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You searched for +publisher:"Georgia Tech" +contributor:("Sullivan, Matthew"). One record found.

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Georgia Tech

1. Taylor, Bradford. Population dynamics of multiple viral infections.

Degree: PhD, Physics, 2016, Georgia Tech

Interactions between viruses can occur when infecting the same host cell. These interactions can alter dynamical parameters of infection ultimately affecting the ecological and evolutionary dynamics of viruses and their hosts. In this thesis, I address through theory and experiment the causes and effects of multiple viral infections at the scale of the population. First, through individual-based models, I show that spatial clustering of host and viral populations emerge dynamically by varying key viral parameters related to the dispersal of progeny phage. Associated with the population clustering are increased numbers of hosts with multiple infections and increased numbers of viruses infecting the average host cell. Next, I address the effects of competition between viruses by modeling the population dynamics of a tripartite system, including host, virus, and virophage. I show the presence of virophage, a hyper-parasite of the virus, reduces the abundances of its competing virus while increasing the abundances of the mutual host. Lastly, I present and analyze experimental time series arising due to the infection of a host by a giant virus. By considering different ratios of inoculant viruses and hosts, I propose a novel method of viral growth with a strong dependence on the number of infecting viruses. Overall, I argue that multiple infections play a major role in shaping host and viral interactions in situ. Advisors/Committee Members: Weitz, Joshua S (advisor), Wiesenfeld, Kurt (committee member), Fenton, Flavio (committee member), Brown, Sam (committee member), Sullivan, Matthew (committee member).

Subjects/Keywords: Viral ecology; Multiple infections; Spatial dynamics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Taylor, B. (2016). Population dynamics of multiple viral infections. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/58625

Chicago Manual of Style (16th Edition):

Taylor, Bradford. “Population dynamics of multiple viral infections.” 2016. Doctoral Dissertation, Georgia Tech. Accessed July 23, 2019. http://hdl.handle.net/1853/58625.

MLA Handbook (7th Edition):

Taylor, Bradford. “Population dynamics of multiple viral infections.” 2016. Web. 23 Jul 2019.

Vancouver:

Taylor B. Population dynamics of multiple viral infections. [Internet] [Doctoral dissertation]. Georgia Tech; 2016. [cited 2019 Jul 23]. Available from: http://hdl.handle.net/1853/58625.

Council of Science Editors:

Taylor B. Population dynamics of multiple viral infections. [Doctoral Dissertation]. Georgia Tech; 2016. Available from: http://hdl.handle.net/1853/58625

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