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You searched for +publisher:"Dalhousie University" +contributor:("Dr. Jian Wang"). Showing records 1 – 2 of 2 total matches.

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Dalhousie University

1. Almuklass, Awad M. The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs.

Degree: MS, Department of Physiology & Biophysics, 2012, Dalhousie University

Noise exposure is one of the most common causes for acquired sensorineural hearing loss (SNHL). Recent studies have demonstrated that low-level noise exposure can kill spiral ganglion neurons (SGNs) without causing permanent hearing threshold shift. The present study further investigated the dynamic changes of ribbons in the cochlea of guinea pigs and the impact of the noise-induced synaptic damage and the loss of SGNs on the temporal processing of the cochlea in both mice and guinea pigs. Unlike what was reported in mice, the initial loss of ribbon in guinea pigs (>60% at high frequency region) largely recovered within one month after the noise, which was consistent with the functional recovery in auditory sensitivity and cochlear response amplitude. However, temporal processing in guinea pigs and mice remained deteriorated long after the hearing threshold was recovered. Advisors/Committee Members: Dr Richard E Brown (external-examiner), Dr Elizabeth A Cowley (graduate-coordinator), Dr Steven Barnes and Dr Steven Aiken (thesis-reader), Dr Jian Wang (thesis-supervisor), Not Applicable (ethics-approval), Not Applicable (manuscripts), Not Applicable (copyright-release).

Subjects/Keywords: Subject Not Available

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Almuklass, A. M. (2012). The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs. (Masters Thesis). Dalhousie University. Retrieved from http://hdl.handle.net/10222/14823

Chicago Manual of Style (16th Edition):

Almuklass, Awad M. “The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs.” 2012. Masters Thesis, Dalhousie University. Accessed March 21, 2019. http://hdl.handle.net/10222/14823.

MLA Handbook (7th Edition):

Almuklass, Awad M. “The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs.” 2012. Web. 21 Mar 2019.

Vancouver:

Almuklass AM. The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs. [Internet] [Masters thesis]. Dalhousie University; 2012. [cited 2019 Mar 21]. Available from: http://hdl.handle.net/10222/14823.

Council of Science Editors:

Almuklass AM. The Functional and Morphological Changes by Noise without Causing Hearing Loss: A Comparison between Mice and Guinea Pigs. [Masters Thesis]. Dalhousie University; 2012. Available from: http://hdl.handle.net/10222/14823


Dalhousie University

2. MacEacheron, Allison. PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION.

Degree: MS, School of Human Communication Disorders, 2015, Dalhousie University

The Envelope Following Response (EFR) has been under investigation as part of the ASSR evoked potential but it is unclear where exactly this periodicity envelope originates. The commonly accepted theory holds that the periodicity envelope is introduced due to cochlear interactions and non-linearities but this does not account for measurable EFR responses to resolved stimuli (i.e. stimuli that should not interact on the basilar membrane; Korczak et al. 2012). Laroche et al. (2013) therefore proposed that the EFR to resolved stimuli arises centrally. To investigate this theory, EFR were measured to stimuli of different modulation rates, component frequencies, and phase relationships in normal hearing individuals. When stimuli were unresolved, response amplitude was seen to increase with decreasing degree of resolution and decrease when the envelope was minimized in the stimulus via phase manipulation, supporting the accepted hypothesis. When stimuli were resolved, response amplitude decreased with increasing component frequency (suggesting that phase locking is required) and responses were unaffected by phase-based minimization of the stimulus envelope. This evidence supports the theory that EFR to resolved harmonics is introduced centrally for it suggests that temporal encoding of the stimulus components by auditory nerve fibers is required before an EFR can be reliably measured. We therefore conclude that the periodicity envelope measured in the EFR is introduced at different levels along the auditory system depending on the resolution of its components. Advisors/Committee Members: Dr. Manohar Bance (external-examiner), Dr. Joy Armson (graduate-coordinator), Dr. Jian Wang (thesis-reader), Dr. David Purcell (thesis-reader), Dr. Michael Kiefte (thesis-reader), Dr. Steven Aiken (thesis-supervisor), Received (ethics-approval), Not Applicable (manuscripts), Not Applicable (copyright-release).

Subjects/Keywords: Electrophysiology; Auditory Steady State Response; Audiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

MacEacheron, A. (2015). PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION. (Masters Thesis). Dalhousie University. Retrieved from http://hdl.handle.net/10222/56317

Chicago Manual of Style (16th Edition):

MacEacheron, Allison. “PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION.” 2015. Masters Thesis, Dalhousie University. Accessed March 21, 2019. http://hdl.handle.net/10222/56317.

MLA Handbook (7th Edition):

MacEacheron, Allison. “PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION.” 2015. Web. 21 Mar 2019.

Vancouver:

MacEacheron A. PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION. [Internet] [Masters thesis]. Dalhousie University; 2015. [cited 2019 Mar 21]. Available from: http://hdl.handle.net/10222/56317.

Council of Science Editors:

MacEacheron A. PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION. [Masters Thesis]. Dalhousie University; 2015. Available from: http://hdl.handle.net/10222/56317

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