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You searched for +publisher:"Georgia Tech" +contributor:("Donald Doyle"). Showing records 1 – 10 of 10 total matches.

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1. Guerrant, William. Targeted histone deacetylase inhibition.

Degree: PhD, Chemistry and Biochemistry, 2012, Georgia Tech

 Histone deacetylase (HDAC) inhibitors (HDACi) have demonstrated a wealth of biological effects, including anti-proliferative, anti-inflammatory, anti-parasitic, and cognition-enhancing activities. The recent FDA approvals of the… (more)

Subjects/Keywords: HDAC inhibitors; Drug design; Targeted drug delivery; HDAC; Histone deacetylase; Bifunctional inhibitors; Cancer therapy; Drug delivery systems; Cancer Treatment; Enzymes

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APA (6th Edition):

Guerrant, W. (2012). Targeted histone deacetylase inhibition. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/44907

Chicago Manual of Style (16th Edition):

Guerrant, William. “Targeted histone deacetylase inhibition.” 2012. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/44907.

MLA Handbook (7th Edition):

Guerrant, William. “Targeted histone deacetylase inhibition.” 2012. Web. 27 Nov 2020.

Vancouver:

Guerrant W. Targeted histone deacetylase inhibition. [Internet] [Doctoral dissertation]. Georgia Tech; 2012. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/44907.

Council of Science Editors:

Guerrant W. Targeted histone deacetylase inhibition. [Doctoral Dissertation]. Georgia Tech; 2012. Available from: http://hdl.handle.net/1853/44907

2. Wu, Di. Discovery and characterization of a signaling molecule regulating somatic embryogenesis in loblolly pine.

Degree: PhD, Chemistry and Biochemistry, 2008, Georgia Tech

 myo-Inositol-1,2,3,4,5,6-hexakisphosphate (InsP6), also called phytic acid, is ubiquitous in eukaryotic cells and the most abundant inositol phosphate derivative. Loblolly pine (LP, Pinus taeda) constitutes the… (more)

Subjects/Keywords: NMR; LC/MS; FPLC; Female gametophyte; Loblolly pine; Somatic embryogenesis; Myo-inositol hexakisphosphate; Loblolly pine; Somatic embryogenesis; Phytic acid

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APA (6th Edition):

Wu, D. (2008). Discovery and characterization of a signaling molecule regulating somatic embryogenesis in loblolly pine. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/28252

Chicago Manual of Style (16th Edition):

Wu, Di. “Discovery and characterization of a signaling molecule regulating somatic embryogenesis in loblolly pine.” 2008. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/28252.

MLA Handbook (7th Edition):

Wu, Di. “Discovery and characterization of a signaling molecule regulating somatic embryogenesis in loblolly pine.” 2008. Web. 27 Nov 2020.

Vancouver:

Wu D. Discovery and characterization of a signaling molecule regulating somatic embryogenesis in loblolly pine. [Internet] [Doctoral dissertation]. Georgia Tech; 2008. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/28252.

Council of Science Editors:

Wu D. Discovery and characterization of a signaling molecule regulating somatic embryogenesis in loblolly pine. [Doctoral Dissertation]. Georgia Tech; 2008. Available from: http://hdl.handle.net/1853/28252

3. Shaffer, Hally A. Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation.

Degree: PhD, Chemistry and Biochemistry, 2011, Georgia Tech

 Nuclear receptors are ligand-activated transcription factors that play significant roles in various biological processes within the body, such as cell development, hormone metabolism, reproduction, and… (more)

Subjects/Keywords: Nuclear receptors; Chemical complementation; Negative chemical complementation; Yeast-two hybrid selection; Pregnane X receptor; Estrogen receptor; Pregnane; Protein engineering; Nuclear receptors (Biochemistry); Transcription factors; Yeast Genetics

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APA (6th Edition):

Shaffer, H. A. (2011). Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/39620

Chicago Manual of Style (16th Edition):

Shaffer, Hally A. “Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation.” 2011. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/39620.

MLA Handbook (7th Edition):

Shaffer, Hally A. “Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation.” 2011. Web. 27 Nov 2020.

Vancouver:

Shaffer HA. Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation. [Internet] [Doctoral dissertation]. Georgia Tech; 2011. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/39620.

Council of Science Editors:

Shaffer HA. Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation. [Doctoral Dissertation]. Georgia Tech; 2011. Available from: http://hdl.handle.net/1853/39620


Georgia Tech

4. Urs, Aarti N. Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17.

Degree: MS, Biology, 2005, Georgia Tech

 Steroidogenic factor (SF1) is an orphan nuclear receptor that is essential for steroid hormone-biosynthesis and endocrine development. Recent studies have demonstrated that phospholipids are ligands… (more)

Subjects/Keywords: CYP17; Sphingosine; Phosphatidic acids; Steroidogenic factor 1; Transcription factors; Steroid hormones Synthesis; Sphingosine; Pregnenolone; Phospholipids; Ligands

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APA (6th Edition):

Urs, A. N. (2005). Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17. (Masters Thesis). Georgia Tech. Retrieved from http://hdl.handle.net/1853/7638

Chicago Manual of Style (16th Edition):

Urs, Aarti N. “Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17.” 2005. Masters Thesis, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/7638.

MLA Handbook (7th Edition):

Urs, Aarti N. “Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17.” 2005. Web. 27 Nov 2020.

Vancouver:

Urs AN. Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17. [Internet] [Masters thesis]. Georgia Tech; 2005. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/7638.

Council of Science Editors:

Urs AN. Reciprocal binding of sphingosine and phosphatidic acid to steroidogenic factor 1 regulates the transcription of CYP17. [Masters Thesis]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/7638


Georgia Tech

5. Thaler, Tracey Lyn. Search for Extraterrestrial Life using Chiral Molecules: Mandelate Racemase as a Test Case.

Degree: PhD, Chemistry and Biochemistry, 2007, Georgia Tech

 The possible existence of extraterrestrial life forms has been of interest to humans for many millennia. In the past few decades space travel has provided… (more)

Subjects/Keywords: Irreversible protein denaturation; Enzymatic reactivity at subzero temperatures; Enolase superfamily; Polarimetric assay

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APA (6th Edition):

Thaler, T. L. (2007). Search for Extraterrestrial Life using Chiral Molecules: Mandelate Racemase as a Test Case. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/14527

Chicago Manual of Style (16th Edition):

Thaler, Tracey Lyn. “Search for Extraterrestrial Life using Chiral Molecules: Mandelate Racemase as a Test Case.” 2007. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/14527.

MLA Handbook (7th Edition):

Thaler, Tracey Lyn. “Search for Extraterrestrial Life using Chiral Molecules: Mandelate Racemase as a Test Case.” 2007. Web. 27 Nov 2020.

Vancouver:

Thaler TL. Search for Extraterrestrial Life using Chiral Molecules: Mandelate Racemase as a Test Case. [Internet] [Doctoral dissertation]. Georgia Tech; 2007. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/14527.

Council of Science Editors:

Thaler TL. Search for Extraterrestrial Life using Chiral Molecules: Mandelate Racemase as a Test Case. [Doctoral Dissertation]. Georgia Tech; 2007. Available from: http://hdl.handle.net/1853/14527


Georgia Tech

6. Das, Prolay. Long-Range Charge Transfer in Plasmid DNA Condensates and DNA-Directed Assembly of Conducting Polymers.

Degree: PhD, Chemistry and Biochemistry, 2007, Georgia Tech

 Long-distance radical cation transport was studied in DNA condensates where linearized pUC19 plasmid was ligated to an oligomer and transformed into DNA condensates with spermidine.… (more)

Subjects/Keywords: DNA charge transfer; Conducting polymers; Radical cation; Self assembly; Conducting polymers; Charge tranfer in biology; Cations; DNA; Self-organizing systems

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APA (6th Edition):

Das, P. (2007). Long-Range Charge Transfer in Plasmid DNA Condensates and DNA-Directed Assembly of Conducting Polymers. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/19856

Chicago Manual of Style (16th Edition):

Das, Prolay. “Long-Range Charge Transfer in Plasmid DNA Condensates and DNA-Directed Assembly of Conducting Polymers.” 2007. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/19856.

MLA Handbook (7th Edition):

Das, Prolay. “Long-Range Charge Transfer in Plasmid DNA Condensates and DNA-Directed Assembly of Conducting Polymers.” 2007. Web. 27 Nov 2020.

Vancouver:

Das P. Long-Range Charge Transfer in Plasmid DNA Condensates and DNA-Directed Assembly of Conducting Polymers. [Internet] [Doctoral dissertation]. Georgia Tech; 2007. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/19856.

Council of Science Editors:

Das P. Long-Range Charge Transfer in Plasmid DNA Condensates and DNA-Directed Assembly of Conducting Polymers. [Doctoral Dissertation]. Georgia Tech; 2007. Available from: http://hdl.handle.net/1853/19856


Georgia Tech

7. McRae, Reagan. Investigating metal homeostasis in mammalian cells using high resolution imaging techniques.

Degree: PhD, Chemistry and Biochemistry, 2010, Georgia Tech

 The primary aim of the work presented in this thesis is to elucidate novel information regarding the uptake, storage, distributions, and functions of both copper… (more)

Subjects/Keywords: Microscopy; Imaging; Synchrotron based X-ray fluorescence; Copper; Zinc; Synchrotron radiation

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APA (6th Edition):

McRae, R. (2010). Investigating metal homeostasis in mammalian cells using high resolution imaging techniques. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/41197

Chicago Manual of Style (16th Edition):

McRae, Reagan. “Investigating metal homeostasis in mammalian cells using high resolution imaging techniques.” 2010. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/41197.

MLA Handbook (7th Edition):

McRae, Reagan. “Investigating metal homeostasis in mammalian cells using high resolution imaging techniques.” 2010. Web. 27 Nov 2020.

Vancouver:

McRae R. Investigating metal homeostasis in mammalian cells using high resolution imaging techniques. [Internet] [Doctoral dissertation]. Georgia Tech; 2010. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/41197.

Council of Science Editors:

McRae R. Investigating metal homeostasis in mammalian cells using high resolution imaging techniques. [Doctoral Dissertation]. Georgia Tech; 2010. Available from: http://hdl.handle.net/1853/41197


Georgia Tech

8. Gotz, Marion Gabriele. Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases.

Degree: PhD, Chemistry and Biochemistry, 2004, Georgia Tech

 Cysteine proteases are a class of proteolytic enzymes, which are involved in a series of metabolic and catabolic processes, such as protein turnover, digestion, blood… (more)

Subjects/Keywords: Allyl sulfone; Aza-peptide; Biosynthesis; Cysteine protease; Cysteine proteinases; Irreversible inhibitors; Protease inhibitors; Sulphones; Vinyl sulfone

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APA (6th Edition):

Gotz, M. G. (2004). Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/8072

Chicago Manual of Style (16th Edition):

Gotz, Marion Gabriele. “Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases.” 2004. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/8072.

MLA Handbook (7th Edition):

Gotz, Marion Gabriele. “Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases.” 2004. Web. 27 Nov 2020.

Vancouver:

Gotz MG. Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases. [Internet] [Doctoral dissertation]. Georgia Tech; 2004. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/8072.

Council of Science Editors:

Gotz MG. Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases. [Doctoral Dissertation]. Georgia Tech; 2004. Available from: http://hdl.handle.net/1853/8072


Georgia Tech

9. Roberts, Lezah Wilette. Effect of Netropsin on One-electron Oxidation of DNA.

Degree: PhD, Chemistry and Biochemistry, 2005, Georgia Tech

 One electron oxidation of DNA has been studied extensively over the years. When a charge is injected into a DNA duplex, it migrates through the… (more)

Subjects/Keywords: Photosensitizer; Charge transfer; Netropsin; TQ; DNA; Electron transfer; One-electron oxidation; Photosensitization, Biological; Charge transfer in biology; DNA Analysis; Oxidation, Physiological

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APA (6th Edition):

Roberts, L. W. (2005). Effect of Netropsin on One-electron Oxidation of DNA. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/7228

Chicago Manual of Style (16th Edition):

Roberts, Lezah Wilette. “Effect of Netropsin on One-electron Oxidation of DNA.” 2005. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/7228.

MLA Handbook (7th Edition):

Roberts, Lezah Wilette. “Effect of Netropsin on One-electron Oxidation of DNA.” 2005. Web. 27 Nov 2020.

Vancouver:

Roberts LW. Effect of Netropsin on One-electron Oxidation of DNA. [Internet] [Doctoral dissertation]. Georgia Tech; 2005. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/7228.

Council of Science Editors:

Roberts LW. Effect of Netropsin on One-electron Oxidation of DNA. [Doctoral Dissertation]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/7228


Georgia Tech

10. Watkins, Jason Derrick. X-ray structures of p22 c2 repressor-dna complexes: the mechansism of direct and indirect readout.

Degree: PhD, Chemistry and Biochemistry, 2008, Georgia Tech

 The P22 c2 repressor protein (P22R) binds to DNA sequence-specifically and helps direct the temperate lambdoid bacteriophage P22 to the lysogenic developmental pathway. To gain… (more)

Subjects/Keywords: P22 repressor; Direct readout; Indirect readout; Protein binding; DNA-protein interactions; Van der Waals forces

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APA (6th Edition):

Watkins, J. D. (2008). X-ray structures of p22 c2 repressor-dna complexes: the mechansism of direct and indirect readout. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/26709

Chicago Manual of Style (16th Edition):

Watkins, Jason Derrick. “X-ray structures of p22 c2 repressor-dna complexes: the mechansism of direct and indirect readout.” 2008. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/26709.

MLA Handbook (7th Edition):

Watkins, Jason Derrick. “X-ray structures of p22 c2 repressor-dna complexes: the mechansism of direct and indirect readout.” 2008. Web. 27 Nov 2020.

Vancouver:

Watkins JD. X-ray structures of p22 c2 repressor-dna complexes: the mechansism of direct and indirect readout. [Internet] [Doctoral dissertation]. Georgia Tech; 2008. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/26709.

Council of Science Editors:

Watkins JD. X-ray structures of p22 c2 repressor-dna complexes: the mechansism of direct and indirect readout. [Doctoral Dissertation]. Georgia Tech; 2008. Available from: http://hdl.handle.net/1853/26709

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