprocal Differences in F2 and F3 Nellore-Angus Halfblood Steers for Growth and Health Traits. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/157732

Chicago Manual of Style (16^th Edition):

Sarlo, Kaitlyn Mary. “Reciprocal Differences in F2 and F3 Nellore-Angus Halfblood Steers for Growth and Health Traits.” 2016. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/157732.

MLA Handbook (7^th Edition):

Sarlo, Kaitlyn Mary. “Reciprocal Differences in F2 and F3 Nellore-Angus Halfblood Steers for Growth and Health Traits.” 2016. Web. 17 Jan 2021.

Vancouver:

Sarlo KM. Reciprocal Differences in F2 and F3 Nellore-Angus Halfblood Steers for Growth and Health Traits. [Internet] [Masters thesis]. Texas A&M University; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/157732.

Council of Science Editors:

Sarlo KM. Reciprocal Differences in F2 and F3 Nellore-Angus Halfblood Steers for Growth and Health Traits. [Masters Thesis]. Texas A&M University; 2016. Available from: http://hdl.handle.net/1969.1/157732

Texas A&M University

3. Prause, Macee Robyn. Analysis of Methylation Patterns in Ejaculated Sperm from F1 Nellore-Angus Crossbred Bulls.

Degree: MS, Animal Science, 2016, Texas A&M University

URL: http://hdl.handle.net/1969.1/159098

► Methylation of the carbon 5 position of cytosine is a common epigenetic mark in vertebrates, and has been associated with male infertility. Methylation can be… (more)

Subjects/Keywords: Epigenetics; DNA Methylation; Cytosine; Bovine; Sperm

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APA (6^th Edition):

Prause, M. R. (2016). Analysis of Methylation Patterns in Ejaculated Sperm from F1 Nellore-Angus Crossbred Bulls. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/159098

Chicago Manual of Style (16^th Edition):

Prause, Macee Robyn. “Analysis of Methylation Patterns in Ejaculated Sperm from F1 Nellore-Angus Crossbred Bulls.” 2016. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/159098.

MLA Handbook (7^th Edition):

Prause, Macee Robyn. “Analysis of Methylation Patterns in Ejaculated Sperm from F1 Nellore-Angus Crossbred Bulls.” 2016. Web. 17 Jan 2021.

Vancouver:

Prause MR. Analysis of Methylation Patterns in Ejaculated Sperm from F1 Nellore-Angus Crossbred Bulls. [Internet] [Masters thesis]. Texas A&M University; 2016. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/159098.

Council of Science Editors:

Prause MR. Analysis of Methylation Patterns in Ejaculated Sperm from F1 Nellore-Angus Crossbred Bulls. [Masters Thesis]. Texas A&M University; 2016. Available from: http://hdl.handle.net/1969.1/159098

Texas A&M University

4. Vitanza, Sarah M. Expression of Candidate Genes for Horn Growth in Early Bovine Development.

Degree: MS, Animal Science, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7604

► Bovine horns develop primarily after birth and the presence or absence of horns is due to a single gene. It has been reported that the… (more)

▼ Bovine horns develop primarily after birth and the presence or absence of horns is due to a single gene. It has been reported that the horn bud appears in the bovine embryo at d 60 of gestation. Our hypothesis is that the gene that determines the presence of horns is expressed in osteoprogenitor cells of the early fetus and will affect the expression of RUNX2, MSX1, MSX2, and/or TWIST1. To test this hypothesis, bovine fetal samples were collected from commercial females at the Caviness Packing Company in Hereford, Texas. Fetuses ranged from d 28 to d 80 of gestation. A survey of the expression of genes from the region on bovine chromosome 1 known to contain the locus that causes horns (IFNAR1 to SOD1), was conducted using qualitative and quantitative RT-PCR, and in situ hybridization. Genes with known roles in osteogenesis and chrondrogenesis (MSX1, TWIST1, RUNX2 and SOX9) were included as positive controls. With the exception of OLIG1, which was only expressed in the brain, all of the genes investigated were expressed in fetal frontal and parietal bones by qualitative RT-PCR. The level of expression of C21orf59, C21orf66, IL10RB, and SFRS15 increased in the frontal bone of horned samples from d 55 to d 70 of gestation. At d 60 of gestation, a change in the shape of the frontal bone was observed, which has been reported to be the developmental stage when the horn bud appears. At this time point, MSX1, TWIST1, RUNX2 and SOX9 were detected in frontal bone, in cells from the osteoblast lineage, as expected. Furthermore, C21orf59, C21orf62, C21or66 and SFRS15 from the polled interval were localized to developing mesenchyme, osteoblasts and/or osteoclasts of the frontal bone, suggesting that each of these genes has a role in intramembranous bone formation. In addition, gradients of expressed C21orf66 and SFRS15 were detected in developing endochondral bone. There was evidence of an antisense transcript of C21orf66 expressed in the same cell types as the sense transcript. Further characterization of this antisense transcript demonstrated that it covered the entire sense transcript. Based on observed expression in the mesenchyme, rather than just in mature osteoblasts or osteoclasts, C21orf66 and/or its antisense transcript become the most likely candidates for the polled locus. Advisors/Committee Members: Gill, Clare A. (advisor), Riggs, Penny K. (advisor), Sanders, James O. (committee member).

Subjects/Keywords: Bovine; Horns; Polled; Intramembranous bone; Fetal development

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APA (6^th Edition):

Vitanza, S. M. (2011). Expression of Candidate Genes for Horn Growth in Early Bovine Development. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7604

Chicago Manual of Style (16^th Edition):

Vitanza, Sarah M. “Expression of Candidate Genes for Horn Growth in Early Bovine Development.” 2011. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7604.

MLA Handbook (7^th Edition):

Vitanza, Sarah M. “Expression of Candidate Genes for Horn Growth in Early Bovine Development.” 2011. Web. 17 Jan 2021.

Vancouver:

Vitanza SM. Expression of Candidate Genes for Horn Growth in Early Bovine Development. [Internet] [Masters thesis]. Texas A&M University; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7604.

Council of Science Editors:

Vitanza SM. Expression of Candidate Genes for Horn Growth in Early Bovine Development. [Masters Thesis]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2009-12-7604

Texas A&M University

5. Scienski, Kathy. Characterizing a Region of Bovine Chromosome 6 Associated with Three Cattle Coat Color Phenotypes.

Degree: MS, Genetics, 2018, Texas A&M University

URL: http://hdl.handle.net/1969.1/174087

► Coat color of mammals, especially mice, has been a valuable model for the study of adaptation, pleiotropy, and gene action and interactions. More recently, however,… (more)

▼ Coat color of mammals, especially mice, has been a valuable model for the study of adaptation, pleiotropy, and gene action and interactions. More recently, however, the characterization of coat color in livestock has begun to identify genes associated with and causing different coat color phenotypes. Color is an especially important attribute in livestock as it is often a required component of breed recognition and registration. There are also numerous point-of-sale marketing programs designed to offer economic premiums for certain colors. Pigmentation in purebred cattle typically follows a pattern of Mendelian inheritance, but crossbred cattle often produce colors that are atypical of purebred cows. The aim of this study was to characterize a region on bovine chromosome 6 previously associated with three cattle coat color phenotypes in a population of Nellore-Angus crossbred cattle: gray, reddening, and white spotting. Genome-wide association studies (GWAS) were performed for the gray and spotting phenotypes using high-density SNP genotypes, and the regions associated with all three phenotypes were fine mapped. GWAS identified the same genes associated with gray and spotting phenotypes found in previous studies—CORIN and KIT, respectively. Fine mapping revealed that the E+E+ genotype at MC1R coupled with a mutation within CORIN was coincident with the gray phenotype, although later findings suggest that these factors are necessary but not sufficient for gray. A missense variant in CHIC2 was identified in the whole-genome sequenced founders contributing to EDE+ red animals. Additionally, founder data indicated that KIT and the region associated with white spotting lies within a poorly assembled region of the bovine genome. Haplotype breed of origin also tends to influence all three phenotypes. Histological examinations of skin and hair revealed that gray coat color in this population results when white hair occurs atop dark-pigmented skin, and that lack of hair pigmentation is due to both melanocyte depletion and displacement. Advisors/Committee Members: Gill, Clare (advisor), Riggs, Penny (committee member), Riley, David (committee member), Stelly, David (committee member).

Subjects/Keywords: coat color; Nellore-Angus; BTA 6

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APA (6^th Edition):

Scienski, K. (2018). Characterizing a Region of Bovine Chromosome 6 Associated with Three Cattle Coat Color Phenotypes. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/174087

Chicago Manual of Style (16^th Edition):

Scienski, Kathy. “Characterizing a Region of Bovine Chromosome 6 Associated with Three Cattle Coat Color Phenotypes.” 2018. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/174087.

MLA Handbook (7^th Edition):

Scienski, Kathy. “Characterizing a Region of Bovine Chromosome 6 Associated with Three Cattle Coat Color Phenotypes.” 2018. Web. 17 Jan 2021.

Vancouver:

Scienski K. Characterizing a Region of Bovine Chromosome 6 Associated with Three Cattle Coat Color Phenotypes. [Internet] [Masters thesis]. Texas A&M University; 2018. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/174087.

Council of Science Editors:

Scienski K. Characterizing a Region of Bovine Chromosome 6 Associated with Three Cattle Coat Color Phenotypes. [Masters Thesis]. Texas A&M University; 2018. Available from: http://hdl.handle.net/1969.1/174087

Texas A&M University

6. Holland, Paul Wesley. Estimation of Genetic Parameters Associated with Ewe Reproductive Life and Lamb Mortality in Northwestern United States Sheep.

Degree: PhD, Animal Breeding, 2018, Texas A&M University

URL: http://hdl.handle.net/1969.1/174032

► Ewe reproductive life traits such as longevity and stayability (the probability that a ewe will avoid removal from the flock due to reproductive performance or… (more)

▼ Ewe reproductive life traits such as longevity and stayability (the probability that a ewe will avoid removal from the flock due to reproductive performance or health) are economically important because of the relationship of removal rates with the value of the cull ewe and cost of replacements. Ewe reproductive life was evaluated as: 1) ewe longevity, 2) ewe stayability to six different ages, and 3) ewe survival. The litter size of a ewe at her birth and her litter size at rearing were investigated for potential effects on these traits. Ewe litter size at rearing was not significant in any analyses (P > 0.15), but the ewe’s litter size at birth was a significant effect in most analyses. Smaller litter sizes at birth, particularly ewes born as singles, were more often associated with greater mean longevity and stayability to specific ages (P < 0.05). Ewes born as singles had survivor functions characterized by higher probability of survival to older ages (P < 0.05). Polypay ewes had lower longevity and stayability to different ages than other breeds, as well as a survival function with lower probabilities than other breeds for survival to most older ages. Genetic parameters for these measures were consistently low for longevity (estimates of heritability ranged from 0.06 ± 0.022 in the within breed analysis of Columbia to 0.16 ± 0.024 in within breed analysis of Rambouillet). Estimates of heritability for stayability in general were somewhat higher than those for ewe longevity (ranged from 0.08 ± 0.061 for stayability to 6 yr in Columbia to 0.34 ± 0.027 for stayability to 2 yr in the across breed analyses). Lamb mortality is important to the sheep industry. Mortality was evaluated as: 1) mortality due to any reason, 2) mortality associated with birth (or at birth), and 3) mortality due to pneumonia. Estimates of heritability ranged from 0.05 ± 0.022 in the analysis of overall mortality in Polypay to 0.47 ± 0.032 in the analysis of birth mortality in Polypay. Some of these estimates of heritability suggest that selection programs could be effective for these traits. Advisors/Committee Members: Riley, David G (advisor), Sanders, James O (committee member), Gill, Clare A (committee member), Herring, Andy D (committee member).

Subjects/Keywords: ewe longevity; ewe stayability; genetic parameters; lamb mortality

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APA (6^th Edition):

Holland, P. W. (2018). Estimation of Genetic Parameters Associated with Ewe Reproductive Life and Lamb Mortality in Northwestern United States Sheep. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/174032

Chicago Manual of Style (16^th Edition):

Holland, Paul Wesley. “Estimation of Genetic Parameters Associated with Ewe Reproductive Life and Lamb Mortality in Northwestern United States Sheep.” 2018. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/174032.

MLA Handbook (7^th Edition):

Holland, Paul Wesley. “Estimation of Genetic Parameters Associated with Ewe Reproductive Life and Lamb Mortality in Northwestern United States Sheep.” 2018. Web. 17 Jan 2021.

Vancouver:

Holland PW. Estimation of Genetic Parameters Associated with Ewe Reproductive Life and Lamb Mortality in Northwestern United States Sheep. [Internet] [Doctoral dissertation]. Texas A&M University; 2018. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/174032.

Council of Science Editors:

Holland PW. Estimation of Genetic Parameters Associated with Ewe Reproductive Life and Lamb Mortality in Northwestern United States Sheep. [Doctoral Dissertation]. Texas A&M University; 2018. Available from: http://hdl.handle.net/1969.1/174032

Texas A&M University

7. Muntean, Carl. Evaluation of F1 Cows Sired by Brahman, Boran, and Tuli Bulls for Reproductive and Maternal Performance Traits and Cow Longevity.

Degree: MS, Animal Breeding, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9455

► Birth (BWT) (n = 1,335) and weaning weight (WWT) (n = 1,246), pregnancy rate (PR) (n = 1,513), calf crop born (CCB) (n = 1,504),… (more)

▼ Birth (BWT) (n = 1,335) and weaning weight (WWT) (n = 1,246), pregnancy rate (PR) (n = 1,513), calf crop born (CCB) (n = 1,504), calf crop weaned (CCW) (n = 1,500), cow weight at palpation (CW) (n = 1,662), and cow body condition score (BCS) (n = 1,666) were evaluated from 1994 to 2010 in 143 F1 females sired by Brahman (B), Boran (Bo), and Tuli (T) bulls and out of Angus and Hereford cows. Mouth scores (MS) (n = 253) were assigned to the remaining cows from 2004 to 2009, excluding 2008. Pregnancy rate, CCB, CCW, CW, and BCS were evaluated using a model that consisted of sire of cow breed, dam of cow breed, and calf's birth year/age of cow as fixed effects. Cow within sire of cow within sire breed of cow and sire of cow within sire breed of cow were used as random effects. Birth weight and WWT were evaluated including sex of calf in the same model. Mouth scores were evaluated with two models. When broken and solid mouths were scored 1 and smooth 0, B- and Bo-sired cows (0.87 and 0.83) had higher scores (P < 0.05) than T-sired females (0.65). When solid mouths were scored 1 and smooth and broken scored 0, B-sired cows (0.40) were higher than T (0.07) (P < 0.05), and Bo (0.30) sired cows were not different from either (P > 0.05). The model for MS only included sire of cow breed and calf's birth year/age of cow as fixed effects. Two-way interactions were tested for significance. Calf's birth year/age of cow was important for all traits (P < 0.05) except the first MS model. Adjusted means (LSM) for BWT for calves out of cows by B, Bo, and T sires were 34.1, 34.0, and 34.1 kg respectively, and were not different from one another (P > 0.05). Least squares means for WWT for calves out of cows by B, Bo, and T sires were 236.7, 217.5, and 197.2 kg, respectively, and were significantly different. For both BWT and WWT, male calves were heavier (P < 0.05) than females, by 2.13 kg and 10.39 kg, on average. Least squares means for PR for females sired by B, Bo, and T bulls were 0.900, 0.930, and 0.912, and were not different (P > 0.05). Adjusted means for CCB for females sired by B, Bo, and T sires were 0.872, 0.944, and 0.892 respectively, and Bo was higher (P < 0.05) than B and T. Calf crop weaned ranked the same as CCB with adjusted means of 0.805, 0.894, and 0.843 for cows by B, Bo, and T bulls, with Bo being higher (P < 0.05) than B. Cow weight adjusted means for cows by B, Bo and T sires were 537.1, 468.9, and 462.6 kg, respectively, with B-sired females being heavier (P < 0.05) than both Bo and T sired cows. Body condition scores for B, Bo, and T sired cows were 5.19, 5.43, and 5.15, respectively, with Bo-sired cows being the highest (P < 0.05). Higher reproductive rates were found for Bo-sired cows, but B-sired cows weaned heavier calves. Advisors/Committee Members: Sanders, James O. (advisor), Gill, Clare A. (committee member), Herring, Andy D. (committee member), Riley, David G. (committee member).

Subjects/Keywords: Brahman; Boran; Tuli

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APA (6^th Edition):

Muntean, C. (2011). Evaluation of F1 Cows Sired by Brahman, Boran, and Tuli Bulls for Reproductive and Maternal Performance Traits and Cow Longevity. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9455

Chicago Manual of Style (16^th Edition):

Muntean, Carl. “Evaluation of F1 Cows Sired by Brahman, Boran, and Tuli Bulls for Reproductive and Maternal Performance Traits and Cow Longevity.” 2011. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9455.

MLA Handbook (7^th Edition):

Muntean, Carl. “Evaluation of F1 Cows Sired by Brahman, Boran, and Tuli Bulls for Reproductive and Maternal Performance Traits and Cow Longevity.” 2011. Web. 17 Jan 2021.

Vancouver:

Muntean C. Evaluation of F1 Cows Sired by Brahman, Boran, and Tuli Bulls for Reproductive and Maternal Performance Traits and Cow Longevity. [Internet] [Masters thesis]. Texas A&M University; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9455.

Council of Science Editors:

Muntean C. Evaluation of F1 Cows Sired by Brahman, Boran, and Tuli Bulls for Reproductive and Maternal Performance Traits and Cow Longevity. [Masters Thesis]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9455

Texas A&M University

8. Cardin, Jessica Marie. Evaluation of Gene Breed Type and Expression of Feed Efficiency Candidate Genes, and Their Associations with Carcass Traits in F2 Nellore-Angus Steers.

Degree: MS, Animal Breeding, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10123

► Steers produced in Cycle I of the Texas A & M University McGregor Genomics Project (n = 232, F2 Nellore-Angus) were evaluated for carcass composition,… (more)

▼ Steers produced in Cycle I of the Texas A & M University McGregor Genomics Project (n = 232, F2 Nellore-Angus) were evaluated for carcass composition, visceral organ weights, and model predicted residual consumption (MPRC), a measure of feed efficiency. Hot carcass weight was strongly correlated with liver weight (r = 0.70, P < 0.001) heart weight (r = 0.58, P < 0.001), and viscera weight (r = 0.55, P < 0.001) but not spleen weight (r = -0.01, P = 0.83). Liver, heart and viscera weights were moderately positively correlated with external and kidney pelvic heart fat (KPH), but not with marbling. None of the organ weights were correlated with MPRC. A subset of 54 animals was selected for extreme values of residuals of MPRC after a mixed model analysis that included fixed effects of sire and family nested within sire, and these animals were evaluated for insulin-like growth factor I (IGFI) expression in liver samples collected at harvest through quantitative real time polymerase chain reaction (qRT-PCR). IGFI relative quantity (IGFI RQ) was collected from qRT-PCR and was correlated with liver (r = -0.23, P = 0.09), spleen (r = 0.48, P <0.001) and viscera weight (r = 0.24, P = 0.08), but not any carcass trait or MPRC residual. Gene breed types were determined for 4 candidate genes of feed efficiency: insulin like growth factor-1 (IGF1), leptin (LEP), neuropeptide-Y (NPY) and ghrelin (GHRL). Gene breed types were represented as AA, AN, NA, and NN where A and N denote Angus and Nellore, respectively, and paternal inheritance is listed first. Given that contemporary group significantly influenced most traits (MPRC, all carcass traits, liver weight and viscera weight), effects of gene breed type and contemporary group were evaluated together in analyses. GHRL influenced liver (P = 0.02) and viscera weight (P = 0.02), IGF1 influenced kidney, pelvic, and heart fat (P = 0.05), NPY influenced liver weight (P = 0.03) and hot carcass weight (P = 0.04), and LEP influenced ribeye area (P = 0.05) and hot carcass weight (P = 0.04) with a tendency to influence liver weight (P = 0.06). Alternate heterozygotes for GHRL were statistically different in liver weight and viscera weight where NA was heavier than AN. Alternate heterozygotes for LEP did not differ in ribeye area, hot carcass weight, or liver weight. Alternate heterozygotes for NPY differed in liver weight (NA heavier than AN), but did not differ in hot carcass weight. Carcasses with AA for LEP and NPY were 18 to 19 kg heavier (P < 0.05) than those with NN, with heterozygotes intermediate. Advisors/Committee Members: Riggs, Penny K. (advisor), Herring, Andy D. (advisor), Sanders, James O. (committee member), Gill, Clare (committee member).

Subjects/Keywords: organ; efficiency; Angus; Nellore; carcass

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Cardin, J. M. (2011). Evaluation of Gene Breed Type and Expression of Feed Efficiency Candidate Genes, and Their Associations with Carcass Traits in F2 Nellore-Angus Steers. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10123

Chicago Manual of Style (16^th Edition):

Cardin, Jessica Marie. “Evaluation of Gene Breed Type and Expression of Feed Efficiency Candidate Genes, and Their Associations with Carcass Traits in F2 Nellore-Angus Steers.” 2011. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10123.

MLA Handbook (7^th Edition):

Cardin, Jessica Marie. “Evaluation of Gene Breed Type and Expression of Feed Efficiency Candidate Genes, and Their Associations with Carcass Traits in F2 Nellore-Angus Steers.” 2011. Web. 17 Jan 2021.

Vancouver:

Cardin JM. Evaluation of Gene Breed Type and Expression of Feed Efficiency Candidate Genes, and Their Associations with Carcass Traits in F2 Nellore-Angus Steers. [Internet] [Masters thesis]. Texas A&M University; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10123.

Council of Science Editors:

Cardin JM. Evaluation of Gene Breed Type and Expression of Feed Efficiency Candidate Genes, and Their Associations with Carcass Traits in F2 Nellore-Angus Steers. [Masters Thesis]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10123

Texas A&M University

9. Vaughn, Robert Neil. Genetic Mechanisms that Contribute to Differences in Beef Tenderness Following Electrical Stimulation.

Degree: PhD, Genetics, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/186976

► Tenderness is a key issue for consumers that is influenced by many environmental and genetic factors. Electrical stimulation (ES) is a postmortem treatment used to… (more)

▼ Tenderness is a key issue for consumers that is influenced by many environmental and genetic factors. Electrical stimulation (ES) is a postmortem treatment used to increase tenderness and reduce variation between carcasses within scientific treatment groups. The purpose of this study was to examine genetic factors that influence tenderness in response to ES. Samples were obtained from a crossbred Nellore-Angus herd produced in McGregor TX. Muscle samples were obtained immediately after slaughter, and those selected for this study were based on divergent response to ES. Tenderness was determined by objective Warner-Bratzler shear force measurements following 14 d of aging. A commercial cattle microarray was used to identify large sets of genes with significantly different gene expression between tenderness groups. These data were used to find significantly enriched genetic signaling pathways. A subset of genes based on expression and pathway analysis was selected for verification by realtime quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). A subset of gene products was selected for western blot protein expression assays. In addition SNP haplotype blocks (hapblocks) were constructed that encompassed genes of interest to determine whether parent or breed of origin for these genes contributed to ES response. The ECM and closely related focal adhesion pathways were significantly enriched from the microarray assay. From this pathway a total of 40 genes was assayed by qRT-PCR. Of the assayed genes, many integrins were significantly upregulated in the group that responded well to electrical stimulation compared to the group that responded poorly. Through hapblock analysis, it was found that breed and parent of origin played a role in many production features including efficiency and growth rates. Breed of origin of integrin alpha-6 (ITGA6) could be linked to a 0.15 kg difference in ES residual tenderness values when inherited maternally (P = 0.03). The gene FN1 had a breed of origin effect, with a difference in ES residual tenderness of 0.23 kg for different paternally-inherited hapblocks. Additionally, ITGA6 protein expression was found to closely follow mRNA expression in a subset of animals chosen for western blot analysis. These results suggest that components of the ECM may be a novel area of research for improving tenderness that will benefit both producers and consumers. Advisors/Committee Members: Riggs, Penny K (advisor), Gill, Clare A (committee member), Herring, Andy D (committee member), Smith, Stephen B (committee member).

Subjects/Keywords: Beef; tenderness; electrical stimulation; WBSF

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vaughn, R. N. (2013). Genetic Mechanisms that Contribute to Differences in Beef Tenderness Following Electrical Stimulation. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/186976

Chicago Manual of Style (16^th Edition):

Vaughn, Robert Neil. “Genetic Mechanisms that Contribute to Differences in Beef Tenderness Following Electrical Stimulation.” 2013. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/186976.

MLA Handbook (7^th Edition):

Vaughn, Robert Neil. “Genetic Mechanisms that Contribute to Differences in Beef Tenderness Following Electrical Stimulation.” 2013. Web. 17 Jan 2021.

Vancouver:

Vaughn RN. Genetic Mechanisms that Contribute to Differences in Beef Tenderness Following Electrical Stimulation. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/186976.

Council of Science Editors:

Vaughn RN. Genetic Mechanisms that Contribute to Differences in Beef Tenderness Following Electrical Stimulation. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/186976

Texas A&M University

10. Caldwell, Jana Denise. Investigation for Genetic Determinants of Flexion Contractures and Contracted Foal Syndrome in Neonatal Thoroughbred Foals.

Degree: PhD, Biomedical Sciences, 2014, Texas A&M University

URL: http://hdl.handle.net/1969.1/153856

► Musculoskeletal disorders are one of the leading causes of morality in neonatal Thoroughbred foals. Contracted Foal Syndrome (CFS) has accounted for up to 48% of… (more)

▼ Musculoskeletal disorders are one of the leading causes of morality in neonatal Thoroughbred foals. Contracted Foal Syndrome (CFS) has accounted for up to 48% of such disorders in foals submitted for necropsy according to the Kentucky Livestock Diagnostic Center and is reportedly a concern to clinicians and breeders. CFS is primarily characterized by limb contractures and other malformations of the appendicular and/or axial skeleton. Foals are often euthanized in severe cases and successful rehabilitation in moderate cases does not entirely negate secondary complications. Because of the economic implications associated with treatment costs, owners may opt to euthanize foals even though they potentially could have led productive lives. A familial predisposition was observed in some cases. In addition, veterinarians reported increased incidence of contracted foals in one particular sire line. This, coupled with model genetic disorders in other species, prompted us to conduct the first molecular genetics study on congenital flexion and CFS. The inconsistent nature of clinical documentation and variable phenotypes pose a challenge to researchers investigating such complex conditions. We therefore conducted a detailed analysis of the phenotypes and used the data to propose a preliminary classification system that could be used by clinicians and researchers. The implementation of such a classification system will reduce ambiguity of clinical documentation and provide the basis for future study designs. Our hypothesis states, that in some cases, flexion contractures and CFS are major gene disorders with the likelihood of genetic heterogeneity. Our first approach was to sequence the candidate gene, tropomyosin beta 2. This gene encodes a component of the skeletal muscle contractile apparatus and has been implicated in congenital distal limb contractures in humans. Next, new utilized the newly available Equine SNP50 Beadchip for a case/control population based genome-wide association mapping approach followed by a family validation study and family based genome-wide association study. These approaches resulted in the identification of associations between various subtypes of contracted foals and at least 3 disease susceptibility loci. In summary, this study provides insight into the genetics underlying flexion contractures and CFS in the neonatal foal and has proved the first evidence for a genetic cause. Furthermore, it provides a solid foundation for future research targeting candidate genes for resequencing. Advisors/Committee Members: Chowdhary, Bhanu P (advisor), Gill, Clare A (committee member), Raudsepp, Terje (committee member), Seabury, Christopher (committee member), Moyer, William (committee member).

Subjects/Keywords: Thoroughbred; Foal; Genetic; Musculoskeletal; Congenital; Candidate genes; sequencing; GWAS; Classification

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Caldwell, J. D. (2014). Investigation for Genetic Determinants of Flexion Contractures and Contracted Foal Syndrome in Neonatal Thoroughbred Foals. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/153856

Chicago Manual of Style (16^th Edition):

Caldwell, Jana Denise. “Investigation for Genetic Determinants of Flexion Contractures and Contracted Foal Syndrome in Neonatal Thoroughbred Foals.” 2014. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/153856.

MLA Handbook (7^th Edition):

Caldwell, Jana Denise. “Investigation for Genetic Determinants of Flexion Contractures and Contracted Foal Syndrome in Neonatal Thoroughbred Foals.” 2014. Web. 17 Jan 2021.

Vancouver:

Caldwell JD. Investigation for Genetic Determinants of Flexion Contractures and Contracted Foal Syndrome in Neonatal Thoroughbred Foals. [Internet] [Doctoral dissertation]. Texas A&M University; 2014. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/153856.

Council of Science Editors:

Caldwell JD. Investigation for Genetic Determinants of Flexion Contractures and Contracted Foal Syndrome in Neonatal Thoroughbred Foals. [Doctoral Dissertation]. Texas A&M University; 2014. Available from: http://hdl.handle.net/1969.1/153856

Texas A&M University

11. Hulse-Kemp, Amanda M. Development of Genomic Markers and Mapping Tools for Assembling the Allotetraploid Gossypium hirsutum L. Draft Genome Sequence.

Degree: PhD, Genetics, 2015, Texas A&M University

URL: http://hdl.handle.net/1969.1/155055

► Cotton (Gossypium spp.) is the largest producer of natural textile fibers. Most worldwide and domestic cotton fiber production is based on cultivars of G. hirsutum… (more)

▼ Cotton (Gossypium spp.) is the largest producer of natural textile fibers. Most worldwide and domestic cotton fiber production is based on cultivars of G. hirsutum L., an allotetraploid. Genetic improvement of cotton remains constrained by alarmingly low levels of genetic diversity, inadequate genomic tools for genetic analysis and manipulation, and the difficulty of effectively harnessing the vastly greater genetic diversity harbored by other Gossypium species. Development of large numbers of single nucleotide polymorphisms (SNPs) for use in intraspecific and interspecific populations will allow for cotton germplasm diversity characterization, high-throughput genotyping, marker-assisted breeding, germplasm introgression of advantageous traits from wild species, and high-density genetic mapping. My research has been focused on utilizing next generation sequencing data for intraspecific and interspecific SNP marker development, validation, and creation of high-throughput genotyping methods to advance cotton research. I used transcriptome sequencing to develop and map the first gene-associated SNPs for five species, G. barbadense (Pima cotton), G. tomentosum, G. mustelinum, G. armourianum, and G. longicalyx. A total of 62,832 non-redundant SNPs were developed. These can be utilized for interspecific germplasm introgression into cultivated G. hirsutum, as well as for subsequent genetic analysis and manipulation. To create SNP-based resources for integrated physical mapping, I used BAC-end sequences (BESs) and resequecing data for 12 G. hirsutum lines, a Pima line and G. longicalyx to derive 132,262 intraspecific and 693,769 interspecific SNPs located in BESs. These SNP data sets were used to help build the first high-throughput genotyping array for cotton, the CottonSNP63K, which now provides a standardized platform for global cotton research. I applied the array to two F2 populations and produced the first two high-density SNP maps for cotton, one intraspecific and one interspecific. By resequencing two interspecific F1 hypo-aneuploids, I also demonstrated that the chromosome-wide changes in SNP genotypes enable highly effective mass-localization of BACs to individual cotton chromosomes. These efforts provide additional validation and placement methods that can be directly integrated with the physical map being constructed for G. hirsutum and enable the production of a high-quality draft genome sequence for cultivated cotton. I used transcriptome sequencing to develop and map the first gene-associated SNPs for five species, G. barbadense (Pima cotton), G. tomentosum, G. mustelinum, G. armourianum, and G. longicalyx. A total of 62,832 non-redundant SNPs were developed. These can be utilized for interspecific germplasm introgression into cultivated G. hirsutum, as well as for subsequent genetic analysis and manipulation. To create SNP-based resources for integrated physical mapping, I used BAC-end sequences (BESs) and resequecing data for 12 G. hirsutum lines, a Pima line and G. longicalyx to derive 132,262… Advisors/Committee Members: Stelly, David M (advisor), Pepper, Alan E (committee member), Gill, Clare A (committee member), Cai, James J (committee member).

Subjects/Keywords: Cotton; Genome Sequence; Single Nucleotide Polymorphism; Resequencing; Physical Mapping; Intraspecific; Interspecific

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hulse-Kemp, A. M. (2015). Development of Genomic Markers and Mapping Tools for Assembling the Allotetraploid Gossypium hirsutum L. Draft Genome Sequence. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/155055

Chicago Manual of Style (16^th Edition):

Hulse-Kemp, Amanda M. “Development of Genomic Markers and Mapping Tools for Assembling the Allotetraploid Gossypium hirsutum L. Draft Genome Sequence.” 2015. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/155055.

MLA Handbook (7^th Edition):

Hulse-Kemp, Amanda M. “Development of Genomic Markers and Mapping Tools for Assembling the Allotetraploid Gossypium hirsutum L. Draft Genome Sequence.” 2015. Web. 17 Jan 2021.

Vancouver:

Hulse-Kemp AM. Development of Genomic Markers and Mapping Tools for Assembling the Allotetraploid Gossypium hirsutum L. Draft Genome Sequence. [Internet] [Doctoral dissertation]. Texas A&M University; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/155055.

Council of Science Editors:

Hulse-Kemp AM. Development of Genomic Markers and Mapping Tools for Assembling the Allotetraploid Gossypium hirsutum L. Draft Genome Sequence. [Doctoral Dissertation]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/155055

Texas A&M University

12. Holland, Paul W. Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population.

Degree: MS, Animal Breeding, 2015, Texas A&M University

URL: http://hdl.handle.net/1969.1/155193

► The genetics of coat color for cattle are important to breeders and breed associations because phenotypes of these animals are used for breed recognition and… (more)

▼ The genetics of coat color for cattle are important to breeders and breed associations because phenotypes of these animals are used for breed recognition and premiums or discounts can be given due to the phenotypes. The gene for gray coat color has been determined in other species, but not in cattle. Gray in cattle is known to be recessive based upon observed inheritance. The objective of this study was to identify the regions of the bovine genome associated with gray coat color in a population of Nellore-Angus crossbred cattle. Additionally, proportions of each color and spotting were of interest. Animals (n = 1941) were classified into phenotypic color categories (i.e. red, black, gray, etc.). Proportions of each color group out of the population were determined, and the proportion of those phenotypes that have any form of spotting. Two genome-wide association analyses were conducted, one where phenotypically gray vs. not gray cattle were analyzed and another where cattle that were very light in color but had a reddish tinge were included as gray. Analyses used Bonferroni correction at α = 0.05 (α/ntests = 1.49 × 10^-6). Analysis of gray vs. not gray yielded one significant SNP marker on BTA6 at a location of 68,059,441 bp (Praw = 9.69 × 10^-7, Padjusted = 0.032) (UMD_3.1, NCBI project 32899, Gen Bank GCA_000003055.3). For the analysis of gray and reddish tinged vs. not gray, there were 5 significant markers all on BTA6 forming a region from 62.93 Mb to 83.92 Mb (UMD_3.1, NCBI project 32899, Gen Bank GCA_000003055.3).The same SNP marker from the first analysis was present in the second, but had an increased significance (Praw = 1.50 × 10^-10, Padjusted = 5.02 × 10^-6). The region on BTA6 ruled out syntaxin-17 (STX17) on BTA8 and premelanosome protein (PMEL) on BTA5, previous gray candidate genes from other species, but includes genes such as v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), which is known to cause white coloration (spotting), and platelet-derived growth factor receptor alpha polypeptide (PDGFRA), the strongest candidate gene for the reddening in Nellore-Angus cattle, and corin serin pepsidase (CORIN), known for lighter coloration. Advisors/Committee Members: Riley, David G (advisor), Sanders, James O (committee member), Gill, Clare A (committee member), Herring, Andy D (committee member).

Subjects/Keywords: Gray; coat color; cattle; Nellore; Angus; genome-wide association; CORIN; PDGFRA

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Holland, P. W. (2015). Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/155193

Chicago Manual of Style (16^th Edition):

Holland, Paul W. “Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population.” 2015. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/155193.

MLA Handbook (7^th Edition):

Holland, Paul W. “Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population.” 2015. Web. 17 Jan 2021.

Vancouver:

Holland PW. Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population. [Internet] [Masters thesis]. Texas A&M University; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/155193.

Council of Science Editors:

Holland PW. Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population. [Masters Thesis]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/155193

Texas A&M University

13. Chhatre, Vikram E. Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.).

Degree: PhD, Genetics, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/149610

► Loblolly pine (Pinus taeda L.) is an ecologically and economically important southern pine, distributed across the southeastern United States. Its genetic improvement for breeding and… (more)

▼ Loblolly pine (Pinus taeda L.) is an ecologically and economically important southern pine, distributed across the southeastern United States. Its genetic improvement for breeding and deployment is a major goal of the Western Gulf Forest Tree Improvement Program (WGFTIP) hosted by the Texas A&M Forest Service. Rapid advances in genomics and molecular marker technology have created potential for application of Marker Assisted Selection (MAS) and Genomic Selection (GS) for accelerated breeding in forest trees. First-generation selection (FGS) and second- generation selection (SGS) breeding populations of loblolly pine from east Texas were studied to estimate the genetic diversity, population structure, linkage disequilibrium (LD), signatures of selection and association of breeding traits with genetic markers using a genome-wide panel of 4264 single nucleotide polymorphisms (SNPs). Under- standing the genetic basis of local adaptation is crucial to disentangle the dynamics of gene flow, drift and selection and to address climate change. Bayesian mixed linear models and logistic regression were used to associate SNP variation with geography, climate, aridity and growth season length and markers with strong correlations were investigated for biological functions. Relatively high levels of observed (Ho = 0.178–0.198) and expected (He = 0.180-0.198) heterozygosities were found in all populations. The amount of inbreeding was very low, and many populations exhibited a slight excess of heterozygotes. The population substructure was weak, but FST indicated more pronounced differentiation in the SGS populations. As expected for outcrossing natural populations, the genome-wide LD was low, but marker density was insufficient to deduce the decay rate. Numerous associations were found between various phenotypes and SNPs, but few remained significant after false positive correction. Signatures of diversifying and balancing selection were found in markers representing important biological functions. Strong correlations supported by Bayes factors were found between various environmental variables and several SNPs. Logistic regression found hundreds of significant marker-environment associations, but none remained significant after false-positive correction, which was likely too stringent and will require further investigation. Annotations of significant markers implicated them in crucial biological functions. These results present the first step in the application of MAS to the WGFTIP for loblolly pine genetic improvement and will contribute to the knowledgebase necessary for genomic selection technology. Results from environmental association study provide important information for designing breeding strategies to address climate change and for genetic conservation purposes. Advisors/Committee Members: Krutovsky, Konstantin V (advisor), Byram, Thomas D (advisor), Gill, Clare A (committee member), Pepper, Alan E (committee member).

Subjects/Keywords: loblolly pine; Pinus taeda; association mapping; population structure; landscape genomics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chhatre, V. E. (2013). Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.). (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/149610

Chicago Manual of Style (16^th Edition):

Chhatre, Vikram E. “Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.).” 2013. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/149610.

MLA Handbook (7^th Edition):

Chhatre, Vikram E. “Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.).” 2013. Web. 17 Jan 2021.

Vancouver:

Chhatre VE. Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.). [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/149610.

Council of Science Editors:

Chhatre VE. Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.). [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/149610

Texas A&M University

14. Hulsman, Lauren Lorene. Investigation of Genomic Estimated Breeding Values and Association Methodologies using Bayesian Inference in a Nellore-Angus Crossbred Population for Two Traits.

Degree: PhD, Animal Breeding, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/150978

► The objectives of this study were to 1) evaluate marker associations for genomic regions of interest and significant ontology terms, 2) evaluate and compare 4… (more)

▼ The objectives of this study were to 1) evaluate marker associations for genomic regions of interest and significant ontology terms, 2) evaluate and compare 4 models for their efficacy in predicting genetic merit, 3) evaluate and compare the impact of using breed-of-origin genotypes in a Bayesian prediction model, and 4) evaluate the effects of data partitioning using family structure on predictions. Nellore-Angus F2, F3 and half-sibling calves were used with records for overall temperament at weaning (OTW; a subjective scoring system; n = 769) and Warner-Bratzler shear force (WBSF; a measure of tenderness; n = 389). After filtering, 34,913 markers were available for use. Bayesian methods employed were BayesB (using ̂) and BayesC (using π = 0 and ̂) in GenSel software, where, after estimation, π ̂ = 0.995 or 0.997 for WBSF or OTW, respectively. No regions associated with either trait were found using π ̂, but when π = 0 associated regions were identified (37 and 147 regions for OTW and WBSF, respectively). Comparison of genomic estimated breeding values from these 3 Bayesian models to an animal model showed that BayesC procedures (using ̂) had the highest accuracy for both traits, but that BayesB had the lowest indication of bias in either case. Using a subset of the population (n = 440), genotypes based on the breed in which the alleles originated from (i.e., breed-of-origin genotypes) were assigned to markers mapped to autosomes (n = 34,449), and incorporated into prediction analyses using BayesB (π ̂ = 0.997) with or without nucleotide-based genotypes. In either case, there was an increase in accuracy when breed-of-origin genotypes were incorporated into prediction analyses. Data partitions based on family structure resulted in 13 distinct training and validations groups. Relationship of individuals in the training with validation individuals did have an impact in some cases, but not all. There was poor prediction of genomic estimated breeding values for individuals in the validation population using BayesB methods, but performed better in all cases than breeding values generated using an animal model. Future studies incorporating breed-of-origin genotypes are of interest to determine if accuracy is improved in these groups. Advisors/Committee Members: Riley, David G (advisor), Garrick, Dorian J (committee member), Gill, Clare A (committee member), Sanders, James O (committee member).

Subjects/Keywords: genomic estimated breeding values; crossbred cattle; Bayesian Inference; overall temperament at weaning; Warner-Bratzler shear force

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hulsman, L. L. (2013). Investigation of Genomic Estimated Breeding Values and Association Methodologies using Bayesian Inference in a Nellore-Angus Crossbred Population for Two Traits. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/150978

Chicago Manual of Style (16^th Edition):

Hulsman, Lauren Lorene. “Investigation of Genomic Estimated Breeding Values and Association Methodologies using Bayesian Inference in a Nellore-Angus Crossbred Population for Two Traits.” 2013. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/150978.

MLA Handbook (7^th Edition):

Hulsman, Lauren Lorene. “Investigation of Genomic Estimated Breeding Values and Association Methodologies using Bayesian Inference in a Nellore-Angus Crossbred Population for Two Traits.” 2013. Web. 17 Jan 2021.

Vancouver:

Hulsman LL. Investigation of Genomic Estimated Breeding Values and Association Methodologies using Bayesian Inference in a Nellore-Angus Crossbred Population for Two Traits. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/150978.

Council of Science Editors:

Hulsman LL. Investigation of Genomic Estimated Breeding Values and Association Methodologies using Bayesian Inference in a Nellore-Angus Crossbred Population for Two Traits. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/150978

Texas A&M University

15. Grützner, Niels. Cobalamin (Vitamin B_(12)) Deficiency in the Chinese Shar Pei – Evaluation of a Potential Hereditary Etiology.

Degree: PhD, Biomedical Sciences, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151939

► In recent history, no other dog breed has grown in popularity and/or population size in such a short period of time as is the case… (more)

Subjects/Keywords: Cobalamin (vitamin B12) deficiency; Shar Peis; GWAS; homocysteine; methylmalonic acid

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APA (6^th Edition):

Grützner, N. (2013). Cobalamin (Vitamin B_(12)) Deficiency in the Chinese Shar Pei – Evaluation of a Potential Hereditary Etiology. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151939

Chicago Manual of Style (16^th Edition):

Grützner, Niels. “Cobalamin (Vitamin B_(12)) Deficiency in the Chinese Shar Pei – Evaluation of a Potential Hereditary Etiology.” 2013. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/151939.

MLA Handbook (7^th Edition):

Grützner, Niels. “Cobalamin (Vitamin B_(12)) Deficiency in the Chinese Shar Pei – Evaluation of a Potential Hereditary Etiology.” 2013. Web. 17 Jan 2021.

Vancouver:

Grützner N. Cobalamin (Vitamin B_(12)) Deficiency in the Chinese Shar Pei – Evaluation of a Potential Hereditary Etiology. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/151939.

Council of Science Editors:

Grützner N. Cobalamin (Vitamin B_(12)) Deficiency in the Chinese Shar Pei – Evaluation of a Potential Hereditary Etiology. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151939

16. Hulsman, Lauren L. Identification of Loci Interacting with Melanocortin-1 Receptor to Modify Black Coat Color in an F2 Nellore-Angus Population.

Degree: MS, Animal Breeding, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7830

► In cattle, base color is attributed to activity at the melanocortin-1 receptor (MC1R), historically termed the extension locus, with alleles coding for black (ED), red… (more)

▼ In cattle, base color is attributed to activity at the melanocortin-1 receptor (MC1R), historically termed the extension locus, with alleles coding for black (ED), red (e), and wild-type (E+). These alleles, in most mammals, are presumed to follow the dominance model ED > E+ > e, although exceptions are often seen. In Bos indicus x Bos taurus F2 cattle, EDE+ heterozygotes observed were discordant with the dominance series for the MC1R alleles and displayed various degrees of reddening on an otherwise predicted black background. The objective of this study was to identify loci modifying black coat color in these individuals. The hypothesis was that degree of reddening was a quantitative trait controlled by multiple genes of small effect. Reddening was classified utilizing photographs for 5 subjective scoring systems and analyzed by general linear model procedures of SAS with fixed effects of sex, sire, family nested within sire, season of photo, and spotted status. Residuals from these models were utilized for interval analyses to identify quantitative trait loci (QTL). Analyses of 19 bovine autosomal chromosomes, identified chromosome-wise suggestive (P < 0.05) and significant (P < 0.01) QTL on bovine chromosomes (BTA) 4, 5, 15, 18, 21, 27, and 29. Unexpectedly, there was evidence of a major gene (F = 67.88) affecting reddening at 71 Mb of BTA 6 (based on build Btau4.0 of the bovine genome sequence) that accounted for 61.1% of the variation in reddening. This QTL coincided closely with a cluster of tyrosine kinase receptor genes (PDGFRA, KIT and KDR). Fitting SNP haplotypes for a 1 Mb region containing all 3 genes and centered on KIT accounted for all the variation attributed to this QTL. These data suggested that one of these 3 genes, or a gene in high linkage disequilibrium with them, was responsible for the majority of variation in degree of reddening. Two recombinants within this region identified PDGFRA as the strongest candidate gene. Functional analyses will be required to verify the role of PDGFRA and its interaction with MC1R to modify black coat color of Bos indicus influenced cattle. Advisors/Committee Members: Gill, Clare A. (advisor), Herring, Andy (committee member), Sanders, James O. (committee member).

Subjects/Keywords: MC1R; Reddening; Cattle; QTL; PDGFRA

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APA (6^th Edition):

Hulsman, L. L. (2011). Identification of Loci Interacting with Melanocortin-1 Receptor to Modify Black Coat Color in an F2 Nellore-Angus Population. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7830

Chicago Manual of Style (16^th Edition):

Hulsman, Lauren L. “Identification of Loci Interacting with Melanocortin-1 Receptor to Modify Black Coat Color in an F2 Nellore-Angus Population.” 2011. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7830.

MLA Handbook (7^th Edition):

Hulsman, Lauren L. “Identification of Loci Interacting with Melanocortin-1 Receptor to Modify Black Coat Color in an F2 Nellore-Angus Population.” 2011. Web. 17 Jan 2021.

Vancouver:

Hulsman LL. Identification of Loci Interacting with Melanocortin-1 Receptor to Modify Black Coat Color in an F2 Nellore-Angus Population. [Internet] [Masters thesis]. Texas A&M University; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7830.

Council of Science Editors:

Hulsman LL. Identification of Loci Interacting with Melanocortin-1 Receptor to Modify Black Coat Color in an F2 Nellore-Angus Population. [Masters Thesis]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7830

17. Zhong, Ming. Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans.

Degree: PhD, Statistics, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687

► Positive natural selection is recognized as the driving force underneath evolution. One of the surest signatures of recent positive selection is a local elevation of… (more)

▼ Positive natural selection is recognized as the driving force underneath evolution. One of the surest signatures of recent positive selection is a local elevation of advantageous allele frequency and linkage disequilibrium (LD). This dissertation proposes a new test statistic to detect excess homozygosity based on a simple counting measure, which serves as a surrogate indicator of recent positive selection. Three tests are developed upon the new measure: (a) an extended genotype-based homozy- gosity test (EGHT), (b) a hidden Markov model test (HMMT), and (c) an extended haplotype-based homozygosity test (EHHT). The null hypotheses of all three tests assume random mating and Hardy-Weinberg equilibrium (HWE). They differ in how to treat LD under H0 . The EGHT assumes linkage equilibrium (LE) besides HWE while the EHHT allows arbitrary multi-locus LD. The HMMT stands between these two extremes and assumes pairwise but no higher-order disequilibrium interactions. We first conduct simulation study to compare the three score tests and verify that the EHHT is the most conservative one. We compare the performance of the EHHT with the prevailing detection methods and the EHHT has higher or similar power. We also evaluate the impact of simple demographic history on the EHHT and the simulation study suggests that the EHHT is resistant to the false-positive confounders resulting from simple demographic models. After extensive simulation studies, all three tests are then applied on HapMap Phase II data and we are able to replicate findings reported in the literature. We can also identify new candidate regions that may undergo recent selection through a set of filtering criteria including highest EHHT scores, high derived allele frequency and large population differentiation. Finally, we propose a cross-population comparison test statistic to detect chromosome regions in which there is no significant excess homozygosity in one population but homozygosity remains high in another population. Advisors/Committee Members: Fan, Ruzong (advisor), Carroll, Raymond J. (committee member), Gill, Clare (committee member), Longnecker, Michael (committee member).

Subjects/Keywords: Extended homozygosity; linkage disequilibrium; positive selection.

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APA (6^th Edition):

Zhong, M. (2011). Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687

Chicago Manual of Style (16^th Edition):

Zhong, Ming. “Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans.” 2011. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687.

MLA Handbook (7^th Edition):

Zhong, Ming. “Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans.” 2011. Web. 17 Jan 2021.

Vancouver:

Zhong M. Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans. [Internet] [Doctoral dissertation]. Texas A&M University; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687.

Council of Science Editors:

Zhong M. Extended Homozygosity Score Tests to Detect Positive Selection in Genome-wide Scans. [Doctoral Dissertation]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7687

18. Peer, Shawna Marie. Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species.

Degree: MS, Animal Science, 2015, Texas A&M University

URL: http://hdl.handle.net/1969.1/155275

► The presence and activity of glutathione S-transferase alpha 3 (GSTA3) in the testosterone biosynthesis pathway of humans and multiple mammalian species is a new concept.… (more)

▼ The presence and activity of glutathione S-transferase alpha 3 (GSTA3) in the testosterone biosynthesis pathway of humans and multiple mammalian species is a new concept. Some researchers have hypothesized that the gene encoding GSTA3 is conserved across many other species. This study undertakes characterization of the GSTA3 gene products in multiple diverse species in order to demonstrate its conservation. The species analyzed here include Canis lupus familiaris, Capra hircus, Monodelphis domestica, and Gallus gallus. Testis samples from each of these species were taken, RNA was isolated, reverse transcribed, and the GSTA3 cDNA was cloned and sequenced with polymerase chain reaction (PCR) technologies. cDNA sequences were then analyzed with the NCBI BLAST algorithm, ExPASy Translate tool, and Clustal Omega Multiple Sequence Alignment tool. These tools were also used to compare the cloned cDNAs to a reference sequence from Homo sapiens (GenBank accession number XM_000847.4) and an Equus caballus sequence published in the NCBI database (KC512384). GSTA3 cDNA sequences obtained for each species were submitted to NCBI GenBank. A set of multiple tissue samples was taken from both Equus caballus and Canis lupus familiaris. These tissue samples were analyzed for the expression of GSTA3 mRNA in each tissue after RNA isolation, reverse transcription and quantitative polymerase chain reaction (qRT-PCR). cDNA data analysis demonstrated GSTA3 gene conservation at the DNA level in all the species studied. Real time quantitative PCR data demonstrated significantly high concentrations of the GSTA3 mRNA in the testes and adrenal glands as compared to all other tissues for the equine multi-tissue analysis as expected. Dissimilarly, the canine multiple tissue analysis indicated that the concentration of GSTA3 mRNA was high in the liver and small intestine as well as the testes and adrenal glands. Other researchers have reported high concentrations of GSTA3 mRNA in the liver and small intestine previously. Advisors/Committee Members: Ing, Nancy H (advisor), Vogelsang, Martha M (committee member), Gill, Clare A (committee member).

Subjects/Keywords: Glutathione S-transferase Alpha 3; Testosterone; Steroidogenesis; Glucocorticoids

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APA (6^th Edition):

Peer, S. M. (2015). Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/155275

Chicago Manual of Style (16^th Edition):

Peer, Shawna Marie. “Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species.” 2015. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/155275.

MLA Handbook (7^th Edition):

Peer, Shawna Marie. “Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species.” 2015. Web. 17 Jan 2021.

Vancouver:

Peer SM. Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species. [Internet] [Masters thesis]. Texas A&M University; 2015. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/155275.

Council of Science Editors:

Peer SM. Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species. [Masters Thesis]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/155275

19. Yi, Gang Man. Algorithms for Gene Clustering Analysis on Genomes.

Degree: PhD, Computer Science, 2012, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9384

► The increased availability of data in biological databases provides many opportunities for understanding biological processes through these data. As recent attention has shifted from sequence… (more)

▼ The increased availability of data in biological databases provides many opportunities for understanding biological processes through these data. As recent attention has shifted from sequence analysis to higher-level analysis of genes across multiple genomes, there is a need to develop efficient algorithms for these large-scale applications that can help us understand the functions of genes. The overall objective of my research was to develop improved methods which can automatically assign groups of functionally related genes in large-scale data sets by applying new gene clustering algorithms. Proposed gene clustering algorithms that can help us understand gene function and genome evolution include new algorithms for protein family classification, a window-based strategy for gene clustering on chromosomes, and an exhaustive strategy that allows all clusters of small size to be enumerated. I investigate the problems of gene clustering in multiple genomes, and define gene clustering problems using mathematical methodology and solve the problems by developing efficient and effective algorithms. For protein family classification, I developed two supervised classification algorithms that can assign proteins to existing protein families in public databases and, by taking into account similarities between the unclassified proteins, allows for progressive construction of new families from proteins that cannot be assigned. This approach is useful for rapid assignment of protein sequences from genome sequencing projects to protein families. A comparative analysis of the method to other previously developed methods shows that the algorithm has a higher accuracy rate and lower mis-classification rate when compared to algorithms that are based on the use of multiple sequence alignments and hidden Markov models. The proposed algorithm performs well even on families with very few proteins and on families with low sequence similarity. Apart from the analysis of individual sequences, identifying genomic regions that descended from a common ancestor helps us study gene function and genome evolution. In distantly related genomes, clusters of homologous gene pairs serve as evidence used in function prediction, operon detection, etc. Thus, reliable identification of gene clusters is critical to functional annotation and analysis of genes. I developed an efficient gene clustering algorithm that can be applied on hundreds of genomes at the same time. This approach allows for large-scale study of evolutionary relationships of gene clusters and study of operon formation and destruction. By placing a stricter limit on the maximum cluster size, I developed another algorithm that uses a different formulation based on constraining the overall size of a cluster and statistical estimates that allow direct comparisons of clusters of different size. A comparative analysis of proposed algorithms shows that more biological insight can be obtained by analyzing gene clusters across hundreds of genomes, which can help us understand operon occurrences,… Advisors/Committee Members: Sze, Sing-Hoi (advisor), Choe, Yoonsuck (committee member), Williams, Tiffani L. (committee member), Gill, Clare (committee member).

Subjects/Keywords: gene clustering; protein family; bioinformatics

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APA (6^th Edition):

Yi, G. M. (2012). Algorithms for Gene Clustering Analysis on Genomes. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9384

Chicago Manual of Style (16^th Edition):

Yi, Gang Man. “Algorithms for Gene Clustering Analysis on Genomes.” 2012. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9384.

MLA Handbook (7^th Edition):

Yi, Gang Man. “Algorithms for Gene Clustering Analysis on Genomes.” 2012. Web. 17 Jan 2021.

Vancouver:

Yi GM. Algorithms for Gene Clustering Analysis on Genomes. [Internet] [Doctoral dissertation]. Texas A&M University; 2012. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9384.

Council of Science Editors:

Yi GM. Algorithms for Gene Clustering Analysis on Genomes. [Doctoral Dissertation]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9384

20. Navarrette, Ashley Elizabeth. Genomic Differences Between Highly Fertile and Sub-Fertile Holstein Dairy Heifers.

Degree: MS, Physiology of Reproduction, 2012, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-10999

► Infertility in dairy cattle remains a major economic loss to dairy producers. Identifying dairy cattle with superior genetic potential for improved fertility would increase dairy… (more)

▼ Infertility in dairy cattle remains a major economic loss to dairy producers. Identifying dairy cattle with superior genetic potential for improved fertility would increase dairy farm profitability. Dairy heifers were classified into two groups based upon services per conception (SPC); those animals with a single SPC were determined to be highly fertile and animals with greater than or equal to 4 SPC were classified as sub-fertile. Whole genome association analysis was performed on 20 individual heifers from each group utilizing a 777K highly density (HD) single nucleotide polymorphism (SNP) chip. Genomic data were evaluated utilizing PLINK, a whole genome association analysis toolset, and 570,620 SNP were available for analysis with a total of 39 samples being analyzed. Forty-four SNP were determined to be associated with fertility classification (P <= 0.00001) and were located on Bos taurus chromosome (BTA) 2, 4, 9, 19, and 26. The SNP and ranges between SNP were analyzed using BLAST-Like Alignment Tool (BLAT); SNP were associated with 5 candidate genes for reproduction. The SNP on BTA 2 were located within the region coding for the non-imprinted Prader-Willi/Angelman syndrome 2 (NIPA2) gene, which is involved in gestational magnesium transport. Also on BTA 2, SNP were identified within the region encoding for cytoplasmic fragile X mental retardation 1 (FMR1) interaction protein 1 (CYFIP1). The CYFIP1 gene is involved with the functionality of FMR1 and has been linked to premature ovarian failure in humans. Additionally, 3 SNP on BTA 9 were located near monofunctional C1-tetrahydrofolate synthase (MTHFD1L), which has been linked to neural tube defects during gestation in humans A difference in allele frequency was observed between the two groups for SNP located on BTA19 in proximity to two genes, zinc finger 18 (ZNF18) and mitogen activated protein kinase 4 (MAP2K4). The ZNF18 motif and MAP2K4 were found to be involved in heart development of the early embryo and associated with toll-like receptors (TLR) involved in gonadotropin releasing hormone (GnRH) signaling, respectively. The involvement of one or all of these genes may further explain reduced fertility in dairy cattle. Advisors/Committee Members: Bilby, Todd R. (advisor), Spencer, Thomas E. (committee member), Long, Charles R. (committee member), Gill, Clare A. (committee member).

Subjects/Keywords: dairy; SNP; genomics; fertility

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APA (6^th Edition):

Navarrette, A. E. (2012). Genomic Differences Between Highly Fertile and Sub-Fertile Holstein Dairy Heifers. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-10999

Chicago Manual of Style (16^th Edition):

Navarrette, Ashley Elizabeth. “Genomic Differences Between Highly Fertile and Sub-Fertile Holstein Dairy Heifers.” 2012. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-10999.

MLA Handbook (7^th Edition):

Navarrette, Ashley Elizabeth. “Genomic Differences Between Highly Fertile and Sub-Fertile Holstein Dairy Heifers.” 2012. Web. 17 Jan 2021.

Vancouver:

Navarrette AE. Genomic Differences Between Highly Fertile and Sub-Fertile Holstein Dairy Heifers. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-10999.

Council of Science Editors:

Navarrette AE. Genomic Differences Between Highly Fertile and Sub-Fertile Holstein Dairy Heifers. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-10999

21. Hilley, Josie Lynn. Taking Sorghum to New Heights: Identification of Genes Controlling Height Variation in Sorghum.

Degree: PhD, Genetics, 2017, Texas A&M University

URL: http://hdl.handle.net/1969.1/161445

► Sorghum is an important cereal crop worldwide though it is particularly important in semi-arid regions. It is grown for many uses including food, feed, forage,… (more)

Subjects/Keywords: sorghum; height; dwarfing genes

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APA (6^th Edition):

Hilley, J. L. (2017). Taking Sorghum to New Heights: Identification of Genes Controlling Height Variation in Sorghum. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/161445

Chicago Manual of Style (16^th Edition):

Hilley, Josie Lynn. “Taking Sorghum to New Heights: Identification of Genes Controlling Height Variation in Sorghum.” 2017. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/161445.

MLA Handbook (7^th Edition):

Hilley, Josie Lynn. “Taking Sorghum to New Heights: Identification of Genes Controlling Height Variation in Sorghum.” 2017. Web. 17 Jan 2021.

Vancouver:

Hilley JL. Taking Sorghum to New Heights: Identification of Genes Controlling Height Variation in Sorghum. [Internet] [Doctoral dissertation]. Texas A&M University; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/161445.

Council of Science Editors:

Hilley JL. Taking Sorghum to New Heights: Identification of Genes Controlling Height Variation in Sorghum. [Doctoral Dissertation]. Texas A&M University; 2017. Available from: http://hdl.handle.net/1969.1/161445

22. Wunderlich, Kris Rakowitz. Structural and functional characterization of the polled interval on bovine chromosome 1.

Degree: PhD, Genetics, 2008, Texas A&M University

URL: http://hdl.handle.net/1969.1/85933

► The horned condition in cattle is believed to be the wild type with morphogenesis primarily occurring after birth. The polled condition has existed since domestication… (more)

▼ The horned condition in cattle is believed to be the wild type with morphogenesis primarily occurring after birth. The polled condition has existed since domestication and has been selected for its economic importance. The polled locus has previously been mapped by genetic linkage analysis to the proximal region of bovine chromosome 1. In order to help us eventually identify the causative mutation, the objective of the study was to structurally and functionally characterize the polled interval from IFNAR1 to SOD1 on BTA1. Our hypothesis was that the polled locus is a tissue specific transcription factor that is expressed in the developing horn buds and acts directly or indirectly upon SOX9. A 2.5 Mb BAC contig and STS content map of the polled interval was constructed. Three candidate genes encoding transcription factors were identified within this region but only C21orf66 was expressed in the horn buds from 1 d old Bos indicus influenced calves. The C21orf66 gene has 18 exons, spans 30,976 bp of genomic DNA, and 144 SNP were identified. No single SNP discovered in C21orf66 can be attributed as the causative mutation. None of the genes from the polled interval were differentially expressed in skin and horn from 1 d old Bos indicus influenced calves. However, there were significant differences in the levels of expression of RUNX2, SOX9, BMP4, PRKCA, and FOXL2 in these samples. Expression of RUNX2 was localized to the osteoblasts, and both RUNX2 and SOX9 were expressed in sebaceous glands of the horn at 1 d of age. Histological examination of horns and scurs from newborn, 5 to 6 mo, and ~1.5 yr old Bos indicus influenced cattle suggest that horns form through intramembranous ossification. Based on the data presented herein, we propose that the polled locus is upstream of RUNX2 and SOX9 in the osteogenic pathway, and could have its primary effect on the differentiation of mesenchymal condensations. The genes IL10RB, SFRS15, C21orf66, OLIG1, OLIG2 and HUNK remain candidates for the polled locus and warrant further investigation. Advisors/Committee Members: Gill, Clare A. (advisor), Herring, Andy D. (committee member), Sanders, James O. (committee member), Spencer, Thomas E. (committee member).

Subjects/Keywords: Horn; Polled; Bovine; Chromosome 1; Gene Expression

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APA (6^th Edition):

Wunderlich, K. R. (2008). Structural and functional characterization of the polled interval on bovine chromosome 1. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/85933

Chicago Manual of Style (16^th Edition):

Wunderlich, Kris Rakowitz. “Structural and functional characterization of the polled interval on bovine chromosome 1.” 2008. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/85933.

MLA Handbook (7^th Edition):

Wunderlich, Kris Rakowitz. “Structural and functional characterization of the polled interval on bovine chromosome 1.” 2008. Web. 17 Jan 2021.

Vancouver:

Wunderlich KR. Structural and functional characterization of the polled interval on bovine chromosome 1. [Internet] [Doctoral dissertation]. Texas A&M University; 2008. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/85933.

Council of Science Editors:

Wunderlich KR. Structural and functional characterization of the polled interval on bovine chromosome 1. [Doctoral Dissertation]. Texas A&M University; 2008. Available from: http://hdl.handle.net/1969.1/85933

23. Cooper, Aaron Jay. Evaluation of Udder Conformation, Weight, Body Condition, Reproduction, Disposition, and Calf Growth in Bos indicus – Bos taurus Cows.

Degree: PhD, Animal Breeding, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10203

► Data were analyzed on 2 to 6 yr old cows to evaluate sire and family effects. Cows were produced in the McGregor Genomics Project from… (more)

▼ Data were analyzed on 2 to 6 yr old cows to evaluate sire and family effects. Cows were produced in the McGregor Genomics Project from 13 embryo transfer (ET) full sib families (n = 188, F2 Nellore-Angus (NA)) and 4 half sib natural service (NS) families (n = 114, out of 1/2 Brahman 1/2 British dams) from the same 4 F1 NA sires. The ET and NS cows were analyzed separately and together as paternal half sibs (PHS). Daughters of bull 437J had the highest calving rate and weaning rate; daughters of 551G were the lowest in ET, and daughters of 297J were the lowest in NS. Calves out of daughters of 551G were the heaviest at birth; those from of daughters of 437J were the lightest in NS and PHS. Calves out of daughters of 297J were the heaviest at weaning in ET and PHS, and those from daughters of 432H were the lightest. Calves from daughters of 297J and 437J gained the most weight and those from daughters of 432H gained the least. Daughters of 297J and 551G had longer and larger diameter teats and lower udder support scores (more pendulous) than daughters of 432H and 437J. Daughters of 437J had the highest body condition score (BCS); daughters of 551G were the lowest in ET and NS. Calves from daughters of 297J had the highest BCS at weaning. Those out of daughters of 551G had the lightest WWT, those out of daughters of 437J were the heaviest in NS and PHS, and those out of daughters of 432H were the heaviest in ET. Daughters of 437J and 551G scored the highest for disposition (least docile) in ET and PHS, and daughters of 432H were lowest. The regression of WWT on weaning age was 0.82 plus/minus 0.07 in ET, 0.71 plus/minus 0.08 in NS, and 0.78 plus/minus 0.05 kg/d in PHS. There appears to be sufficient variation within and between these full sib and half sib families for use in QTL analysis for major genes affecting cow productivity in NA crosses. Advisors/Committee Members: Sanders, Jim O. (advisor), Herring, Andy D. (committee member), Riley, David G. (committee member), Gill, Clare A. (committee member), Sawyer, Jason E. (committee member).

Subjects/Keywords: Bos indicus-Bos taurus cow; productivity udder conformation reproduction disposition

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APA (6^th Edition):

Cooper, A. J. (2011). Evaluation of Udder Conformation, Weight, Body Condition, Reproduction, Disposition, and Calf Growth in Bos indicus – Bos taurus Cows. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10203

Chicago Manual of Style (16^th Edition):

Cooper, Aaron Jay. “Evaluation of Udder Conformation, Weight, Body Condition, Reproduction, Disposition, and Calf Growth in Bos indicus – Bos taurus Cows.” 2011. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10203.

MLA Handbook (7^th Edition):

Cooper, Aaron Jay. “Evaluation of Udder Conformation, Weight, Body Condition, Reproduction, Disposition, and Calf Growth in Bos indicus – Bos taurus Cows.” 2011. Web. 17 Jan 2021.

Vancouver:

Cooper AJ. Evaluation of Udder Conformation, Weight, Body Condition, Reproduction, Disposition, and Calf Growth in Bos indicus – Bos taurus Cows. [Internet] [Doctoral dissertation]. Texas A&M University; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10203.

Council of Science Editors:

Cooper AJ. Evaluation of Udder Conformation, Weight, Body Condition, Reproduction, Disposition, and Calf Growth in Bos indicus – Bos taurus Cows. [Doctoral Dissertation]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-10203

Texas A&M University

24. Butler, Lara Elizabeth. Honey bee gene regulation and transcriptional effects of a pheromone and a parasite.

Degree: MS, Genetics, 2009, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2748

► The European honey bee, Apis mellifera, is a primarily beneficial insect for mankind. It has been utilized by humans for thousands of years for the… (more)

Subjects/Keywords: Apis mellifera; Varroa; QMP; honey bee; pheromone

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APA (6^th Edition):

Butler, L. E. (2009). Honey bee gene regulation and transcriptional effects of a pheromone and a parasite. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2748

Chicago Manual of Style (16^th Edition):

Butler, Lara Elizabeth. “Honey bee gene regulation and transcriptional effects of a pheromone and a parasite.” 2009. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2748.

MLA Handbook (7^th Edition):

Butler, Lara Elizabeth. “Honey bee gene regulation and transcriptional effects of a pheromone and a parasite.” 2009. Web. 17 Jan 2021.

Vancouver:

Butler LE. Honey bee gene regulation and transcriptional effects of a pheromone and a parasite. [Internet] [Masters thesis]. Texas A&M University; 2009. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2748.

Council of Science Editors:

Butler LE. Honey bee gene regulation and transcriptional effects of a pheromone and a parasite. [Masters Thesis]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2748

Texas A&M University

25. Funkhouser, Rena Rebecca. Evaluation of disposition scores in Bos indicus/Bos taurus cross calves at different stages of production.

Degree: MS, Animal Breeding, 2008, Texas A&M University

URL: http://hdl.handle.net/1969.1/85987

► Aggressiveness, nervousness, flightiness, gregariousness and overall disposition were evaluated in F2 Nellore-Angus embryo transfer calves (n = 443) from 13 full sib families and in… (more)

▼ Aggressiveness, nervousness, flightiness, gregariousness and overall disposition were evaluated in F2 Nellore-Angus embryo transfer calves (n = 443) from 13 full sib families and in half Bos indicus, half Bos taurus natural service calves (n = 259) from 4 paternal half sib families. Calves were born from 2003 to 2007, and evaluated shortly after weaning. Steers were evaluated shortly before slaughter for all 5 disposition traits and at slaughter for overall disposition. Heifers were evaluated for overall disposition at calving every year. Scores ranged from 1 to 9, with 1 being docile and 9 being unruly, except at calving where scores ranged from 1 to 5. Between sires for overall disposition, calves by 297J were lowest at weaning (2.83), before slaughter (2.84), and at slaughter (2.45) and second lowest in first calf heifers (2.27). Calves by 437J were highest at weaning (4.10), before slaughter (3.54), at slaughter (2.89) and in first calf heifers (3.10). Bulls had the lowest scores at weaning (2.54), although the number was small (n=10); females were the highest (4.01), and steers were intermediate (3.70). All 5 weaning traits were correlated (P < 0.05) with each other (0.73 to 0.96). The correlation of recipient disposition and weaning disposition of the calves was 0.12 (P < 0.05). Aggressiveness was not significantly correlated with other component traits before slaughter but was with overall disposition (0.19, P < 0.05). All other traits were significantly inter-correlated (0.60 to 0.97). Disposition at weaning was correlated with disposition before slaughter (0.43, P < 0.05). Slaughter disposition was correlated with weaning disposition (0.30, P < 0.001) and disposition before slaughter (0.27, P < 0.001). Disposition in first calf heifers was correlated with weaning disposition (0.34, P < 0.001) and disposition in second calf females (0.53, P < 0.0001). The results indicate that both genetics and recipient disposition affect calf disposition at weaning, calves with better dispositions at weaning have better dispositions later in life, and there is sufficient variability within and between these full sib and half sib families for use in QTL analysis for major genes for disposition in Nellore-Angus cross cattle. Advisors/Committee Members: Sanders, James O. (advisor), Herring, Andy D. (committee member), Gill, Clare (committee member).

Subjects/Keywords: disposition; cattle

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APA (6^th Edition):

Funkhouser, R. R. (2008). Evaluation of disposition scores in Bos indicus/Bos taurus cross calves at different stages of production. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/85987

Chicago Manual of Style (16^th Edition):

Funkhouser, Rena Rebecca. “Evaluation of disposition scores in Bos indicus/Bos taurus cross calves at different stages of production.” 2008. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/85987.

MLA Handbook (7^th Edition):

Funkhouser, Rena Rebecca. “Evaluation of disposition scores in Bos indicus/Bos taurus cross calves at different stages of production.” 2008. Web. 17 Jan 2021.

Vancouver:

Funkhouser RR. Evaluation of disposition scores in Bos indicus/Bos taurus cross calves at different stages of production. [Internet] [Masters thesis]. Texas A&M University; 2008. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/85987.

Council of Science Editors:

Funkhouser RR. Evaluation of disposition scores in Bos indicus/Bos taurus cross calves at different stages of production. [Masters Thesis]. Texas A&M University; 2008. Available from: http://hdl.handle.net/1969.1/85987

Texas A&M University

26. Gladney, Cody Jack. Evaluation of udder and teat characteristics, calf growth, and reproduction in young Bos indicus-Bos taurus cows.

Degree: MS, Animal Breeding, 2008, Texas A&M University

URL: http://hdl.handle.net/1969.1/85988

► Sire and family effects were evaluated for calf growth, udder and teat conformation, and reproduction traits in 2- to 4- yr-old cows from the McGregor… (more)

Subjects/Keywords: Bos indicus; cow productivity; genetics; udder traits; reproduction

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APA (6^th Edition):

Gladney, C. J. (2008). Evaluation of udder and teat characteristics, calf growth, and reproduction in young Bos indicus-Bos taurus cows. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/85988

Chicago Manual of Style (16^th Edition):

Gladney, Cody Jack. “Evaluation of udder and teat characteristics, calf growth, and reproduction in young Bos indicus-Bos taurus cows.” 2008. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/85988.

MLA Handbook (7^th Edition):

Gladney, Cody Jack. “Evaluation of udder and teat characteristics, calf growth, and reproduction in young Bos indicus-Bos taurus cows.” 2008. Web. 17 Jan 2021.

Vancouver:

Gladney CJ. Evaluation of udder and teat characteristics, calf growth, and reproduction in young Bos indicus-Bos taurus cows. [Internet] [Masters thesis]. Texas A&M University; 2008. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/85988.

Council of Science Editors:

Gladney CJ. Evaluation of udder and teat characteristics, calf growth, and reproduction in young Bos indicus-Bos taurus cows. [Masters Thesis]. Texas A&M University; 2008. Available from: http://hdl.handle.net/1969.1/85988

Texas A&M University

27. Hagen, Darren Erich. Identification and characterization of germline-specific promoters for remobilization of transgenes in the mosquitoes, Aedes aegypti and Anopheles gambiae.

Degree: PhD, Genetics, 2009, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-1513

► The development of genetic transformation systems in insects has revolutionized the field of entomology. Transgenic insects provide tools to identify, isolate and analyze insect genes… (more)

▼ The development of genetic transformation systems in insects has revolutionized the field of entomology. Transgenic insects provide tools to identify, isolate and analyze insect genes and to genetically modify insects for the purposes of insect control or disease vector modification. When transformation frequencies are high, multiple transgenic lines can be generated with relative ease. However, in most mosquito species, the results of transformation experiments have been suboptimal. Increased mosquito transformation efficiency is a research priority. Additionally, incorporation of refractory transgenes will not be sufficient to modify natural populations. A gene drive system will be required to allow transgenes to proliferate throughout populations and potentially reach fixation. This study proposes the use of germline-specific regulatory elements to promote confined, regulated transposase expression within the germ tissue. Creation of helper constructs utilizing endogenous promoters will potentially increase genetic transformation frequencies. The generation of lab strains of mosquitoes expressing an endogenous source of transposase within the germline will also serve as a powerful research tool. Endogenous sources of transposase will allow for comparative analysis of integration rates using different donor plasmids. Finally, the generation of autonomous transposable elements will provide a gene drive mechanism to move a tightly-linked refractory gene into a population. Four genes have been identified, cloned, and characterized, revealing expression patterns expected of germline-specific genes. Transcription profiles and in situ hybridization data support these conclusions. Putative cis-acting regulatory elements have been cloned and incorporated into DNA plasmid constructs. These elements are cloned in a manner such that they will regulate fluorescent gene expression. Additionally, similar elements have been cloned upstream of the Mos1 open reading frame, within the inverted terminal repeats of the mariner transposable element, thus creating autonomous elements and a potential gene drive mechanism. Advisors/Committee Members: Coates, Craig J. (advisor), Elsik, Christine (committee member), Ficht, Thomas (committee member), Gill, Clare (committee member).

Subjects/Keywords: mosquito; germline; transgene

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APA (6^th Edition):

Hagen, D. E. (2009). Identification and characterization of germline-specific promoters for remobilization of transgenes in the mosquitoes, Aedes aegypti and Anopheles gambiae. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1513

Chicago Manual of Style (16^th Edition):

Hagen, Darren Erich. “Identification and characterization of germline-specific promoters for remobilization of transgenes in the mosquitoes, Aedes aegypti and Anopheles gambiae.” 2009. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-1513.

MLA Handbook (7^th Edition):

Hagen, Darren Erich. “Identification and characterization of germline-specific promoters for remobilization of transgenes in the mosquitoes, Aedes aegypti and Anopheles gambiae.” 2009. Web. 17 Jan 2021.

Vancouver:

Hagen DE. Identification and characterization of germline-specific promoters for remobilization of transgenes in the mosquitoes, Aedes aegypti and Anopheles gambiae. [Internet] [Doctoral dissertation]. Texas A&M University; 2009. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1513.

Council of Science Editors:

Hagen DE. Identification and characterization of germline-specific promoters for remobilization of transgenes in the mosquitoes, Aedes aegypti and Anopheles gambiae. [Doctoral Dissertation]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1513

Texas A&M University

28. Garretson, Pamela Donn. Role of P-glycoprotein in Haemonchus contortus anthelmintic resistance.

Degree: MS, Veterinary Parasitology, 2009, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-1633

► The gastrointestinal parasite, Haemonchus contortus, is of major concern in the sheep and goat industry as well as in zoological settings. Over the years this… (more)

Subjects/Keywords: Anthelmintic resistance; Goats; Haemonchus contortus; Haemonchosis; P-glycoprotein; Sheep

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APA (6^th Edition):

Garretson, P. D. (2009). Role of P-glycoprotein in Haemonchus contortus anthelmintic resistance. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1633

Chicago Manual of Style (16^th Edition):

Garretson, Pamela Donn. “Role of P-glycoprotein in Haemonchus contortus anthelmintic resistance.” 2009. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-1633.

MLA Handbook (7^th Edition):

Garretson, Pamela Donn. “Role of P-glycoprotein in Haemonchus contortus anthelmintic resistance.” 2009. Web. 17 Jan 2021.

Vancouver:

Garretson PD. Role of P-glycoprotein in Haemonchus contortus anthelmintic resistance. [Internet] [Masters thesis]. Texas A&M University; 2009. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1633.

Council of Science Editors:

Garretson PD. Role of P-glycoprotein in Haemonchus contortus anthelmintic resistance. [Masters Thesis]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1633

Texas A&M University

29. Amen, Tonya Sue. Birth, weaning, carcass, and meat traits in Bos indicus-Bos taurus reciprocal backcross calves produced through embryo transfer.

Degree: MS, Animal Science, 2005, Texas A&M University

URL: http://hdl.handle.net/1969.1/1335

► Angus - Bos indicus (Brahman or Nellore) reciprocal backcross embryo transfer calves belonging to 28 full-sib families were evaluated for differences in birth weight (BW),… (more)

▼ Angus - Bos indicus (Brahman or Nellore) reciprocal backcross embryo transfer calves belonging to 28 full-sib families were evaluated for differences in birth weight (BW), gestation length (GL), weaning weight (WW), carcass weight (HCW), longissimus muscle area (REA), fat thickness (adjusted (ADJFAT) and actual(ACTFAT)), intramuscular fat (MARB), and Warner-Bratzler shear force tenderness (WBSF). Family types with a greater proportion of Bos indicus in the sire in relation to the amount in the dam (F1 x A and B x F1) averaged longer GL and heavier BW than their respective reciprocal crosses (A x F1 and F1 x B). Calves had longer GL when the F1 parent was BA as opposed to AB. Small differences (statistically insignificant) were detected for BW, but no consistent difference was found between offspring of AB and BA parental types, with the exception of male F1-sired calves. F1 x A and B x F1 crosses also showed a large BW difference between males and females (about 5.0 kg), while A x F1 and F1 x B crosses showed no BW difference between males and females. Further examination within each sex showed a difference between male reciprocals that was two times that of females. Calves with a higher percentage of Bos indicus in the sire compared to the proportion in the dam showed the same trend, as they were still heavier at weaning, and produced heavier carcasses than the reciprocal crosses, though these differences were not significant. As a whole, A backcross calves had more ACTFAT, more ADJFAT, larger REA, more MARB, and lower WBSF than B backcross calves, though no significant differences were detected between reciprocal crosses for any of these traits. These results suggest that for weight related traits, especially BW, both the breed constitution of the calf and the cross that produces the calf play an important role in its ultimate performance for Bos indicus crossbred calves. For carcass and meat related traits, it appears that the breed make-up of the calf itself is more significant in influencing performance than the cross used to produce the calf. Advisors/Committee Members: Herring, Andy (advisor), Gill, Clare (advisor), Dahm, P. Fred (committee member), Sanders, Jim (committee member).

Subjects/Keywords: reciprocal cross; Bos indicus; birth; weaning; carcass; meat

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APA (6^th Edition):

Amen, T. S. (2005). Birth, weaning, carcass, and meat traits in Bos indicus-Bos taurus reciprocal backcross calves produced through embryo transfer. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/1335

Chicago Manual of Style (16^th Edition):

Amen, Tonya Sue. “Birth, weaning, carcass, and meat traits in Bos indicus-Bos taurus reciprocal backcross calves produced through embryo transfer.” 2005. Masters Thesis, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/1335.

MLA Handbook (7^th Edition):

Amen, Tonya Sue. “Birth, weaning, carcass, and meat traits in Bos indicus-Bos taurus reciprocal backcross calves produced through embryo transfer.” 2005. Web. 17 Jan 2021.

Vancouver:

Amen TS. Birth, weaning, carcass, and meat traits in Bos indicus-Bos taurus reciprocal backcross calves produced through embryo transfer. [Internet] [Masters thesis]. Texas A&M University; 2005. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/1335.

Council of Science Editors:

Amen TS. Birth, weaning, carcass, and meat traits in Bos indicus-Bos taurus reciprocal backcross calves produced through embryo transfer. [Masters Thesis]. Texas A&M University; 2005. Available from: http://hdl.handle.net/1969.1/1335

Texas A&M University

30. Nicholson, Kristin Leigh. Meat Quality and Disposition of F2 Nellore x Angus Cross Cattle.

Degree: PhD, Animal Science, 2009, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2869

► Correlations between cattle disposition and meat quality were expected to be found, as well as differences in meat quality traits among contemporary groups, sires, and… (more)

▼ Correlations between cattle disposition and meat quality were expected to be found, as well as differences in meat quality traits among contemporary groups, sires, and families nested within sires. Temperament effects on meat quality were evaluated in Nellore × Angus F2 cross cattle (n = 238) over a 3-yr period, with harvests twice a year. Five aspects of temperament – aggressiveness, nervousness, flightiness, gregariousness, and overall temperament – were evaluated at weaning and yearling ages, as well as an overall temperament score at slaughter. USDA quality grade, fat thickness, adjusted fat thickness, hot carcass weight, USDA yield grade, and chemical fat were correlated negatively (P < 0.05) with weaning temperament scores, aggressiveness, nervousness, flightiness, gregariousness, and overall temperament. No significant correlation was found between Warner-Bratzler shear and weaning temperament traits. USDA quality grade and live weight were correlated negatively (P < 0.05) with yearling temperament scores, nervousness, flightiness, gregariousness, overall temperament score as well as the temperament score observed at slaughter. Fat thickness and adjusted fat thickness also were correlated negatively (P < 0.05) with yearling gregariousness, yearling overall, and slaughter overall temperament. Yearling gregariousness was correlated positively (P < 0.05) with Warner-Bratzler shear from both ES and NON carcasses. Least squares mean differences were evaluated among contemporary groups, sires, and families nested within sires for overall temperament traits and meat quality traits. Contemporary group differences found were thought to be explained by environmental factors, as seen in contemporary group 5, which had the smallest ribeye possibly caused by the shortest feeding period. Steers sired by 297J had the lowest (calmest) temperament scores, most 12th rib fat, highest numerical yield grade, and the heaviest weights. Sire 437J had steers with the highest (wildest) temperament scores, the least fat and lowest numerical yield grade. This population was designed to identify QTL for economically important traits and appears to be useful for this purpose because of the differences found both between and within families. Advisors/Committee Members: Savell, Jeffrey W. (advisor), Gill, Clare A. (committee member), Lineberger, R. Daniel (committee member), Smith, Stephen B. (committee member).

Subjects/Keywords: Meat Quality; Disposition; Temperament; Bos indicus

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APA (6^th Edition):

Nicholson, K. L. (2009). Meat Quality and Disposition of F2 Nellore x Angus Cross Cattle. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2869

Chicago Manual of Style (16^th Edition):

Nicholson, Kristin Leigh. “Meat Quality and Disposition of F2 Nellore x Angus Cross Cattle.” 2009. Doctoral Dissertation, Texas A&M University. Accessed January 17, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2869.

MLA Handbook (7^th Edition):

Nicholson, Kristin Leigh. “Meat Quality and Disposition of F2 Nellore x Angus Cross Cattle.” 2009. Web. 17 Jan 2021.

Vancouver:

Nicholson KL. Meat Quality and Disposition of F2 Nellore x Angus Cross Cattle. [Internet] [Doctoral dissertation]. Texas A&M University; 2009. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2869.

Council of Science Editors:

Nicholson KL. Meat Quality and Disposition of F2 Nellore x Angus Cross Cattle. [Doctoral Dissertation]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2869

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