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You searched for +publisher:"Cal Poly" +contributor:("Matthew A. Burd"). Showing records 1 – 2 of 2 total matches.

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Cal Poly

1. Bowen, Amber Jean. Bone Density Measurement via Radiographic Calibration.

Degree: MS, Animal Science, 2010, Cal Poly

Musculoskeletal injuries are the most common injuries sustained by athletes and military recruits and can result in decreased performance and lifelong disability. So common and costly are these injuries that the American Academy of Orthopedic Surgeons has provided guidelines for future research, including recommendations for the development of a large animal model of bone injury (USDA 2001). In human and veterinary medicine, digital radiography represents the primary diagnostic tool the physician uses to diagnose skeletal injury. Advances in digital radiography have provided the veterinarian with opportunities to make both simple and complex radiographic assessments. We investigated a simple quantitative measurement of the solar, concave aspect of the distal phalanx in the horse, termed the Palmar-Metric (PM). The PM was a significant predictor of solar cup volume (p < 0.001) and negatively correlated with age (r2 = 0.28, p < 0.05) as determined from 544 radiographs of the distal phalanx from the left and right front feet. Therefore, veterinarians should be aware of the age related change in the solar, concave aspect of the distal phalanx in the horse. We hypothesized that the decrease in the degree of concavity with age may be due to demineralization and subsequent loss of bone density along the solar margin of the distal phalanx. Therefore, we investigated the quantification of optical bone density (bone OD) via complex radiographic calibration. By developing a brightness/darkness index (BDI), the greyscale of radiographs, calibrated with an aluminum marker of varying known thickness, can be compared to the average density of a cross-section of bone. At varying radiographic exposure intensity (kV) and exposure time (mAs), Al BDI was a significant predictor of bone BDI (r2 = 0.960, p < 0.001) and bone OD (r2 = 0.971, p < 0.001). This method of calibration can be utilized by the radiologist to accurately assess bone OD regardless of technique, and allow direct comparison of radiographs taken under different exposure settings. This method successfully quantifies bone OD via measurement of BDI from standardized digital radiographs, allowing for the opacity of radiographs to be truly comparable when taken under different circumstances. Advisors/Committee Members: Matthew A. Burd.

Subjects/Keywords: digital; radiograph; bone; optical density; Radiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Bowen, A. J. (2010). Bone Density Measurement via Radiographic Calibration. (Masters Thesis). Cal Poly. Retrieved from https://digitalcommons.calpoly.edu/theses/341 ; 10.15368/theses.2010.108

Chicago Manual of Style (16th Edition):

Bowen, Amber Jean. “Bone Density Measurement via Radiographic Calibration.” 2010. Masters Thesis, Cal Poly. Accessed August 20, 2019. https://digitalcommons.calpoly.edu/theses/341 ; 10.15368/theses.2010.108.

MLA Handbook (7th Edition):

Bowen, Amber Jean. “Bone Density Measurement via Radiographic Calibration.” 2010. Web. 20 Aug 2019.

Vancouver:

Bowen AJ. Bone Density Measurement via Radiographic Calibration. [Internet] [Masters thesis]. Cal Poly; 2010. [cited 2019 Aug 20]. Available from: https://digitalcommons.calpoly.edu/theses/341 ; 10.15368/theses.2010.108.

Council of Science Editors:

Bowen AJ. Bone Density Measurement via Radiographic Calibration. [Masters Thesis]. Cal Poly; 2010. Available from: https://digitalcommons.calpoly.edu/theses/341 ; 10.15368/theses.2010.108


Cal Poly

2. Gearhart, Richard O. The Effect of Embryo Biopsy and Vitrification on the Development Potential of Equine Embryos.

Degree: MS, Animal Science, 2009, Cal Poly

This study investigated the development potential of equine embryos in vitro after biopsy and vitrification. Twenty embryos were obtained from Quarter Horse, Thoroughbred, and mix-breed light mares between three and ten years old. The twenty embryos were divided into a biopsy (n=10) and control group (n=10). The biopsy group underwent microaspiration biopsy using a micromanipulator to obtain a small tissue sample from the embryo. Both groups were then vitrified using a commercially available technique originally described by Carnevale (2006) at Colorado State University. All 20 embryos were cultured in DMEM/Hams F-12 medium under oil at 37°C in 5% CO2 in air (Hinrichs et al., 1990). Embryos were monitored for expansion and hatching. Embryo development was statistically different between the two groups (p<0.05). The biopsy procedure did result in a much lower development potential in the biopsy group as compared to the control group (20% vs. 80%). However, embryos in the biopsy group did show expansion and hatching therefore the combined procedure did not preclude development potential in vitro. Based on these findings, more research needs to be done to increase the success of the combined procedure and the ultimate viability of the embryos needs to be confirmed with the establishment of successful pregnancies. Advisors/Committee Members: Matthew A. Burd.

Subjects/Keywords: vitrification; embryo biopsy; microaspiration; micromanipulation; embryo culture; equine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Gearhart, R. O. (2009). The Effect of Embryo Biopsy and Vitrification on the Development Potential of Equine Embryos. (Masters Thesis). Cal Poly. Retrieved from https://digitalcommons.calpoly.edu/theses/208 ; 10.15368/theses.2009.177

Chicago Manual of Style (16th Edition):

Gearhart, Richard O. “The Effect of Embryo Biopsy and Vitrification on the Development Potential of Equine Embryos.” 2009. Masters Thesis, Cal Poly. Accessed August 20, 2019. https://digitalcommons.calpoly.edu/theses/208 ; 10.15368/theses.2009.177.

MLA Handbook (7th Edition):

Gearhart, Richard O. “The Effect of Embryo Biopsy and Vitrification on the Development Potential of Equine Embryos.” 2009. Web. 20 Aug 2019.

Vancouver:

Gearhart RO. The Effect of Embryo Biopsy and Vitrification on the Development Potential of Equine Embryos. [Internet] [Masters thesis]. Cal Poly; 2009. [cited 2019 Aug 20]. Available from: https://digitalcommons.calpoly.edu/theses/208 ; 10.15368/theses.2009.177.

Council of Science Editors:

Gearhart RO. The Effect of Embryo Biopsy and Vitrification on the Development Potential of Equine Embryos. [Masters Thesis]. Cal Poly; 2009. Available from: https://digitalcommons.calpoly.edu/theses/208 ; 10.15368/theses.2009.177

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