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Title Evaluation of a Microfluidic Mixer Utilizing Staggered Herringbone Channels: A Computational Fluid Dynamics Approach
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Publication Date
Degree MSin Chemical Engineering
Discipline/Department Washkewicz College of Engineering
Degree Level masters
University/Publisher Cleveland State University
Abstract Microfluidic platforms offer a variety of advantages including improved heat transfer, low working volumes, ease of scale-up, and strong user control on parameters. However, flow within microfluidic channels occurs at low Reynolds numbers, which makes mixing difficult to accomplish. Adding V-shaped ridges to channel walls, a pattern called the staggered herringbone design (SHB), might alleviate this problem by introducing transverse flow patterns that enable enhanced mixing. However, certain factors affecting the SHB mixer’s performance remain largely unexplored.In this work, a microfluidic mixer utilizing the SHB geometry was developed and characterized using computational fluid dynamics based simulations and complimentary experiments. A channel design with SHB ridges was simulated in COMSOL Multiphysics under a variety of operating conditions to evaluate its mixing capabilities. The device was fabricated using soft-lithography to experimentally observe the mixing process. The mixing was visualized by pumping fluorescent dyes through the device and imaging the channels using a confocal microscope.The device was found to efficiently mix fluids rapidly, based on both simulations and experiments. Varying the Reynolds number or component diffusion coefficients had a weak effect on the mixing profile, due to the laminar flow regime and insufficient residence time, respectively. Mixing effectiveness decreased as the component flow rate ratio increased. Fluid flow patterns visualized in confocal microscope images were highly identical to the simulated results, suggesting that the simulations serve as good predictors of the device’s performance. This SHB mixer design would be a good candidate for further implementation as a reactor.
Subjects/Keywords Chemical Engineering; microfluidics; mixing; computational fluid dynamics; comsol; staggered herringbone
Contributors Kothapalli, Chandra (Committee Chair)
Language en
Rights unrestricted ; This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
Country of Publication us
Format application/pdf
Record ID oai:etd.ohiolink.edu:csu1503954013980881
Repository ohiolink
Date Retrieved
Date Indexed 2017-09-11
Grantor Cleveland State University

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