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You searched for +publisher:"Florida International University" +contributor:("George T. Duncan"). Showing records 1 – 3 of 3 total matches.

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Florida International University

1. Gayden, Tenzin. Genetic Diversity in the Himalayan Populations of Nepal and Tibet.

Degree: PhD, Biology, 2012, Florida International University

The Himalayan Mountain range encompasses an unparalleled landscape featuring some of the planet’s highest peaks, including Mount Everest. In the heart of this massive orographic barrier lies Nepal, sandwiched in the historically geostrategic position between the Tibetan plateau to the north and India in the south. Until recently, Nepalese and Tibetan populations remained poorly characterized genetically, partly because of their inaccessible geographical locations. In the present study, the genetic diversity of these two Himalayan populations is evaluated using different marker systems, including mitochondrial DNA (mtDNA) and Short Tandem Repeats (STRs) in the autosomes as well as on the Y-chromosome (Y-STR). While autosomal STRs are distributed throughout the genome and are biparentally inherited, the Y-chromosome and mtDNA are haploid markers and provide the paternal and maternal histories of the population, respectively. Fifteen autosomal STR loci were typed in 341 unrelated individuals from three Nepalese populations (188), namely Tamang (45), Newar (66) and Kathmandu (77), and a general collection from Tibet (153). These samples were also sequenced for the mtDNA control region and all of them were subsequently assigned to 75 different mtDNA haplogroups and sub-haplogroups by screening their diagnostic sites in the coding region using Restriction Fragment Length Polymorphism analysis and/or sequencing, thus achieving an unprecedented level of resolution. The results from the autosomal and mtDNA data suggest a Northeast Asian origin for the Himalayan populations, with significant genetic influence from the Indian subcontinent in Kathmandu and Newar, corroborating our previous Y-chromosome study. In contrast, Tibet displays a limited Indian component, suggesting that the Himalayan massif acted as a natural barrier for gene flow from the south. The presence of ancient Indian mtDNA lineages in Nepal implies that the region may have been inhabited by the earliest settlers who initially populated South Asia. In addition, seventeen Y-STR loci were analyzed in 350 Tibetan males from three culturally defined regions of historical Tibet: Amdo (88), Kham (109) and U-Tsang (153). The results demonstrate that the 17 Y-STR loci studied are highly polymorphic in all the three Tibetan populations examined and hence are useful for forensic cases, paternity testing and population genetic studies. Advisors/Committee Members: Rene J. Herrera, George T. Duncan, DeEtta K. Mills, Bruce R. McCord, Timothy M. Collins.

Subjects/Keywords: Himalayas; Nepal; Tibet; Y-chromosome; mtDNA; Y-STR; Autosomal STR

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APA (6th Edition):

Gayden, T. (2012). Genetic Diversity in the Himalayan Populations of Nepal and Tibet. (Doctoral Dissertation). Florida International University. Retrieved from https://digitalcommons.fiu.edu/etd/580 ; 10.25148/etd.FI12042312 ; FI12042312

Chicago Manual of Style (16th Edition):

Gayden, Tenzin. “Genetic Diversity in the Himalayan Populations of Nepal and Tibet.” 2012. Doctoral Dissertation, Florida International University. Accessed September 20, 2020. https://digitalcommons.fiu.edu/etd/580 ; 10.25148/etd.FI12042312 ; FI12042312.

MLA Handbook (7th Edition):

Gayden, Tenzin. “Genetic Diversity in the Himalayan Populations of Nepal and Tibet.” 2012. Web. 20 Sep 2020.

Vancouver:

Gayden T. Genetic Diversity in the Himalayan Populations of Nepal and Tibet. [Internet] [Doctoral dissertation]. Florida International University; 2012. [cited 2020 Sep 20]. Available from: https://digitalcommons.fiu.edu/etd/580 ; 10.25148/etd.FI12042312 ; FI12042312.

Council of Science Editors:

Gayden T. Genetic Diversity in the Himalayan Populations of Nepal and Tibet. [Doctoral Dissertation]. Florida International University; 2012. Available from: https://digitalcommons.fiu.edu/etd/580 ; 10.25148/etd.FI12042312 ; FI12042312


Florida International University

2. Gayden, Tenzin. Y-chromosome polymorphisms in the Himalayas.

Degree: MS, Biology, 2006, Florida International University

In the present study, high resolution Y-chromosome SNP analyses were employed to investigate the genetic origins of three distinct groups from Nepal namely, the general population of Kathmandu, Newar, and Tamang, as well as a collection from Tibet. The results suggest that the Tibetans and Nepalese are descendants of Tibeto-Burman speaking groups originating in Northeast Asia. With the exception of Tamang, both Newar and Kathmandu exhibit considerable similarities to Indian Y haplogroup substructure. These results suggest recent gene flow from the Indian subcontinent, a conclusion that is also supported by the admixture analysis. In contrast, while YAP+ , a genetic signature of Central Asian origin, is completely absent in Nepal, it accounts for more than fifty percent of Tibetan Y-chromosome. Low frequencies of haplogroup R lineages in Tibet reflect limited gene flow from India most likely due to the Himalayan mountain range to the south. Advisors/Committee Members: Rene J. Herrera, George T. Duncan, Timothy M. Collins.

Subjects/Keywords: Biology; Life Sciences

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Gayden, T. (2006). Y-chromosome polymorphisms in the Himalayas. (Thesis). Florida International University. Retrieved from https://digitalcommons.fiu.edu/etd/3587 ; FI15101545

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Gayden, Tenzin. “Y-chromosome polymorphisms in the Himalayas.” 2006. Thesis, Florida International University. Accessed September 20, 2020. https://digitalcommons.fiu.edu/etd/3587 ; FI15101545.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Gayden, Tenzin. “Y-chromosome polymorphisms in the Himalayas.” 2006. Web. 20 Sep 2020.

Vancouver:

Gayden T. Y-chromosome polymorphisms in the Himalayas. [Internet] [Thesis]. Florida International University; 2006. [cited 2020 Sep 20]. Available from: https://digitalcommons.fiu.edu/etd/3587 ; FI15101545.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gayden T. Y-chromosome polymorphisms in the Himalayas. [Thesis]. Florida International University; 2006. Available from: https://digitalcommons.fiu.edu/etd/3587 ; FI15101545

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Florida International University

3. Cadenas, Alicia M. Y-chromosome polymorphisms in southern Arabia.

Degree: MS, Forensic Science, 2006, Florida International University

In order to explore south Arabia's role in the migratory episodes leaving Africa to Eurasia and back, high-resolution Y-chromosome analyses of males from the United Arab Emirates (164), Qatar (72) and Yemen (62) were performed. The distribution of specific haplogroups (E3bl-M35 and J1-M267) and their microsatellite-based age estimates in southern Arabia offer additional insight on their dissemination. With the exception of Yemen, southern Arabia displays high diversity in its Y-haplogroup substructure and share similarities with populations along the eastern coast of the Gulf of Oman, possibly serving as a coastal corridor for migrations. Elevated rates of consanguinity may have had an impact in Yemen and Qatar, which experience deficiencies in their ratios of observed to expected heterozygosity at 15 hypervariable autosomal STR loci. Higher diversity along the Gulf of Oman may be due to trade emanating from the kingdom of Oman involving East Africa, southern Pakistan and western India. Advisors/Committee Members: Rene J. Herrera, George T. Duncan, Fernando G. Noriega.

Subjects/Keywords: Forensic Science and Technology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Cadenas, A. M. (2006). Y-chromosome polymorphisms in southern Arabia. (Thesis). Florida International University. Retrieved from https://digitalcommons.fiu.edu/etd/1962 ; 10.25148/etd.FI14052526 ; FI14052526

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Cadenas, Alicia M. “Y-chromosome polymorphisms in southern Arabia.” 2006. Thesis, Florida International University. Accessed September 20, 2020. https://digitalcommons.fiu.edu/etd/1962 ; 10.25148/etd.FI14052526 ; FI14052526.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Cadenas, Alicia M. “Y-chromosome polymorphisms in southern Arabia.” 2006. Web. 20 Sep 2020.

Vancouver:

Cadenas AM. Y-chromosome polymorphisms in southern Arabia. [Internet] [Thesis]. Florida International University; 2006. [cited 2020 Sep 20]. Available from: https://digitalcommons.fiu.edu/etd/1962 ; 10.25148/etd.FI14052526 ; FI14052526.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cadenas AM. Y-chromosome polymorphisms in southern Arabia. [Thesis]. Florida International University; 2006. Available from: https://digitalcommons.fiu.edu/etd/1962 ; 10.25148/etd.FI14052526 ; FI14052526

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.