You searched for +publisher:"Brown University" +contributor:("Ling, Xinsheng")
.
Showing records 1 – 11 of
11 total matches.
No search limiters apply to these results.
1.
Miao, Wang.
Nonlinear Transport in Solid-State Nanopores.
Degree: PhD, Physics, 2015, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:419425/
► Research on DNA translocation through nanopore has drawn much attention because of its potential in DNA sequencing and biosensing. A lot of issues about translocation…
(more)
▼ Research on DNA translocation through nanopore has
drawn much attention because of its potential in DNA sequencing and
biosensing. A lot of issues about translocation process have been
found in recent years, such as capture kinetics, thermal
fluctuations, electro-osmotic flow, etc. Due to the flexibility of
DNA molecules, there are many complicated folded translocation
events, which make the task of data analysis difficult. Here we use
semi-flexible fd virus as a model system for studying translocation
dynamics. The fd virus has persistent length around several
micrometers, larger than the diameter of a nanopore, making folded
translocation unlikely. In our study, distinct types of
translocation events have been observed and a scheme of
classification is developed. We also observe the subtle difference
in their translocation dynamics of wild and mutant types of fd
viruses due to different degrees of flexibility measured by their
persistent length. A systematic method of measuring the current
drops and time intervals for the fd translocations is developed and
is used to construct a scatter plot, the latter led to the
discovery of the Stotz-Wien effect in nanopore, nonlinear
electrophoresis in strong electric field. The Stotz-Wien effect is
studied with different types of virus and under different measuring
salt concentrations. From comparison between experimental results
and theoretic prediction, we found that electro-osmotic flow (EOF)
is very crucial to the translocation process. We studied the EOF
around different shaped particles and as well as within nanopores
through numerical approach by using Poisson-Nernst-Planck (PNP)
model. From our calculation, we confirm that Stotz-Wien effect is a
consequence of polarized Debye cloud caused by the strong electric
field. Finally, we show that the non-uniform distributed EOF within
nanopore plays a very important role in translocation process,
which should be considered when designing sequence
method.
Advisors/Committee Members: Ling, Xinsheng (Director), Tang, Jay (Reader), Feldman, Dmitri (Reader).
Subjects/Keywords: solid-state nanopore
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Miao, W. (2015). Nonlinear Transport in Solid-State Nanopores. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:419425/
Chicago Manual of Style (16th Edition):
Miao, Wang. “Nonlinear Transport in Solid-State Nanopores.” 2015. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:419425/.
MLA Handbook (7th Edition):
Miao, Wang. “Nonlinear Transport in Solid-State Nanopores.” 2015. Web. 26 Jan 2021.
Vancouver:
Miao W. Nonlinear Transport in Solid-State Nanopores. [Internet] [Doctoral dissertation]. Brown University; 2015. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:419425/.
Council of Science Editors:
Miao W. Nonlinear Transport in Solid-State Nanopores. [Doctoral Dissertation]. Brown University; 2015. Available from: https://repository.library.brown.edu/studio/item/bdr:419425/
2.
YU, LICHAO.
Defects in Two Dimensional Colloidal Crystals.
Degree: PhD, Physics, 2015, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:419422/
► We use digital video microscopy to study the defects in two-dimensional colloidal crystals (2DCC). A crystalline solid, different from its liquid state, preserves long-wavelength shear…
(more)
▼ We use digital video microscopy to study the defects
in two-dimensional colloidal crystals (2DCC). A crystalline solid,
different from its liquid state, preserves long-wavelength shear
rigidity and broken symmetry. Questions about how shear rigidity
and long-range order disappear during melting, are unresolved in
terms of the complication of defect structures and their roles in
crystal melting, especially in two dimension. Colloidal crystals
(CC) serve as a promising model system to directly observe the
defects under optical microscope. In our first study, we report the
effects of vacancies and interstitials on the phonon modes in a
2DCC. By applying the equipartition theorem, we extract the
dispersion relation of the lattice vibrations using real-time video
microscopy. We find that both longitudinal and transverse modes in
the spectrum are softened by the existence of point defects.
Second, we investigate the diffusion process of interstitials in a
2DCC. The motion is viewed as gliding of both edge dislocations
along one of the crystalline axes. The microscopic process is
equivalently a point mass overcoming Peierls barrier with an
exponential escaping time. We also establish a new criterion to
determine the ergodicity of a defect system and discover the
nonergodic behavior of di-interstitials.
Advisors/Committee Members: LING, XINSHENG (Director), KOSTERLITZ, JOHN (Reader), PELCOVITS, ROBERT (Reader).
Subjects/Keywords: Defects
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
YU, L. (2015). Defects in Two Dimensional Colloidal Crystals. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:419422/
Chicago Manual of Style (16th Edition):
YU, LICHAO. “Defects in Two Dimensional Colloidal Crystals.” 2015. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:419422/.
MLA Handbook (7th Edition):
YU, LICHAO. “Defects in Two Dimensional Colloidal Crystals.” 2015. Web. 26 Jan 2021.
Vancouver:
YU L. Defects in Two Dimensional Colloidal Crystals. [Internet] [Doctoral dissertation]. Brown University; 2015. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:419422/.
Council of Science Editors:
YU L. Defects in Two Dimensional Colloidal Crystals. [Doctoral Dissertation]. Brown University; 2015. Available from: https://repository.library.brown.edu/studio/item/bdr:419422/
3.
Hanson, Helen A.
The Crystallography of Vortex Matter in a Niobium
Crystal.
Degree: PhD, Physics, 2012, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:297704/
► The vortex matter in type-II superconductors continues to be a subject of great fascination in condensed matter physics. A longstanding theoretical and experimental problem is…
(more)
▼ The vortex matter in type-II superconductors continues
to be a subject of great fascination in condensed matter physics. A
longstanding theoretical and experimental problem is the
identification of the ground state of the vortex lines in the
presence of quenched atomic disorder which acts as random pinning
centers. A possible edge contamination model has been proposed as a
mechanism behind the seemingly contradictory experimental results
for the ordered state of matter. This model could also explain the
lack of universality for the peak effect behavior exhibited in
samples with otherwise similar phase diagrams. Using a novel
neutron diffraction technique, we report structural evidence for
this edge contamination mechanism. This high-resolution method is
used to study the fine structure of the vortex matter in a niobium
crystal with a weak peak effect and a disordered zero-field-cooled
vortex matter. We find this disordered state is metastable and that
it can be restructured through a thermal cycling procedure. The
results are explained in a strained lattice framework. We then
perform Reverse Monte Carlo Refinements on our neutron scattering
data and the possible vortex structures for our crystal agree with
experimental results from an approach that combines spatial
information with reciprocal space scattering. Having confirmed the
existence of an edge contamination mechanism in this sample, we
oxidize the surface in order to reduce the impact of the
inhomogeneous surface barrier. By repeating our neutron diffraction
measurements, we find that oxidation process has smoothed the
magnetic field profile through the sample and improves the overall
structural order of the zero-field-cooled vortex matter. On the
other hand, the field-cooled vortex matter structure should be
independent of any edge contamination effect but surprisingly, this
scattering intensity in fact doubles after surface oxidation. This
result suggests that there is another source of disorder in the
niobium crystal that has been affected. We discuss our results in
the context of the peak effect and Bragg glass
models.
Advisors/Committee Members: Ling, Xinsheng (Director), Kosterlitz, James (Reader), Mitrovic, Vesna (Reader).
Subjects/Keywords: vortex phyiscs
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hanson, H. A. (2012). The Crystallography of Vortex Matter in a Niobium
Crystal. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:297704/
Chicago Manual of Style (16th Edition):
Hanson, Helen A. “The Crystallography of Vortex Matter in a Niobium
Crystal.” 2012. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:297704/.
MLA Handbook (7th Edition):
Hanson, Helen A. “The Crystallography of Vortex Matter in a Niobium
Crystal.” 2012. Web. 26 Jan 2021.
Vancouver:
Hanson HA. The Crystallography of Vortex Matter in a Niobium
Crystal. [Internet] [Doctoral dissertation]. Brown University; 2012. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:297704/.
Council of Science Editors:
Hanson HA. The Crystallography of Vortex Matter in a Niobium
Crystal. [Doctoral Dissertation]. Brown University; 2012. Available from: https://repository.library.brown.edu/studio/item/bdr:297704/
4.
Wang, Xi.
3D Neutron Diffraction Studies on the Vortex Lattice.
Degree: PhD, Physics, 2012, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:297705/
► In condensed matter physics the vortex lattice of type-II superconductors provides a prototype for studying the effect of random pinning on elastic systems. One important…
(more)
▼ In condensed matter physics the vortex lattice of
type-II superconductors provides a prototype for studying the
effect of random pinning on elastic systems. One important problem
is to understand the structural transition from a theoretically
predicted ordered Bragg glass phase to a disordered vortex liquid
phase. Defects, such as screw dislocations, should play an
important role in mediating this order-disorder transition. It is
important to confirm the existence of these defect structures in
the vortex lattice. Experimentally it is difficult to probe the
detailed defect structures inside the vortex lattice. Traditional
methods can only provide information on the surface configuration
or an averaged picture of the bulk behavior of the vortex lattice.
Here we use a novel high-resolution neutron diffraction technique
to probe the angular orientation of the lattice planes as the flux
lines traverse the atomic crystal. Our results provide structural
evidence for screw dislocations inside the vortex lattice. The
anisotropic defect structure in the underlying atomic lattice
serves as a symmetry breaking field for the vortex lattice. The
strong dependence of the vortex lattice structure on the growth
procedure reveals that the system is metastable and can be
perturbed through thermal cycling to a possible ground state. We
measure the structure of the vortex lattice under different applied
magnetic fields and temperatures to study the interplay between
vortex-vortex interaction, vortex-atomic lattice interaction, and
thermal fluctuations. This high-resolution neutron diffraction
technique opens up a new way in studying the detailed structure of
the vortex lattice. Our results suggest that the vortex lattice in
low temperature superconductors with anisotropic defects in the
atomic lattice could be an excellent candidate for exploring the
entangled flux liquid phase.
Advisors/Committee Members: Ling, Xinsheng (Director), Kosterlitz, J. (Reader), Mitrovic, Vesna (Reader).
Subjects/Keywords: neutron diffraction
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wang, X. (2012). 3D Neutron Diffraction Studies on the Vortex Lattice. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:297705/
Chicago Manual of Style (16th Edition):
Wang, Xi. “3D Neutron Diffraction Studies on the Vortex Lattice.” 2012. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:297705/.
MLA Handbook (7th Edition):
Wang, Xi. “3D Neutron Diffraction Studies on the Vortex Lattice.” 2012. Web. 26 Jan 2021.
Vancouver:
Wang X. 3D Neutron Diffraction Studies on the Vortex Lattice. [Internet] [Doctoral dissertation]. Brown University; 2012. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:297705/.
Council of Science Editors:
Wang X. 3D Neutron Diffraction Studies on the Vortex Lattice. [Doctoral Dissertation]. Brown University; 2012. Available from: https://repository.library.brown.edu/studio/item/bdr:297705/
5.
Jung, Hyeyun.
Thermal Diffusion Shock Waves in a Linear Temperature Field
and Comparison of Ultrasonic Distillation to Sparging of Liquid
Mixtures.
Degree: PhD, Physics, 2012, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:297708/
► The Ludwig-Soret effect, also known as thermal diffusion, refers to the separation of mixtures in a temperature gradient. Thermal diffusion is governed by a pair…
(more)
▼ The Ludwig-Soret effect, also known as thermal
diffusion, refers to the separation of mixtures in a temperature
gradient. Thermal diffusion is governed by a pair of coupled
differential equations which reduce to a nonlinear partial
differential equation when the temperature profile is specified.
Here two solutions are given to the partial differential equation
describing thermal diffusion in a linear temperature field where
the components are constrained in space. The first solution
considers thermal diffusion without the effects of mass diffusion
and shows the underlying motion of the components of the mixture to
be that of shock waves. The second solution is an exact solution of
the Ludwig-Soret equation that includes both the effect of the
thermal gradient and mass diffusion. An additional solution is
found for the problem of thermal diffusion in unbounded space. A
new experimental method was developed to monitor distributions of
components of the mixture in a linear temperature field based on
probing a cell containing fluorescent nanoparticles with a confocal
microscope. The nanoparticles were chemically synthesized and
labeled with a fluorophore that absorbed 488 nm radiation and
fluoresced at a 520 nm peak. The temperature gradient in the cell
was generated by cooling one surface of the cell, a sapphire plate,
with flowing water and electrically heating the other surface,
which was an indium tin oxide coated glass plate. The dynamics of
the separation of the mixture was recorded by monitoring
fluorescence from the particles with the scanning confocal
microscope. Data were fitted to a new numerical solution to the
full partial differential equation for thermal diffusion with mass
diffusion included. The method developed here is shown to provide
Soret parameters, including the thermal diffusion factor and the
Soret coefficient, based on either a single recording of the
terminal density fraction profile, or by fitting the density
profile at several times with the results of numerical integration.
Ultrasonic distillation was investigated. Experiments were carried
out to verify the recently reported, perfect separation of ethanol
from water by ultrasonic distillation. Ultrasonic distillation
refers to the application of intense ultrasound to a liquid
resulting in the formation of an ultrasonic fountain that generates
both mist and vapor. Here, the composition of the vapor and aerosol
above an ultrasonic fountain was determined as a function of
irradiation time and compared with the results of sparging for five
different solutions. The experimental apparatus for determining the
efficiency of separation consists of a glass vessel containing a
piezoelectric transducer driven at either 1.65 or 2.40 MHz. Dry
nitrogen was passed over the ultrasonic fountain to remove the
vapor and aerosol. The composition of the liquid solutions
remaining in the apparatus were recorded following irradiation
using gas chromatography, refractive index measurement, nuclear
magnetic resonance, or spectrophotometry as diagnostics for the…
Advisors/Committee Members: Diebold, Gerald (Director), Ling, Xinsheng (Reader), Valles, James (Reader).
Subjects/Keywords: Thermal Diffusion
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jung, H. (2012). Thermal Diffusion Shock Waves in a Linear Temperature Field
and Comparison of Ultrasonic Distillation to Sparging of Liquid
Mixtures. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:297708/
Chicago Manual of Style (16th Edition):
Jung, Hyeyun. “Thermal Diffusion Shock Waves in a Linear Temperature Field
and Comparison of Ultrasonic Distillation to Sparging of Liquid
Mixtures.” 2012. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:297708/.
MLA Handbook (7th Edition):
Jung, Hyeyun. “Thermal Diffusion Shock Waves in a Linear Temperature Field
and Comparison of Ultrasonic Distillation to Sparging of Liquid
Mixtures.” 2012. Web. 26 Jan 2021.
Vancouver:
Jung H. Thermal Diffusion Shock Waves in a Linear Temperature Field
and Comparison of Ultrasonic Distillation to Sparging of Liquid
Mixtures. [Internet] [Doctoral dissertation]. Brown University; 2012. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:297708/.
Council of Science Editors:
Jung H. Thermal Diffusion Shock Waves in a Linear Temperature Field
and Comparison of Ultrasonic Distillation to Sparging of Liquid
Mixtures. [Doctoral Dissertation]. Brown University; 2012. Available from: https://repository.library.brown.edu/studio/item/bdr:297708/
6.
Obeid, Dina N.
Noisy Stabilized Kuramoto-Sivashinsky: A modelfor studying
state selection in far fromequilibrium systems.
Degree: PhD, Physics, 2011, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:11168/
► In this thesis we address the question of pattern selection in spatially extendedsystems in the presence of stochastic noise. As a model equation, we study…
(more)
▼ In this thesis we address the question of pattern
selection in spatially extendedsystems in the presence of
stochastic noise. As a model equation, we study the1D stabilized
Kuramoto Sivashinsky equation with additive uncorrelated
stochasticnoise. This equation is one of the simplest nonlinear
equations that has a variety ofsecondary and even tertiary
instabilities. We focus our attention on static stationarystates
that are stable against the Eckhaus secondary instability. In the
presence ofnoise the Eckhaus stable band of the deterministic
equation collapses to a narrowregion near the center of the band.
This is consistent with the behavior of the phasediffusion
constants of these states. Some connections to the phenomenon of
stateselection in driven out of equilibrium systems are
made.
Advisors/Committee Members: Kosterlitz, J. Michael (Director), Pelcovits, Robert (Reader), Ling, Xinsheng Sean (Reader), Guralnik, Gerald (Reader).
Subjects/Keywords: Nonequilibrium
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Obeid, D. N. (2011). Noisy Stabilized Kuramoto-Sivashinsky: A modelfor studying
state selection in far fromequilibrium systems. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:11168/
Chicago Manual of Style (16th Edition):
Obeid, Dina N. “Noisy Stabilized Kuramoto-Sivashinsky: A modelfor studying
state selection in far fromequilibrium systems.” 2011. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:11168/.
MLA Handbook (7th Edition):
Obeid, Dina N. “Noisy Stabilized Kuramoto-Sivashinsky: A modelfor studying
state selection in far fromequilibrium systems.” 2011. Web. 26 Jan 2021.
Vancouver:
Obeid DN. Noisy Stabilized Kuramoto-Sivashinsky: A modelfor studying
state selection in far fromequilibrium systems. [Internet] [Doctoral dissertation]. Brown University; 2011. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:11168/.
Council of Science Editors:
Obeid DN. Noisy Stabilized Kuramoto-Sivashinsky: A modelfor studying
state selection in far fromequilibrium systems. [Doctoral Dissertation]. Brown University; 2011. Available from: https://repository.library.brown.edu/studio/item/bdr:11168/
7.
Dong, Ankun.
Single-molecule Nanoscopy of RNA Polymerase II Transcription
at a Single Gene in Live Cells.
Degree: Department of Physics, 2017, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:733314/
► Single-molecule approaches enable us to follow the movement, interactions and conformational dynamics of individual molecules in real-time, thus providing novel insights in complex biochemical systems…
(more)
▼ Single-molecule approaches enable us to follow the
movement, interactions and conformational dynamics of individual
molecules in real-time, thus providing novel insights in complex
biochemical systems that have remained masked in the ensemble
averaging of traditional bulk biochemical approaches. Recent
advances in single-molecule tracking, fluorescence spectroscopy and
subdiffraction optical microscopy have unveiled unprecedented views
of molecular processes in live cells. To extract quantitative
information from individual molecules in the high background noise,
these techniques are often based on in vitro reconstituted systems
with either surface-immobilized or freely-diffusing biomolecules in
dilute conditions. Live cell, real-time imaging, tracking and
counting biomolecules in their native, crowded intracellular
environment currently remain an extremely challenging task. Based
on the numerical simulation, I built the real time tracking 3D STED
nanoscopy enabling single molecule detection. With the new
technique, I perform oligo-nucleotide hybridization detection
experiment in vitro as well as study the mechanism of RNA
Polymerase II transcription in living cells at single molecule
level. Basically, I reveal the accumulation of Pol II molecules and
quantified nearly 10 Pol II molecules in the cluster during active
transcription at a tagged mini-gene in the native environment. In
addition, mini-gene transcription does not involve transient Pol II
clustering at pre-initiation by kinetic analysis enabled by
target-locking overVII multiple transcription rounds, arguing
against the persistence of accumulated Pol IIs in the absence of
transcription or extensive Pol II recycling-related spatial
compartmentalization. What’s more, I find that single Pol II
molecules are stochastically recruited from the nucleoplasm, enter
into productive elongation and are predominantly released instead
of recycled upon termination. The results set up a quantitative
framework for investigating Pol II dynamics at single genes at
single molecule level, and also demonstrate that the potential and
powerful use of real time tracking 3D STED nanoscopy in elucidating
the complex biological mechanisms in vivo.
Advisors/Committee Members: Ling, Xinsheng Sean (Advisor), Kosterlitz, J. Michael (Reader), Diebold, Gerald J. (Reader).
Subjects/Keywords: Molecular biology
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dong, A. (2017). Single-molecule Nanoscopy of RNA Polymerase II Transcription
at a Single Gene in Live Cells. (Thesis). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:733314/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dong, Ankun. “Single-molecule Nanoscopy of RNA Polymerase II Transcription
at a Single Gene in Live Cells.” 2017. Thesis, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:733314/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dong, Ankun. “Single-molecule Nanoscopy of RNA Polymerase II Transcription
at a Single Gene in Live Cells.” 2017. Web. 26 Jan 2021.
Vancouver:
Dong A. Single-molecule Nanoscopy of RNA Polymerase II Transcription
at a Single Gene in Live Cells. [Internet] [Thesis]. Brown University; 2017. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:733314/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dong A. Single-molecule Nanoscopy of RNA Polymerase II Transcription
at a Single Gene in Live Cells. [Thesis]. Brown University; 2017. Available from: https://repository.library.brown.edu/studio/item/bdr:733314/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
8.
Luo, Xu.
Thermodynamic Studies of Phase Transitions and Emerging
Orders in Unconventional Superconductors.
Degree: PhD, Physics, 2015, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:419516/
► The nematic phase transition in Fe-based superconductors (FeSCs) has been a topic under intensive investigation. So far it is commonly accepted that the structural transition…
(more)
▼ The nematic phase transition in Fe-based
superconductors (FeSCs) has been a topic under intensive
investigation. So far it is commonly accepted that the structural
transition from tetragonal (C4) to orthorhombic (C2) symmetry in
FeSCs has an electronic nematic origin due to the unusual
anisotropy in resistivity, optical conductivity and orbital
occupancy observed above the structural transition. However, recent
studies of (Ba, Eu)Fe2(As1-xPx)2 by magnetic torque measurements
show the existence of a “true” nematic transition well above the
commonly accepted structural/nematic transition .Controversies
about this “true” nematic phase transition arise as residue strains
or external applied fields are known to break C4 symmetry and
render the structural transition merely a crossover. We performed
high resolution AC micro-calorimetry and SQUID magnetometry
measurements of BaFe2(As1-xPx)2 (x=0, 0.3) to investigate the
various phase transitions and to explore the “true” nematic phase
transition. The advantageous design of our membrane calorimeter
allows us to perform high resolution studies of the thermodynamic
phase transitions without any symmetry breaking fields. Our results
suggest that there is not a second order “true” nematic phase
transition in BaFe2(As1-xPx)2 even though the Ginzburg-Landau model
used to fit the magnetic torque data indicates that the expected
thermal anomaly should be within our experimental resolution. In
addition to the above, we present specific heat and magnetization
studies of Ba1-xNaxFe2As2 in search of the recent discovered
emergent reentrant C2 to C4 symmetry SDW transition in this series
of compound. Our results indeed locate a new phase transition in
Ba0.74Na0.26Fe2As2 at 45K. However, the absence of the conventional
SDW transition at around 80K in our data leaves doubt about the
exact nature of this new phase transition. We also systematically
studied the effects of heavy ion irradiation (HII) on the
anisotropy of YBCO single crystals by angular rotation specific
heat measurements. We found that the anisotropy of YBCO decreases
by approximately a factor of two with an irradiation dose of 6T
(matching field). The dependence of anisotropy on irradiation doses
agrees well with the prediction from a simple phenomenological
model that takes into account the anisotropic scattering caused by
columnar defects created in HII.
Advisors/Committee Members: Ling, Xinsheng (Director), Welp, Ulrich (Director), Marston, John (Reader), Mitrovic, Vesna (Reader).
Subjects/Keywords: Fe-based superconductor
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Luo, X. (2015). Thermodynamic Studies of Phase Transitions and Emerging
Orders in Unconventional Superconductors. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:419516/
Chicago Manual of Style (16th Edition):
Luo, Xu. “Thermodynamic Studies of Phase Transitions and Emerging
Orders in Unconventional Superconductors.” 2015. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:419516/.
MLA Handbook (7th Edition):
Luo, Xu. “Thermodynamic Studies of Phase Transitions and Emerging
Orders in Unconventional Superconductors.” 2015. Web. 26 Jan 2021.
Vancouver:
Luo X. Thermodynamic Studies of Phase Transitions and Emerging
Orders in Unconventional Superconductors. [Internet] [Doctoral dissertation]. Brown University; 2015. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:419516/.
Council of Science Editors:
Luo X. Thermodynamic Studies of Phase Transitions and Emerging
Orders in Unconventional Superconductors. [Doctoral Dissertation]. Brown University; 2015. Available from: https://repository.library.brown.edu/studio/item/bdr:419516/
9.
McFarland, James M.
Single-Neuron and Network Dynamics in the
Neocortical-Entorhinal-Hippocampal Circuit.
Degree: PhD, Physics, 2011, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:11242/
► The neocortical-entorhinal-hippocampal circuit has been shown to play an important role in memory formation and consolidation. Furthermore, the entorhinal cortex (EC) and the hippocampus are…
(more)
▼ The neocortical-entorhinal-hippocampal circuit has
been shown to play an important role in memory formation and
consolidation. Furthermore, the entorhinal cortex (EC) and the
hippocampus are thought to be key components of the brain�s spatial
processing system. I examine both of these aspects using
quantitative analysis of single-neuron and network activity. In
part 1, I investigate the dynamics of the
neocortical-entorhinal-hippocampal circuit in anesthetized mice
where cortical neurons alternate between a depolarized and spiking
�UP� state and a hyperpolarized and quiescent �DOWN� state. I first
demonstrate an explicit-duration hidden Markov model algorithm for
inferring UP-DOWN states (UDS) from both membrane potential and
local field potential recordings. I then apply this method to study
UDS in superficial neurons of the medial and lateral EC (MEC and
LEC). MEC, but not LEC, neurons are shown to selectively decouple
from the neocortical UDS and exhibit persistent UP states whose
duration is quantized in units of neocortical UDS cycles. In
contrast, LEC, but not MEC, neurons are found to display periods of
pronounced 2-4Hz oscillations which are phase-locked to the ongoing
UDS. In part 2, I examine the hippocampal �rate� and �temporal�
codes for position in freely behaving mice. The spatial and
temporal firing properties of hippocampal neurons in GluA1 knockout
(KO) mice are found to be dramatically altered relative to
wild-type mice, and the network theta and gamma oscillations are
also markedly reduced in the KO animals. I then examine the
precession of hippocampal neurons� spike phase relative to the
theta rhythm, and demonstrate a novel dependence of the temporal
code on behavior. These studies reveal important mechanisms by
which the EC could shape neocortical-hippocampal interactions
during sleep, and advance our understanding of how the hippocampal
�rate� and �temporal� codes are generated and relate to
behavior.
Advisors/Committee Members: Mehta, Mayank (Director), Stein, Derek (Director), Stein, Derek (Reader), Ling, Xinsheng (Reader), Mehta, Mayank (Director), Stein, Derek (Director), Stein, Derek (Reader), Ling, Xinsheng (Reader).
Subjects/Keywords: UP-DOWN states
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McFarland, J. M. (2011). Single-Neuron and Network Dynamics in the
Neocortical-Entorhinal-Hippocampal Circuit. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:11242/
Chicago Manual of Style (16th Edition):
McFarland, James M. “Single-Neuron and Network Dynamics in the
Neocortical-Entorhinal-Hippocampal Circuit.” 2011. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:11242/.
MLA Handbook (7th Edition):
McFarland, James M. “Single-Neuron and Network Dynamics in the
Neocortical-Entorhinal-Hippocampal Circuit.” 2011. Web. 26 Jan 2021.
Vancouver:
McFarland JM. Single-Neuron and Network Dynamics in the
Neocortical-Entorhinal-Hippocampal Circuit. [Internet] [Doctoral dissertation]. Brown University; 2011. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:11242/.
Council of Science Editors:
McFarland JM. Single-Neuron and Network Dynamics in the
Neocortical-Entorhinal-Hippocampal Circuit. [Doctoral Dissertation]. Brown University; 2011. Available from: https://repository.library.brown.edu/studio/item/bdr:11242/
10.
Stewart, Michael D.
Superconductor to Insulator Transitions in Amorphous
Nanohoneycomb Films.
Degree: PhD, Physics, 2008, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:48/
► Two dimensional electronic systems exhibit a wide variety of phenomena including the quantum Hall effect, weak and strong localization, and metal-insulator transitions, including the superconductor…
(more)
▼ Two dimensional electronic systems exhibit a wide
variety of phenomena including the quantum Hall effect, weak and
strong localization, and metal-insulator transitions, including the
superconductor to insulator transition (SIT). In each case the
possibility of a universal explanation, independent of the
microscopic details of the system, has tantalized researchers. In
some cases, such as the temperature dependence of the conductance
of metal films, or the spacing of resistance plateaus in the Hall
effect, universal behavior is without doubt. Universal explanations
of the amorphous film SIT revolve around the dirty Boson model, in
which the sharp rise in the resistance of a film at low temperature
is due to the localization of Cooper pairs. The existence of
long-lived Cooper pairs in an electrically insulating system, the
central assumption of the model, has remained in doubt because some
measurements support the assertion and others refute it. This
thesis addresses this experimental dissonance by investigating the
SITs of amorphous Bismuth films perforated with a regular
nanohoneycomb (NHC) array of holes. The nanoscale perforations
allow a direct measurement of phase coherent Cooper pairs with an
applied magnetic field. On the insulating side of the disorder
driven SIT the resistance as a function of magnetic field
oscillates with a period, h/2eS, where S is the area of a unit cell
of holes. The 2e period betrays the presence of localized Cooper
pairs in an electrically insulating state. The magnetoresistance of
weak superconducting films reveals several SITs which qualitatively
resemble the disorder driven SIT. The behavior of these transitions
borrows heavily from both sides of a dichotomy exhibited by
different materials through their field driven SITs. NHC films show
activated resistances and a large peak in the magnetoresistance,
analogous to the more spectacular behavior of some materials.
However, they also show a weak, almost metallic, temperature
dependence for a range of fields near the SIT, not unlike the
metallic phase of unpatterned Bismuth and other materials. These
results suggest that an underlying multiply connected geometry in
ostensibly amorphous, unpatterned films may account for some of the
range of material dependent behavior.
Advisors/Committee Members: Valles, James (director), Feldman, Dima (reader), Ling, Xinsheng (reader).
Subjects/Keywords: superconductor insulator transition
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Stewart, M. D. (2008). Superconductor to Insulator Transitions in Amorphous
Nanohoneycomb Films. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:48/
Chicago Manual of Style (16th Edition):
Stewart, Michael D. “Superconductor to Insulator Transitions in Amorphous
Nanohoneycomb Films.” 2008. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:48/.
MLA Handbook (7th Edition):
Stewart, Michael D. “Superconductor to Insulator Transitions in Amorphous
Nanohoneycomb Films.” 2008. Web. 26 Jan 2021.
Vancouver:
Stewart MD. Superconductor to Insulator Transitions in Amorphous
Nanohoneycomb Films. [Internet] [Doctoral dissertation]. Brown University; 2008. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:48/.
Council of Science Editors:
Stewart MD. Superconductor to Insulator Transitions in Amorphous
Nanohoneycomb Films. [Doctoral Dissertation]. Brown University; 2008. Available from: https://repository.library.brown.edu/studio/item/bdr:48/
11.
Wu, Shanshan.
Fabrication of nanopore systems and their application to DNA
manipulation.
Degree: PhD, Physics, 2008, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:28/
► Nanopore system is important for its many promising applications in rapid DNA sequencing, large biological molecule detection, polynucleotide-enzyme interaction study and etc. Following the first…
(more)
▼ Nanopore system is important for its many promising
applications in rapid DNA sequencing, large biological molecule
detection, polynucleotide-enzyme interaction study and etc.
Following the first introduction of nanopores for polynucleotide
study twelve years ago, many research studies have focused on the
development of synthetic nanopore systems, due to its adjustability
and adaptability for meeting various application needs, and the
potential integration into future nano devices. Given the broad
potential technological importance, it's highly desirable to
develop a reliable yet convenient fabrication method for nanopore
system. We introduce a novel fast and low-cost technique for
fabricating nanopore system with soft materials, employing a
low-power laser with lithography-free substrate preparation. A
model of surface-tension driven mass flow is proposed to describe
its mechanism of formation. We further demonstrate the soft
nanopore system's capability for sensing biological molecules with
DNA characterization experiments. A solid-state nanopore based
system with optical access is introduced for the purpose of
manipulating DNA-tethered microspheres near the nanopore using
optical tweezers. We use optical trap to anchor lambda-DNA-tethered
microspheres in close proximity (1 - 3 um) to the solid-state
nanopore, and study the ionic conductance through the
voltage-biased nanopore. At high voltage (-100 mV to -300 mV ), we
observe hundreds of free-DNA-translocation-like current
suppressions. We present the finding and discuss its possible
underlying mechanism.
Advisors/Committee Members: Ling, Xinsheng (director), Tang, Jay (reader), Stein, Derek (reader).
Subjects/Keywords: Nanopores
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wu, S. (2008). Fabrication of nanopore systems and their application to DNA
manipulation. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:28/
Chicago Manual of Style (16th Edition):
Wu, Shanshan. “Fabrication of nanopore systems and their application to DNA
manipulation.” 2008. Doctoral Dissertation, Brown University. Accessed January 26, 2021.
https://repository.library.brown.edu/studio/item/bdr:28/.
MLA Handbook (7th Edition):
Wu, Shanshan. “Fabrication of nanopore systems and their application to DNA
manipulation.” 2008. Web. 26 Jan 2021.
Vancouver:
Wu S. Fabrication of nanopore systems and their application to DNA
manipulation. [Internet] [Doctoral dissertation]. Brown University; 2008. [cited 2021 Jan 26].
Available from: https://repository.library.brown.edu/studio/item/bdr:28/.
Council of Science Editors:
Wu S. Fabrication of nanopore systems and their application to DNA
manipulation. [Doctoral Dissertation]. Brown University; 2008. Available from: https://repository.library.brown.edu/studio/item/bdr:28/
.