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You searched for +publisher:"Shri Jagdishprasad Jhabarmal Tibarewala University" +contributor:("Patel, Vishnu Motilal"). Showing records 1 – 2 of 2 total matches.

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1. Patel, Tarunkumar Kiritbhai. Formulation and evaluation of drug delivery systems for the treatment of periodontitis.

Degree: Pharmaceutical Sciences, 2013, Shri Jagdishprasad Jhabarmal Tibarewala University

For the effective treatment of periodontitis, a prolonged drug release at the infected pocket is essential. Medicated dental pastes and gels for the extended period of retention in infected cavity were prepared for improved local action. Ciprofloxacin hydrochloride and Ofloxacin was used as model drug. Medicated dental pastes were prepared using release retardant mucoadhesive polymer like Methylcellulose, Hydroxy propyl methylcellulose, Hydroxy ethyl cellulose, Hydroxy propyl cellulose and Sodium carboxy methylcellulose, whereas medicated dental gels were prepared with different mucoadhesive polymer like Methylcellulose, Hydroxy propyl methylcellulose, Hydroxy ethyl cellulose, Hydroxy propyl cellulose and Sodium carboxy methylcellulose in different concentrations of propylene glycol. The prepared formulations were subjected for various physicochemical studies like pH, spreadability, extrudability, viscosity, drug content, in vitro drug release, rheological studies, DSC, FTIR and stability studies. In vitro drug release studies were carried out in diffusion cell using pH 7.2 phosphates buffer as receptor medium. In vitro drug release studies exhibited extended release of drug over a period of 6 hrs and release was depended on the type of polymer used. DSC and FTIR studies indicate that there was no interaction between drug-polymer and drug-other additives. During rheological studies a wider range of shear rate values was studied to establish the paste and gels nature. Plots of shear rate versus shear stress shown that all the formulations were non-Newtonian and exhibit pseudoplastic behavior. Optimal formulations were selected for stability studies. During stability studies different parameters like pH, spreadability, extrudability, viscosity and drug content, did not show any significant (pgt0.05) variation. In conclusion, hydrocolloid based medicated dental pastes and gels appear to be potential in controlling the release of medicament. newlineKey words: hydrochloride, Ofloxacin, Medicated dental pastes

Summary p. 98–99, References p. 100-110

Advisors/Committee Members: Patel, Vishnu Motilal.

Subjects/Keywords: Pharmaceutical Sciences; Drug delivery systems

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Patel, T. K. (2013). Formulation and evaluation of drug delivery systems for the treatment of periodontitis. (Thesis). Shri Jagdishprasad Jhabarmal Tibarewala University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/13929

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Patel, Tarunkumar Kiritbhai. “Formulation and evaluation of drug delivery systems for the treatment of periodontitis.” 2013. Thesis, Shri Jagdishprasad Jhabarmal Tibarewala University. Accessed March 21, 2019. http://shodhganga.inflibnet.ac.in/handle/10603/13929.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Patel, Tarunkumar Kiritbhai. “Formulation and evaluation of drug delivery systems for the treatment of periodontitis.” 2013. Web. 21 Mar 2019.

Vancouver:

Patel TK. Formulation and evaluation of drug delivery systems for the treatment of periodontitis. [Internet] [Thesis]. Shri Jagdishprasad Jhabarmal Tibarewala University; 2013. [cited 2019 Mar 21]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/13929.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Patel TK. Formulation and evaluation of drug delivery systems for the treatment of periodontitis. [Thesis]. Shri Jagdishprasad Jhabarmal Tibarewala University; 2013. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/13929

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Mansuri, Mushirbhai Inayatbhai. Evaluation of antidiabetic and antihyperlipidemic activity of euphorbia neriifolia linn. in animal models.

Degree: Pharmacutical Sciences, 2014, Shri Jagdishprasad Jhabarmal Tibarewala University

Euphorbia neriifolia Linn. (Euphorbiaceae) is traditionally used to treat diabetes mellitus.The extract of Euphorbia neriifolia Linn. are having potential in the development of drug for diabetes due to their antidiabetic activity. Purpose of the study was to evaluate the antidiabetic antihyperlipidemic activity of ethanolic extracts of leaves of Euphorbia neriifolia Linn. (Euphorbiaceae). The present study was undertaken to evaluate the antidiabetic and antihyperlipidemic effect in streptozotocin-nicotinamide and high fat diet-streptozotocin (HFD-STZ) induced type-2 diabetic rats. Albino rats weighing 150-200 gm and Sprague Dawley rats weighing 200-250 gm. Experimental diabetes in streptozotocin-nicotinamide was induced by a single intraperitonial injection of streptozotocin (60 mg/kg), 15 minutes after the i.p. administration of 120mg/kg nicotinamide and in HFD-STZ, two weeks of HFD rats were given with intraperitonial injection of streptozotocin (STZ) (35mg/kg body weight). The purpose of this study was to examine the effect of repeated oral administration of the ethanolic extract of Euphorbia neriifolia Linn at a dose of (200 and 400 mg/kg) on body weight, fasting blood glucose levels, lipid metabolism, insulin, liver glycogen and glycated heamoglobin in type-2 diabetic rats. After 15 days in STZ-nicotinamide and 21 days in HFD-STZ, repeated oral administration of 400mg and 200mg/kg of Euphorbia neriifolia ethanolic extract (ENEE) produced a significant decrease on body weight, fasting blood glucose, triglyceride, total cholesterol, LDL, VLDL and glycated heamoglobin in HFD-STZ and STZ-nicotinamide type-2 diabetic rats, on the other hand there was significant increase in HDL levels and liver glycogen. Serum insulin was decreased and increased in STZ-nicotinamide and HFD-STZ diabetic rats and was improved by treatment of ENEE. Glibenclamide 2.5mg/kg,p.o was used as standard drug.In oral glucose tolerance test, reduction of fasting blood glucose levels took place from 60 min of extract administration in

References p. 149-167, Annexure p. 168-169

Advisors/Committee Members: Patel, Vishnu Motilal.

Subjects/Keywords: Pharmacutical Sciences

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Mansuri, M. I. (2014). Evaluation of antidiabetic and antihyperlipidemic activity of euphorbia neriifolia linn. in animal models. (Thesis). Shri Jagdishprasad Jhabarmal Tibarewala University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/14582

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Mansuri, Mushirbhai Inayatbhai. “Evaluation of antidiabetic and antihyperlipidemic activity of euphorbia neriifolia linn. in animal models.” 2014. Thesis, Shri Jagdishprasad Jhabarmal Tibarewala University. Accessed March 21, 2019. http://shodhganga.inflibnet.ac.in/handle/10603/14582.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Mansuri, Mushirbhai Inayatbhai. “Evaluation of antidiabetic and antihyperlipidemic activity of euphorbia neriifolia linn. in animal models.” 2014. Web. 21 Mar 2019.

Vancouver:

Mansuri MI. Evaluation of antidiabetic and antihyperlipidemic activity of euphorbia neriifolia linn. in animal models. [Internet] [Thesis]. Shri Jagdishprasad Jhabarmal Tibarewala University; 2014. [cited 2019 Mar 21]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/14582.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mansuri MI. Evaluation of antidiabetic and antihyperlipidemic activity of euphorbia neriifolia linn. in animal models. [Thesis]. Shri Jagdishprasad Jhabarmal Tibarewala University; 2014. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/14582

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.