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You searched for +publisher:"Freie Universität Berlin" +contributor:("Prof. Dr. med. Berthold Rzany"). Showing records 1 – 3 of 3 total matches.

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Freie Universität Berlin

1. Roßner, Florian. results from the Injectable Filler Safety-Study (IFS-Study).

Degree: 2010, Freie Universität Berlin

BACKGROUND Injectable fillers are widely used in aesthetic medicine. Polylactic acid (PLA) is a semi-permanent filler that needs to be diluted with sterile water before injection. PLA, has been associated with an increased risk of adverse reactions, specifically nodule formation. OBJECTIVES To describe adverse reactions to PLA and potential risk factors based on a partly population-based registry over an eight year period. METHODS The Berlin registry is a partially population based registry where dermatologists, plastic surgeons and other specialists are contacted regularly and asked to report patients with adverse events to injectable fillers substances. Additional patients were derived from private practices outside of Berlin. The patients were assessed with a standardized questionnaire. The results were mainly analyzed by descriptive measures. RESULTS 22 patients (age, 47,82±12,65 years) with adverse reactions to PLA were included. The most frequent adverse reaction was nodule formation found in all patients. In 13 (59,1%) of the cases nodule formation was considered to be severe. Nodules appeared after a mean latency period of 6,00±5,84 months. The duration of the adverse reactions until the interview was 14,32±10,13 months. The frequency of patients with adverse events to PLA was found to decrease after new recommendation concerning the dilution of the product were launched. CONCLUSIONS Polylactic acid is an injectable filler substance that may cause subcutaneous nodules in treated patients. Our data supports a decreased risk of adverse reactions with an increased dilution. However, nodule formation still appears to be characteristic feature of PLA. Advisors/Committee Members: n (gender), Prof. Dr. med. Berthold Rzany Sc.M. (firstReferee), Prof. Dr. med. Christiane Bayerl (furtherReferee), Prof. Dr. med. Volker Steinkraus (furtherReferee).

Subjects/Keywords: poly-lactid-acid; adverse events; adverse reactions; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Roßner, F. (2010). results from the Injectable Filler Safety-Study (IFS-Study). (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-12148

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Roßner, Florian. “results from the Injectable Filler Safety-Study (IFS-Study).” 2010. Thesis, Freie Universität Berlin. Accessed April 07, 2020. http://dx.doi.org/10.17169/refubium-12148.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Roßner, Florian. “results from the Injectable Filler Safety-Study (IFS-Study).” 2010. Web. 07 Apr 2020.

Vancouver:

Roßner F. results from the Injectable Filler Safety-Study (IFS-Study). [Internet] [Thesis]. Freie Universität Berlin; 2010. [cited 2020 Apr 07]. Available from: http://dx.doi.org/10.17169/refubium-12148.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Roßner F. results from the Injectable Filler Safety-Study (IFS-Study). [Thesis]. Freie Universität Berlin; 2010. Available from: http://dx.doi.org/10.17169/refubium-12148

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Freie Universität Berlin

2. Pathirana, Delano. Methodical development of evidence based guidelines in dermatology and occurring challenges.

Degree: 2012, Freie Universität Berlin

Background: Evidence based guidelines can improve medical healthcare but the development is a demanding and time consuming process. Therefore it is important to share the knowledge about the development of such guidelines. Objectives: To present the methodical development process of evidence based guidelines by the means of the publications on the European evidence based guidelines on the systemic therapy of plaque psoriasis, the method report of these guidelines and the evaluation of the German evidence based guidelines on psoriasis, and to critically appraise this process. .Methods: A search for national evidence based guidelines and an additional systematic search and evaluation of new literature was performed for the European guidelines. Further steps included a structured consensus process to develop the recommendations, as well as several internal and external reviews. For the implementation of the German guidelines 223 dermatologists of Berlin and surrounding Brandenburg were invited for an implementation workshop. Results: Three national guidelines and a total of 114 studies served as base for the efficacy chapters of the European guidelines. The consensus process includes a structured consensus meeting and a DELPHI procedure. The external review was performed by European national dermatological societies, the European Dermatology Forum, the European Academy of Dermatology and Venereology and the Union Europeenne des Medicins Specialistes. Concerning the implementation of the German guidelines 27% of the invited dermatologists took part in the two- hour implementation workshop. A total of 79% felt that guidelines would be helpful in improving physicians’ confidence and would ultimately lead to an increased use of systemic treatments. Conclusion: The development of evidence based guidelines can improve medical healthcare. Therefore the acceptance of the users is required. A good precondition for acceptance is a high methodical quality of the guidelines (e.g. evidence and consensus based), transparency in the development process (e.g. by a method report) and an implementation besides publication of the guidelines. Advisors/Committee Members: m (gender), Prof. Dr. med. Berthold Rzany (firstReferee), Prof. Dr. med. Matthias Augustin, Prof. Dr. med. Johannes Wohlrab (furtherReferee).

Subjects/Keywords: S3 guidelines; evidence based guidelines; method report; dermatology; methodology; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Pathirana, D. (2012). Methodical development of evidence based guidelines in dermatology and occurring challenges. (Thesis). Freie Universität Berlin. Retrieved from https://refubium.fu-berlin.de/handle/fub188/12960

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Pathirana, Delano. “Methodical development of evidence based guidelines in dermatology and occurring challenges.” 2012. Thesis, Freie Universität Berlin. Accessed April 07, 2020. https://refubium.fu-berlin.de/handle/fub188/12960.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Pathirana, Delano. “Methodical development of evidence based guidelines in dermatology and occurring challenges.” 2012. Web. 07 Apr 2020.

Vancouver:

Pathirana D. Methodical development of evidence based guidelines in dermatology and occurring challenges. [Internet] [Thesis]. Freie Universität Berlin; 2012. [cited 2020 Apr 07]. Available from: https://refubium.fu-berlin.de/handle/fub188/12960.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pathirana D. Methodical development of evidence based guidelines in dermatology and occurring challenges. [Thesis]. Freie Universität Berlin; 2012. Available from: https://refubium.fu-berlin.de/handle/fub188/12960

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Freie Universität Berlin

3. Zielke, Hendrik. Adverse Effects of Non-Biodegradable Injectable Fillers in Aesthetic Dermatology - Results of the Injectable-Filler-Safety-Study.

Degree: 2008, Freie Universität Berlin

Background Injectable fillers are widely used in Aesthetic Medicine. Although most materials are considered to be safe, adverse events occur and can be difficult to treat. Our knowledge on frequency and potential risk factors is limited. We report on the results of the IFS-Study, a partly population based case series with the aim to describe adverse reactions to these substances. Methods Dermatologists, plastic surgeons and maxillo-facial surgeons in Berlin were asked to report patients with adverse reactions to injectable filler substances. Additional cases were obtained from a private practice in Munich. A standardized questionnaire was used to assess all data. Adverse reactions were evaluated by patient as well as area treated. All data was analyzed by descriptive measures. Results 56 patients (age 48 ± 11.2 (sd) years) who had been treated with 9 different fillers were assessed. In 48 patients treated with only one filler 167 areas had been treated. In 129 (77.3%) areas adverse reactions occurred. Mean time until adverse reaction was 12.2 ± 15.6 (sd) months after injection. Adverse reactions to biodegradable fillers occurred after 4.9 ± 5.8 (sd) months, reactions to non-biodegradable fillers after 18.3 ± 19.0 (sd) months (p=0.005). As adverse events continuing pain, swelling, nodules, pigmentation, abscedation and erythema were found. For five different substance classes characteristic side effect profiles could be described. Conclusion Adverse reactions can be documented for all injectable fillers. Time until reaction as well as type of reaction, however, vary between different fillers. Further research is necessary to evaluate potential risk factors. Advisors/Committee Members: n (gender), Herr Prof. Dr. med. Berthold Rzany Sc.M. (firstReferee), Frau Prof. Dr. med. Martina Kerscher (furtherReferee), Herr Prof. Dr. med. Rolf-Markus Szeimies (furtherReferee).

Subjects/Keywords: aesthetic dermatology injectable permanent fillers; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Zielke, H. (2008). Adverse Effects of Non-Biodegradable Injectable Fillers in Aesthetic Dermatology - Results of the Injectable-Filler-Safety-Study. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-9406

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Zielke, Hendrik. “Adverse Effects of Non-Biodegradable Injectable Fillers in Aesthetic Dermatology - Results of the Injectable-Filler-Safety-Study.” 2008. Thesis, Freie Universität Berlin. Accessed April 07, 2020. http://dx.doi.org/10.17169/refubium-9406.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Zielke, Hendrik. “Adverse Effects of Non-Biodegradable Injectable Fillers in Aesthetic Dermatology - Results of the Injectable-Filler-Safety-Study.” 2008. Web. 07 Apr 2020.

Vancouver:

Zielke H. Adverse Effects of Non-Biodegradable Injectable Fillers in Aesthetic Dermatology - Results of the Injectable-Filler-Safety-Study. [Internet] [Thesis]. Freie Universität Berlin; 2008. [cited 2020 Apr 07]. Available from: http://dx.doi.org/10.17169/refubium-9406.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zielke H. Adverse Effects of Non-Biodegradable Injectable Fillers in Aesthetic Dermatology - Results of the Injectable-Filler-Safety-Study. [Thesis]. Freie Universität Berlin; 2008. Available from: http://dx.doi.org/10.17169/refubium-9406

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.