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1. Kremers, Romy. Thrombin dynamics.

Degree: 2016, NARCIS

Cardiovascular diseases (CVDs) are the number one cause of death globally. In 2012, 17.5 million people died of CVDs, of which 43% were caused by ischemic heart disease and 38% by stroke. Thrombosis plays a pivotal role in the development of ischemic heart disease and stroke. Therefore, the haemostatic system has been one of the main targets of prevent and clinical management of thrombosis related pathologies. Adequate diagnosis of a medical condition is pivotal in the fight against thrombosis and the development of a suitable diagnostic test that can accurately predict the thrombotic risk is essential in the development of an effective treatment strategy to treat thrombosis. In this thesis the thrombin dynamics method was introduced, a technique to investigate both the pro- and anticoagulant processes that underlie thrombin generation separately. This method was used to study how these two processes deviates in different patient groups such as patients with liver cirrhosis and patients who are being treated with anticoagulants. Advisors/Committee Members: ten Cate, Hugo, Hemker, Hendric, Wagenvoord, Robert, de Laat, Bas, RS: CARIM - R1.01 - Blood proteins & engineering, Promovendi CD, Biochemie.

Subjects/Keywords: cardiovascular diseases; coagulation; diagnosis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Kremers, R. (2016). Thrombin dynamics. (Doctoral Dissertation). NARCIS. Retrieved from https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; 20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe

Chicago Manual of Style (16th Edition):

Kremers, Romy. “Thrombin dynamics.” 2016. Doctoral Dissertation, NARCIS. Accessed October 29, 2020. https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; 20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe.

MLA Handbook (7th Edition):

Kremers, Romy. “Thrombin dynamics.” 2016. Web. 29 Oct 2020.

Vancouver:

Kremers R. Thrombin dynamics. [Internet] [Doctoral dissertation]. NARCIS; 2016. [cited 2020 Oct 29]. Available from: https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; 20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe.

Council of Science Editors:

Kremers R. Thrombin dynamics. [Doctoral Dissertation]. NARCIS; 2016. Available from: https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; 20180bb8-3336-45ce-aeff-309ab08fe1fe ; urn:nbn:nl:ui:27-20180bb8-3336-45ce-aeff-309ab08fe1fe ; https://cris.maastrichtuniversity.nl/en/publications/20180bb8-3336-45ce-aeff-309ab08fe1fe

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