+publisher:"Ghent University" +contributor:("Nelis, Hans")

1. Vandenbosch, Davy. Miconazole resistance in fungal biofilms : a molecular point of view.

Degree: 2013, Ghent University

URL: http://hdl.handle.net/1854/LU-3259934

► The interest in fungal biofilm formation and in the resistance of fungal biofilms against antimicrobial agents has increased due to the expanding problem of biofilm-related… (more)

Subjects/Keywords: Biology and Life Sciences

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APA (6^th Edition):

Vandenbosch, D. (2013). Miconazole resistance in fungal biofilms : a molecular point of view. (Thesis). Ghent University. Retrieved from http://hdl.handle.net/1854/LU-3259934

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vandenbosch, Davy. “Miconazole resistance in fungal biofilms : a molecular point of view.” 2013. Thesis, Ghent University. Accessed January 21, 2021. http://hdl.handle.net/1854/LU-3259934.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vandenbosch, Davy. “Miconazole resistance in fungal biofilms : a molecular point of view.” 2013. Web. 21 Jan 2021.

Vancouver:

Vandenbosch D. Miconazole resistance in fungal biofilms : a molecular point of view. [Internet] [Thesis]. Ghent University; 2013. [cited 2021 Jan 21]. Available from: http://hdl.handle.net/1854/LU-3259934.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vandenbosch D. Miconazole resistance in fungal biofilms : a molecular point of view. [Thesis]. Ghent University; 2013. Available from: http://hdl.handle.net/1854/LU-3259934

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Van Acker, Heleen. Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms.

Degree: 2014, Ghent University

URL: http://hdl.handle.net/1854/LU-4412032

► Burkholderia cenocepacia J2315 is a member of the Burkholderia cepacia complex (Bcc), a group of 18 closely related metabolically versatile microorganisms. These opportunistic pathogens can… (more)

▼ Burkholderia cenocepacia J2315 is a member of the Burkholderia cepacia complex (Bcc), a group of 18 closely related metabolically versatile microorganisms. These opportunistic pathogens can cause severe lung infections in cystic fibrosis patients. Infections are often difficult to treat due to innate resistance of Bcc species to antimicrobials and because of their capacity to form biofilms. One of the mechanisms thought to be involved in biofilm resilience is the presence of persister cells. The main aim of this dissertation was to investigate whether persister cells are present in B. cenocepacia biofilms, what the molecular basis of antimicrobial tolerance is, and how persisters can be eradicated. We confirmed the presence of persister cells in B. cenocepacia biofilms and found that genes encoding proteins involved in ROS production are downregulated in persister cells, whereas the glyoxylate shunt is upregulated. Additionally, we found that toxin antitoxin (TA)-modules are involved in persistence. Searching for TA-modules we also identified an interesting operon (BCAM0257-8) located in the B. cepacia epidemic strain marker region. This module plays a role in persistence and in addition, BCAM0258 functions as a regulator influencing quorum sensing and activating cellular pathways involved in iron acquisition and biofilm formation. Overexpression of BCAM0257 was found to increase virulence in Galleria mellonella. Genes similar to BCAM0257-8 are found in all sequenced B. cenocepacia ET-12 genomes and its presence may help explaining why infections with strains of the B. cenocepacia ET-12 lineage are so difficult to treat. Furthermore, we evaluated in vitro the bacteriostatic and bactericidal activity of temocillin, a 6-α-methoxy-penicillin against planktonic and sessile Bcc bacteria. Our data indicate that, although temocillin has a good bacteriostatic activity against planktonic cultures and 4-h old biofilms, it is of limited use to eradicate mature biofilms. Advisors/Committee Members: Coenye, Tom, Nelis, Hans.

Subjects/Keywords: Biology and Life Sciences; persistence; Burkholderia; ROS; toxin antitoxin modules; biofilm

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Van Acker, H. (2014). Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms. (Thesis). Ghent University. Retrieved from http://hdl.handle.net/1854/LU-4412032

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Van Acker, Heleen. “Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms.” 2014. Thesis, Ghent University. Accessed January 21, 2021. http://hdl.handle.net/1854/LU-4412032.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Van Acker, Heleen. “Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms.” 2014. Web. 21 Jan 2021.

Vancouver:

Van Acker H. Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms. [Internet] [Thesis]. Ghent University; 2014. [cited 2021 Jan 21]. Available from: http://hdl.handle.net/1854/LU-4412032.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Van Acker H. Molecular mechanisms of persistence in Burkholderia cenocepacia biofilms. [Thesis]. Ghent University; 2014. Available from: http://hdl.handle.net/1854/LU-4412032

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Christiaen, Steven. Exploring the role of quorum sensing and quorum sensing inhibition in the biotherapeutic potential of bacteria.

Degree: 2014, Ghent University

URL: http://hdl.handle.net/1854/LU-4232258

► The involvement of quorum sensing (QS) in several pathogenic bacteria to control biofilm formation and the expression of their virulence factors makes interfering with QS… (more)

Subjects/Keywords: Medicine and Health Sciences; quorum sensing; biotherapeutics; quorum quenching; probiotics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Christiaen, S. (2014). Exploring the role of quorum sensing and quorum sensing inhibition in the biotherapeutic potential of bacteria. (Thesis). Ghent University. Retrieved from http://hdl.handle.net/1854/LU-4232258

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Christiaen, Steven. “Exploring the role of quorum sensing and quorum sensing inhibition in the biotherapeutic potential of bacteria.” 2014. Thesis, Ghent University. Accessed January 21, 2021. http://hdl.handle.net/1854/LU-4232258.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Christiaen, Steven. “Exploring the role of quorum sensing and quorum sensing inhibition in the biotherapeutic potential of bacteria.” 2014. Web. 21 Jan 2021.

Vancouver:

Christiaen S. Exploring the role of quorum sensing and quorum sensing inhibition in the biotherapeutic potential of bacteria. [Internet] [Thesis]. Ghent University; 2014. [cited 2021 Jan 21]. Available from: http://hdl.handle.net/1854/LU-4232258.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Christiaen S. Exploring the role of quorum sensing and quorum sensing inhibition in the biotherapeutic potential of bacteria. [Thesis]. Ghent University; 2014. Available from: http://hdl.handle.net/1854/LU-4232258

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

4. De Vos, Muriel. Evaluatie van vaste fase cytometrie voor de detectie en de leefbaarheidsbepaling van fungi.

Degree: 2005, Ghent University

URL: http://hdl.handle.net/1854/LU-468490

Subjects/Keywords: Biology and Life Sciences

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

De Vos, M. (2005). Evaluatie van vaste fase cytometrie voor de detectie en de leefbaarheidsbepaling van fungi. (Thesis). Ghent University. Retrieved from http://hdl.handle.net/1854/LU-468490

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

De Vos, Muriel. “Evaluatie van vaste fase cytometrie voor de detectie en de leefbaarheidsbepaling van fungi.” 2005. Thesis, Ghent University. Accessed January 21, 2021. http://hdl.handle.net/1854/LU-468490.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

De Vos, Muriel. “Evaluatie van vaste fase cytometrie voor de detectie en de leefbaarheidsbepaling van fungi.” 2005. Web. 21 Jan 2021.

Vancouver:

De Vos M. Evaluatie van vaste fase cytometrie voor de detectie en de leefbaarheidsbepaling van fungi. [Internet] [Thesis]. Ghent University; 2005. [cited 2021 Jan 21]. Available from: http://hdl.handle.net/1854/LU-468490.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

De Vos M. Evaluatie van vaste fase cytometrie voor de detectie en de leefbaarheidsbepaling van fungi. [Thesis]. Ghent University; 2005. Available from: http://hdl.handle.net/1854/LU-468490

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Messiaen, Anne-Sophie. Towards improvement of antibiotic therapy for treating Burkholderia cepacia complex biofilm infections in cystic fibrosis patients.

Degree: 2013, Ghent University

URL: http://hdl.handle.net/1854/LU-4158756

Subjects/Keywords: Medicine and Health Sciences

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Messiaen, A. (2013). Towards improvement of antibiotic therapy for treating Burkholderia cepacia complex biofilm infections in cystic fibrosis patients. (Thesis). Ghent University. Retrieved from http://hdl.handle.net/1854/LU-4158756

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Messiaen, Anne-Sophie. “Towards improvement of antibiotic therapy for treating Burkholderia cepacia complex biofilm infections in cystic fibrosis patients.” 2013. Thesis, Ghent University. Accessed January 21, 2021. http://hdl.handle.net/1854/LU-4158756.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Messiaen, Anne-Sophie. “Towards improvement of antibiotic therapy for treating Burkholderia cepacia complex biofilm infections in cystic fibrosis patients.” 2013. Web. 21 Jan 2021.

Vancouver:

Messiaen A. Towards improvement of antibiotic therapy for treating Burkholderia cepacia complex biofilm infections in cystic fibrosis patients. [Internet] [Thesis]. Ghent University; 2013. [cited 2021 Jan 21]. Available from: http://hdl.handle.net/1854/LU-4158756.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Messiaen A. Towards improvement of antibiotic therapy for treating Burkholderia cepacia complex biofilm infections in cystic fibrosis patients. [Thesis]. Ghent University; 2013. Available from: http://hdl.handle.net/1854/LU-4158756

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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