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You searched for +publisher:"Delft University of Technology" +contributor:("Van Dijken, J.P."). Showing records 1 – 3 of 3 total matches.

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Delft University of Technology

1. Kuijper, S.M. Engineering of Saccharomyces cerevisiae for the production of fuel ethanol from xylose.

Degree: 2006, Delft University of Technology

For various reasons mankind is looking for alternatives for fossil fuels. One of these alternatives is ethanol made from plant biomass. However, the plant material when broken down by hydrolysis into its sugar monomers contains a significant amount of xylose, a 5-carbon-sugar or pentose. Contrary to the sugars with 6 carbon atoms (hexoses) wild type baker's yeast does not convert xylose into ethanol. The most widely used method for ethanol production is fermentation with Saccharomyces cerevisiae better known as baker's yeast. In order to obtain an economically viable process for fuel ethanol production, an organism is required that can also ferment the pentose fraction of the biomass hydrolysate to ethanol. Over the last three decades people have tried to introduce xylose metabolism in baker's yeast using two strategies. 1) The introduction of a bacterial xylose isomerase gene and 2) The introduction of the fungal genes coding for xylose reductase and xylitol dehydrogenase. Both strategies have been unsuccessful. The work in this thesis describes a major breakthrough in the anaerobic fermentation of xylose by bakers yeast. The breakthrough came with the discovery of the first fungal xylose isomerase, in the obligate anaerobic fungus Piromyces sp. E2. Contrary to the bacterial genes, this fungal xylose isomerase could be functionally expressed in Saccharomyces cerevisiae at high levels. The introduction of the isomerase into the genome enabled bakers yeast to grow aerobically on xylose as the sole carbon source. Eventually, using a strategy of combined metabolic and evolutionary engineering, a yeast strain was obtained with an anaerobic growth rate on xylose of 0.12 h-1 and a xylose consumption rate of 1.4 grams xylose per gram biomass per hour. The final conclusion that can be drawn from this work is that the kinetics of xylose fermentation are no longer a bottleneck in the industrial production of bioethanol with yeasts. Advisors/Committee Members: Pronk, J.T., van Dijken, J.P..

Subjects/Keywords: xylose isomerase; piromyces; fermentation; pentose; yeast; bioethanol; lignocellulose; metabolic engineering; evolutionary engineering; pentose phosphate pathway; hemicellulose

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APA (6th Edition):

Kuijper, S. M. (2006). Engineering of Saccharomyces cerevisiae for the production of fuel ethanol from xylose. (Doctoral Dissertation). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586

Chicago Manual of Style (16th Edition):

Kuijper, S M. “Engineering of Saccharomyces cerevisiae for the production of fuel ethanol from xylose.” 2006. Doctoral Dissertation, Delft University of Technology. Accessed November 22, 2019. http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586.

MLA Handbook (7th Edition):

Kuijper, S M. “Engineering of Saccharomyces cerevisiae for the production of fuel ethanol from xylose.” 2006. Web. 22 Nov 2019.

Vancouver:

Kuijper SM. Engineering of Saccharomyces cerevisiae for the production of fuel ethanol from xylose. [Internet] [Doctoral dissertation]. Delft University of Technology; 2006. [cited 2019 Nov 22]. Available from: http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586.

Council of Science Editors:

Kuijper SM. Engineering of Saccharomyces cerevisiae for the production of fuel ethanol from xylose. [Doctoral Dissertation]. Delft University of Technology; 2006. Available from: http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; urn:NBN:nl:ui:24-uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586 ; http://resolver.tudelft.nl/uuid:6c9304a5-9472-4c9b-b8f9-ac966dad3586


Delft University of Technology

2. Geertman, J.M.A. Engineering of redox metabolism in yeast: New strategies for improved glycerol production.

Degree: 2006, Delft University of Technology

Abstract not available Advisors/Committee Members: Pronk, J.T., Van Dijken, J.P..

Subjects/Keywords: metabolic engineering; biotechnology

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APA (6th Edition):

Geertman, J. M. A. (2006). Engineering of redox metabolism in yeast: New strategies for improved glycerol production. (Doctoral Dissertation). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835

Chicago Manual of Style (16th Edition):

Geertman, J M A. “Engineering of redox metabolism in yeast: New strategies for improved glycerol production.” 2006. Doctoral Dissertation, Delft University of Technology. Accessed November 22, 2019. http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835.

MLA Handbook (7th Edition):

Geertman, J M A. “Engineering of redox metabolism in yeast: New strategies for improved glycerol production.” 2006. Web. 22 Nov 2019.

Vancouver:

Geertman JMA. Engineering of redox metabolism in yeast: New strategies for improved glycerol production. [Internet] [Doctoral dissertation]. Delft University of Technology; 2006. [cited 2019 Nov 22]. Available from: http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835.

Council of Science Editors:

Geertman JMA. Engineering of redox metabolism in yeast: New strategies for improved glycerol production. [Doctoral Dissertation]. Delft University of Technology; 2006. Available from: http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; urn:NBN:nl:ui:24-uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835 ; http://resolver.tudelft.nl/uuid:827b0532-2a73-4cd4-bf2a-be980b2a4835


Delft University of Technology

3. Van Maris, A.J.A. Metabolic engineering of pyruvate metabolism in Saccharomyces cerevisiae.

Degree: 2004, Delft University of Technology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Van Maris, A. J. A. (2004). Metabolic engineering of pyruvate metabolism in Saccharomyces cerevisiae. (Doctoral Dissertation). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90

Chicago Manual of Style (16th Edition):

Van Maris, A J A. “Metabolic engineering of pyruvate metabolism in Saccharomyces cerevisiae.” 2004. Doctoral Dissertation, Delft University of Technology. Accessed November 22, 2019. http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90.

MLA Handbook (7th Edition):

Van Maris, A J A. “Metabolic engineering of pyruvate metabolism in Saccharomyces cerevisiae.” 2004. Web. 22 Nov 2019.

Vancouver:

Van Maris AJA. Metabolic engineering of pyruvate metabolism in Saccharomyces cerevisiae. [Internet] [Doctoral dissertation]. Delft University of Technology; 2004. [cited 2019 Nov 22]. Available from: http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90.

Council of Science Editors:

Van Maris AJA. Metabolic engineering of pyruvate metabolism in Saccharomyces cerevisiae. [Doctoral Dissertation]. Delft University of Technology; 2004. Available from: http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; urn:NBN:nl:ui:24-uuid:f94de7e5-f13d-494a-899e-57a18fda0c90 ; http://resolver.tudelft.nl/uuid:f94de7e5-f13d-494a-899e-57a18fda0c90

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