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Penn State University
1.
Hill, Nikki Lynn.
Personality as a Moderator of Cognitive Stimulation Outcomes in Older Adults at High Risk for Cognitive Decline.
Degree: 2013, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/18692
► Background: Individuals with dementia and delirium experience an accelerated period of cognitive decline which is often unresolved, leading to long-term negative consequences. Interventions targeting acute…
(more)
▼ Background: Individuals with dementia and delirium experience an accelerated period of cognitive decline which is often unresolved, leading to long-term negative consequences. Interventions targeting acute cognitive decline in this population are largely unexplored, and moderators of intervention effectiveness have yet to be determined.
Purpose: The purpose of this study was to determine whether personality moderated cognition-focused intervention outcomes in individuals at high risk for cognitive decline: those with dementia and delirium.
Methods: This study utilized a portion (n=71) of the sample participating in a randomized repeated measures clinical trial, Recreational Stimulation for Elders as a Vehicle to Resolve Delirium Superimposed on Dementia (RESERVE-DSD). Subjects with dementia and concurrent delirium were recruited upon admission to one of seven Pennsylvania nursing homes with post-acute services for rehabilitation following hospitalization; all diagnoses were adjudicated by an expert panel. The control group received routine nursing care and prescribed therapies as typically delivered for their particular health condition. In addition to usual care, subjects randomized to the treatment group received 30 minutes of cognitive stimulation daily for up to 30 days. The intervention consisted of personally tailored, mentally challenging recreational activities that incrementally increased in difficulty. Baseline measures included demographic characteristics, ApoE ε4 status, Lifetime of Experiences Questionnaire, the Modified Blessed Dementia Rating Scale, and the NEO™ Personality Inventory-3. Measures of delirium, attention, orientation, memory, and executive function were taken daily for both groups. Engagement in the intervention was measured by the time spent on task (up to 30 minutes) as well as the level of participation. Linear mixed-effects models were used to examine the moderating effects of the five personality traits on the four cognitive outcomes, as well as main effects on engagement outcomes among the treatment group.
Results: Significant moderating effects of personality traits were found with regard to two cognitive outcomes: agreeableness moderated the memory outcome and extraversion moderated the executive function outcome. Individuals with higher agreeableness were more likely to have improved memory outcomes, and those with lower extraversion more likely to have improved executive function outcomes, as a result of the cognition-focused intervention. Lower openness, higher agreeableness, and lower conscientiousness were associated with greater engagement in the intervention.
Conclusion: Personality traits are known to influence a wide variety of health and treatment outcomes, and their role in cognition-focused interventions for individuals with dementia and delirium is in line with these findings. The consideration of personality in further development and testing of these interventions will provide for clarification and characterization of these effects.
Advisors/Committee Members: Ann Marie Kolanowski, Committee Chair/Co-Chair, Donna Marie Fick, Committee Member, Vernon Michael Chinchilli, Committee Member, Rita Jablonski, Committee Member.
Subjects/Keywords: dementia; delirium; personality; moderators; cognitive interventions
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APA (6th Edition):
Hill, N. L. (2013). Personality as a Moderator of Cognitive Stimulation Outcomes in Older Adults at High Risk for Cognitive Decline. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/18692
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hill, Nikki Lynn. “Personality as a Moderator of Cognitive Stimulation Outcomes in Older Adults at High Risk for Cognitive Decline.” 2013. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/18692.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hill, Nikki Lynn. “Personality as a Moderator of Cognitive Stimulation Outcomes in Older Adults at High Risk for Cognitive Decline.” 2013. Web. 22 Jan 2021.
Vancouver:
Hill NL. Personality as a Moderator of Cognitive Stimulation Outcomes in Older Adults at High Risk for Cognitive Decline. [Internet] [Thesis]. Penn State University; 2013. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/18692.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hill NL. Personality as a Moderator of Cognitive Stimulation Outcomes in Older Adults at High Risk for Cognitive Decline. [Thesis]. Penn State University; 2013. Available from: https://submit-etda.libraries.psu.edu/catalog/18692
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
2.
Yevchak, Andrea Marie.
Informal Caregiver Detection, Recognition, and Reporting of Symptoms of Delirium in Hospital Older Adults with Dementia.
Degree: 2013, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/18874
► Background: Delirium is common, costly, and leads to adverse consequences in hospitalized older adults. Pre-existing dementia is the most common risk factor for the development…
(more)
▼ Background: Delirium is common, costly, and leads to adverse consequences in hospitalized older adults. Pre-existing dementia is the most common risk factor for the development of delirium. Despite multidimensional interventions aimed at improving outcomes, delirium superimposed on dementia remains poorly detected and recognized by formal healthcare providers. Informal caregivers are proposed as a viable solution to improve detection and recognition in this vulnerable population.
Purpose: The purpose of this study is to systematically assess informal caregiver recognition, detection, and reporting of symptoms of delirium in hospitalized older adults with pre-existing dementia.
Methods: Quantitative and qualitative data were collected in this descriptive, exploratory work from 38 informal caregiver and patient dyads. This study was embedded within a National Institutes of Nursing Research funded cluster, randomized controlled clinical trial, Early Nurse Detection of Delirium Superimposed on Dementia (END-DSD). In addition to data collected within this study, an additional informal caregiver post-hospitalization telephone interview was conducted (N=23).
Results: Although there was poor agreement between researcher and informal caregiver ratings of full and subsyndromal delirium, there was 100% agreement on delirium features of acute change and inattention. These are two hallmark features of delirium. Results from the qualitative data explore the acute care experience for informal caregivers of persons with pre-existing dementia and suggest that delirium occurs and persists across transitions of care.
Conclusion: Informal caregivers appear to be a source of information in the acute care setting to improve detection and recognition of delirium superimposed on dementia. This group needs to be considered in research and practice as a critical component of the transdisciplinary healthcare team.
Advisors/Committee Members: Donna Marie Fick, Dissertation Advisor/Co-Advisor, Ann Marie Kolanowski, Committee Member, Steven Howard Zarit, Committee Member, Vernon Michael Chinchilli, Committee Member.
Subjects/Keywords: Dementia; Delirium; Informal Caregivers; Acute Care; Hospital
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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Manager
APA (6th Edition):
Yevchak, A. M. (2013). Informal Caregiver Detection, Recognition, and Reporting of Symptoms of Delirium in Hospital Older Adults with Dementia. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/18874
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yevchak, Andrea Marie. “Informal Caregiver Detection, Recognition, and Reporting of Symptoms of Delirium in Hospital Older Adults with Dementia.” 2013. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/18874.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yevchak, Andrea Marie. “Informal Caregiver Detection, Recognition, and Reporting of Symptoms of Delirium in Hospital Older Adults with Dementia.” 2013. Web. 22 Jan 2021.
Vancouver:
Yevchak AM. Informal Caregiver Detection, Recognition, and Reporting of Symptoms of Delirium in Hospital Older Adults with Dementia. [Internet] [Thesis]. Penn State University; 2013. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/18874.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yevchak AM. Informal Caregiver Detection, Recognition, and Reporting of Symptoms of Delirium in Hospital Older Adults with Dementia. [Thesis]. Penn State University; 2013. Available from: https://submit-etda.libraries.psu.edu/catalog/18874
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
3.
Liu, Jingyuan.
Statistical Methods for Different Ultrahigh Dimensional Models.
Degree: 2013, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/16595
► This thesis studies feature screening and variable selection procedures for ultrahigh dimensional varying coefficient models and partially linear models, and the extension of the methods…
(more)
▼ This thesis studies feature screening and variable selection procedures for ultrahigh
dimensional varying coefficient models and partially linear models, and the
extension of the methods to longitudinal data structure.
A new independence screening procedure is proposed for varying coefficient
models based on the conditional correlation between each predictor and the response
given the depending covariate (CCIS, for short). We establish and prove
the ranking consistency and sure screening property of CCIS, and demonstrate
them empirically through simulations. Furthermore, the iterative screening procedure
(ICCIS) is developed to enhance the finite sample performance. In the
Framingham Heart Study (FHS) example, we derive a new two-stage approach to
select significant Single-nucleotide polymorphism (SNPs) for explaining body mass
index (BMI), and the effect of SNPs may depend on the baseline age of patients.
Firstly CCIS is applied to reduce the ultrahigh dimensionality to the scale under
sample size, and secondly several penalized regression techniques are modified for
varying coefficient models to further select important variables as well as estimate
the coefficient functions.
Moreover, CCIS for varying coefficient models can be extended for the longitudinal
data structure. Consider the time-varying coefficient model as an example,
where multiple response values are observed for every subject. We apply CCIS
in the first stage to the pooled sample, in which we treat all the observations as
independent individuals, although those from the same subject are actually correlated.
In this case, the within subject correlation is ignored in the screening stage.
However, the simulation studies show that we do not lose ranking consistency and
sure screening property by doing this. In the real data example, we use a modified
two-stage approach to restudy the effect of SNPs on BMI using FHS data. The
dynamic pattern of age instead of baseline age is considered to illustrate the longitudinal
structure. If the efficiency of coefficient function estimators are of interest,
we can add one more step of a weighted least squared method after the variable
selection stage, by incorporating the covariance matrix estimation procedure.
For partially linear models, another independence screening procedure is developed
in this thesis based on the partial residual method (PRSIS, for short). The
partially linear model can be converted to a linear model with transformed response
and predictors, and then the traditional screening methods for linear models can
be applied, such as sure independence screening (SIS, Fan and Lv, 2008). The desired
theoretical properties are demonstrated through simulation studies. Soybean
data analysis are provided to illustrate the two-stage approach based on PRSIS,
using which the important markers are selected for explaining the dry biomass of
soybean.
Advisors/Committee Members: Runze Li, Dissertation Advisor/Co-Advisor, Rongling Wu, Committee Chair/Co-Chair, Vernon Michael Chinchilli, Committee Member, Dennis Kon Jin Lin, Committee Member, Liwang Cui, Special Member.
Subjects/Keywords: ultrahigh dimension; varying coefficient model; partially linear model; feature screening
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Liu, J. (2013). Statistical Methods for Different Ultrahigh Dimensional Models. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/16595
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Liu, Jingyuan. “Statistical Methods for Different Ultrahigh Dimensional Models.” 2013. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/16595.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Liu, Jingyuan. “Statistical Methods for Different Ultrahigh Dimensional Models.” 2013. Web. 22 Jan 2021.
Vancouver:
Liu J. Statistical Methods for Different Ultrahigh Dimensional Models. [Internet] [Thesis]. Penn State University; 2013. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/16595.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Liu J. Statistical Methods for Different Ultrahigh Dimensional Models. [Thesis]. Penn State University; 2013. Available from: https://submit-etda.libraries.psu.edu/catalog/16595
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
4.
Pinto, Casey.
Rural Adolescents and Young Adults: Chlamydia and Gonorrhea Acquisition.
Degree: 2016, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/28842
► Background: Risky sexual behavior is a burgeoning topic in the adolescent and young adult literature, particularly with respect to acquisition of sexually transmitted diseases (STDs).…
(more)
▼ Background: Risky sexual behavior is a burgeoning topic in the adolescent and young adult literature, particularly with respect to acquisition of sexually transmitted diseases (STDs). Adolescents and young adults (15-24 years) in the United States have the highest incidence of STDs compared to all other age groups and have been the focus of many preventative measures. However, the focus is on urban populations, thus rural adolescents and young adults remain understudied in the area of risky sexual behavior and STDs.
Purpose: The following dissertation is an ecological descriptive study analyzing chlamydia and gonorrhea rates among both rural adolescent (15-19 years) and rural young adult (20-24 years) populations as compared to urban adolescent and young adult populations.
Methods: The subsequent study utilized three datasets; the Pennsylvania National Electronic Database Surveillance System (PA-NEDSS), census statistics, and the Pennsylvania Center for Education Statistics National School Lunch Program dataset. This dissertation had two main aims. The first aim provided an overview of current Pennsylvania adolescent and young adult chlamydia and gonorrhea rates, both rural and urban, using negative binomial regressions. The second aim provided an analysis of county level data, both rural and urban, over time using a repeated measures analysis to determine change in the rates of chlamydia and gonorrhea over an 11-year period.
Results: This study demonstrated that rates of chlamydia were higher in rural 18-19, 20, and 21-year-old populations for the years 2011 through 2014 as compared to urban populations in Pennsylvania when controlling for poverty and gender. The second outcome demonstrated that among all age groups studied, a significant increase of chlamydia and gonorrhea rates for both males and females were seen in selected counties of PA. While the increase was noted, select counties in both rural and urban settings also had decreases in STD rates.
Conclusions: This dissertation provided empirical evidence that STD rates, specifically chlamydia and gonorrhea, are not only higher in rural areas, but have also increased from 2004 until 2014. The results of this study document the need for further research to better understand the societal and behavioral mechanisms of disease acquisition, with special emphasis on primary prevention methods, in particular in rural areas of Pennsylvania in these young age groups.
Advisors/Committee Members: Lorah D Dorn, Dissertation Advisor/Co-Advisor, Lorah D Dorn, Committee Chair/Co-Chair, Susan Jayne Loeb, Committee Member, Vernon Michael Chinchilli, Committee Member, Ping Du, Committee Member.
Subjects/Keywords: Adolescents; Young Adults; Chlamydia; Gonorrhea; STD
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pinto, C. (2016). Rural Adolescents and Young Adults: Chlamydia and Gonorrhea Acquisition. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/28842
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pinto, Casey. “Rural Adolescents and Young Adults: Chlamydia and Gonorrhea Acquisition.” 2016. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/28842.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pinto, Casey. “Rural Adolescents and Young Adults: Chlamydia and Gonorrhea Acquisition.” 2016. Web. 22 Jan 2021.
Vancouver:
Pinto C. Rural Adolescents and Young Adults: Chlamydia and Gonorrhea Acquisition. [Internet] [Thesis]. Penn State University; 2016. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/28842.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pinto C. Rural Adolescents and Young Adults: Chlamydia and Gonorrhea Acquisition. [Thesis]. Penn State University; 2016. Available from: https://submit-etda.libraries.psu.edu/catalog/28842
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
5.
Fu, Guifang.
Statistical Models for Mapping Genes that Contribute to Shape Variation.
Degree: 2012, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/15374
► Living things come in all shapes and sizes, from bacteria, plants, and animals to humans. Knowledge about the genetic mechanisms for biological shape has far-reaching…
(more)
▼ Living things come in all shapes and sizes, from bacteria, plants, and animals to humans. Knowledge about the genetic mechanisms for biological shape has far-reaching implications for a range of spectrum of scientific disciplines including anthropology, agriculture, developmental biology, evolution and biomedicine. Despite the fundamental importance of morphological shape, the difficulty in quantifying the shape and modeling the ultra-high dimension of the image data make the task of genetic mapping on it increasingly difficult.
In this dissertation, we derived several statistical models for mapping specific genes or quantitative trait loci (QTLs) that govern the variation of morphological shape. We are pioneer in the functional shape genetics area and able to detect several significant genes that control the static allometry of the leaf shape traits by incorporating image analysis, statistical model and marker-based linkage disequilibrium (LD) analysis.
After quantifying the morphological shapes numerically through RCC (Radius Centroid Contour) skills, each phenotype, as a datum, is in the form of samples of functional curves or trajectories with high dimension. In the first model, we decreased the dimension by PCA and illustrated the shape variation piece by piece. In the second model, we developed a nonparametric method to model the mean curve by GEE (Generalized Estimating Equation) local polynomial kernel and model the covariance matrix by functional PCA (Principal Component Analysis. Through functional PCA, we characterized the dominant modes of variation around the overall mean trend function and avoided facing directly the extremely huge dimensional covariance matrix. The models are formulated within the mixture framework, in which different types of shape are thought to result from genotypic discrepancies at a QTL. The EM algorithm was implemented to estimate QTL genotype-specific shapes based on a shape correspondence analysis.
Through incorporating these procedures into the LD based mapping framework, our model led to the detection of several individual significant QTLs responsible for global and local shape variability, addressed many questions in the genetic control of biological shape, and simultaneously estimated QTL allele frequency and marker-QTL linkage disequilibrium. The statistical behavior of the model and its utilization were verified by both real data analysis on the leaf data from China, and computer simulated data.
Advisors/Committee Members: Rongling Wu, Dissertation Advisor/Co-Advisor, Dr Runze Li, Dissertation Advisor/Co-Advisor, Vernon Michael Chinchilli, Committee Member, Dr Jia Li, Committee Member, Qiang Du, Committee Member.
Subjects/Keywords: QTL; Statistical Genetics; Shape Analysis; Plant; Functional Data Analysis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Fu, G. (2012). Statistical Models for Mapping Genes that Contribute to Shape Variation. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/15374
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Fu, Guifang. “Statistical Models for Mapping Genes that Contribute to Shape Variation.” 2012. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/15374.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Fu, Guifang. “Statistical Models for Mapping Genes that Contribute to Shape Variation.” 2012. Web. 22 Jan 2021.
Vancouver:
Fu G. Statistical Models for Mapping Genes that Contribute to Shape Variation. [Internet] [Thesis]. Penn State University; 2012. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/15374.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Fu G. Statistical Models for Mapping Genes that Contribute to Shape Variation. [Thesis]. Penn State University; 2012. Available from: https://submit-etda.libraries.psu.edu/catalog/15374
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
6.
Das, Kiranmoy.
SEMI-PARAMETRIC BAYESIAN FUNCTIONAL MAPPING WITH IRREGULAR SPARSE LONGITUDINAL DATA.
Degree: 2011, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/12109
► Genome-wide Association Studies, popularly known as GWAS, are playing a key role in understanding the genetic patterns of various traits and diseases. Despite the potential…
(more)
▼ Genome-wide Association Studies, popularly known as GWAS, are playing a key role in understanding the genetic patterns of various traits and diseases. Despite the potential importance of GWAS, several limitations of such studies have been recognized in recent years. While most of the genetic traits and diseases are dynamic,
most GWAS consider a single time point phenotypic measurement which results in reduced statistical power and practical usefulness. In this thesis, we have incorporated the functional aspect of the dynamic traits by considering repeated
measurements over subject-specific time points. For that, we have developed semiparametric
approach for joint modelling of the genotype-specific mean trajectories and the covariance matrix. Since for most of the biomedical experiments, it is of interest at what time point a particular event (death of a patient, for example) occurs, we also develop a framework for joint modelling of the longitudinal and survival data. Semi-parametric approach for joint modelling of the mean and covariance function for bivariate longitudinal trait has been proposed here too. All
our proposed approaches have been validated by real data as well as extensive simulation studies.
Advisors/Committee Members: Rongling Wu, Dissertation Advisor/Co-Advisor, Rongling Wu, Committee Chair/Co-Chair, Runze Li, Committee Chair/Co-Chair, Vernon Michael Chinchilli, Committee Member, Debashis Ghosh, Committee Member, Peter Cm Molenaar, Committee Member.
Subjects/Keywords: Longitudinal data; functional mapping; MCMC
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Das, K. (2011). SEMI-PARAMETRIC BAYESIAN FUNCTIONAL MAPPING WITH IRREGULAR SPARSE LONGITUDINAL DATA. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/12109
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Das, Kiranmoy. “SEMI-PARAMETRIC BAYESIAN FUNCTIONAL MAPPING WITH IRREGULAR SPARSE LONGITUDINAL DATA.” 2011. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/12109.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Das, Kiranmoy. “SEMI-PARAMETRIC BAYESIAN FUNCTIONAL MAPPING WITH IRREGULAR SPARSE LONGITUDINAL DATA.” 2011. Web. 22 Jan 2021.
Vancouver:
Das K. SEMI-PARAMETRIC BAYESIAN FUNCTIONAL MAPPING WITH IRREGULAR SPARSE LONGITUDINAL DATA. [Internet] [Thesis]. Penn State University; 2011. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/12109.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Das K. SEMI-PARAMETRIC BAYESIAN FUNCTIONAL MAPPING WITH IRREGULAR SPARSE LONGITUDINAL DATA. [Thesis]. Penn State University; 2011. Available from: https://submit-etda.libraries.psu.edu/catalog/12109
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
7.
Yoo, Mina.
MEASURES OF AGREEMENT IN METHOD COMPARISON STUDIES FOR INTENSIVE LONGITUDINAL DATA
.
Degree: 2011, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/12131
► This dissertation is concerned with assessment of measurement agreement for intensive longitudinal data. Assessment of the measurement agreement encompasses a variety of applications. A number…
(more)
▼ This dissertation is concerned with assessment of measurement agreement for intensive longitudinal data. Assessment of the measurement agreement encompasses a variety of applications. A number of indices for measuring agreement have been developed. However, these measures make a major assumption: that the mean and variation are stable over time. With recent developments in data collection methods and statistical models, intensive longitudinal studies and the analysis of intensive longitudinal data are gaining popularity across many areas. Intensive longitudinal data enable researchers to examine more detailed features of how pro- cesses change over time.
Due to its high intensity of assessments within subjects, it has different characteristics from traditional longitudinal data, which often involve a small number of repeated observations across many individuals. The overall mean of intensive longitudinal data is typically a smooth curve of time and variance of the error process may be time-varying over study duration. Moreover, heterogeneity of intra subject processes such as autocorrelation and instability exists. To overcome these challenges and provide accuracy estimates, we first propose a novel estimation procedure for functional mixed models and partially linear mixed models and study the asymptotic properties of the proposed estimation procedure. Then, we develop a new index of the agreement for intensive longitudinal data, the functional type of concordance correlation coefficient based on proposed models. The functional concordance correlation coefficient is robust with respect to model specification, compared with the popular index, the unified approach of concordance correlation coefficient. The proposed index improves the accuracy of measurement agreement by separating the time trend of measurements from the degree of agreement. All the proposed procedures are assessed by intensive finite sample simulation studies and most are illustrated with real data examples.
Advisors/Committee Members: Dr Runze Li, Dissertation Advisor/Co-Advisor, Runze Li, Committee Chair/Co-Chair, Mosuk Chow, Committee Chair/Co-Chair, Naomi S Altman, Committee Member, Vernon Michael Chinchilli, Committee Member.
Subjects/Keywords: concordance correlation coefficient; varying coefficient models; partially linear models; mixed effects models; measurement agreement; intensive longitudinal data
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yoo, M. (2011). MEASURES OF AGREEMENT IN METHOD COMPARISON STUDIES FOR INTENSIVE LONGITUDINAL DATA
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/12131
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yoo, Mina. “MEASURES OF AGREEMENT IN METHOD COMPARISON STUDIES FOR INTENSIVE LONGITUDINAL DATA
.” 2011. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/12131.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yoo, Mina. “MEASURES OF AGREEMENT IN METHOD COMPARISON STUDIES FOR INTENSIVE LONGITUDINAL DATA
.” 2011. Web. 22 Jan 2021.
Vancouver:
Yoo M. MEASURES OF AGREEMENT IN METHOD COMPARISON STUDIES FOR INTENSIVE LONGITUDINAL DATA
. [Internet] [Thesis]. Penn State University; 2011. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/12131.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yoo M. MEASURES OF AGREEMENT IN METHOD COMPARISON STUDIES FOR INTENSIVE LONGITUDINAL DATA
. [Thesis]. Penn State University; 2011. Available from: https://submit-etda.libraries.psu.edu/catalog/12131
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
8.
Chen, Chixiang.
Statistical Models for Recovering Dynamic Gene Networks from Static Data.
Degree: 2020, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/17909cuc472
► Because of their power to reveal temporal changes of complex systems, dynamic networks have been increasingly used in a wide range of disciplines including medical…
(more)
▼ Because of their power to reveal temporal changes of complex systems, dynamic networks
have been increasingly used in a wide range of disciplines including medical science. The
prerequisite of reconstructing such networks is the collection of temporal or perturbed
data. However, these types of data are hardly available in genomic studies of medicine,
significantly limiting the application of dynamic networks to characterize biological
principles behind human health and diseases. In this thesis, I argue that static expression
data can be converted into their dynamic representation, allowing quasi-dynamic gene
networks to be recovered from non-temporal and non-perturbed data. The basic premise
of my argument is that genes constituting a network co-vary over samples, which can be
interpreted through lens of game theory. Originated in economic research, game theory
states that each player (gene) strives to maximize its payoff (expression) based on its
own strategy and the strategy of other players until the Nash equilibrium is reached.
I integrate game theory to dissect the net expression of a gene into its underlying
independent and dependent expression components, through a system of informative,
dynamic, omnidirectional, and personalized networks (idopNetworks). The independent
expression is one that occurs when the gene is assumed to be in isolation, whereas the
dependent expression is one due to accumulative regulation by other genes. I modify
and apply derivative-free approaches to solve idopNetworks, implemented with variable
selection. I code the estimates of pairwise dependent expression of genes into a graph,
forming a bidirectional, signed, and weighted gene network that captures all network
features. Because dependent expression components dynamically vary over samples, I
convert sample-specific networks into context-specific networks to investigate how gene
co-regulation architecture evolves along with disease progression and differs among exposure
factors.
The methodologies developed in this thesis include two parts. In the first part,
I integrate the power equation of the part-whole relationship and evolutionary game
theory to derive the idopNetworks model. This model views gene networks as a closed
system in which each gene interacts with every other gene as a function of network
behavior. In the second part, I integrate the varying coefficient model and evolutionary
game theory to develop the idopNetworks model by assuming gene networks as an
open system. In this system, gene interactions change as a function of some actors
extrinsic to the system. In both parts, I demonstrate the utility and usefulness of my
models by analyzing the Genotype-Tissue Expression (GTEx) data. Although the GTEx
data have been extensively analyzed before, my data analysis obtains some previously
uncharacterized gene co-regulation mechanisms that mediate tissue specificity. I have
also derived the asymptotic property of the proposed learning procedure and evaluate its
statistical performance through extensive computer…
Advisors/Committee Members: Rongling Wu, Dissertation Advisor/Co-Advisor, Rongling Wu, Committee Chair/Co-Chair, Ming Wang, Committee Chair/Co-Chair, Vernon Michael Chinchilli, Committee Member, Joanna Floros, Outside Member, Runze Li, Committee Member, Xiang Zhan, Committee Member, Arthur Steven Berg, Program Head/Chair, Ming Wang, Dissertation Advisor/Co-Advisor.
Subjects/Keywords: The Genotype-Tissue Expression; Disease progression; Network learning; Ordinary differential equations; Quasi-dynamic network
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chen, C. (2020). Statistical Models for Recovering Dynamic Gene Networks from Static Data. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/17909cuc472
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chen, Chixiang. “Statistical Models for Recovering Dynamic Gene Networks from Static Data.” 2020. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/17909cuc472.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chen, Chixiang. “Statistical Models for Recovering Dynamic Gene Networks from Static Data.” 2020. Web. 22 Jan 2021.
Vancouver:
Chen C. Statistical Models for Recovering Dynamic Gene Networks from Static Data. [Internet] [Thesis]. Penn State University; 2020. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/17909cuc472.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chen C. Statistical Models for Recovering Dynamic Gene Networks from Static Data. [Thesis]. Penn State University; 2020. Available from: https://submit-etda.libraries.psu.edu/catalog/17909cuc472
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
9.
Wang, Haiyan.
Testing in multifactor heteroscedastic ANOVA and repeated measures
designs with large number of levels
.
Degree: 2008, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/6303
► Testing methods for factorial designs with independent or dependent observations where some of the factors have a large number of levels have received a lot…
(more)
▼ Testing methods for factorial designs with independent or dependent observations where some of the factors have a large number of levels
have received a lot of attention recently. Most results for independent data in the literature have been restricted to procedures using the
original observations for the balanced homoscedastic case, which require strong moment assumptions and are sensitive to outliers. The results in the literature for dependent data were extensively studied in parametric, nonparametric and semiparametric, and Bayesian models but all that do inference require large sample sizes or the normality assumption.
The first part of my thesis considers the use of rank statistics as robust alternatives for testing hypotheses in balanced and unbalanced, homoscedastic and heteroscedastic one-way and two-way ANOVA models when the number of levels of at least one factor is large. The second part of my thesis deals with various testing problems in
possibly unbalanced and heteroscedastic multi-factor designs with arbitrary but fixed number of factors when at least one of the factors have large number of factor levels. Procedures based on both original observations and their (mid-)ranks are presented for the same general
setting. The first two parts pertain to independent data. The third part of my thesis is focused on testing hypotheses in functional data,
a fully nonparametric method for evaluating
the effect of several crossed factors on the curve and their interactions with time.
The asymptotics, which rely on the large number of measurements per curve (subject) and not on
large group sizes, hold under the general assumption of α-mixing without specifying the covariance structure, and do not require the
measurements to be continuous or homoscedastic. A competing set of (mid-)rank procedures is also developed. The procedures in all three parts can be applied to both continuous and discrete ordinal observations. The rank tests are robust to outliers, invariant under monotone transformations, and do not require any restrictive moment conditions. Simulation studies reveal that the (mid-)rank procedures
outperform those based on the original observations in all non-normal situations while they do not lose much power when normality holds.
Applications to several data sets are given and potential extensions in several directions are discussed.
Advisors/Committee Members: Michael G Akritas, Committee Chair/Co-Chair, Rana Arnold, Committee Member, Bing Li, Committee Member, Vernon Michael Chinchilli, Committee Member.
Subjects/Keywords: repeated measurements; ANOVA; longitudinal or funcitonal data; nonparametric procedures; large dimentional data; Rank tests
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wang, H. (2008). Testing in multifactor heteroscedastic ANOVA and repeated measures
designs with large number of levels
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/6303
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Wang, Haiyan. “Testing in multifactor heteroscedastic ANOVA and repeated measures
designs with large number of levels
.” 2008. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/6303.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Wang, Haiyan. “Testing in multifactor heteroscedastic ANOVA and repeated measures
designs with large number of levels
.” 2008. Web. 22 Jan 2021.
Vancouver:
Wang H. Testing in multifactor heteroscedastic ANOVA and repeated measures
designs with large number of levels
. [Internet] [Thesis]. Penn State University; 2008. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/6303.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Wang H. Testing in multifactor heteroscedastic ANOVA and repeated measures
designs with large number of levels
. [Thesis]. Penn State University; 2008. Available from: https://submit-etda.libraries.psu.edu/catalog/6303
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
10.
Kang, Doh Yung.
CAUSAL INFERENCE BY SEMIPARAMETRIC IMPUTATION
.
Degree: 2008, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/7454
► Causal effects are comparisons among the outcomes that a study subject would have under different treatment conditions. Because no subject can receive multiple treatments at…
(more)
▼ Causal effects are comparisons among the outcomes that a study
subject would have under different treatment conditions. Because no
subject can receive multiple treatments at the same time, causal
inference may be regarded as a missing-data problem. Inferences
about causal effects are challenging in the presence of confounders,
which may distort estimated effects due to their mutual associations
with the treatment assignment and with the outcomes. To deal with
this problem, we propose a marginal causal model (MCM), a regression
that allows average causal effects to vary with respect to one or
more variables of interest. We estimate the parameters of the MCM by
constructing imputation models and replacing the missing potential
outcomes with predicted values. The causal effects are then
estimated by solving a set of estimating equations based on the
observed and imputed outcomes. To mitigate the biases that may
result when the imputation models are misspecified, we augment the
imputation models with covariates derived from estimated propensity
scores. We apply these methods to data from real and simulated
observational studies of the causal effects of dieting on body
weight among adolescent girls.
Advisors/Committee Members: Joseph Francis Schafer, Committee Chair/Co-Chair, Rana Arnold, Committee Member, Vernon Michael Chinchilli, Committee Member, Murali Haran, Committee Member.
Subjects/Keywords: estimating function; survey inference; imputation; Causal inference; missing data
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kang, D. Y. (2008). CAUSAL INFERENCE BY SEMIPARAMETRIC IMPUTATION
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/7454
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kang, Doh Yung. “CAUSAL INFERENCE BY SEMIPARAMETRIC IMPUTATION
.” 2008. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/7454.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kang, Doh Yung. “CAUSAL INFERENCE BY SEMIPARAMETRIC IMPUTATION
.” 2008. Web. 22 Jan 2021.
Vancouver:
Kang DY. CAUSAL INFERENCE BY SEMIPARAMETRIC IMPUTATION
. [Internet] [Thesis]. Penn State University; 2008. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/7454.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kang DY. CAUSAL INFERENCE BY SEMIPARAMETRIC IMPUTATION
. [Thesis]. Penn State University; 2008. Available from: https://submit-etda.libraries.psu.edu/catalog/7454
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
11.
Harris, Margaret E. Davitt.
BURDEN, UNCERTAINTY, AND PATIENT SYMPTOMATOLOGY
IN FAMILY CAREGIVERS OF HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS: A PROSPECTIVE STUDY
.
Degree: 2008, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/8856
► This descriptive study examined the experience of family caregivers of Hematopoietic Stem Cell Transplantation (HSCT) patients to identify stress-related factors that could impact the effectiveness…
(more)
▼ This descriptive study examined the experience of family caregivers of Hematopoietic Stem Cell Transplantation (HSCT) patients to identify stress-related factors that could impact the effectiveness of their caregiver role in the current atmosphere of early discharge of bone marrow transplant recipients from hospital care.
A conceptual framework that integrated caregiver burden, uncertainty, and patient symptom pattern assessment served as a basis for this prospective repeated measures study design, whereby several instruments were administered to the study participants at two sites.
Data were collected from 46 patient-caregiver dyads at four points in the acute transplant treatment process: (a) pre-transplant, (b) immediately after transplant, (3) one week after discharge from the hospital, and (d) one month after discharge. The data collection was conducted by the principal investigator at the
Penn State Milton S. Hershey Medical Center in central Pennsylvania in 2004 and by the co-investigator at the Stanford
University Hospital in Los Angeles in 2008. The data analysis was conducted using descriptive statistics, ANCOVA, and Pearson Partial Correlation.
The following were the principal findings: caregiver burden and uncertainty were most evident at Interview 1 and 2 (pre-transplant and immediately post-transplant); levels of burden and levels of uncertainty in this population were at or above levels reported for caregivers of patients with chronic diseases; burden was at a level associated with diagnosis of depression in other research; and times of highest stress were associated with the greatest difference in caregiver and patient assessment of symptoms (e.g., pain, fatigue, and other psychological and physical symptoms).
The findings of this study support the need for focused support for caregivers early in the HSCT treatment process, monitoring of caregivers for signs of clinical depression, and recognition that their stress level may alter the accuracy of their assessment of patient symptoms. The lack of increase in burden and uncertainty scores post discharge suggests that the caregivers in this study may not have found care of the patient at home to be more stressful than during hospitalization, and may have considered it to be an acceptable treatment model. Limitations related to the convenience sampling in this study support the need for additional research to confirm these findings and improve generalization to other HSCT caregiver populations. The contribution to the literature of an understanding of the family caregiver experience revealed in this study provides new insights into potential areas for the development of healthcare intervention.
Advisors/Committee Members: Carol A Smith, Committee Chair/Co-Chair, Sharon Louise Falkenstern, Committee Member, Vernon Michael Chinchilli, Committee Member, James O Ballard Iii, Committee Member, Ian M Paul, Committee Member.
Subjects/Keywords: Uncertainty; Caregivers; Burden
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Harris, M. E. D. (2008). BURDEN, UNCERTAINTY, AND PATIENT SYMPTOMATOLOGY
IN FAMILY CAREGIVERS OF HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS: A PROSPECTIVE STUDY
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/8856
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Harris, Margaret E Davitt. “BURDEN, UNCERTAINTY, AND PATIENT SYMPTOMATOLOGY
IN FAMILY CAREGIVERS OF HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS: A PROSPECTIVE STUDY
.” 2008. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/8856.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Harris, Margaret E Davitt. “BURDEN, UNCERTAINTY, AND PATIENT SYMPTOMATOLOGY
IN FAMILY CAREGIVERS OF HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS: A PROSPECTIVE STUDY
.” 2008. Web. 22 Jan 2021.
Vancouver:
Harris MED. BURDEN, UNCERTAINTY, AND PATIENT SYMPTOMATOLOGY
IN FAMILY CAREGIVERS OF HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS: A PROSPECTIVE STUDY
. [Internet] [Thesis]. Penn State University; 2008. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/8856.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Harris MED. BURDEN, UNCERTAINTY, AND PATIENT SYMPTOMATOLOGY
IN FAMILY CAREGIVERS OF HEMATOPOIETIC STEM CELL TRANSPLANT PATIENTS: A PROSPECTIVE STUDY
. [Thesis]. Penn State University; 2008. Available from: https://submit-etda.libraries.psu.edu/catalog/8856
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
12.
Hayes, Clair Nelson.
Factors affecting the magnitude of inbreeding depression in male and female function in Cucurbita pepo spp. texana (Cucurbitaceae).
Degree: 2008, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/6178
► I conducted a series of studies to investigate the nature of inbreeding depression in Cucurbita pepo ssp. texana L. (Cucurbitaceae) and identify factors that influence…
(more)
▼ I conducted a series of studies to investigate the nature of inbreeding depression in Cucurbita pepo ssp. texana L. (Cucurbitaceae) and identify factors that influence the severity of inbreeding depression. In the first study, I compared the magnitude of inbreeding depression within male and female functions at an intermediate level of inbreeding. I found that male and female functions respond independently to inbreeding, and that there was a slight tendency for inbreeding depression to be more severe for female function than for male function, implying that estimates of inbreeding depression based solely on female fitness traits might be misleading.
In the second study, I examined the relationship between coefficient of inbreeding (f) and fitness across a range of f for both male and female fitness. Fitness declined linearly with f for most traits, suggesting a simple additive among-locus genetic model for inbreeding depression in C. pepo ssp. texana and modest purging of deleterious recessives.
In the third study, I grew inbred and outcrossed plants under high and low nitrogen conditions to examine the effect of environmental stress on the magnitude of inbreeding depression. I found that differences among inbred and outcrossed individuals were more pronounced under the more stressful low nitrogen conditions. I also found evidence of fluctuating asymmetry for leaf shape among inbred plants, suggesting that inbreeding reduces developmental stability in C. pepo ssp. texana.
In the final study, I examined the relationship between inbreeding and herbivory by diabroticite beetles. Beetles preferentially attacked inbred plants and damaged a larger proportion of the leaves on inbred plants, reducing the resources available for growth and reproduction. When inbred plants were sprayed with pesticides, they had higher fitness and less severe inbreeding depression than untreated control plants, although the increase in female fitness was more pronounced than in male fitness.
I conclude that the magnitude of inbreeding depression is not a fixed property of an individual with a particular coefficient of inbreeding but rather a function of the severity of the environment in which the individual grows and matures.
Advisors/Committee Members: Andrew George Stephenson, Committee Chair/Co-Chair, James Alan Winsor, Committee Member, Hong Ma, Committee Member, Vernon Michael Chinchilli, Committee Member.
Subjects/Keywords: inbreeding; inbreeding depression; mating systems; Cucurbita; pollen; male function
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hayes, C. N. (2008). Factors affecting the magnitude of inbreeding depression in male and female function in Cucurbita pepo spp. texana (Cucurbitaceae). (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/6178
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hayes, Clair Nelson. “Factors affecting the magnitude of inbreeding depression in male and female function in Cucurbita pepo spp. texana (Cucurbitaceae).” 2008. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/6178.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hayes, Clair Nelson. “Factors affecting the magnitude of inbreeding depression in male and female function in Cucurbita pepo spp. texana (Cucurbitaceae).” 2008. Web. 22 Jan 2021.
Vancouver:
Hayes CN. Factors affecting the magnitude of inbreeding depression in male and female function in Cucurbita pepo spp. texana (Cucurbitaceae). [Internet] [Thesis]. Penn State University; 2008. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/6178.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hayes CN. Factors affecting the magnitude of inbreeding depression in male and female function in Cucurbita pepo spp. texana (Cucurbitaceae). [Thesis]. Penn State University; 2008. Available from: https://submit-etda.libraries.psu.edu/catalog/6178
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
13.
Zhang, Yiyun.
Regularization Parameter Selection for Variable Selection in High-dimensional Modelling.
Degree: 2009, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/9543
► Variable selection is an important issue in statistical modelling. Classical approaches select models by applying a penalty related to the size of the candidate model.…
(more)
▼ Variable selection is an important issue in statistical modelling. Classical approaches select models by applying a penalty related
to the size of the candidate model. Exhaustive search is required for these classical methods which is impractical in high-dimensional modelling. Adopting continuous penalties such as
the LASSO and the SCAD made it possible to cope with the high-dimensionality. Alike in classical methods, the size of regularization plays a crucial rule in their asymptotic properties. For classical methods, it is well known that AIC-like
criteria are asymptotically loss efficient in the sense that they choose the minimum loss model when the true model is infinite dimensional. On the contrary, when there is a finite dimensional
correct model, BIC-like criteria are consistent in the sense that they choose the smallest correct model with probability tending to one. Parallel properties for the penalized estimators are studied in this thesis. Extending the results of Wang, Li and Tsai (2007), we show that the consistent tuning parameter selector results in a penalized estimator that is also consistent in a general likelihood setting. On the other hand, it is shown that the tuning
parameter selector constructed from an efficient criterion is also asymptotically loss efficient for linear regression. Under the conditions imposed in this thesis, the efficiency result can also be extended to generalized linear models in terms of Kullback-Leibler loss. Our simulation studies suggest the finite sample performances are in line with the theories we present. A real data application is discussed to advocate the use of penalized likelihood variable selection procedures.
Advisors/Committee Members: Prof Runze Li, Dissertation Advisor/Co-Advisor, Runze Li, Committee Chair/Co-Chair, Bing Li, Committee Member, David Russell Hunter, Committee Member, Vernon Michael Chinchilli, Committee Member.
Subjects/Keywords: GLIM; LASSO; Penalized Likelihood; SCAD; Variable Selection
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zhang, Y. (2009). Regularization Parameter Selection for Variable Selection in High-dimensional Modelling. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/9543
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zhang, Yiyun. “Regularization Parameter Selection for Variable Selection in High-dimensional Modelling.” 2009. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/9543.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zhang, Yiyun. “Regularization Parameter Selection for Variable Selection in High-dimensional Modelling.” 2009. Web. 22 Jan 2021.
Vancouver:
Zhang Y. Regularization Parameter Selection for Variable Selection in High-dimensional Modelling. [Internet] [Thesis]. Penn State University; 2009. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/9543.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zhang Y. Regularization Parameter Selection for Variable Selection in High-dimensional Modelling. [Thesis]. Penn State University; 2009. Available from: https://submit-etda.libraries.psu.edu/catalog/9543
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
14.
Romer, Megan M.
The Statistical Analysis of Monotone Incomplete Multivariate Normal Data.
Degree: 2009, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/9755
► We consider problems in finite-sample inference with monotone incomplete data drawn from Nd(μ, Σ), a multivariate normal population with mean μ and covariance matrix Σ.…
(more)
▼ We consider problems in finite-sample inference with monotone incomplete data drawn from N
d(μ, Σ), a multivariate normal population with mean μ and covariance matrix Σ. In the case of two-step, monotone incomplete data, we show that μ-hat and Σ-hat, the maximum likelihood estimators of μ and Σ, respectively, are equivariant and obtain a new derivation of a stochastic representation for μ-hat. Our new derivation allows us to identify explicitly in terms of the data the independent random variables that arise in that stochastic representation. Again, in the case of two- step, monotone incomplete data, we derive a stochastic representation for the exact distribution of a generalization of Hotelling's T
2, and therefore obtain ellipsoidal confidence regions for μ. We then derive probability inequalities for the T
2-statistic. We apply these results to construct confidence regions for linear combinations of μ, and provide a
numerical example in which we analyze a data set consisting of cholesterol measurements
on a group of Pennsylvania hospital patients. . In the case of three-step, monotone incomplete data, we examine the independence properties and joint distribution of subvectors of μ-hat, the maximum likelihood estimator of μ. In our examination of the joint distribution of μ-hat, we first establish that μ-hat is equivariant and then identify the distribution of μ-hat up to a certain set of conditioning variables.
Advisors/Committee Members: Donald Richards, Dissertation Advisor/Co-Advisor, Rana Arnold, Committee Chair/Co-Chair, Vernon Michael Chinchilli, Committee Member, Diane Marie Henderson, Committee Member, Donald Richards, Committee Member.
Subjects/Keywords: monotone imcomplete data; multivariate normal
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Romer, M. M. (2009). The Statistical Analysis of Monotone Incomplete Multivariate Normal Data. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/9755
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Romer, Megan M. “The Statistical Analysis of Monotone Incomplete Multivariate Normal Data.” 2009. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/9755.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Romer, Megan M. “The Statistical Analysis of Monotone Incomplete Multivariate Normal Data.” 2009. Web. 22 Jan 2021.
Vancouver:
Romer MM. The Statistical Analysis of Monotone Incomplete Multivariate Normal Data. [Internet] [Thesis]. Penn State University; 2009. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/9755.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Romer MM. The Statistical Analysis of Monotone Incomplete Multivariate Normal Data. [Thesis]. Penn State University; 2009. Available from: https://submit-etda.libraries.psu.edu/catalog/9755
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
15.
Liao, Shu-Min.
HETEROSCEDASTIC UNBALANCED NESTED DESIGNS AND FULLY NONPARAMETRIC ANALYSIS OF COVARIANCE.
Degree: 2009, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/9816
► Analysis of variance is a corner stone of statistical applications. The classical asymptotic results were built either under the normality and homoscedasticity assumptions, or on…
(more)
▼ Analysis of variance is a corner stone of statistical applications. The classical asymptotic results were built either under the normality and homoscedasticity assumptions,
or on cases when the numbers of factor levels are all fixed. However, the past decade has witnessed the generation of large data sets which involve a multitude of factor levels while the number of replications per factor combination is very small. The asymptotic theory is considerably more complicated when testing against those high-dimensional alternatives.
In the first part of this thesis, we consider the problem of testing for the sub-class effect in the unbalanced two-fold nested models with a large number of sub-classes. It is shown that the classical F-statistic is very sensitive to departures from homoscedasticity, even in balanced designs. We propose new testing procedures to accommodate heteroscedasticity, and the asymptotic distributions of the proposed test statistics, both under the null and local alternative hypotheses, are established. Simulation studies examine the finite sample performance of the proposed statistics and the competing classical F-test. Two real data sets are analyzed and ramifications of these results to the hypothesis of no covariate effect in the analysis of covariance are discussed, which leads to a more sophisticated approach described in the second part of the thesis. Testing for the class effect is also investigated.
In the second part of this thesis, we introduce a new approach for testing the covariate effect in the context of the fully nonparametric ANCOVA model which capitalizes on the connection to the testing problems in nested designs. The basic idea behind the proposed method is to think of each distinct covariate value as a level of a sub-class nested in each group/class. A projection-based tool is developed to obtain a new class of quadratic forms, whose asymptotic behavior is then studied to establish the limiting distributions of the proposed test statistic under the null hypothesis and local alternatives. Simulation studies show that this new method, compared with existing alternatives, has better power properties and achieves the nominal level under violations of the classical assumptions. Three data sets are analyzed, and asymptotic results concerning testing for the covariate-adjusted group effect are also included.
Advisors/Committee Members: Michael G Akritas, Dissertation Advisor/Co-Advisor, Michael G Akritas, Committee Chair/Co-Chair, Rana Arnold, Committee Member, Francesca Chiaromonte, Committee Member, Vernon Michael Chinchilli, Committee Member.
Subjects/Keywords: nested design; ancova; fully nonparametric model; statistical testing; heteroscedasticity; asymptotic theory
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Liao, S. (2009). HETEROSCEDASTIC UNBALANCED NESTED DESIGNS AND FULLY NONPARAMETRIC ANALYSIS OF COVARIANCE. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/9816
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Liao, Shu-Min. “HETEROSCEDASTIC UNBALANCED NESTED DESIGNS AND FULLY NONPARAMETRIC ANALYSIS OF COVARIANCE.” 2009. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/9816.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Liao, Shu-Min. “HETEROSCEDASTIC UNBALANCED NESTED DESIGNS AND FULLY NONPARAMETRIC ANALYSIS OF COVARIANCE.” 2009. Web. 22 Jan 2021.
Vancouver:
Liao S. HETEROSCEDASTIC UNBALANCED NESTED DESIGNS AND FULLY NONPARAMETRIC ANALYSIS OF COVARIANCE. [Internet] [Thesis]. Penn State University; 2009. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/9816.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Liao S. HETEROSCEDASTIC UNBALANCED NESTED DESIGNS AND FULLY NONPARAMETRIC ANALYSIS OF COVARIANCE. [Thesis]. Penn State University; 2009. Available from: https://submit-etda.libraries.psu.edu/catalog/9816
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
16.
Hatfield, Linda Antoinette.
A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL EXAMINING THE ANALGESIC PROPERTIES OF
ORAL SUCROSE DURING ROUTINE IMMUNIZATIONS AT
TWO AND FOUR MONTHS OF AGE.
Degree: 2008, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/6973
► The purpose of this study is to evaluate the effectiveness of and age-related changes in analgesia of oral sucrose as a pre-procedural intervention for acute…
(more)
▼ The purpose of this study is to evaluate the effectiveness of and age-related changes in analgesia of oral sucrose as a pre-procedural intervention for acute pain during routine immunizations at two and four months of age. Melzack and Wall’s (1965) gate control theory of pain served as the theoretical frame guiding this prospective, parent and investigator- masked, randomized, clinical trial. Forty healthy term infants receiving their routine two or 4-month immunizations at
Penn State Milton S. Hershey Medical Center’s ambulatory pediatric clinic were sampled. Infants were randomized to the treatment group (24% sucrose, n=20) or the control group (sterile water, n=20). Infants’ study participation was at their two and four-month well-child visit. Treatment intervention was administered two minutes before the three serial routine immunizations. The
University of Wisconsin Children’s Hospital pain scale measured infant behavioral pain response for the treatment and control group at baseline, two, and five minutes following solution administration. A two by two repeated measures ANOVA examined the effects of treatment conditions and age on pain assessment scores.
Comparisons of change in behavioral pain response between two and four months of age were not statistically significant at two minutes and five minutes following treatment administration (p-value=1.00). Age groups were combined within treatment, to test for a difference in change in behavioral pain response between treatment and control groups at two minutes and five minutes following treatment administration. Change in pain response from baseline to two minutes following treatment administration was not statistically significant (p-value=0.958). Between the treatment and control group the change in behavioral pain response from baseline to five minutes following treatment administration was statistically significant (p<0.0001). The effect of gender (p=0.1865), nutrition (p=0.8096), prior painful experiences (p=0.2159) and analgesia (p=0.2266) on behavioral pain response were statistically non-significant.
Immunizations constitute a necessary preventive health measure in pediatric clinics. Since healthy newborns’ behavioral pain response is increased after immunizations, it is reasonable to develop practical clinical interventions to promote comfort and alleviate their pain and distress. Sucrose is an effective pre-procedure intervention for decreasing behavior pain response after immunizations at two and four months of age.
Advisors/Committee Members: Judith E Hupcey, Committee Chair/Co-Chair, Mary Beth Clark, Committee Member, Vernon Michael Chinchilli, Committee Member, Cheston Milton Berlin, Committee Member.
Subjects/Keywords: pain; pediatric pain; infant; newborn; nociception; neonatal
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hatfield, L. A. (2008). A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL EXAMINING THE ANALGESIC PROPERTIES OF
ORAL SUCROSE DURING ROUTINE IMMUNIZATIONS AT
TWO AND FOUR MONTHS OF AGE. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/6973
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hatfield, Linda Antoinette. “A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL EXAMINING THE ANALGESIC PROPERTIES OF
ORAL SUCROSE DURING ROUTINE IMMUNIZATIONS AT
TWO AND FOUR MONTHS OF AGE.” 2008. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/6973.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hatfield, Linda Antoinette. “A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL EXAMINING THE ANALGESIC PROPERTIES OF
ORAL SUCROSE DURING ROUTINE IMMUNIZATIONS AT
TWO AND FOUR MONTHS OF AGE.” 2008. Web. 22 Jan 2021.
Vancouver:
Hatfield LA. A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL EXAMINING THE ANALGESIC PROPERTIES OF
ORAL SUCROSE DURING ROUTINE IMMUNIZATIONS AT
TWO AND FOUR MONTHS OF AGE. [Internet] [Thesis]. Penn State University; 2008. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/6973.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hatfield LA. A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED TRIAL EXAMINING THE ANALGESIC PROPERTIES OF
ORAL SUCROSE DURING ROUTINE IMMUNIZATIONS AT
TWO AND FOUR MONTHS OF AGE. [Thesis]. Penn State University; 2008. Available from: https://submit-etda.libraries.psu.edu/catalog/6973
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
17.
Xu, Hong.
Contributions to Adatpive Web Sampling Designs
.
Degree: 2008, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/7542
► Investigation of the characteristics and estimation of quantities of hidden and hard-to-access population are of interest to scientists. Such populations are difficult to target because…
(more)
▼ Investigation of the characteristics and estimation of quantities of hidden and hard-to-access population are of interest to scientists. Such populations are difficult to target because of their elusive nature or other prohibitive characteristics. So crafting designs of a representative sample and creating estimation methods to obtain efficient information from the sampled data are core challenges for people who investigate
sampling theories and applications. Thompson (2006a) proposed an adaptive web sampling ( AWS ) scheme which takes into account the social networks between subjects to get a more efficient sample, and the procedures are more flexible than adaptive sampling. Three papers which contribute to AWS are included in this thesis. They focus on new resampling mythologies to improve the inferential estimation, produce designs with practical restrictions to minimize the cost and maximize the sampling simultaneously and
model based estimation for non-responses. Simulated and real data sets are used to demonstrate implementation.
Advisors/Committee Members: James Landis Rosenberger, Committee Chair/Co-Chair, Steve K Thompson, Committee Chair/Co-Chair, Vernon Michael Chinchilli, Committee Member, Runze Li, Committee Member, Mosuk Chow, Committee Member.
Subjects/Keywords: cost; adaptive sampling; sampling; adaptive web sampling; resampling; nonresponses
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Xu, H. (2008). Contributions to Adatpive Web Sampling Designs
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/7542
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Xu, Hong. “Contributions to Adatpive Web Sampling Designs
.” 2008. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/7542.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Xu, Hong. “Contributions to Adatpive Web Sampling Designs
.” 2008. Web. 22 Jan 2021.
Vancouver:
Xu H. Contributions to Adatpive Web Sampling Designs
. [Internet] [Thesis]. Penn State University; 2008. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/7542.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Xu H. Contributions to Adatpive Web Sampling Designs
. [Thesis]. Penn State University; 2008. Available from: https://submit-etda.libraries.psu.edu/catalog/7542
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
18.
Soprano, Cherie Ann.
EFFECTS OF ANIMAL-ASSISTED THERAPY FOR RESPONDING TO PASSIVE BEHAVIOR IN ELDERLY NURSING HOME RESIDENTS WITH DEMENTIA: A SINGLE-SUBJECT DESIGN STUDY
.
Degree: 2010, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/10526
► Passive behavior (PB) is a behavioral disturbance that affects 61 to 88 percent of nursing home residents (NHRs) with dementia. PB in persons with dementia…
(more)
▼ Passive behavior (PB) is a behavioral disturbance that affects 61 to 88 percent of nursing home residents (NHRs) with dementia. PB in persons with dementia (PWD) often leads to such negative consequences as, social isolation, loss of physical functioning, excess disability, and further cognitive decline, which, in turn, may lead to loss of quality of life, increased morbidity and mortality, and caregiver distress. PB in PWD is often misdiagnosed as depression and treated with psychoactive medications. The black-box warning against the use of psychoactive medications in PWD warrant the need for non-pharmacological interventions aimed at better managing PB in PWD. Many studies have suggested health and social benefits may be derived from animal-assisted therapy (AAT). The specific aim of the present study was to determine if a functional relationship existed between AAT and PB in PWD. The Need-driven Dementia-compromised Behavior Model (NDB) and attachment theory (AT) were the organizing frameworks for this study. A within-subject, repeated measurements, quasi-experimental
A-B1-A´-B2 design was used to measure PB. Eight subjects, who met the study’s inclusion criteria, completed 32, daily, 20-minute sessions under two conditions: dog present and dog absent. Sessions were videotaped and measures of PB were obtained from the video-recordings, using the Observational Form of Passivity in Dementia (O-PDS) scale. Pairwise t tests were performed on the adjusted mean scores of the O-PDS. Visual analyses of the graphs of O-PDS scores consistently demonstrated significantly less PB in 7 of the 8 subjects during the AAT conditions. Findings suggest that AAT can serve as a useful intervention for decreasing PB in PWD.
Advisors/Committee Members: Ann Marie Kolanowski, Dissertation Advisor/Co-Advisor, Ann Marie Kolanowski, Committee Chair/Co-Chair, Vernon Michael Chinchilli, Committee Member, Janice Lee Penrod, Committee Member, Daniel Jay Lago, Committee Member, Dr Kathleen Colling, Committee Member.
Subjects/Keywords: passive behavior; Alzheimer’s disease; animal assisted therapy; dementia
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Soprano, C. A. (2010). EFFECTS OF ANIMAL-ASSISTED THERAPY FOR RESPONDING TO PASSIVE BEHAVIOR IN ELDERLY NURSING HOME RESIDENTS WITH DEMENTIA: A SINGLE-SUBJECT DESIGN STUDY
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/10526
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Soprano, Cherie Ann. “EFFECTS OF ANIMAL-ASSISTED THERAPY FOR RESPONDING TO PASSIVE BEHAVIOR IN ELDERLY NURSING HOME RESIDENTS WITH DEMENTIA: A SINGLE-SUBJECT DESIGN STUDY
.” 2010. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/10526.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Soprano, Cherie Ann. “EFFECTS OF ANIMAL-ASSISTED THERAPY FOR RESPONDING TO PASSIVE BEHAVIOR IN ELDERLY NURSING HOME RESIDENTS WITH DEMENTIA: A SINGLE-SUBJECT DESIGN STUDY
.” 2010. Web. 22 Jan 2021.
Vancouver:
Soprano CA. EFFECTS OF ANIMAL-ASSISTED THERAPY FOR RESPONDING TO PASSIVE BEHAVIOR IN ELDERLY NURSING HOME RESIDENTS WITH DEMENTIA: A SINGLE-SUBJECT DESIGN STUDY
. [Internet] [Thesis]. Penn State University; 2010. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/10526.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Soprano CA. EFFECTS OF ANIMAL-ASSISTED THERAPY FOR RESPONDING TO PASSIVE BEHAVIOR IN ELDERLY NURSING HOME RESIDENTS WITH DEMENTIA: A SINGLE-SUBJECT DESIGN STUDY
. [Thesis]. Penn State University; 2010. Available from: https://submit-etda.libraries.psu.edu/catalog/10526
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
19.
Reck, Donna Hart.
Patients' Expectations and Satisfaction with Nursing Care, and Their Nurses' Awareness of Their Expectations
.
Degree: 2010, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/11079
► This study of patient satisfaction with nursing care operationalized patients’ expectations for their nursing care as the care they anticipated receiving during their present hospitalization…
(more)
▼ This study of patient satisfaction with nursing care operationalized patients’ expectations for their nursing care as the care they anticipated receiving during their present hospitalization from their actual nurses, rather than as the level of care they imagined they would receive in the ideal hospital setting, which was how patients’ expectations have been operationalized in past studies. This study also examined whether nurses’ assessments of their patients’ expectations correlated with the patients’ reports of their expectations. A descriptive correlational mixed-method research design was used to examine the relationships between two predictor variables (patients’ expectations before hospitalization, and nurses’ assessments of patients’ expectations of care) and the outcome variable (patient satisfaction with nursing care). The existing Patient Satisfaction with Nursing Care Quality Questionnaire was modified to create a questionnaire to measure patients’ expectations with nursing care (Patient Expectations for Nursing Care Quality Questionnaire) and one to measure nurses’ assessments of their patients’ expectations (Nurse’s Assessment of the Patient’s Expectations Questionnaire). The qualitative portion of this study was based on data obtained from a subgroup of the initial patients’ responses to four open-ended questions regarding their nursing-care experience. The convenience sample for the study consisted of 109 patient-nurse dyads at an academic medical center. The target patient population consisted of patients hospitalized with an anticipated length of stay of two or more days. In each dyad, the nurse was the nurse who cared for the patient. The study found no relationship between nurses’ assessments of patients’ expectations and patients’ ratings of their own expectations, or between nurses’ assessments of patients’ expectations and patients’ satisfaction. There was, however, a moderate relationship between patients’ expectations and satisfaction, and the meaning of the relationship was considered. The qualitative comments were consistent with the quantitative results and both types of data support the same conclusion about the patients’ experiences. A significant outcome of this study was the development of a measure that allows patients to rate their expectations for nursing care and another measure that allowed nurses to give their assessment of patients’ expectations.
Advisors/Committee Members: Dr Paula Milone Nuzzo, Dissertation Advisor/Co-Advisor, Paula F Milone Nuzzo, Committee Chair/Co-Chair, Judith E Hupcey, Committee Member, Vernon Michael Chinchilli, Committee Member, James Truman Ziegenfuss Jr., Committee Member.
Subjects/Keywords: patient satisfaction with nursing care; descriptive correlational mixed-method design; nurrse-patient relationship; patients’ expectations; nurses’ assessments of patients’ expectations
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Reck, D. H. (2010). Patients' Expectations and Satisfaction with Nursing Care, and Their Nurses' Awareness of Their Expectations
. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/11079
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Reck, Donna Hart. “Patients' Expectations and Satisfaction with Nursing Care, and Their Nurses' Awareness of Their Expectations
.” 2010. Thesis, Penn State University. Accessed January 22, 2021.
https://submit-etda.libraries.psu.edu/catalog/11079.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Reck, Donna Hart. “Patients' Expectations and Satisfaction with Nursing Care, and Their Nurses' Awareness of Their Expectations
.” 2010. Web. 22 Jan 2021.
Vancouver:
Reck DH. Patients' Expectations and Satisfaction with Nursing Care, and Their Nurses' Awareness of Their Expectations
. [Internet] [Thesis]. Penn State University; 2010. [cited 2021 Jan 22].
Available from: https://submit-etda.libraries.psu.edu/catalog/11079.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Reck DH. Patients' Expectations and Satisfaction with Nursing Care, and Their Nurses' Awareness of Their Expectations
. [Thesis]. Penn State University; 2010. Available from: https://submit-etda.libraries.psu.edu/catalog/11079
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
.