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Title Dynamic Simulation and Neuromuscular Control of Movement: Applications for Predictive Simulations of Balance Recovery
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Publication Date
Degree Level doctoral
University/Publisher University of Tennessee – Knoxville
Abstract Balance is among the most challenging tasks for patients with movement disorders. Study and treatment of these disorders could greatly benefit from combined software tools that offer better insights into neuromuscular biomechanics, and predictive capabilities for optimal surgical and rehabilitation treatment planning. A platform was created to combine musculoskeletal modeling, closed-loop forward dynamic simulation, optimization techniques, and neuromuscular control system design. Spinal (stretch-reflex) and supraspinal (operational space task-based) controllers were developed to test simulation-based hypotheses related to balance recovery and movement control. A corrective procedure (rectus femoris transfer surgery) was targeted for children experiencing stiff-knee gait and how this procedure may affect their balance recovery. Clinical movement analysis and simulation-based approaches were combined to understand the biomechanical consequences of this surgical procedure. The closed-loop controller was extended by merging approaches from robotics and biomechanics. A prioritized multi-task, support-consistent, task-based controller was implemented inside the simulation platform to synthesize human balance. The simulated results were validated with experimental data of healthy adults by defining surrogate response surfaces that represent the patients’ primary tasks (e.g., to keep their balance) as function of defined subtasks (e.g. swing leg positions or torso orientations). The potential of using this platform to study, predict functional outcomes and perhaps improve treatments for musculoskeletal conditions is exciting and valuable. This project not only integrates software tools, but also allows integration of neuroscientists, physiologists, biomechanists, and physical therapists to adopt, adapt, and generate new solutions for musculoskeletal conditions.
Subjects/Keywords Dynamic Simulation of human movement; Neuromuscular control; Rectus Femoris Transfer surgery in children with cerebral palsy; balance recovery simulations; predictive simulation of movement; synthesizing human balance; Biomechanical Engineering; Controls and Control Theory; Dynamics and Dynamical Systems; Movement and Mind-Body Therapies; Rehabilitation and Therapy; Robotics; Surgical Procedures, Operative
Country of Publication us
Format application/pdf
Record ID oai:trace.tennessee.edu:utk_graddiss-4696
Repository utk-diss
Date Retrieved
Date Indexed 2019-01-07

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…4 Specific Aims ................................................................................................................... 6 CHAPTER 2 A PLATFORM FOR DYNAMIC SIMULATION AND CONTROL OF MOVEMENT BASED ON OPENSIM AND MATLAB…

…INTERFACE LINKS THE RAPID MODEL-BASED DESIGN AND CONTROL SYSTEMS STRENGTHS OF MATLAB/SIMULINK WITH THE NUMERICAL SIMULATION AND HUMAN MOVEMENT DYNAMICS STRENGTHS OF OPENSIM. (B) FLOWCHART ILLUSTRATING STAGES FOR EACH SIMULINK SIMULATION. (C…

…into the complex interaction between neural commands, musculoskeletal geometry, and the resulting functional movements. Combining clinical movement analysis and simulation-based approaches may lead to a better understanding of biomechanical consequences…

of different human movement disorders and its treatments. 1 1.2. Simulation Paradigm Forward dynamics simulations of human movement require consideration of the many individual elements involved in the control of human motion. These individual…

…predict functional outcomes using pre-treatment data. Simulation is a vital tool for multidisciplinary study of human movement control because it can 3 provide fundamental insights into the causes of movement and can point the way to optimal treatment…

…best possible simulation results, but also has a potential to transform the biomechanics research field Furthermore, simulation and control of human movement is a challenging problem that requires simultaneous knowledge of human anatomy and physiology…

…outcomes are not likely to improve. Combining clinical movement analysis and simulation-based approaches may lead to a better understanding of biomechanical consequences of stiff-knee gait and its treatments. The first objective of this study was to develop…

…consequences of a commonly used surgical intervention, and to examine how 6 predictive simulations that synthesize normal healthy movement can identify the biomechanical factors that may affect postural responses. Next, the balance recovery simulations were…

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