Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

You searched for +publisher:"Delft University of Technology" +contributor:("Grootjans, Willem"). Showing records 1 – 2 of 2 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


Delft University of Technology

1. Ghesquière-Diérickx, Laura (author). Improvement of tumour heterogeneity quantification in PET images: A study to design and develop a new PET heterogeneous phantom.

Degree: 2017, Delft University of Technology

In medical images intratumour heterogeneity well translates specific cancer cells properties in a fast and non-invasive way. Medical community and researchers have developed proper tools (texture features, shape features…) permitting the quantification and the analysis of this tumour heterogeneity in particular in PET images. Yet so far, both doctors and researchers have mainly focused on the use of those tools before assessing their relevance and robustness. In this study, a new heterogeneous PET phantom allowing an extensive understanding of the key concept of heterogeneity quantification in PET images is designed and partially developed. This phantom aims at representing a complex enough environment mimicking clinical conditions to properly challenge PET heterogeneity data extraction and quantification methods further than commercial phantom already do. This study focuses, first, on defining sound specifications, design methodology and manufacturing method for this new object. Second, the study focuses on designing and developing the defined solution. Third, a proof-of-concept analysis is conducted within the study to test and validate the developed PET phantom prototype. It can be concluded that the produced PET phantom was successfully designed and developed and can be used by other operators; yet, there is still room for improvement. Finally, besides developing a novel PET phantom, this study yields recommendations to improve the work done toward a more handy, flexible and realistic tool.

Biomedical Engineering

Advisors/Committee Members: Schaart, Dennis (mentor), Grootjans, Willem (mentor), Lathouwers, Danny (graduation committee), Zadpoor, Amir (graduation committee), Delft University of Technology (degree granting institution).

Subjects/Keywords: pet; phantom; heterogeneity; Positron emission tomography

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Ghesquière-Diérickx, L. (. (2017). Improvement of tumour heterogeneity quantification in PET images: A study to design and develop a new PET heterogeneous phantom. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:0183c922-76a4-4507-96dd-38362e27da0a

Chicago Manual of Style (16th Edition):

Ghesquière-Diérickx, Laura (author). “Improvement of tumour heterogeneity quantification in PET images: A study to design and develop a new PET heterogeneous phantom.” 2017. Masters Thesis, Delft University of Technology. Accessed April 20, 2021. http://resolver.tudelft.nl/uuid:0183c922-76a4-4507-96dd-38362e27da0a.

MLA Handbook (7th Edition):

Ghesquière-Diérickx, Laura (author). “Improvement of tumour heterogeneity quantification in PET images: A study to design and develop a new PET heterogeneous phantom.” 2017. Web. 20 Apr 2021.

Vancouver:

Ghesquière-Diérickx L(. Improvement of tumour heterogeneity quantification in PET images: A study to design and develop a new PET heterogeneous phantom. [Internet] [Masters thesis]. Delft University of Technology; 2017. [cited 2021 Apr 20]. Available from: http://resolver.tudelft.nl/uuid:0183c922-76a4-4507-96dd-38362e27da0a.

Council of Science Editors:

Ghesquière-Diérickx L(. Improvement of tumour heterogeneity quantification in PET images: A study to design and develop a new PET heterogeneous phantom. [Masters Thesis]. Delft University of Technology; 2017. Available from: http://resolver.tudelft.nl/uuid:0183c922-76a4-4507-96dd-38362e27da0a


Delft University of Technology

2. Oosterveer, Timo (author). Invasive Coronary Artery Imaging Using Optical Coherence Tomography: A Cost-effectiveness and Implementation Process Analysis.

Degree: 2020, Delft University of Technology

The aim of this project was the implementation of optical coherence tomography (OCT), an invasive intracoronary imaging (ICI) tool used for the visualization of coronary arteries. The implementation was performed in a structured manner by: (1) A literature review into the current applications of OCT in relation to current standards; (2) A thesis feasibility study into clinical practices, professional views and other processes regarding ICI; (3) A Master’s thesis including a cost-effectiveness analysis (CEA) and the actual implementation of OCT at the department. The project started with a literature review about the current applications of OCT in relation to intravascular ultrasound (IVUS) and coronary angiography (CAG). The literature review has been published in Cardiology and Therapy. In general, OCT-guidance seems to contribute to favorable clinical outcomes compared with CAG-guidance alone. However, OCT-guidance results in similar clinical outcomes as IVUS-guidance. OCT could be considered for lumen assessment and stent related morphology in more complex cases in which CAG interpretation remains uncertain. Since OCT and IVUS have distinct characteristics, these techniques are complementary and should be considered carefully for each patient case based on the benefits and limitations of both techniques. The thesis feasibility study aimed at acquiring insights into the clinical practices, the different views, and other processes (data, training, etcetera) related to ICI at the LUMC and other medical centers. This was achieved by observing clinical practices at the LUMC and other medical centers, and by interviewing clinicians and technicians at those centers. Both the literature review and the feasibility study provided extensive insights in current practices and controversies regarding ICI. Such insights were essential before implementation of OCT. These insights were used to carefully execute the implementation, while accounting for the interests of all stakeholders as much as possible. In addition, the knowledge gained from the literature review and feasibility study were used as input for the master’s thesis. The master’s thesis included a health economic evaluation comparing cost-effectiveness of OCT with IVUS and CAG, and the actual implementation of OCT at the department. The CEA was performed using the concept of Markov modelling. In general, OCT along with CAG was a more cost-effective intracoronary treatment strategy than IVUS along with CAG for patients with CAD. However, the gain in QALYs and reduction in costs were limited. Both IVUS and OCT outperform CAG alone in terms of cost-effectiveness. With this thesis the current applications of OCT in relation to IVUS and CAG were identified, insights into different views and practices regarding ICI in the interventional cardiology domain were obtained and the cost-effectiveness of OCT-guided PCI compared with IVUS-guided PCI and PCI solely guided by CAG was assessed. In addition, OCT was implemented at the department of interventional cardiology of the… Advisors/Committee Members: Scherptong, Roderick (mentor), van der Meer, Sander (mentor), van den Akker-van Marle, Elske (graduation committee), Harlaar, Jaap (graduation committee), Grootjans, Willem (graduation committee), Delft University of Technology (degree granting institution), Leiden University (degree granting institution), Erasmus Universiteit Rotterdam (degree granting institution).

Subjects/Keywords: Coronary artery disease; Percutaneous coronary intervention; Intracoronary imaging; Optical Coherence Tomography; Intravascular ultrasound; Cost-effectiveness; Implementation

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Oosterveer, T. (. (2020). Invasive Coronary Artery Imaging Using Optical Coherence Tomography: A Cost-effectiveness and Implementation Process Analysis. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:188df1a0-a81d-4b9c-9f77-110f3b2aff6c

Chicago Manual of Style (16th Edition):

Oosterveer, Timo (author). “Invasive Coronary Artery Imaging Using Optical Coherence Tomography: A Cost-effectiveness and Implementation Process Analysis.” 2020. Masters Thesis, Delft University of Technology. Accessed April 20, 2021. http://resolver.tudelft.nl/uuid:188df1a0-a81d-4b9c-9f77-110f3b2aff6c.

MLA Handbook (7th Edition):

Oosterveer, Timo (author). “Invasive Coronary Artery Imaging Using Optical Coherence Tomography: A Cost-effectiveness and Implementation Process Analysis.” 2020. Web. 20 Apr 2021.

Vancouver:

Oosterveer T(. Invasive Coronary Artery Imaging Using Optical Coherence Tomography: A Cost-effectiveness and Implementation Process Analysis. [Internet] [Masters thesis]. Delft University of Technology; 2020. [cited 2021 Apr 20]. Available from: http://resolver.tudelft.nl/uuid:188df1a0-a81d-4b9c-9f77-110f3b2aff6c.

Council of Science Editors:

Oosterveer T(. Invasive Coronary Artery Imaging Using Optical Coherence Tomography: A Cost-effectiveness and Implementation Process Analysis. [Masters Thesis]. Delft University of Technology; 2020. Available from: http://resolver.tudelft.nl/uuid:188df1a0-a81d-4b9c-9f77-110f3b2aff6c

.