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You searched for +publisher:"Georgia Tech" +contributor:("Dr. Buck, John"). One record found.

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Georgia Tech

1. Jung, Young Do. Microfabricated continuous flow separation and manipulation systems for human whole blood.

Degree: PhD, Electrical and Computer Engineering, 2010, Georgia Tech

The objective of the research in this dissertation is to develop microsystem based separation technologies for whole cell cancer analysis using human whole blood as the input sample. This research work is carried out with two different approaches; one based on a miniaturized cascade magnetophoresis system and a second based on dielectrophoresis. The miniaturized systems can be fabricated using MEMS technologies combined with plastic fabrication techniques. The design, fabrication, packaging, and characterization of several versions of the magnetophoresis and dielectrophoresis microsystems for whole cell cancer analysis in human whole blood sample are presented. The developed magnetophoresis systems have demonstrated improved throughput in the removal of RBC from a human whole blood sample and its application to the separation of tagged cancer cells based on their surface expression level of a specific protein. The dielectrophoresis microsystem has successfully shown the ability to steer a blood stream between two outlets and to separate WBCs or cancer cells from a human whole blood sample. The developed microsystem based separation technologies can be further applied to the development of integrated system for cancer detection and treatments. Advisors/Committee Members: Dr. Frazier, Albert (Committee Chair), Dr. Allen, Mark (Committee Member), Dr. Buck, John (Committee Member), Dr. Butera, Robert (Committee Member), Dr. Hesketh, Peter (Committee Member).

Subjects/Keywords: Magnetophoresis; Blood; Dielectrophoresis; Microsystem; Cancer; Separation (Technology); Blood cells; Hemapheresis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Jung, Y. D. (2010). Microfabricated continuous flow separation and manipulation systems for human whole blood. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/34003

Chicago Manual of Style (16th Edition):

Jung, Young Do. “Microfabricated continuous flow separation and manipulation systems for human whole blood.” 2010. Doctoral Dissertation, Georgia Tech. Accessed June 17, 2019. http://hdl.handle.net/1853/34003.

MLA Handbook (7th Edition):

Jung, Young Do. “Microfabricated continuous flow separation and manipulation systems for human whole blood.” 2010. Web. 17 Jun 2019.

Vancouver:

Jung YD. Microfabricated continuous flow separation and manipulation systems for human whole blood. [Internet] [Doctoral dissertation]. Georgia Tech; 2010. [cited 2019 Jun 17]. Available from: http://hdl.handle.net/1853/34003.

Council of Science Editors:

Jung YD. Microfabricated continuous flow separation and manipulation systems for human whole blood. [Doctoral Dissertation]. Georgia Tech; 2010. Available from: http://hdl.handle.net/1853/34003

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