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You searched for +publisher:"Freie Universität Berlin" +contributor:("Dr. rer. nat. S. Amasheh"). One record found.

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Freie Universität Berlin

1. Freund, Aresu. Standard value survey of intraocular pressure and ocular pulse amplitude with the PASCAL®-System and evaluation of dependent variables.

Degree: 2011, Freie Universität Berlin

Worldwide ophthalmologists are daily confronted with eye diseases as a result of cardiovascular diseases with associated deterioration of the eye blood circulation (for example systemic arterial hypertension, diabetes mellitus, peripheral arterial disease and many more). Even in the pathogenesis of glaucoma the blood circulation of the eye or the optic nerve head plays an equally important role as the intraocular pressure. As with pressure in the systemic circulation, pressure and blood flow conditions in the eye are also dynamic variables: The eye pressure rises and falls simultaneously with the heart's rhythm, and presents itself quantitatively as systolic and diastolic pressure in the eye – the difference between the systolic and diastolic eye pressure is called the ocular pulse amplitude. A few years ago quantification of these synchronised pulse pressure fluctuations was not possible without much effort for examiner and patient. Since 2004 the PASCAL® dynamic contour tonometer has become available nationwide in Germany. For the first time the diastolic pressure in the eye and the ocular pulse amplitude are relatively simple to measure in a tolerable time frame for examiner and patient. A particular advantage of the modern PASCAL® System, compared with other previously existing tonometers, is it’s independence from corneal conditions. This means the real intraocular pressure can be measured non-invasive for the first time. However, the assessment of the ocular pulse amplitude proves to be problematic, because uniformly accepted standard values are not available. The aim of this study was primarily the creation of standard values for the ocular pulse amplitude, measured with the PASCAL® System. In addition, the mean difference of ocular pulse amplitude within a pair of eyes should be determined and the results of the dynamic contour tonometry should be investigated in relation to the factors which could influence them. With the acceptance of the ethics committee a healthy population of 208 subjects were recruited (m: f = 104:104) in the Schlosspark-Clinic Berlin. Statistics based on anamnestic data, blood pressure, pulse rate, visual acuity and refraction, ocular axis length, anterior chamber depth, corneal thickness/ radius, results of ophthalmologic function tests (motility, pupil reaction) and examinations of the anterior and posterior eye segments with the slit lamp, intraocular pressure measured by Goldmann applanation tonometry and ocular pressure and ocular pulse amplitude using PASCAL® dynamic contour tonometry. Our studies showed a mean difference in ocular pulse amplitude within a pair of eyes of 0.12 ± 0.04 mm Hg (mean value with confidence interval P = 95%) with little gender difference (mean m: f = 0.13:0.10 mm Hg) . Evaluations of other statistical data were carried out randomly according to statistic standards, so that in each case either a right or left eye was randomly chosen per person for the study. Due to a statistically significant “tonography effect” on the observed pressure data only the… Advisors/Committee Members: w (gender), Prof. Dr. med. A. Joussen (inspector), Dr. rer. nat. S. Amasheh (inspector), Dr. med. W. Noske (inspector), Prof. Dr. med. C. Erb (firstReferee), Prof. Dr. Dr. med. P. Rieck (furtherReferee), Prof. Dr. med. M. Klemm (furtherReferee).

Subjects/Keywords: ocular pulse amplitude; OPA; glaucoma; dynamic contour tonometry; DCT; PASCAL; tonometer; intraocular pressure; IOP; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit

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APA (6th Edition):

Freund, A. (2011). Standard value survey of intraocular pressure and ocular pulse amplitude with the PASCAL®-System and evaluation of dependent variables. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-10701

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Freund, Aresu. “Standard value survey of intraocular pressure and ocular pulse amplitude with the PASCAL®-System and evaluation of dependent variables.” 2011. Thesis, Freie Universität Berlin. Accessed November 14, 2019. http://dx.doi.org/10.17169/refubium-10701.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Freund, Aresu. “Standard value survey of intraocular pressure and ocular pulse amplitude with the PASCAL®-System and evaluation of dependent variables.” 2011. Web. 14 Nov 2019.

Vancouver:

Freund A. Standard value survey of intraocular pressure and ocular pulse amplitude with the PASCAL®-System and evaluation of dependent variables. [Internet] [Thesis]. Freie Universität Berlin; 2011. [cited 2019 Nov 14]. Available from: http://dx.doi.org/10.17169/refubium-10701.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Freund A. Standard value survey of intraocular pressure and ocular pulse amplitude with the PASCAL®-System and evaluation of dependent variables. [Thesis]. Freie Universität Berlin; 2011. Available from: http://dx.doi.org/10.17169/refubium-10701

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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