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You searched for +publisher:"Cornell University" +contributor:("Siggia, Eric Dean"). Showing records 1 – 2 of 2 total matches.

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Cornell University

1. Ristroph, Leif. Dynamics, Control, And Stability Of Fruit Fly Flight .

Degree: 2011, Cornell University

The flight of insects is a beautiful example of an organism's complex interaction with its physical environment. Consider, for example, a fly's evasive dodge of an approaching swatter. The insect must orchestrate a cascade of events that starts with the visual system perceiving information that is then processed and transmitted through neural circuits. Next, muscle actions are triggered that induce changes to the insect's wing motions, and these motions interact with fluid flows to generate aerodynamic forces. Though not as obvious to appreciate, simply flying straight and keeping upright require similarly complex events in order to overcome unexpected disturbances and suppress intrinsic instabilities. Here, I present recent progress in dissecting the many layers that comprise maneuvering and stabilization in the flight of the fruit fly, D. melanogaster. My emphasis is on aspects of flight at the interface of biology and physics, and I seek to understand how physical effects both constrain and simplify biological strategies. This body of work roughly divides into three thrusts: the development of experimental and modeling methods, studies of actuation and control of maneuvering flight, and studies of control during flight stabilization. In Chapter 2, I discuss the experimental techniques we have developed for gathering many three-dimensional high-speed videos of insect flight. In addition, I outline our approach for automated extraction of body and wing motions from such videos. In Chapter 3, I show how experimental observations can be combined with aero- dynamic models to reveal that fruit flies use paddling motions to drive forward flight. In Chapter 4, I review our work on turning maneuvers with an emphasis on how the wing motions themselves arise through an actuation mechanism. In Chapter 5, I outline a set of experimental and modeling techniques for understanding how insects recover from in-flight perturbations to their heading. In Chapter 6, I use a similar approach to analyze the intrinsic instability of body pitch and predict the reaction time needed to stabilize flight. In Chapter 7, I include work on the hydrodynamic interactions between flapping bodies in a fluid flow. Advisors/Committee Members: Ralph, Daniel C (committeeMember), Siggia, Eric Dean (committeeMember).

Subjects/Keywords: Insect flight; Aerodynamics; Stability and control

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Ristroph, L. (2011). Dynamics, Control, And Stability Of Fruit Fly Flight . (Thesis). Cornell University. Retrieved from http://hdl.handle.net/1813/29392

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Ristroph, Leif. “Dynamics, Control, And Stability Of Fruit Fly Flight .” 2011. Thesis, Cornell University. Accessed March 24, 2019. http://hdl.handle.net/1813/29392.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Ristroph, Leif. “Dynamics, Control, And Stability Of Fruit Fly Flight .” 2011. Web. 24 Mar 2019.

Vancouver:

Ristroph L. Dynamics, Control, And Stability Of Fruit Fly Flight . [Internet] [Thesis]. Cornell University; 2011. [cited 2019 Mar 24]. Available from: http://hdl.handle.net/1813/29392.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ristroph L. Dynamics, Control, And Stability Of Fruit Fly Flight . [Thesis]. Cornell University; 2011. Available from: http://hdl.handle.net/1813/29392

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Segota, Igor. Physical Aspects Of Chemotaxis And Proliferation Of Dictyostelium Discoideum Amoeba .

Degree: 2014, Cornell University

In this dissertation, we explore two aspects of Dictyostelium discoideum life cycle, chemotaxis and proliferation. We use Shannon's information theory to study the physical limits of chemotaxis due to the stochastic process of ligands binding and unbinding to cell receptors (receptor noise). Using microfluidic experiments, we show that cells acquire much more information than the contemporary application of this theory allows. Next, we investigate how cells modify their extracellular environment by secreting enzymes that degrade chemoattractants and show that simple first order degradation leads to the significant improvement of the receptor signal-to-noise ratio of chemical gradients. Finally, we investigate the seemingly solitary vegetative phase of the same cells and find that they synchronize their growth after transferring from suspension culture to substrate. We show that this synchronization can be suppressed using microfluidic flow experiments, indicating that the synchronization is a collective behavior mediated by a diffusible molecule. Advisors/Committee Members: Elser, Veit (committeeMember), Gruner, Sol Michael (committeeMember), Siggia, Eric Dean (committeeMember).

Subjects/Keywords: biophysics; information theory; chemotaxis

…preparation of chemotacting media and helpful suggestions, Elijah Bogart (Cornell University… …x28;Cornell University), Kevin Tharratt (Cornell University) for fruitful… …University), Eric Siggia (Rockefeller University/Cornell University) and Nives… …Institute Goettingen, Germany/Cornell University) for generous advice and equipment… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Segota, I. (2014). Physical Aspects Of Chemotaxis And Proliferation Of Dictyostelium Discoideum Amoeba . (Thesis). Cornell University. Retrieved from http://hdl.handle.net/1813/38991

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Segota, Igor. “Physical Aspects Of Chemotaxis And Proliferation Of Dictyostelium Discoideum Amoeba .” 2014. Thesis, Cornell University. Accessed March 24, 2019. http://hdl.handle.net/1813/38991.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Segota, Igor. “Physical Aspects Of Chemotaxis And Proliferation Of Dictyostelium Discoideum Amoeba .” 2014. Web. 24 Mar 2019.

Vancouver:

Segota I. Physical Aspects Of Chemotaxis And Proliferation Of Dictyostelium Discoideum Amoeba . [Internet] [Thesis]. Cornell University; 2014. [cited 2019 Mar 24]. Available from: http://hdl.handle.net/1813/38991.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Segota I. Physical Aspects Of Chemotaxis And Proliferation Of Dictyostelium Discoideum Amoeba . [Thesis]. Cornell University; 2014. Available from: http://hdl.handle.net/1813/38991

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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