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You searched for +publisher:"Maastricht University" +contributor:("Cosemans, Judith"). Showing records 1 – 3 of 3 total matches.

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1. Gilio, K. All roads lead to thrombus formation : demystifying platelet signaling pathways.

Degree: 2012, Maastricht University

Blood platelets have a central role in the process of haemostasis (the process of making the bleeding stop in a damaged blood vessel wall) and thrombosis (clotting of a blood vessel). The latter can lead to blood vessel obstruction causing a heart infarct or a stroke. The current antithrombotic, anti-blood vessel medication is only partly effective, and an increased risk of bleeding often creates a considerable complication. For the development of personalized target-specific medication with fewer side-effects a more exact knowledge of the complex process of thrombus formation and mainly the involved blood vessel signalling pathways is essential. The insight described in this thesis is a contribution to future developments in the treatment of arterial thrombosis. Advisors/Committee Members: Heemskerk, Johan, Cosemans, Judith, Promovendi CD.

Subjects/Keywords: Blood platelets; thrombus formation; signalling pathways

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Gilio, K. (2012). All roads lead to thrombus formation : demystifying platelet signaling pathways. (Doctoral Dissertation). Maastricht University. Retrieved from https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; 9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:isbn:9789090271507 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529

Chicago Manual of Style (16th Edition):

Gilio, K. “All roads lead to thrombus formation : demystifying platelet signaling pathways.” 2012. Doctoral Dissertation, Maastricht University. Accessed November 28, 2020. https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; 9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:isbn:9789090271507 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529.

MLA Handbook (7th Edition):

Gilio, K. “All roads lead to thrombus formation : demystifying platelet signaling pathways.” 2012. Web. 28 Nov 2020.

Vancouver:

Gilio K. All roads lead to thrombus formation : demystifying platelet signaling pathways. [Internet] [Doctoral dissertation]. Maastricht University; 2012. [cited 2020 Nov 28]. Available from: https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; 9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:isbn:9789090271507 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529.

Council of Science Editors:

Gilio K. All roads lead to thrombus formation : demystifying platelet signaling pathways. [Doctoral Dissertation]. Maastricht University; 2012. Available from: https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; 9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; urn:isbn:9789090271507 ; urn:nbn:nl:ui:27-9383b1ab-f3a3-4b51-8094-f0fd0efe7529 ; https://cris.maastrichtuniversity.nl/en/publications/9383b1ab-f3a3-4b51-8094-f0fd0efe7529

2. Unal - Nergiz, R. Platelets in atherothrombosis : roles of CD36 and P2Y12 receptors.

Degree: 2011, Maastricht University

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Unal - Nergiz, R. (2011). Platelets in atherothrombosis : roles of CD36 and P2Y12 receptors. (Doctoral Dissertation). Maastricht University. Retrieved from https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; f040aa77-1c07-4d27-922f-9a925831c09b ; urn:isbn:9789081732000 ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b

Chicago Manual of Style (16th Edition):

Unal - Nergiz, R. “Platelets in atherothrombosis : roles of CD36 and P2Y12 receptors.” 2011. Doctoral Dissertation, Maastricht University. Accessed November 28, 2020. https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; f040aa77-1c07-4d27-922f-9a925831c09b ; urn:isbn:9789081732000 ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b.

MLA Handbook (7th Edition):

Unal - Nergiz, R. “Platelets in atherothrombosis : roles of CD36 and P2Y12 receptors.” 2011. Web. 28 Nov 2020.

Vancouver:

Unal - Nergiz R. Platelets in atherothrombosis : roles of CD36 and P2Y12 receptors. [Internet] [Doctoral dissertation]. Maastricht University; 2011. [cited 2020 Nov 28]. Available from: https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; f040aa77-1c07-4d27-922f-9a925831c09b ; urn:isbn:9789081732000 ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b.

Council of Science Editors:

Unal - Nergiz R. Platelets in atherothrombosis : roles of CD36 and P2Y12 receptors. [Doctoral Dissertation]. Maastricht University; 2011. Available from: https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; f040aa77-1c07-4d27-922f-9a925831c09b ; urn:isbn:9789081732000 ; urn:nbn:nl:ui:27-f040aa77-1c07-4d27-922f-9a925831c09b ; https://cris.maastrichtuniversity.nl/en/publications/f040aa77-1c07-4d27-922f-9a925831c09b

3. Mattheij, N. J. A. Molecular mechanisms underlying the platelet procoagulant response: back to basics.

Degree: 2016, Maastricht University

Differently sized platelets are present during activated coagulation, such as aggregated cells, activated clotting platelets and platelet-fibrinogen interactions. The stability of a blood clot is determined by the generation of a coagulation-active surface and the inactivation of integrin receptors. Platelets increase their surface area through balloon formation to improve the binding capacity of coagulation factors. Patients with Scott syndrome, a rare congenital bleeding disorder, and a defect in the protein anoctamine-6 have platelets with significantly reduced blood coagulation. Using in-vitro and ex-vivo experiments and genetically modified mice, we found a direct link between the presence of anoctamine-6 and the development of coagulation-active platelets and haemorrhage. The absence of anoctamine-6 results in several changes to the protein levels of Scott platelets, which may explain this complex phenotype. Advisors/Committee Members: Heemskerk, Johan, Cosemans, Judith, RS: CARIM - R1 - Thrombosis and haemostasis, Promovendi CD, Biochemie.

Subjects/Keywords: platelets; coagulation; Scott syndrome

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Mattheij, N. J. A. (2016). Molecular mechanisms underlying the platelet procoagulant response: back to basics. (Doctoral Dissertation). Maastricht University. Retrieved from https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; 0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:isbn:9789064649615 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7

Chicago Manual of Style (16th Edition):

Mattheij, N J A. “Molecular mechanisms underlying the platelet procoagulant response: back to basics.” 2016. Doctoral Dissertation, Maastricht University. Accessed November 28, 2020. https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; 0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:isbn:9789064649615 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7.

MLA Handbook (7th Edition):

Mattheij, N J A. “Molecular mechanisms underlying the platelet procoagulant response: back to basics.” 2016. Web. 28 Nov 2020.

Vancouver:

Mattheij NJA. Molecular mechanisms underlying the platelet procoagulant response: back to basics. [Internet] [Doctoral dissertation]. Maastricht University; 2016. [cited 2020 Nov 28]. Available from: https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; 0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:isbn:9789064649615 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7.

Council of Science Editors:

Mattheij NJA. Molecular mechanisms underlying the platelet procoagulant response: back to basics. [Doctoral Dissertation]. Maastricht University; 2016. Available from: https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; 0a74128b-afbf-4723-803b-8306d3465ec7 ; urn:isbn:9789064649615 ; urn:nbn:nl:ui:27-0a74128b-afbf-4723-803b-8306d3465ec7 ; https://cris.maastrichtuniversity.nl/en/publications/0a74128b-afbf-4723-803b-8306d3465ec7

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