Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

You searched for +publisher:"NARCIS" +contributor:("de Laat, B."). Showing records 1 – 3 of 3 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters

1. Dragt, B.S. Unraveling von Willebrand factor extracellular traps.

Degree: Faculteit der Geneeskunde, 2013, NARCIS

Endothelial cells (ECs) provide a barrier between blood and the underlying tissue. Upon stimulation, specific storage organelles, designated Weibel-Palade bodies (WPBs), fuse with the plasmamembrane and release various components into the bloodstream. The main component of WPBs is von Willebrand factor (VWF), a multimeric glycoprotein which upon its release by endothelial cells is converted into ultra large VWF strings that capture blood platelets. In this thesis we aim to further unravel the biogenesis and functional significance of VWF strings. Advisors/Committee Members: Voorberg, J.J., de Laat, B..

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Dragt, B. S. (2013). Unraveling von Willebrand factor extracellular traps. (Doctoral Dissertation). NARCIS. Retrieved from https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html ; urn:nbn:nl:ui:29-460885 ; 2d623ff7-efad-420a-897b-b05b7510d6bd ; 11245/1.400877 ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-460885 ; https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html

Chicago Manual of Style (16th Edition):

Dragt, B S. “Unraveling von Willebrand factor extracellular traps.” 2013. Doctoral Dissertation, NARCIS. Accessed October 29, 2020. https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html ; urn:nbn:nl:ui:29-460885 ; 2d623ff7-efad-420a-897b-b05b7510d6bd ; 11245/1.400877 ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-460885 ; https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html.

MLA Handbook (7th Edition):

Dragt, B S. “Unraveling von Willebrand factor extracellular traps.” 2013. Web. 29 Oct 2020.

Vancouver:

Dragt BS. Unraveling von Willebrand factor extracellular traps. [Internet] [Doctoral dissertation]. NARCIS; 2013. [cited 2020 Oct 29]. Available from: https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html ; urn:nbn:nl:ui:29-460885 ; 2d623ff7-efad-420a-897b-b05b7510d6bd ; 11245/1.400877 ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-460885 ; https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html.

Council of Science Editors:

Dragt BS. Unraveling von Willebrand factor extracellular traps. [Doctoral Dissertation]. NARCIS; 2013. Available from: https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html ; urn:nbn:nl:ui:29-460885 ; 2d623ff7-efad-420a-897b-b05b7510d6bd ; 11245/1.400877 ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-460885 ; https://dare.uva.nl/personal/pure/en/publications/unraveling-von-willebrand-factor-extracellular-traps(2d623ff7-efad-420a-897b-b05b7510d6bd).html

2. Dragt, Bieuwke S. Unraveling von Willebrand factor extracellular traps.

Degree: 2013, NARCIS

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Dragt, B. S. (2013). Unraveling von Willebrand factor extracellular traps. (Doctoral Dissertation). NARCIS. Retrieved from https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; 6e39b884-92c4-41ea-a980-279482613a6f ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html

Chicago Manual of Style (16th Edition):

Dragt, Bieuwke S. “Unraveling von Willebrand factor extracellular traps.” 2013. Doctoral Dissertation, NARCIS. Accessed October 29, 2020. https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; 6e39b884-92c4-41ea-a980-279482613a6f ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html.

MLA Handbook (7th Edition):

Dragt, Bieuwke S. “Unraveling von Willebrand factor extracellular traps.” 2013. Web. 29 Oct 2020.

Vancouver:

Dragt BS. Unraveling von Willebrand factor extracellular traps. [Internet] [Doctoral dissertation]. NARCIS; 2013. [cited 2020 Oct 29]. Available from: https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; 6e39b884-92c4-41ea-a980-279482613a6f ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html.

Council of Science Editors:

Dragt BS. Unraveling von Willebrand factor extracellular traps. [Doctoral Dissertation]. NARCIS; 2013. Available from: https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; 6e39b884-92c4-41ea-a980-279482613a6f ; urn:isbn:9789461823670 ; urn:nbn:nl:ui:29-6e39b884-92c4-41ea-a980-279482613a6f ; https://pure.amc.nl/en/publications/unraveling-von-willebrand-factor-extracellular-traps(6e39b884-92c4-41ea-a980-279482613a6f).html

3. van Geffen, Ankie. Complex platelet phenotyping: integrative assessment of platelet activity in haemostasis and thrombosis.

Degree: 2018, NARCIS

For my dissertation, I researched the complex mechanisms underlying thrombosis. Using the flow chamber model (a perfusion model that simulates thrombosis formation in a blood vessel), I measured thrombus formation in flowing blood by examining various vessel wall components and markers for platelet activation and blood clotting over time (kinetics). In healthy people, individual differences in the parameters for thrombus formation were discovered that could be partially explained by variations in and among genes. By measuring the kinetics of thrombus and fibrin formation, a new stimulation mechanism of the intrinsic coagulation pathway through tissue factor was discovered. In the blood of mice with hyperlipidaemia, thrombus formation was significantly higher, caused in particular by elevated platelet cholesterol. Advisors/Committee Members: Heemskerk, Johan, M.E.J., Kuipers, de Laat, B., Biochemie, RS: CARIM - R1 - Thrombosis and haemostasis.

Subjects/Keywords: flow chamber; platelets; coagulation; thrombus formation; kinetics

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

van Geffen, A. (2018). Complex platelet phenotyping: integrative assessment of platelet activity in haemostasis and thrombosis. (Doctoral Dissertation). NARCIS. Retrieved from https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; 5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2

Chicago Manual of Style (16th Edition):

van Geffen, Ankie. “Complex platelet phenotyping: integrative assessment of platelet activity in haemostasis and thrombosis.” 2018. Doctoral Dissertation, NARCIS. Accessed October 29, 2020. https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; 5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2.

MLA Handbook (7th Edition):

van Geffen, Ankie. “Complex platelet phenotyping: integrative assessment of platelet activity in haemostasis and thrombosis.” 2018. Web. 29 Oct 2020.

Vancouver:

van Geffen A. Complex platelet phenotyping: integrative assessment of platelet activity in haemostasis and thrombosis. [Internet] [Doctoral dissertation]. NARCIS; 2018. [cited 2020 Oct 29]. Available from: https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; 5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2.

Council of Science Editors:

van Geffen A. Complex platelet phenotyping: integrative assessment of platelet activity in haemostasis and thrombosis. [Doctoral Dissertation]. NARCIS; 2018. Available from: https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; 5072d274-5807-48b4-b7cc-30b8aa2889c2 ; urn:nbn:nl:ui:27-5072d274-5807-48b4-b7cc-30b8aa2889c2 ; https://cris.maastrichtuniversity.nl/en/publications/5072d274-5807-48b4-b7cc-30b8aa2889c2

.