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Colorado State University
1.
Limhapirom, Patchara.
Assessment of the introduction and spread of highly pathogenic avian influenza (H5N1) in Thailand: application of market chain analysis of poultry and the use of community-based disease prevention strategies.
Degree: MS(M.S.), Clinical Sciences, 2013, Colorado State University
URL: http://hdl.handle.net/10217/80263
► An analysis of the market chain and trade pathway for the small poultry production system was conducted in Ban Klang Subdistrict, Nakhon Phanom Mueang District,…
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▼ An analysis of the market chain and trade pathway for the small poultry production system was conducted in Ban Klang Subdistrict, Nakhon Phanom Mueang District, Nakhon Phanom Province, Thailand. The aim of the study was to determine the risk of highly pathogenic avian influenza (HPAI/H5N1) introduction and transmission along the poultry market chain, and then apply a community-based approach to prevent the introduction and spread of H5N1 along the identified chain. The focus was on the layer market chain because an outbreak of HPAI was reported 24 July 2006 at a layer farm in Banklang Subdistrict. Six human patients were suspected to be infected with Avian Influenza virus (AI), but no cases were reported after the surveillance was initiated (MOPH 2006). A cross-sectional analysis method was used to identify the poultry market chain and assess the risk of introduction and transmission of AI along that chain. For linking actors along the poultry market chain, the snowball sampling method was used. The data were collected by using a structured questionnaire and applying focus discussion group activity (FDG), which is part of the community-based approach, to the high-risk actors in the poultry market chain. Participants' level of knowledge, attitude and practice behaviors (KAP) regarding AI was assessed, as well as the risk of AI in the poultry market chain. From three layer product pathways—eggs, spent hens and disposal of layer manure—the findings demonstrated that the spent hens and disposal of layer manure are higher-risk pathways for the introduction and transmission of HPAI than the egg products pathway. The farmers (producers) have the highest risk of contracting the AI virus because of their constant proximity to poultry, while traders have the highest risk of transmitting the AI virus along the layer market chain as their business requires moving from farm to farm. A survey of KAP regarding AI showed that the majority of farmers had a high level of knowledge and positive practice behaviors. This was compared to traders where more than half had only moderate to low knowledge, and positive practice behaviors. The majority of farmers and traders, however, had a positive attitude toward policies of prevention and control of HPAI through a surveillance system in their community. The FDG demonstrated that other actors expected an efficient HPAI prevention system at the producer level. The results of this study showed that community involvement in an HPAI surveillance system should be considered for all related actors in the poultry market chain. In order to be effective, the policies should be followed and periodically monitored for compliance.
Advisors/Committee Members: Salman, Mo (advisor), Keefe, Thomas (committee member), Wongsathapornchai, Kachen (committee member).
Subjects/Keywords: analysis; poultry market chain; KAP; highly pathogenic avian influenza (HPAI); community-based
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APA (6th Edition):
Limhapirom, P. (2013). Assessment of the introduction and spread of highly pathogenic avian influenza (H5N1) in Thailand: application of market chain analysis of poultry and the use of community-based disease prevention strategies. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/80263
Chicago Manual of Style (16th Edition):
Limhapirom, Patchara. “Assessment of the introduction and spread of highly pathogenic avian influenza (H5N1) in Thailand: application of market chain analysis of poultry and the use of community-based disease prevention strategies.” 2013. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/80263.
MLA Handbook (7th Edition):
Limhapirom, Patchara. “Assessment of the introduction and spread of highly pathogenic avian influenza (H5N1) in Thailand: application of market chain analysis of poultry and the use of community-based disease prevention strategies.” 2013. Web. 05 Mar 2021.
Vancouver:
Limhapirom P. Assessment of the introduction and spread of highly pathogenic avian influenza (H5N1) in Thailand: application of market chain analysis of poultry and the use of community-based disease prevention strategies. [Internet] [Masters thesis]. Colorado State University; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/80263.
Council of Science Editors:
Limhapirom P. Assessment of the introduction and spread of highly pathogenic avian influenza (H5N1) in Thailand: application of market chain analysis of poultry and the use of community-based disease prevention strategies. [Masters Thesis]. Colorado State University; 2013. Available from: http://hdl.handle.net/10217/80263

Colorado State University
2.
Tangtrongsup, Sahatchai.
Molecular epidemiology of Giardia and Cryptosporidium in dogs and cats in Chiang Mai, Thailand.
Degree: PhD, Clinical Sciences, 2013, Colorado State University
URL: http://hdl.handle.net/10217/80196
► Giardia duodenalis and Cryptosporidium spp. are the common causes of diarrhea in humans and animals, including domestic and wildlife, throughout the world. The species complex…
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▼ Giardia duodenalis and Cryptosporidium spp. are the common causes of diarrhea in humans and animals, including domestic and wildlife, throughout the world. The species complex G. duodenalis and the genus Cryptosporidium consist of host-adapted and zoonotic genotypes/species. Companion animals, especially dogs and cats, can be infected by the host-adapted as well as the zoonotic genotype/species of these organisms. Therefore, these animals have been questioned regarding their potential to serve as reservoirs for human transmission. In this dissertation, an epidemiological study of Giardia and Cryptosporidium as well as the molecular characterization of these organisms in dogs and cats in Chiang Mai, Thailand was completed. A greater understanding of the prevalence and risk factors associated with Giardia and Cryptosporidium infection can aid veterinarians in the control and prevention of these important diseases. Furthermore, the potential for zoonotic transmission will be reduced. In Chapter 1, Giardia and Cryptosporidium and its epidemiology in dogs and cats are reviewed as well as an update on the situation regarding giardiasis and cryptosporidiosis in Thailand. In Chapter 2, a preliminary study to determine the prevalence of Giardia and Cryptosporidium infection in dogs and cats in Chiang Mai, Thailand is described. Fecal samples were collected for two months (July and August, 2008). The genotype/species of these two organisms were determined as well as the risks associated with infection such as age, sex, diarrhea status, housing type and the presence of co-infection of Cryptosporidium (for Giardia infection) or the presence of Giardia in the case of Cryptosporidium infection. It was shown that Giardia and Cryptosporidium infections were common in dogs in Chiang Mai and that dogs could be a potential reservoir for zoonotic transmission to humans. In Chapter 3, the larger cross-sectional study is described. Samples were collected a year later from August 2009 to February 2010. The objectives were to determine the effect of seasonality (wet months or rainy vs. dry months or winter), to determine the potential risk factors associated with Giardia and Cryptosporidium infections, as well as to determine the genotype/species of these organisms. The results suggested that Giardia infection in dogs was prevalent in the rainy season, whereas seasonality was not significantly associated with Cryptosporidium infection. Young dogs, dogs living in crowded settings, dogs having diarrhea or chronic diarrhea, and dogs shedding Cryptosporidium oocysts had a high risk for Giardia infection. Risk factors associated with Cryptosporidium infection in dogs were age less than one year and dogs having diarrhea. Giardia duodenalis assemblage A and C. parvum were identified in this study; however, the potential role in zoonotic transmission could not be determined. Chapter 4 presents a brief report on the comparison of sugar and sedimentation concentration techniques prior to immunofluorescent assay to detect Giardia cysts and…
Advisors/Committee Members: Salman, Mo (advisor), Lappin, Michael (advisor), Ballweber, Lora (committee member), Reif, John (committee member).
Subjects/Keywords: cryptosporidium; molecular characterization; giardia; cats; dogs; Thailand
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APA (6th Edition):
Tangtrongsup, S. (2013). Molecular epidemiology of Giardia and Cryptosporidium in dogs and cats in Chiang Mai, Thailand. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/80196
Chicago Manual of Style (16th Edition):
Tangtrongsup, Sahatchai. “Molecular epidemiology of Giardia and Cryptosporidium in dogs and cats in Chiang Mai, Thailand.” 2013. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/80196.
MLA Handbook (7th Edition):
Tangtrongsup, Sahatchai. “Molecular epidemiology of Giardia and Cryptosporidium in dogs and cats in Chiang Mai, Thailand.” 2013. Web. 05 Mar 2021.
Vancouver:
Tangtrongsup S. Molecular epidemiology of Giardia and Cryptosporidium in dogs and cats in Chiang Mai, Thailand. [Internet] [Doctoral dissertation]. Colorado State University; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/80196.
Council of Science Editors:
Tangtrongsup S. Molecular epidemiology of Giardia and Cryptosporidium in dogs and cats in Chiang Mai, Thailand. [Doctoral Dissertation]. Colorado State University; 2013. Available from: http://hdl.handle.net/10217/80196

Colorado State University
3.
Mann, Heather.
Bovine tuberculosis slaughter surveillance in the United States: assessment of its trace-back function 2001-2010.
Degree: MS(M.S.), Clinical Sciences, 2012, Colorado State University
URL: http://hdl.handle.net/10217/67314
► The detection of gross bovine tuberculosis (bovine TB) lesions in cattle at slaughter and the successful trace-back to the herd of origin is critical to…
(more)
▼ The detection of gross bovine tuberculosis (bovine TB) lesions in cattle at slaughter and the successful trace-back to the herd of origin is critical to the detection of infected herds and for the progress of the national bovine TB eradication program in the United States (U.S.). A national animal identification system to identify and trace individual animals is currently under development in the U.S.; however, it is not yet fully implemented. In order to quantify the impact slaughter surveillance and traceability of bovine TB infected cattle has on the eradication of bovine TB from the cattle population in the U.S., this study was conducted with the aim to determine the ability of the current bovine TB slaughter surveillance system to trace infected cattle back to the herd of origin. Data obtained for the period 2001-2010, in which 386 bovine lesions were confirmed as bovine TB in the U.S., were used for this study. The specific objectives for this study were 1) to review and document the available literature related to the history of bovine TB control in the U.S., focusing primarily on the current method of disease detection (slaughter surveillance) and the impediments to eradication in the U.S., 2) to quantify the number of successful trace-backs of bovine TB infected animals to their herd of origin during 2001-2010 3) to quantify the number of trace-backs that found at least one bovine TB infected ("affected") herd, and 4) determine if selected factors were associated with the probability of successfully tracing infected animals and finding infected herds. The results of this study indicates that the odds of successful trace-backs are 7.06 times greater for cattle with official identification than without official identification (OR 95% CI: 1.66, 29.93, p-value =0.008). Additionally, the odds of successful trace-back are 15.47 times greater for adult cattle compared to fed cattle (OR 95% CI: 4.47, 53.48, p-value<0.001). Thus, application of official ID on all classes of cattle would increase the probability of successfully tracing bovine TB cases back to a herd of origin; however, under the current system it will not ensure a complete success in tracing bovine TB infected cattle to the herd of origin. While adult cattle are currently more likely to be traced back than fed cattle, it is worth noting that the effort and time required to find the herd of origin for both adult and fed bovine TB cases can be substantial and is highly variable. The results of this study provide an important tool to aid U.S. officials in their decision making with respect to the evaluation and implementation of strategies for the national bovine TB control and eradication program.
Advisors/Committee Members: Olea-Popelka, Francisco (advisor), Orloski, Kathleen (committee member), Salman, Mo (committee member), Basaraba, Randall (committee member).
Subjects/Keywords: animal sciences; epidemiology; trace-back; United States; bovine tuberculosis; cattle
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mann, H. (2012). Bovine tuberculosis slaughter surveillance in the United States: assessment of its trace-back function 2001-2010. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/67314
Chicago Manual of Style (16th Edition):
Mann, Heather. “Bovine tuberculosis slaughter surveillance in the United States: assessment of its trace-back function 2001-2010.” 2012. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/67314.
MLA Handbook (7th Edition):
Mann, Heather. “Bovine tuberculosis slaughter surveillance in the United States: assessment of its trace-back function 2001-2010.” 2012. Web. 05 Mar 2021.
Vancouver:
Mann H. Bovine tuberculosis slaughter surveillance in the United States: assessment of its trace-back function 2001-2010. [Internet] [Masters thesis]. Colorado State University; 2012. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/67314.
Council of Science Editors:
Mann H. Bovine tuberculosis slaughter surveillance in the United States: assessment of its trace-back function 2001-2010. [Masters Thesis]. Colorado State University; 2012. Available from: http://hdl.handle.net/10217/67314

Colorado State University
4.
Premashthira, Sith.
Uses of quantitative spatial analysis and epidemiological simulation modeling for assessing control strategies for foot-and-mouth disease.
Degree: PhD, Clinical Sciences, 2012, Colorado State University
URL: http://hdl.handle.net/10217/67624
► This study addressed issues related to a hypothetical outbreak of foot-and-mouth disease (FMD) comparing a limited control measure to additional control strategies where there were…
(more)
▼ This study addressed issues related to a hypothetical outbreak of foot-and-mouth disease (FMD) comparing a limited control measure to additional control strategies where there were limited control strategies within FMD virus free area. The central United States was selected as the study area, and the spatial pattern of FMD and its determinants were observed after FMD was introduced into the center of the area. The research reported the magnitude of the outbreaks in different scenarios having different control strategies. The first four chapters in this dissertation cover the sequence of research methods, and the final chapter includes the results and discussion. Chapter 1 reviews aspects of epidemiology of FMD, epidemiological simulation modeling, and spatial analysis with the focus on FMD in terms of disease control. The review stimulated some ideas to generate parameters for the FMD simulation modeling that was done in Chapter 2. Chapter 2 explains the process for generating parameters for a hypothetical outbreak of FMD in the central Unites States. The process included gathering location study premises in the study area from many sources and a simulator. The disease stage and transmission parameters of FMD were estimated from reviews and statistical analyses of data distribution, adjusted for study premises size. The sensitivity analysis of important parameters was analyzed by comparing disease spread for various values of the input parameters. Chapter 3 examines the practical plans in place for FMD control and eradication. The baseline scenario was set up from the base parameters from Chapter 2 and included some limited control strategies. The additional five strategies included additional intensive disease control measures such as restricted animal movement, additional animal destruction, or ring vaccination. The baseline and extra five scenarios were simulated in a simulator and their magnitude was observed, including epidemic duration and estimated number of destroyed and/or vaccinated animals. Chapter 4 identifies the simulated outbreak region and its spatial determinants in the baseline scenario. The density estimation of affected areas was determined and illustrated by maps. Additional quantitative spatial methods such as spatial continuity, autocorrelation, and autoregressive model were analyzed to explain spatial trends and factors related to the affected areas. Chapter 5 concludes the important findings of this research. The overall conclusion summarizes the results from the previous chapters. A hypothetical outbreak of FMD in a large study area such as the one in this research should identify the premises of livestock as the unit of interest. The spread of FMD in the area may be primarily caused by indirect contact rather than direct contact and airborne transmission. The change of parameters in the indirect contact rates was sensitive to the outcome of the simulation. All additional disease control strategies were better than the baseline scenario in terms of reducing the magnitude of the outbreak,…
Advisors/Committee Members: Salman, Mo (advisor), Hill, Ashley (committee member), Reich, Robin (committee member), Wagner, Bruce (committee member).
Subjects/Keywords: control strategies; quantitative spatial analysis; foot-and-mouth disease; epidemiological simulation modeling
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Premashthira, S. (2012). Uses of quantitative spatial analysis and epidemiological simulation modeling for assessing control strategies for foot-and-mouth disease. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/67624
Chicago Manual of Style (16th Edition):
Premashthira, Sith. “Uses of quantitative spatial analysis and epidemiological simulation modeling for assessing control strategies for foot-and-mouth disease.” 2012. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/67624.
MLA Handbook (7th Edition):
Premashthira, Sith. “Uses of quantitative spatial analysis and epidemiological simulation modeling for assessing control strategies for foot-and-mouth disease.” 2012. Web. 05 Mar 2021.
Vancouver:
Premashthira S. Uses of quantitative spatial analysis and epidemiological simulation modeling for assessing control strategies for foot-and-mouth disease. [Internet] [Doctoral dissertation]. Colorado State University; 2012. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/67624.
Council of Science Editors:
Premashthira S. Uses of quantitative spatial analysis and epidemiological simulation modeling for assessing control strategies for foot-and-mouth disease. [Doctoral Dissertation]. Colorado State University; 2012. Available from: http://hdl.handle.net/10217/67624

Colorado State University
5.
Evans, Rebecca I.
One health in the U.S. military: a review of existing systems and recommendations for the future.
Degree: PhD, Clinical Sciences, 2014, Colorado State University
URL: http://hdl.handle.net/10217/83736
► Background: The merging of the former U.S. Army Veterinary Command (VETCOM) with the former U.S. Army Center for Health Promotion and Preventive Medicine (USACHPPM) into…
(more)
▼ Background: The merging of the former U.S. Army Veterinary Command (VETCOM) with the former U.S. Army Center for Health Promotion and Preventive Medicine (USACHPPM) into the U.S. Army Public Health Command (USAPHC) in 2011 created an opportunity for the military to fully embrace the One Health concept. That same year, the USAPHC began work on a Zoonotic Disease Report (ZDR) aimed at supporting critical zoonotic disease risk assessments by combining zoonotic disease data from human, entomological, laboratory, and animal data sources. The purpose of this dissertation is to facilitate the creation of a military Zoonotic Disease Surveillance program that combines disease data from both military human and animal sources. Methods: Five of the most commonly used human military medical data systems were systematically reviewed using a standardized template based on Centers for Disease Control and Preventive Medicine (CDC) guidelines. The systems were then compared to each other in order to recommend the one(s) best suited for use in the USAPHC ZDR. The first stage of the comparison focused on each system's ability to meet the specific goals and objectives of the ZDR, whereas the second stage applied capture-recapture methodology to data system queries in order to evaluate each system's data quality (completeness). A pilot study was conducted using Lyme borreliosis to investigate the utility of military pet dogs as sentinel surveillance for zoonotic disease in military populations. Canine data came from 3996 surveys collected from 15 military veterinary facilities from 1 November 2012 through 31 October 2013. Surveys simultaneously collected Borrelia burgdorferi (Bb) seroprevalence and canine risk factor data for each participating pet dog. Human data were obtained by querying the Defense Medical Surveillance System for the same 15 military locations and the same time period. The correlation of military pet dog Bb seroprevalence and military human Lyme disease (borreliosis) data was estimated using the Spearman Rank Correlation. The difference between military pet dog data and civilian pet dog data was examined through the use of the chi-squared test for proportions. Multivariable logistic regression was then used to investigate the potential for identified risk factors to impact the observed association. Results: The comparison of human military medical data systems found the Military Health System Management Analysis and Reporting Tool (M2) data system most completely met the specific goals and objects of the ZDR. In addition, completeness calculation showed the M2 data source to be the most complete source of human data; 55% of total captured cases coming from the M2 system alone. The pilot study found a strong positive correlation between military human borreliosis data and military pet dog Bb seroprevalence data by location (rs = 0.821). The study showed reassuring similarities in pet dog seroprevalence by location for the majority of sites, but also showed meaningful differences between two…
Advisors/Committee Members: Salman, Mo (advisor), Lappin, Michael (committee member), Hayne, Stephen (committee member), Peel, Jennifer (committee member).
Subjects/Keywords: zoonotic disease; capture-recapture; surveillance
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Evans, R. I. (2014). One health in the U.S. military: a review of existing systems and recommendations for the future. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/83736
Chicago Manual of Style (16th Edition):
Evans, Rebecca I. “One health in the U.S. military: a review of existing systems and recommendations for the future.” 2014. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/83736.
MLA Handbook (7th Edition):
Evans, Rebecca I. “One health in the U.S. military: a review of existing systems and recommendations for the future.” 2014. Web. 05 Mar 2021.
Vancouver:
Evans RI. One health in the U.S. military: a review of existing systems and recommendations for the future. [Internet] [Doctoral dissertation]. Colorado State University; 2014. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/83736.
Council of Science Editors:
Evans RI. One health in the U.S. military: a review of existing systems and recommendations for the future. [Doctoral Dissertation]. Colorado State University; 2014. Available from: http://hdl.handle.net/10217/83736

Colorado State University
6.
Zurita Urrea, Paulina.
Derivatization protocol for mycolic acids detection using liquid chromatography/mass spectrometry, A.
Degree: MS(M.S.), Microbiology, Immunology, and Pathology, 2012, Colorado State University
URL: http://hdl.handle.net/10217/75304
► New tools for the diagnosis and control of Tuberculosis are major challenges. In this context the use of biomarkers can be applied for detecting characteristic…
(more)
▼ New tools for the diagnosis and control of Tuberculosis are major challenges. In this context the use of biomarkers can be applied for detecting characteristic signatures from the tuberculosis-infected host and the pathogen. Mycolic acids are considered as a hallmark of the Mycobacterium genus being abundant in the mycobacterial cell wall. In this study a derivatization protocol was tested to enhance the detection of mycolic acid after the attachment of a quaternary amine and analysis of the derivatized products in the positive ionization mode with liquid chromatography/mass spectrometry. Three groups were considered i) mycolic acid standard ii) human urine spiked with mycolic acid standard, and iii) human serum spiked with mycolic acid standard. Each group included the analysis of a set of non-derivatized mycolic acids in positive and negative ionization mode, and derivatized mycolic acids in positive mode. The derivatization process applied to the mycolic acid standard and to the urine samples spiked with mycolic did not improve the ion volume value compared to the respective non-derivatized samples. Serum samples, however, showed a significant enhancement in the ion volume of the different mycolic acids analyzed compared to the non-derivatized serum samples (α=0.05). The method detection limit for the three groups was also achieved. Urine and serum samples spiked with mycolic acids showed higher detection limits compared to the mycolic acid standard; this was expected due the lipid extraction protocol and the complex nature of these fluids. The derivatization protocol did not improve the method detection limit compared to the non-derivatized samples. The overall results make the derivatization protocol questionable to be applied routinely in biological samples. However, the results obtained after the derivatization of serum samples could point to the advantages of using a derivatization protocol to study possible interactions between mycolic acids and other molecules present in serum that could be impeding their detection.
Advisors/Committee Members: Belisle, John T. (advisor), Jones, Robert (committee member), Salman, Mo (committee member).
Subjects/Keywords: biomarker; derivatization; mass spectrometry; mycolic acids
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APA ·
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APA (6th Edition):
Zurita Urrea, P. (2012). Derivatization protocol for mycolic acids detection using liquid chromatography/mass spectrometry, A. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/75304
Chicago Manual of Style (16th Edition):
Zurita Urrea, Paulina. “Derivatization protocol for mycolic acids detection using liquid chromatography/mass spectrometry, A.” 2012. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/75304.
MLA Handbook (7th Edition):
Zurita Urrea, Paulina. “Derivatization protocol for mycolic acids detection using liquid chromatography/mass spectrometry, A.” 2012. Web. 05 Mar 2021.
Vancouver:
Zurita Urrea P. Derivatization protocol for mycolic acids detection using liquid chromatography/mass spectrometry, A. [Internet] [Masters thesis]. Colorado State University; 2012. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/75304.
Council of Science Editors:
Zurita Urrea P. Derivatization protocol for mycolic acids detection using liquid chromatography/mass spectrometry, A. [Masters Thesis]. Colorado State University; 2012. Available from: http://hdl.handle.net/10217/75304

Colorado State University
7.
Ku, Kyung-nyer.
Equine body weight estimation using three-dimensional images.
Degree: MS(M.S.), Clinical Sciences, 2015, Colorado State University
URL: http://hdl.handle.net/10217/167238
► Accurately estimating the body weight (BW) of a horse is important in order to make appropriate management and treatment decisions. Most field equine veterinarians and…
(more)
▼ Accurately estimating the body weight (BW) of a horse is important in order to make appropriate management and treatment decisions. Most field equine veterinarians and experienced equine people, however, visually estimate BW because large animal scales are impractical for field use due to the weight (>80 kg), size (length >200 cm), and cost (>$1,000). There are some alternative BW estimation methods such as a weight tape or BW estimation using a combination of heart girth and body length measurements. These methods, however, have 5 - 15% or even higher margin of error. According to human studies, there is a high correlation between BW and body volume (BV). Correlation coefficient (R) between these two variables is 0.996-0.998. Our study was designed to develop methods to estimate the BW of horses by using 3D image based BV measurement. 3D imaging technology allows easy and accurate measurement of diverse indices of an object, including the volume. Recent development of Structure-light 3D scanning technology allows 3D scanning of an object as large as 3 by 3 square meter in a short time. In this study, 3D images of 22 and 11 horses were obtained by using 3D scanning (3DScan) and photogrammetry (2Dto3D), respectively. BV and trunk volume (TV) of the horses were measured from the obtained 3D images. Measurements of BW using five conventional methods (visual estimation, 2 weight tapes (Purina, Shell), estimated BW by using heart girth and body length (Carroll’s formula), and a large animal scale) were also conducted, and the data of body condition score (BCS), sex, coat color, and coat type of the horses were collected. Linear regression models to estimate the BW of the horse based on the volume and other independent variables were developed using regression model stepwise selection procedures (P<0.05). Variables selected in 3DScan method were BV, sex, and coat type, and, in 2Dto3D method, BV (TV) was selected. The coefficient of determination of the developed regression models were 0.95 and 0.78-0.82, respectively, and the average percent errors of the predicted BW compared to the true BW of horses were 2.07 % and 2.67 %, respectively. The accuracy of the 3DScan method was significantly more accurate than WT, Carroll’s formual, and VE (P<0.05). 3D image based BW measurement method had higher accuracy and convenience compared to conventional alternative BW measuring methods. Accurate and easy determination of BW using 3D images will allow for regular BW measurement in the field and allow optimal equine health management by equine stakeholders and practitioners. The 3D images obtained in this study were highly detailed. Further graphical analysis of the obtained 3D images will make it possible to use this technology on automatic evaluation of body condition score, equine conformation evaluation, breed registration, and the study of pharmacokinetics and dynamics of newly developed drugs. This research findings may also have utility for application to wild or zoo animals such as the elephant, rhinoceros, or even the…
Advisors/Committee Members: Traub-Dargatz, Josie L. (advisor), Salman, Mo (advisor), Alciatore, David (committee member), Hess, Tanja (committee member).
Subjects/Keywords: horse; three-dimensional; image; body weight
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ku, K. (2015). Equine body weight estimation using three-dimensional images. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/167238
Chicago Manual of Style (16th Edition):
Ku, Kyung-nyer. “Equine body weight estimation using three-dimensional images.” 2015. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/167238.
MLA Handbook (7th Edition):
Ku, Kyung-nyer. “Equine body weight estimation using three-dimensional images.” 2015. Web. 05 Mar 2021.
Vancouver:
Ku K. Equine body weight estimation using three-dimensional images. [Internet] [Masters thesis]. Colorado State University; 2015. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/167238.
Council of Science Editors:
Ku K. Equine body weight estimation using three-dimensional images. [Masters Thesis]. Colorado State University; 2015. Available from: http://hdl.handle.net/10217/167238

Colorado State University
8.
Wiedenheft, Alyson M.
Use of on-line continuing education modules to improve awareness of African horse sickness among U.S. equine veterinarians, The.
Degree: MS(M.S.), Clinical Sciences, 2011, Colorado State University
URL: http://hdl.handle.net/10217/52133
► U.S. equine veterinary practitioners will likely be responsible for the detection and reporting of a foreign animal disease (FAD) incursion, such as African horse sickness…
(more)
▼ U.S. equine veterinary practitioners will likely be responsible for the detection and reporting of a foreign animal disease (FAD) incursion, such as African horse sickness (AHS), into the U.S. On-line continuing education is one method of increasing awareness about FADs among equine veterinarians by providing a consistent message that can be conveniently accessed by most veterinarians. Two major types of on-line continuing education include webinar and text formatted modules. An on-line educational assessment study for equine veterinarians was developed to determine baseline knowledge of AHS as well as the effectiveness of webinar versus text formatted education modules. The results from this study imply that the participants were not initially prepared to recognize and report a suspect case of AHS. Additionally, the webinar and text formatted modules were equally effective in educating the equine veterinarians about AHS. The low voluntary participation rate in the study implies that on-line continuing education is not currently the best method for preparing equine veterinarians in the U.S. for an FAD outbreak. If equine veterinarians become more willing to participate in on-line education based on the new requirements for accreditation, or if incentives/penalties are used to promote on-line continuing education participation, this continuing education method may become more accepted by U.S. equine veterinarians in the future.
Advisors/Committee Members: Traub-Dargatz, Josie (advisor), Salman, Mo (advisor), Gillette, Shana (committee member), O'Keefe, Garrett (committee member).
Subjects/Keywords: continuing education; equine; foreign animal disease; on-line learning; veterinary; African horse sickness
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MLA ·
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APA (6th Edition):
Wiedenheft, A. M. (2011). Use of on-line continuing education modules to improve awareness of African horse sickness among U.S. equine veterinarians, The. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/52133
Chicago Manual of Style (16th Edition):
Wiedenheft, Alyson M. “Use of on-line continuing education modules to improve awareness of African horse sickness among U.S. equine veterinarians, The.” 2011. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/52133.
MLA Handbook (7th Edition):
Wiedenheft, Alyson M. “Use of on-line continuing education modules to improve awareness of African horse sickness among U.S. equine veterinarians, The.” 2011. Web. 05 Mar 2021.
Vancouver:
Wiedenheft AM. Use of on-line continuing education modules to improve awareness of African horse sickness among U.S. equine veterinarians, The. [Internet] [Masters thesis]. Colorado State University; 2011. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/52133.
Council of Science Editors:
Wiedenheft AM. Use of on-line continuing education modules to improve awareness of African horse sickness among U.S. equine veterinarians, The. [Masters Thesis]. Colorado State University; 2011. Available from: http://hdl.handle.net/10217/52133

Colorado State University
9.
Herman, Julia Anne.
Genetic natural resistance to brucellosis in Yellowstone National Park bison (Bison bison): a preliminary assessment.
Degree: MS(M.S.), Clinical Sciences, 2013, Colorado State University
URL: http://hdl.handle.net/10217/79061
► As a nationally recognized symbol of perseverance and survival, the American bison (Bison bison) continues to be the focus of many conservation efforts. This is…
(more)
▼ As a nationally recognized symbol of perseverance and survival, the American bison (Bison bison) continues to be the focus of many conservation efforts. This is particularly true in Yellowstone National Park (YNP) where genetic diversity and population dynamics are threatened by the presence of Brucella abortus infection, the causative agent of brucellosis. To further complicate management efforts, the potential for transmission of B. abortus to livestock surrounding the park could have effects on human and animal health in addition to negative economic impacts. Genetic natural resistance to infectious diseases such as brucellosis has been examined in bison and other species. Consideration of using genetic natural resistance as a management tool within YNP relies on its applicability to the population and effectiveness in identifying susceptible or resistant animals. The aim of this study was to further investigate genetic natural resistance to brucellosis in bison using the prion protein gene (PRNP). This could provide a genetic management tool for future populations by identifying resistant and susceptible genotypes to brucellosis that governing agencies could screen when selecting animals for removal. Animals used in this study were part of the Bison Quarantine Feasibility Study (BQFS), which was conducted by
state and federal government agencies to explore alternative options for bison that leave the protection of the park's perimeters as part of the Interagency Bison Management Plan (IBMP). After completing the study, the bison involved will be released into areas of their historic range and managed as a conservation herd. In addition to investigating genetic natural resistance, other genetic aspects were analyzed in this quarantine herd. We evaluated genetic diversity at 42 microsatellite loci representing each of the nuclear chromosomes in the bison genome. These markers allowed us to determine parentage which helped quantify the genetic diversity contained in the conservation herd. It was also important to understand the genetic diversity of the herd and to determine if any genetic characteristics such as cattle DNA introgression or low genetic diversity may threaten the protected status of this herd. Previously developed mitochondrial and nuclear DNA microsatellite markers were applied to determine if any introgression of domestic cattle DNA is presen. PRNP examination provided conflicting results from previous bison PRNP studies, justifying further research into the importance of PRNP in genetic natural resistance. As a conservation herd, this group of bison demonstrates high retention of unique YNP genetic diversity, high percentage of adult animals contributing offspring, and no evidence of cattle DNA introgression. This study explains support for using YNP bison as stocking animals for future satellite herds under the condition that BQFS protocol is followed. Results of these genetic analyses provide a thorough description of a quarantined herd of YNP bison destined for release to brucellosis-free public…
Advisors/Committee Members: Salman, Mo (advisor), Hill, Ashley (committee member), Huyvaert, Kathryn (committee member), Rhyan, Jack (committee member).
Subjects/Keywords: bison; brucellosis; genetic diversity; PRNP; satellite herd; Yellowstone National Park
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Herman, J. A. (2013). Genetic natural resistance to brucellosis in Yellowstone National Park bison (Bison bison): a preliminary assessment. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/79061
Chicago Manual of Style (16th Edition):
Herman, Julia Anne. “Genetic natural resistance to brucellosis in Yellowstone National Park bison (Bison bison): a preliminary assessment.” 2013. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/79061.
MLA Handbook (7th Edition):
Herman, Julia Anne. “Genetic natural resistance to brucellosis in Yellowstone National Park bison (Bison bison): a preliminary assessment.” 2013. Web. 05 Mar 2021.
Vancouver:
Herman JA. Genetic natural resistance to brucellosis in Yellowstone National Park bison (Bison bison): a preliminary assessment. [Internet] [Masters thesis]. Colorado State University; 2013. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/79061.
Council of Science Editors:
Herman JA. Genetic natural resistance to brucellosis in Yellowstone National Park bison (Bison bison): a preliminary assessment. [Masters Thesis]. Colorado State University; 2013. Available from: http://hdl.handle.net/10217/79061

Colorado State University
10.
Palomares Velosa, Jairo Enrique.
Acurracy assessment of four diagnostic tests for the detection of Giardia and Cryptosporidium in the absence of gold standard: a Bayesian approach.
Degree: MS(M.S.), Clinical Sciences, 2014, Colorado State University
URL: http://hdl.handle.net/10217/88550
► Giardia and Cryptosporidium are important parasites that cause gastrointestinal disease in numerous animal species including dogs and cats. The accurate diagnostic of this diseases is…
(more)
▼ Giardia and Cryptosporidium are important parasites that cause gastrointestinal disease in numerous animal species including dogs and cats. The accurate diagnostic of this diseases is cucial for the aplication of preventive measures and precise treatment. Estimation of test accuraccy is not difficult when a reference test (gold standard) is available. However, when a gold standard test is not available the Bayesian Latent Class (BLC) Analysis is an effective analytical tool for the estimation of diagnostic accuracy. The aim of this study was to estimate the sensitivity (Se) and specificity (Sp) of four commercial diagnostic kits using BLC. The four diagnostic tests were (1) Merifluor®Direct Fluorecence Antigen (DFA; Giardia/Cryptosporidium; Meridian Diagnostics, Inc., Cincinnati, Ohio), (2) IVD®DFA (Giardia/Cryptosporidium; IDV Research Inc., Carlsbad, CA), (3) IVD Microwell ELISA® (Giardia ; IDV Research Inc., Carlsbad, CA), (4) and IDEXX SNAP® (Giardia ; IDEXX Laboratories Inc., Westbrook, ME). The results from 201 laboratory analysed samples, the prior distributions elicited from three experts, and the consistency of samples as splitting covariate were used as inputs for the BCL models. The estimated Se and Sp of the tests were 87.7% and 97.3% (Merifluor-Cryptosporidium), 68.0% and 99.1% (IVD-Cryptosporidium), 93.6% and 97.9% (Merifluor-Giardia), 96.1% and 97.9% (IVD-Giardia), 86.0% and 98.2% (ELISA-Giardia), and 84.8% and 98.0% (SNAP-Giardia) respectively. The prevalence for non-diarrheic versus diarrheic samples were 2.3% and 4.8% (Cryptosporidium), and 6.9% and 13.5% (Giardia) respectively. We were able to use BLC to assess the sensitivity and specificity of the four commercial diagnostic tests. We ran 36 models and used objective indicators of the performances of the models to choose the best model for estimation of parameters. The results of the study indicated that Merifluor, IVD, and ELISA are equally suitable as diagnostic tests for detection of Giardia. For detection of Cryptosporidium, Merifluor was more accurate than the IVD test.
Advisors/Committee Members: Salman, Mo D. (advisor), Ballweber, Lora (committee member), Lappin, Michael (committee member).
Subjects/Keywords: Bayesian; diagnostic test; sensitivity; specificity; Cryptosporidium; Giardia
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Palomares Velosa, J. E. (2014). Acurracy assessment of four diagnostic tests for the detection of Giardia and Cryptosporidium in the absence of gold standard: a Bayesian approach. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/88550
Chicago Manual of Style (16th Edition):
Palomares Velosa, Jairo Enrique. “Acurracy assessment of four diagnostic tests for the detection of Giardia and Cryptosporidium in the absence of gold standard: a Bayesian approach.” 2014. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/88550.
MLA Handbook (7th Edition):
Palomares Velosa, Jairo Enrique. “Acurracy assessment of four diagnostic tests for the detection of Giardia and Cryptosporidium in the absence of gold standard: a Bayesian approach.” 2014. Web. 05 Mar 2021.
Vancouver:
Palomares Velosa JE. Acurracy assessment of four diagnostic tests for the detection of Giardia and Cryptosporidium in the absence of gold standard: a Bayesian approach. [Internet] [Masters thesis]. Colorado State University; 2014. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/88550.
Council of Science Editors:
Palomares Velosa JE. Acurracy assessment of four diagnostic tests for the detection of Giardia and Cryptosporidium in the absence of gold standard: a Bayesian approach. [Masters Thesis]. Colorado State University; 2014. Available from: http://hdl.handle.net/10217/88550

Colorado State University
11.
Linke, Lyndsey M.
RNA interference as an alternative preventive measure for avian influenza in poultry.
Degree: PhD, Clinical Sciences, 2014, Colorado State University
URL: http://hdl.handle.net/10217/83758
► Avian influenza virus (AIV) is a viral pathogen that causes a wide range of disease in poultry, from subclinical to severe clinical illness and can…
(more)
▼ Avian influenza virus (AIV) is a viral pathogen that causes a wide range of disease in poultry, from subclinical to severe clinical illness and can often result in death. In 1878, AIV was first described as a disease affecting poultry. Nearly 80 years later this disease-causing agent was identified as influenza A virus and a member of the family Orthomyxoviridae. AIV was not considered a significant human pathogen until 1997, when high pathogenic AIV H5N1 emerged from the wildfowl reservoir and was directly transmitted from domestic poultry to humans. Despite a long history of outbreaks in animals, this incident propelled AIV into a globally recognized disease associated with socioeconomic and animal health consequences. Each AIV outbreak highlights ways to improve upon current control strategies and stimulates new ideas for developing novel approaches and technologies to better mitigate AIV outbreaks worldwide. AIV is a dynamic pathogen to study. Host range and adaptation, pathogenicity, pathology, molecular composition, and the epidemiology of AIV all make this virus particularly challenging to control in poultry. Vaccines against AIV are available but the protection they provide for poultry is limited, especially when administered at the onset or in the midst of an outbreak. The most efficacious vaccines must be administered subcutaneously or intramuscularly, an impediment to successfully immunizing large numbers of poultry in a short window of time. Frequently, improper storage and handling leads to vaccine failure. To elicit efficient protection the vaccine must be HA-subtype specific to the outbreak virus. Often stockpiles of vaccines become obsolete and new vaccines must be generated. This is a time consuming process and can take months to secure and additional time to disseminate and administer. In the naive animal, protective antibody production takes two to three weeks to acquire following vaccination. Even if the decision to vaccinate during an outbreak is rapid and an appropriate vaccine is available for immediate use in poultry, vaccination alone would do little to protect against the threat of infection and break the chain of transmission, especially in areas lacking appropriate biosecurity measures. These limitations convey a genuine need to develop a prophylactic that would offer universal protection against any subtype or strain of AIV and would provide rapid protection in the face of an outbreak. Using RNA interference (RNAi) methodologies, this dissertation focuses on developing an innovative antiviral prophylactic that works rapidly to protect poultry against AIV shedding and transmission. The innovation behind this prophylactic technology lies in combining RNAi with the transkingdom RNAi (tkRNAi) delivery platform. This anti-AIV technology specifically targets conserved viral gene segments using small interfering RNA (siRNA) generated and delivered to chicken mucosal respiratory tissues using the tkRNAi system. The work presented in this dissertation details the steps taken to…
Advisors/Committee Members: Salman, Mo (advisor), Landolt, Gabriele (committee member), Olea-Popelka, Francisco (committee member), Wilusz, Jeffrey (committee member).
Subjects/Keywords: antiviral; prophylactic; siRNA; avian influenza; poultry; RNA interference
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Linke, L. M. (2014). RNA interference as an alternative preventive measure for avian influenza in poultry. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/83758
Chicago Manual of Style (16th Edition):
Linke, Lyndsey M. “RNA interference as an alternative preventive measure for avian influenza in poultry.” 2014. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/83758.
MLA Handbook (7th Edition):
Linke, Lyndsey M. “RNA interference as an alternative preventive measure for avian influenza in poultry.” 2014. Web. 05 Mar 2021.
Vancouver:
Linke LM. RNA interference as an alternative preventive measure for avian influenza in poultry. [Internet] [Doctoral dissertation]. Colorado State University; 2014. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/83758.
Council of Science Editors:
Linke LM. RNA interference as an alternative preventive measure for avian influenza in poultry. [Doctoral Dissertation]. Colorado State University; 2014. Available from: http://hdl.handle.net/10217/83758

Colorado State University
12.
Palomares Velosa, Jairo Enrique.
Social ecological determinants of occupational zoonotic disease exposure on Colorado dairy farms.
Degree: PhD, Clinical Sciences, 2019, Colorado State University
URL: http://hdl.handle.net/10217/195289
► The presence of zoonotic pathogens in dairy farms is a known risk for people that work and live in these settings. People who work or…
(more)
▼ The presence of zoonotic pathogens in dairy farms is a known risk for people that work and live in these settings. People who work or live on a farm, farm visitors, service providers, and veterinarians are the most at risks of zoonotic infections. Dairy cattle operations represent a working environment with a high risk of exposure to zoonotic pathogens. The prevention of zoonotic diseases in animal-human interfaces can be challenging. Due to the complexity of the social ecological system, and it requires comprehensive, integrative, and culturally compelling interventions. It has been demonstrated that the behavior of the person at risk can affect their exposure to infectious agents. As demonstrated in other settings, the implementation of consistent and robust preventive measures can change the behavior of persons at risk and success-fully decrease exposure to risk factors. One of the host factors that affect exposure to human infectious diseases is the behavior of the people at risk. The SEM is a theory-based framework that has been used to scientifically explore the complex and interactive personal and environmental factors that affect people's preventive behaviors in specific settings. In general, the aim of epidemiological studies on infectious diseases using the SEM framework is to inform the development or improvement of comprehensive and compelling intervention strategies that directly target the behavior change process at different levels of influence. In this research, we conducted several research activities using the Social Ecological Model (SEM) approach to expand our understanding of host and environmental factors that affect the exposure of zoonotic diseases as work hazards. In the first research chapter (chapter 2) we proposed an SEM with potential factors affecting the preventive behavior of people at risk of zoonotic diseases in dairy farms. In the next chapter, we use this model to build an instrument that measures SE factors for workers of dairy farms and provide sources of validity for that instrument. And in the last research chapter (chapter 4), we identify that self-efficacy and negative workplace perceptions are risk factors of Salmonella Dublin exposure (OR=1.43 [CI 1.11-2.22] & 1.22 [CI 1.02-1.53] respectively) and that knowledge and positive management perceptions were protective factors (OR = 0.90 [CI 0.79-1.00] & 0.91 [CI 0.82-1.00] respectively). Perception of supervisors and coworkers is a protective factor of Campylobacter exposure (OR=0.89 [CI 0.79-0.98]). Based on our observations, a supporting organizational environment, with supervisors and coworkers as deliverers of accurate safety information, and with increased knowledge and understanding of the potential risks and consequences of zoonotic diseases would help to reduce the occupational exposure of zoonotic disease in these farms.
Advisors/Committee Members: Salman, Mo D. (advisor), Roman-Muniz, Ivette N. (advisor), Rao, Sangeeta (committee member), McConnel, Craig (committee member), Reynolds, Stephen (committee member).
Subjects/Keywords: dairy workers; prevention; zoonotic diseases; occupational risks; dairy cattle; social ecological model
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Palomares Velosa, J. E. (2019). Social ecological determinants of occupational zoonotic disease exposure on Colorado dairy farms. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/195289
Chicago Manual of Style (16th Edition):
Palomares Velosa, Jairo Enrique. “Social ecological determinants of occupational zoonotic disease exposure on Colorado dairy farms.” 2019. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/195289.
MLA Handbook (7th Edition):
Palomares Velosa, Jairo Enrique. “Social ecological determinants of occupational zoonotic disease exposure on Colorado dairy farms.” 2019. Web. 05 Mar 2021.
Vancouver:
Palomares Velosa JE. Social ecological determinants of occupational zoonotic disease exposure on Colorado dairy farms. [Internet] [Doctoral dissertation]. Colorado State University; 2019. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/195289.
Council of Science Editors:
Palomares Velosa JE. Social ecological determinants of occupational zoonotic disease exposure on Colorado dairy farms. [Doctoral Dissertation]. Colorado State University; 2019. Available from: http://hdl.handle.net/10217/195289

Colorado State University
13.
McGrew, Ashley Kaye.
Spatial trends of total mercury (THg) exposure, and the role of intestinal helminths on its distribution within piscivorous mammalian hosts.
Degree: PhD, Microbiology, Immunology, and Pathology, 2011, Colorado State University
URL: http://hdl.handle.net/10217/70450
► This research project is unique in that it has explored the interface of three broad disciplines: ecology, toxicology, and parasitology. The primary objectives were to…
(more)
▼ This research project is unique in that it has explored the interface of three broad disciplines: ecology, toxicology, and parasitology. The primary objectives were to determine the role of gastrointestinal (GI) helminths in total mercury (THg) distribution within piscivorous mammalian hosts, and explore the complex interactions that exist within the host GI tract. The project was designed to address these objectives in two pinniped populations: Alaskan ice seals (Phoca largha and Phoca hispida), and California sea lions (Zalophus californianus). Initially, Alaskan gray wolves (Canis lupus) were selected as a reference species for this project, as these animals represent a mammalian definitive host, occupying a top trophic position in a terrestrial food web; nevertheless, preliminary findings demonstrated a subset of these wolves to be subsisting, at least in part, on prey sources of marine origin. Therefore, the project was expanded to include the Alaskan gray wolves as an additional "piscivorous" host for study. At necropsy, host tissues and GI tracts were collected. During GI tract processing, intestinal helminths were removed, weighed, and either saved for identification, or frozen for further analyses. Host tissues (e.g. liver, kidney, cardiac muscle, skeletal muscle), GI lumen contents, and parasites were then analyzed for THg concentrations and stable isotope values (C, N, and S). In Alaskan gray wolves, THg concentrations, and δ13C, δ15N and δ34S isotope values, provided four separate measures supporting the contention that Alaskan gray wolves, with access to marine resources, are relying on piscivory or exploitation of other organisms of marine origin. THg uptake was demonstrated to occur in these animals, and the toxicant-parasite interactions that exist within the GI tract may ultimately affect the host-toxicant interface. The interactions described depend not only on type of parasite and specific toxicant, but also on the complex ecological-like interactions within the host's body. In pinnipeds, parasites were shown to effectively bioaccumulate and/or biomagnify mercury (Hg) within the host GI tract. Within-parasite THg concentrations were not necessarily associated with concentrations in host lumen contents, or host liver and kidney. These data demonstrated that THg distribution in the host is affected by the presence of parasites; consequently, bioavailability of this toxicant to the host may also be affected. A design has been proposed for building an agent-based model, to further explore the interactions described in these studies. This framework will provide a foundation for future work focused on the ecotoxicoparasitology of other related systems.
Advisors/Committee Members: Ballweber, Lora R. (advisor), Salman, Mo D. (advisor), O'Hara, Todd M. (committee member), Clements, Will H. (committee member).
Subjects/Keywords: anisakid; bioaccumulation; mercury; stable isotopes; Corynosoma
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McGrew, A. K. (2011). Spatial trends of total mercury (THg) exposure, and the role of intestinal helminths on its distribution within piscivorous mammalian hosts. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/70450
Chicago Manual of Style (16th Edition):
McGrew, Ashley Kaye. “Spatial trends of total mercury (THg) exposure, and the role of intestinal helminths on its distribution within piscivorous mammalian hosts.” 2011. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/70450.
MLA Handbook (7th Edition):
McGrew, Ashley Kaye. “Spatial trends of total mercury (THg) exposure, and the role of intestinal helminths on its distribution within piscivorous mammalian hosts.” 2011. Web. 05 Mar 2021.
Vancouver:
McGrew AK. Spatial trends of total mercury (THg) exposure, and the role of intestinal helminths on its distribution within piscivorous mammalian hosts. [Internet] [Doctoral dissertation]. Colorado State University; 2011. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/70450.
Council of Science Editors:
McGrew AK. Spatial trends of total mercury (THg) exposure, and the role of intestinal helminths on its distribution within piscivorous mammalian hosts. [Doctoral Dissertation]. Colorado State University; 2011. Available from: http://hdl.handle.net/10217/70450
14.
Dejyong, Tosapol.
Risk analysis of the potential introduction of African swine fever virus into Thailand by pig products from Italy, 2015 (qualitative risk assessment).
Degree: MS(M.S.), Clinical Sciences, 2016, Colorado State University
URL: http://hdl.handle.net/10217/178892
► African swine fever (ASF) is a serious contagious pig disease that produces a wide range of clinical signs and lesions. ASF virus (ASFV), the causative…
(more)
▼ African swine fever (ASF) is a serious contagious pig disease that produces a wide range of clinical signs and lesions. ASF virus (ASFV), the causative agent for ASF, can spread very rapidly. Fortunately, ASF has never been reported in Thailand. The National Institute for Animal Health (NIAH), Department of Livestock Development (DLD) has done an ASF survey and reported zero sero-prevalence. Thailand, however, has imported live pigs and pig products from many countries; most notably in 2015 approximately 4 million kilograms were imported from Italy where ASF outbreaks occurred on the island of Sardinia, Italy during the same year. Since ASF is exotic to Thailand and likely to be introduced into the country, risk analysis can be a tool for estimating the likelihood of an introduction and consequences of the disease, and for revealing any gaps and preparing preventive measures. This study is divided into three sub-studies: assessing risk of ASFV introduction into Thailand by importing pig products from Italy in 2015 – development of an approach, estimation of risks of ASFV introduction into Thailand by importing pig products from Italy, 2015, and qualitative risk assessment of ASFV introduction into Thailand by importing pig products from an endemic country based on different hypothetical scenarios. Also, risk analysis of ASFV of this study should be considered as a model for DLD to improve strategy and policy for preventing new emerging and reemerging diseases. The first step in the process was the development of the conceptual framework of risk analysis composed by generating a general risk pathway and risk question, identifying a hazard, developing a physical pathway and scenario trees, assessing the risk, mitigating the risk, and communicating the risk based on OIE risk analysis for imports. Also, eight possible routes of ASFV introduction were generated by utilizing information from DLD and from scientific publications. Using these routes and the OIE animal disease reporting system and DLD trading database, the specific risk question was generated: "What is the risk of introducing ASFV into Thailand by importing pig products from Italy in 2015?" The second step in the process was analysis of risks according to the risk question and specific pathway based on DLD official documents, the OIE WAHIS database, EU commission decision, EU legislation, EU council directive, exportation and importation requirements and government guidelines, scientific literature, and expert opinions. The potential introduction of ASFV by importing pig products from Italy in 2015 was identified as a hazard to Thailand in the hazard identification step. However, the risk of introduction was deemed "Negligible" by qualitative risk assessment. Risk mitigation giving recommendations to minimize the risk based on weak points identified for the high or moderate likelihood of introduction and significant consequences, and also effective means of communicating the risk, was provided. The third step in the process was qualitative risk assessment in…
Advisors/Committee Members: Salman, Mo D. (advisor), Rao, Sangeeta (advisor), Hadrich, Joleen (committee member), Wongsathapornchai, Kachen (committee member).
Subjects/Keywords: Italy; risk analysis; Thailand; pig products; risk assessment; African swine fever
…78
APPENDIX 1. Institutional review board (IRB) Colorado State University… …65
Figure 5.1.
The letter of approval by institutional review board Colorado State… …University...86
Figure 5.2.
Requirements for the importation of pork and its edible products into…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dejyong, T. (2016). Risk analysis of the potential introduction of African swine fever virus into Thailand by pig products from Italy, 2015 (qualitative risk assessment). (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/178892
Chicago Manual of Style (16th Edition):
Dejyong, Tosapol. “Risk analysis of the potential introduction of African swine fever virus into Thailand by pig products from Italy, 2015 (qualitative risk assessment).” 2016. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/178892.
MLA Handbook (7th Edition):
Dejyong, Tosapol. “Risk analysis of the potential introduction of African swine fever virus into Thailand by pig products from Italy, 2015 (qualitative risk assessment).” 2016. Web. 05 Mar 2021.
Vancouver:
Dejyong T. Risk analysis of the potential introduction of African swine fever virus into Thailand by pig products from Italy, 2015 (qualitative risk assessment). [Internet] [Masters thesis]. Colorado State University; 2016. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/178892.
Council of Science Editors:
Dejyong T. Risk analysis of the potential introduction of African swine fever virus into Thailand by pig products from Italy, 2015 (qualitative risk assessment). [Masters Thesis]. Colorado State University; 2016. Available from: http://hdl.handle.net/10217/178892
15.
Erales Villamil, José Alberto.
Silvopastoral system for sustainable cattle production in the tropics of Mexico.
Degree: PhD, Clinical Sciences, 2017, Colorado State University
URL: http://hdl.handle.net/10217/185751
► Traditional production system has exhausted natural resources and depleted soil nutrients reducing farm productivity and forcing farmers to expand farm lands, which, increases deforestation and…
(more)
▼ Traditional production system has exhausted natural resources and depleted soil nutrients reducing farm productivity and forcing farmers to expand farm lands, which, increases deforestation and pollution. Global warming and an increasing global population pose additional strain to the already fragile global food security, making it urgent for innovative production systems to be developed. Such systems, adapted to local circumstances and designed to reduce deforestation and increase food production, must emerge to provide an expanding global food demand while enabling preservation of natural resources. In Mexico, a five-year research project, derived from a national initiative has proposed a silvopastoral model for the Tepalcatepec valley, in the
State of Michoacan, as an alternative to conventional livestock ranching in the tropics. The primary objective for this research project was to characterize the advantages and disadvantages of an alternative livestock farming model, the silvopastoral system. One hundred and fifteen farmers in the Tepalcatepec valley were surveyed to characterize their farms, their family demographics, main cattle breed, crops farmed, cattle diet, measures of animal performance (productivity) commercialization (marketing practices) and animal health management practices. An analysis of the progress of the various national SPS initiatives was also performed in order to identify gaps in research, collaboration, stakeholder education, and application of SPS farming in Mexico. A systems analysis was conducted on the research project using the information compiled from the team of scientists surveyed. Components related to carbon capture, biodiversity, soil quality, nutrient recycling, and larger-scale cycles such as water cycle need to be incorporated into future research. An accurate measure of the true economic and ecological impact of SPS farming is an essential goal. Improved communication among scientists, government agencies, and stakeholders is also essential for successful research into SPS farming. The animal health component of the five-year Mexican national SPS project is the focus of this dissertation. Traditional livestock health practices on participating small farms were characterized, and common health problems of cattle were identified. A community based livestock syndromic surveillance system was developed, implemented, and observed for two years on five selected farms. Observations from farmers and veterinarians were triangulated to validate data on animal health collected by laypeople. For each farm under study, monthly cumulative incidence per animal category (calf, grower or adult), the most frequent disease syndrome, and the syndrome that carried the greatest economic impact were calculated. Most Rho correlation coefficients for farmer's and veterinarian's observations were high. Farmers that implemented the silvopastoral model were considered typical of those who practiced this farming method elsewhere within the region. Because participating farms shared production system,…
Advisors/Committee Members: Salman, Mo (advisor), Reid, Robin S. (committee member), Solorio Sánchez, Francisco J. (committee member), Van Metre, David C. (committee member), Zepeda, Cristobal (committee member).
Subjects/Keywords: Mexico; risk analysis; system analysis; participatory epidemiology; bovine tuberculosis; silvopastoral
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APA (6th Edition):
Erales Villamil, J. A. (2017). Silvopastoral system for sustainable cattle production in the tropics of Mexico. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/185751
Chicago Manual of Style (16th Edition):
Erales Villamil, José Alberto. “Silvopastoral system for sustainable cattle production in the tropics of Mexico.” 2017. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/185751.
MLA Handbook (7th Edition):
Erales Villamil, José Alberto. “Silvopastoral system for sustainable cattle production in the tropics of Mexico.” 2017. Web. 05 Mar 2021.
Vancouver:
Erales Villamil JA. Silvopastoral system for sustainable cattle production in the tropics of Mexico. [Internet] [Doctoral dissertation]. Colorado State University; 2017. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/185751.
Council of Science Editors:
Erales Villamil JA. Silvopastoral system for sustainable cattle production in the tropics of Mexico. [Doctoral Dissertation]. Colorado State University; 2017. Available from: http://hdl.handle.net/10217/185751

Colorado State University
16.
Mullaney, Sara Beth.
Burden of acute gastrointestinal illness and foodborne illness caused by five major pathogens among nondeployed active duty US Army service members 2014-2015, The.
Degree: PhD, Clinical Sciences, 2016, Colorado State University
URL: http://hdl.handle.net/10217/176654
Subjects/Keywords: foodborne illness; burden of gastrointestinal illness
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Mullaney, S. B. (2016). Burden of acute gastrointestinal illness and foodborne illness caused by five major pathogens among nondeployed active duty US Army service members 2014-2015, The. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/176654
Chicago Manual of Style (16th Edition):
Mullaney, Sara Beth. “Burden of acute gastrointestinal illness and foodborne illness caused by five major pathogens among nondeployed active duty US Army service members 2014-2015, The.” 2016. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/176654.
MLA Handbook (7th Edition):
Mullaney, Sara Beth. “Burden of acute gastrointestinal illness and foodborne illness caused by five major pathogens among nondeployed active duty US Army service members 2014-2015, The.” 2016. Web. 05 Mar 2021.
Vancouver:
Mullaney SB. Burden of acute gastrointestinal illness and foodborne illness caused by five major pathogens among nondeployed active duty US Army service members 2014-2015, The. [Internet] [Doctoral dissertation]. Colorado State University; 2016. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/176654.
Council of Science Editors:
Mullaney SB. Burden of acute gastrointestinal illness and foodborne illness caused by five major pathogens among nondeployed active duty US Army service members 2014-2015, The. [Doctoral Dissertation]. Colorado State University; 2016. Available from: http://hdl.handle.net/10217/176654

Colorado State University
17.
Ketusing, Naree.
Evaluation of strategies for eradication of Aujeszky's disease (Pseudorabies) in commercial swine farms in Chiang-Mai and Lampoon provinces, Thailand.
Degree: MS(M.S.), Clinical Sciences, 2010, Colorado State University
URL: http://hdl.handle.net/10217/41261
► Several strategies for eradicating Aujeszky's disease (Pseudorabies) in Chiang-Mai and Lampoon Provinces, Thailand, were compared using a computer simulation model, the North American Animal Disease…
(more)
▼ Several strategies for eradicating Aujeszky's disease (Pseudorabies) in Chiang-Mai and Lampoon Provinces, Thailand, were compared using a computer simulation model, the North American Animal Disease Spread Model (NAADSM). The duration of the outbreak, the number of infected herdss and the number destroyed herds were compared during these simulated outbreaks. Destruction, zoning for restricted movement and improved detection and vaccination strategies were studied. Destruction was found to be the most effective method to eradicate Pseudorabies. Although zoning and ring vaccination did not influence this model, the recommendations from this study are to apply both destruction and three zone (3, 8 and 16 kilometers) restricted movements along with enhanced detection and a 16 vaccination ring.
Advisors/Committee Members: Salman, Mo (advisor), Olea-Popelka, Francisco (advisor), Keefe, Thomas (committee member).
Subjects/Keywords: Aujeszky's disease in swine – Thailand – Chiang Mai (Province); Aujeszky's disease in swine – Thailand – Lamphun (Province)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Ketusing, N. (2010). Evaluation of strategies for eradication of Aujeszky's disease (Pseudorabies) in commercial swine farms in Chiang-Mai and Lampoon provinces, Thailand. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/41261
Chicago Manual of Style (16th Edition):
Ketusing, Naree. “Evaluation of strategies for eradication of Aujeszky's disease (Pseudorabies) in commercial swine farms in Chiang-Mai and Lampoon provinces, Thailand.” 2010. Masters Thesis, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/41261.
MLA Handbook (7th Edition):
Ketusing, Naree. “Evaluation of strategies for eradication of Aujeszky's disease (Pseudorabies) in commercial swine farms in Chiang-Mai and Lampoon provinces, Thailand.” 2010. Web. 05 Mar 2021.
Vancouver:
Ketusing N. Evaluation of strategies for eradication of Aujeszky's disease (Pseudorabies) in commercial swine farms in Chiang-Mai and Lampoon provinces, Thailand. [Internet] [Masters thesis]. Colorado State University; 2010. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/41261.
Council of Science Editors:
Ketusing N. Evaluation of strategies for eradication of Aujeszky's disease (Pseudorabies) in commercial swine farms in Chiang-Mai and Lampoon provinces, Thailand. [Masters Thesis]. Colorado State University; 2010. Available from: http://hdl.handle.net/10217/41261

Colorado State University
18.
Zaheer, Muhammad Usman.
Simulation modeling as a tool for the control of Foot-and-Mouth Disease (FMD) in endemic regions.
Degree: PhD, Clinical Sciences, 2019, Colorado State University
URL: http://hdl.handle.net/10217/199823
To view the abstract, please see the full text of the document.
Advisors/Committee Members: Rao, Sangeeta (advisor), Salman, Mo D. (advisor), Steneroden, Katie (committee member), Weber, Steve (committee member), Magzamen, Sheryl (committee member).
Subjects/Keywords: endemic countries; foot-and-mouth disease; stochastic simulation; food security; animal health; spatially-explicit
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zaheer, M. U. (2019). Simulation modeling as a tool for the control of Foot-and-Mouth Disease (FMD) in endemic regions. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/199823
Chicago Manual of Style (16th Edition):
Zaheer, Muhammad Usman. “Simulation modeling as a tool for the control of Foot-and-Mouth Disease (FMD) in endemic regions.” 2019. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/199823.
MLA Handbook (7th Edition):
Zaheer, Muhammad Usman. “Simulation modeling as a tool for the control of Foot-and-Mouth Disease (FMD) in endemic regions.” 2019. Web. 05 Mar 2021.
Vancouver:
Zaheer MU. Simulation modeling as a tool for the control of Foot-and-Mouth Disease (FMD) in endemic regions. [Internet] [Doctoral dissertation]. Colorado State University; 2019. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/199823.
Council of Science Editors:
Zaheer MU. Simulation modeling as a tool for the control of Foot-and-Mouth Disease (FMD) in endemic regions. [Doctoral Dissertation]. Colorado State University; 2019. Available from: http://hdl.handle.net/10217/199823

Colorado State University
19.
Havas, Karyn Alicia.
Systemic review of brucellosis in the Kakheti region of the country of Georgia: an evaluation of the disease ecology, risk factors and suggestions for disease control, A.
Degree: PhD, Clinical Sciences, 2011, Colorado State University
URL: http://hdl.handle.net/10217/52062
To view the abstract, please see the full text of the document.
Advisors/Committee Members: Salman, Mo D. (advisor), Hill, Ashley E. (committee member), Magennis, Ann L. (committee member), Callan, Robert J. (committee member), Gillette, Shana C. (committee member).
Subjects/Keywords: agent based model; zoonotic; rapid assessment; Brucellosis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Havas, K. A. (2011). Systemic review of brucellosis in the Kakheti region of the country of Georgia: an evaluation of the disease ecology, risk factors and suggestions for disease control, A. (Doctoral Dissertation). Colorado State University. Retrieved from http://hdl.handle.net/10217/52062
Chicago Manual of Style (16th Edition):
Havas, Karyn Alicia. “Systemic review of brucellosis in the Kakheti region of the country of Georgia: an evaluation of the disease ecology, risk factors and suggestions for disease control, A.” 2011. Doctoral Dissertation, Colorado State University. Accessed March 05, 2021.
http://hdl.handle.net/10217/52062.
MLA Handbook (7th Edition):
Havas, Karyn Alicia. “Systemic review of brucellosis in the Kakheti region of the country of Georgia: an evaluation of the disease ecology, risk factors and suggestions for disease control, A.” 2011. Web. 05 Mar 2021.
Vancouver:
Havas KA. Systemic review of brucellosis in the Kakheti region of the country of Georgia: an evaluation of the disease ecology, risk factors and suggestions for disease control, A. [Internet] [Doctoral dissertation]. Colorado State University; 2011. [cited 2021 Mar 05].
Available from: http://hdl.handle.net/10217/52062.
Council of Science Editors:
Havas KA. Systemic review of brucellosis in the Kakheti region of the country of Georgia: an evaluation of the disease ecology, risk factors and suggestions for disease control, A. [Doctoral Dissertation]. Colorado State University; 2011. Available from: http://hdl.handle.net/10217/52062
.