Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

You searched for +publisher:"Texas A&M University" +contributor:("Fajt, Virginia R."). Showing records 1 – 2 of 2 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


Texas A&M University

1. Padgett, Ashley Loren. Comparison of Transdermal Fentanyl and Intramuscularly Administered Buprenorphine for Postoperative Pain in Pregnant Sheep.

Degree: MS, Biomedical Sciences, 2018, Texas A&M University

Designing perioperative analgesic regimen for ruminants is problematic as pain assessment is difficult and pregnancy adds additional considerations. The aim of this study was to assess the nociceptive properties of intramuscularly administered buprenorphine and transdermally administered fentanyl utilizing a composite pain score system. To better confirm that the observed abnormal behavior was related to pain, the current study attempted to characterize the nociceptive properties of the analgesic agents at a given plasma drug concentration, which has not previously been done. Additionally, the study characterized transplacental movement of analgesic agents via fetal plasma drug concentrations. In this study, we compared intramuscularly administered buprenorphine at a dose of 0.01 mg/kg every 8 hours for 48 hours starting at induction for surgery (n=6) to transdermal fentanyl patches (n=6) applied in the dorsal thorax region 24 hours before surgery at a dose of 2μg/kg/hr for postoperative pain. Ewe blood samples were collected and signs of pain and sedation were measured 24 hours before surgery (time -24), induction to surgery (time 0), and 2, 4, 6, 8, 12, 24, 36, 48 hours after. Using an indwelling fetal arterial catheter that was placed during the surgery, fetal blood pressure was recorded and blood samples were collected. Drug concentrations were measured in maternal and fetal plasma and amniotic fluid. The buprenorphine treated ewes exhibited more pain consistent behaviors than those treated with fentanyl, and their postoperative pain scores were significantly higher than the preoperative value. There were also significant differences in cardiovascular variables from the anesthesia records between the two groups. Overall, transdermal administration of fentanyl provided adequate analgesia with little adverse effects, making it a candidate for optimal postoperative pain management in sheep. Advisors/Committee Members: Washburn, Shannon E (advisor), Lepiz, Mauricio L (committee member), Fajt, Virginia R (committee member), Patterson, Carly (committee member).

Subjects/Keywords: transdermal fentanyl; opioids; pregnant sheep; buprenorphine; analgesia; anesthesia

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Padgett, A. L. (2018). Comparison of Transdermal Fentanyl and Intramuscularly Administered Buprenorphine for Postoperative Pain in Pregnant Sheep. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/174041

Chicago Manual of Style (16th Edition):

Padgett, Ashley Loren. “Comparison of Transdermal Fentanyl and Intramuscularly Administered Buprenorphine for Postoperative Pain in Pregnant Sheep.” 2018. Masters Thesis, Texas A&M University. Accessed December 01, 2020. http://hdl.handle.net/1969.1/174041.

MLA Handbook (7th Edition):

Padgett, Ashley Loren. “Comparison of Transdermal Fentanyl and Intramuscularly Administered Buprenorphine for Postoperative Pain in Pregnant Sheep.” 2018. Web. 01 Dec 2020.

Vancouver:

Padgett AL. Comparison of Transdermal Fentanyl and Intramuscularly Administered Buprenorphine for Postoperative Pain in Pregnant Sheep. [Internet] [Masters thesis]. Texas A&M University; 2018. [cited 2020 Dec 01]. Available from: http://hdl.handle.net/1969.1/174041.

Council of Science Editors:

Padgett AL. Comparison of Transdermal Fentanyl and Intramuscularly Administered Buprenorphine for Postoperative Pain in Pregnant Sheep. [Masters Thesis]. Texas A&M University; 2018. Available from: http://hdl.handle.net/1969.1/174041

2. Rollo, Susan Noble. Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin.

Degree: PhD, Biomedical Sciences, 2012, Texas A&M University

The purpose of this dissertation is threefold: to determine the differences in apparent prevalence and the antimicrobial susceptibility of Campylobacter spp. between antimicrobial-free and conventional swine farms; secondly, to introduce an appropriate statistical model to compare the minimum inhibitory concentration distributions of Escherichia coli and Campylobacter spp. isolated from both farm types; and thirdly, to examine the potential herd level risk factors that may be associated with antimicrobial resistance of Campylobacter spp. and E. coli isolates from finishers on antimicrobial-free and conventional farming systems. In addition, a critical review of studies that have compared the levels and patterns of antimicrobial resistance among animals from antimicrobial-free and conventional farming practices was performed. Fecal samples from 15 pigs were collected from each of 35 antimicrobial-free and 60 conventional farms in the Midwestern U.S. Campylobacter spp. was isolated from 464 of 1,422 fecal samples, and each isolate was tested for susceptibility to 6 antimicrobials. The apparent prevalence of Campylobacter spp. isolates was approximately 33 percent on both conventional and antimicrobial-free farms. The proportion of antimicrobial resistance among Campylobacter was higher for three antimicrobials within conventional compared to antimicrobial-free farms. The susceptibilities of populations of bacteria to antimicrobial drugs were summarized as minimum inhibitory concentration (MIC) frequency distributions. The use of MIC values removed the subjectivity associated with the choice of breakpoints which define an isolate as susceptible or resistant. A discrete-time survival analysis model was introduced as the recommended statistical model when MICs are the outcome. A questionnaire was completed by each farm manager on biosecurity, preventive medication, vaccines, disease history, and production management. Multivariable population-averaged statistical models were used to determine the relationships among antimicrobial susceptibility patterns and potential herd-level risk factors. Controlling for herd type (antimicrobial-free versus conventional), each antimicrobial-bacterial species combination yielded unique combinations of risk factors; however, housing type, history of rhinitis, farm ventilation, and history of swine flu were significant in more than one model. A variety of herd-level practices were associated with the prevalence of antimicrobial resistance on swine farms. Further studies are encouraged when considering interventions for antimicrobial resistance on both antimicrobial-free and conventional farms. Advisors/Committee Members: Norby, Bo (advisor), Scott, H M. (committee member), Fajt, Virginia R. (committee member), Huber, John C. (committee member), Libal, Melissa (committee member).

Subjects/Keywords: antimicrobial resistance; minimum inhibitory concentration; discrete time survival analysis; antimicrobial-free farms; Escherichia coli; Campylobacter; risk factors; swine

Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Rollo, S. N. (2012). Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9755

Chicago Manual of Style (16th Edition):

Rollo, Susan Noble. “Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin.” 2012. Doctoral Dissertation, Texas A&M University. Accessed December 01, 2020. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9755.

MLA Handbook (7th Edition):

Rollo, Susan Noble. “Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin.” 2012. Web. 01 Dec 2020.

Vancouver:

Rollo SN. Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin. [Internet] [Doctoral dissertation]. Texas A&M University; 2012. [cited 2020 Dec 01]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9755.

Council of Science Editors:

Rollo SN. Herd-level Risk Factors Associated with Antimicrobial Susceptibility Patterns and Distributions in Fecal Bacteria of Porcine Origin. [Doctoral Dissertation]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9755

.